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Review Open Access

Novel applications of platelet concentrates in tissue regeneration (Review)

  • Authors:
    • Zhen-Yu Ding
    • Ying Tan
    • Qian Peng
    • Jun Zuo
    • Ning Li
  • View Affiliations / Copyright

    Affiliations: Hunan Key Laboratory of Oral Health Research, Hunan 3D Printing Engineering Research Center of Oral Care, Hunan Clinical Research Center of Oral Major Diseases and Oral Health, Xiangya Stomatological Hospital, Xiangya School of Stomatology, Central South University, Changsha, Hunan 410008, P.R. China, Department of Blood Transfusion, Xiangya Hospital, Clinical Transfusion Research Center, Central South University, Changsha, Hunan 410008, P.R. China
    Copyright: © Ding et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 226
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    Published online on: January 18, 2021
       https://doi.org/10.3892/etm.2021.9657
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Abstract

Numerous studies have explored the suitability of biocompatible materials in regenerative medicine. Platelet concentrates are derived from centrifuged blood and are named according to their biological characteristics, such as platelet-rich plasma, platelet-rich fibrin and concentrated growth factor. Platelet concentrates have gained considerable attention in soft and hard tissue engineering. Indeed, multiple components of autologous platelet concentrates, such as growth factors, fibrin matrix and platelets, serve essential roles in wound healing. Current studies are focused on cutting-edge strategies to meet the requirements for tissue restoration by improving the properties of autologous platelet concentrates. In the present review, applications of platelet concentrates for tissue engineering are discussed, presenting a selection of recent advances and novel protocols. In addition, several aspects of these strategies, such as the advantages of lyophilized platelet concentrates and the combination of platelet concentrates with biomaterials, stem cells or drugs are discussed. The present review aims to summarize novel strategies using platelet concentrates to improve the outcomes of wound healing.
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Copy and paste a formatted citation
Spandidos Publications style
Ding Z, Tan Y, Peng Q, Zuo J and Li N: Novel applications of platelet concentrates in tissue regeneration (Review). Exp Ther Med 21: 226, 2021.
APA
Ding, Z., Tan, Y., Peng, Q., Zuo, J., & Li, N. (2021). Novel applications of platelet concentrates in tissue regeneration (Review). Experimental and Therapeutic Medicine, 21, 226. https://doi.org/10.3892/etm.2021.9657
MLA
Ding, Z., Tan, Y., Peng, Q., Zuo, J., Li, N."Novel applications of platelet concentrates in tissue regeneration (Review)". Experimental and Therapeutic Medicine 21.3 (2021): 226.
Chicago
Ding, Z., Tan, Y., Peng, Q., Zuo, J., Li, N."Novel applications of platelet concentrates in tissue regeneration (Review)". Experimental and Therapeutic Medicine 21, no. 3 (2021): 226. https://doi.org/10.3892/etm.2021.9657
Copy and paste a formatted citation
x
Spandidos Publications style
Ding Z, Tan Y, Peng Q, Zuo J and Li N: Novel applications of platelet concentrates in tissue regeneration (Review). Exp Ther Med 21: 226, 2021.
APA
Ding, Z., Tan, Y., Peng, Q., Zuo, J., & Li, N. (2021). Novel applications of platelet concentrates in tissue regeneration (Review). Experimental and Therapeutic Medicine, 21, 226. https://doi.org/10.3892/etm.2021.9657
MLA
Ding, Z., Tan, Y., Peng, Q., Zuo, J., Li, N."Novel applications of platelet concentrates in tissue regeneration (Review)". Experimental and Therapeutic Medicine 21.3 (2021): 226.
Chicago
Ding, Z., Tan, Y., Peng, Q., Zuo, J., Li, N."Novel applications of platelet concentrates in tissue regeneration (Review)". Experimental and Therapeutic Medicine 21, no. 3 (2021): 226. https://doi.org/10.3892/etm.2021.9657
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