Long‑term histological results of ossicular chain reconstruction using bioceramic implants
- Horia Mocanu
- Adela-Ioana Mocanu
- Ana Miruna Drăgoi
- Marian Rădulescu
Affiliations: Department of ENT&HNS, Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania, Department of ENT&HNS, Bucharest Emergency University Hospital, 050098 Bucharest, Romania, Department of Neuropsychiatry, Alexandru Obregia Clinical Hospital of Psychiatry, 041902 Bucharest, Romania, Department of ENT&HNS, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania
- Published online on: January 25, 2021 https://doi.org/10.3892/etm.2021.9692
Copyright: © Mocanu
et al. This is an open access article distributed under the
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Middle ear problems are addressed using tympanoplasty, which requires a mobile tympanic membrane and secure sound-conducting mechanism. The present is a long‑term, retrospective, non‑controlled study on the results of ossiculoplasty using bioceramic implants of autochthonous origin and which defined the statistical relevant factors that could influence the rate of implant rejection. In a cohort of 108 patients ossiculoplasties with bioceramic implants were performed and patients were followed up clinically for a period of minimum 7 years. Several factors were identified that could influence the results of the implantation and the statistical correlations were studied. The rejection rate after 9.12 years was 21% (23 patients). Histological integration rate was 79% (85 patients), similar to results reported in literature for both bioceramic and titanium implants. Hydroxyapatite has many of the ideal characteristics required to be a good prosthesis with a high degree of biocompatibility, very low extrusion rate, low risk of disease transmission and good functional results. Although perhaps considered of historical interest, bioceramic implants are cheaper and can be produced locally, which is a great advantage for struggling economies.