Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
March-2022 Volume 23 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March-2022 Volume 23 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report Open Access

Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report

  • Authors:
    • Alina-Georgiana Vulcu Cordunianu
    • Gabriel Ganea
    • Mihai Alexandru Cordunianu
    • Daniel Cochior
  • View Affiliations / Copyright

    Affiliations: Medicine Doctoral School, Titu Maiorescu University, 040317 Bucharest, Romania, ENT Department, Carol Davila Central University Emergency Military Hospital, 10825 Bucharest, Romania
    Copyright: © Vulcu Cordunianu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 195
    |
    Published online on: January 5, 2022
       https://doi.org/10.3892/etm.2022.11118
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Squamous cell carcinoma (SCC) of the hypopharynx is associated with the worst prognosis of all squamous cell cancer types of the head and neck, with a rich submucosal lymphatic network and a significant inferior extent. Generally, cancers of the head and neck have a big impact on the quality of life (QoL) in patients, both before and after treatment, due to the fact that most cases are diagnosed in advanced stages, with lymph node metastases and have an aggressive pattern associated with low survival rates. The present case report aimed to see the evolution of a patient successfully treated for hypopharyngeal cancer with conservation therapies from the QoL perspective and the influence made by the presence of tracheostomy. Variables, including clinical parameters (sex, age, TNM classification, performance status, histological type and tumor subsite), local control, QoL, Adult Comorbidity Evaluation‑27 score and overall survival were assessed, according to the American Joint Committee on Cancer 8th edition, for a 58‑year‑old patient treated with conservation therapies and tracheostomy in a tertiary center. Subjective features measured through the QoL questionnaire had scores with lowering tendencies during the treatment period. The patient was provided with early training for tracheostomy care and early discharge education. The following objective features of treatment response were exhibited: Hemoglobin levels, leukocyte count, tumor size, imagistic evaluations and local control to confirm treatment response. It is essential when planning the treatment of aggressive and rare pathologies, such as hypopharyngeal cancer, to consider the QoL and patient choice for better adherence. Overall, the results demonstrated that the initial requirement for emergency tracheostomy was not associated with any ulterior complications and did not influence the end result of the treatment.
View Figures

Figure 1

Figure 2

View References

1 

Vila PM and Uppaluri R: Neoplasms of the hypopharynx and cervical esophagus. In: Cummings Otolaryngology Head and Neck Surgery. Flint PW and Cummings CW (eds). 6th edition, Vol II. pp1537-1553, Elsevier Saunders, Philadelphia, 2015.

2 

Firkins J, Hansen L, Driessnack M and Dieckmann N: Quality of life in ‘cronic’ cancer survivors: A meta-analysis. J Cancer Survivorship. 14:504–517. 2020.PubMed/NCBI View Article : Google Scholar

3 

Lewandowska A, Rudzki G, Lewandowski T, Prochnicki M, Rudzki S, Laskowska B and Brudniak J: Quality of life of cancer patients treated with chemotherapy. Int J Environ Res Public Health. 17(6938)2020.PubMed/NCBI View Article : Google Scholar

4 

Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L and Gregoire V: EHNS Executive Board. Electronic address: simplesecretariat@ehns.org; ESMO Guidelines Committee. Electronic address: simpleclinicalguidelines@esmo.org and ESTRO Executive Board. Electronic address: simpleinfo@estro.org. Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 31:1462–1475. 2020.PubMed/NCBI View Article : Google Scholar

5 

Marchlang JL, Luce D, Leclerc A, Goldberg P, Orlowski E, Bugel I and Brugère J: Laryngeal and hypopharyngeal cancer and occupational exposure to asbestos and man-made vitreous fibers: Results of a case-control study. Am J Ind Med. 37:581–589. 2000.PubMed/NCBI View Article : Google Scholar

6 

Laforest L, Luce D, Goldberg P, Begin D, Gerin M, Demers PA, Brugere K and Leclerc A: Laryngeal and hypopharyngeal cancers and occupational exposure to formaldehyde and various dusts: A case-control study in France. Occup Environ Med. 57:767–773. 2000.PubMed/NCBI View Article : Google Scholar

7 

Neagu A, Mocanu A, Bonciu A, Coada G and Mocanu H: Prevalence of GJB2 gene mutations correlated to presence of clinical and environmental risk factors in the etiology of congenital sensorineural hearing loss of the Romanian population. Exp Ther Med. 21(612)2021.PubMed/NCBI View Article : Google Scholar

8 

Petersen JF, Timmermans AJ, van Dijk BAC, Overbeek LIH, Smit LA, Hilgers FJM, Stuiver MM and van den Brekel MWM: Trends in treatment, incidence and survival of hypopharynx cancer: A 20-year population-based study in the Netherlands. Eur Arch Otorhinolaryngol. 275:181–189. 2018.PubMed/NCBI View Article : Google Scholar

9 

Arends CR, Petersen JF, van der Noort V, Timmermans AJ, Leemans CR, de Bree R, Van den Brekel MWM and Stuiver MM: Survival predictions of hypopharynx cancer: Development of a clinical prediction model. Laryngoscope. 130:2166–2172. 2020.PubMed/NCBI View Article : Google Scholar

10 

Monteiro AR, Garcia AR, Pereira TC, Macedo F, Soares RF, Pereira K, Serra T, Khouri L, Ribeiro J and Teixeira MM: ACE-27 as a prognostic tool of severe acute toxicities in patients with head and neck cancer treated with chemoradiotherapy: A real-world, prospective, observational study. Support Care Cancer. 29:1863–1871. 2021.PubMed/NCBI View Article : Google Scholar

11 

Friedlander AH and Ettinger RL: Karnofsky performance status scale. Spec Care Dentist. 29:147–148. 2009.PubMed/NCBI View Article : Google Scholar

12 

Singer S, Arraras JI, Chie WC, Fisher SE, Galalae R, Hammerlid E, Nicolatou-Galitis O, Schmalz C, Verdonck-de Leeuw I, Gamper E, et al: Performance of the EORTC questionnaire for the assessment of quality of life in head and neck cancer patients EORTC QLQ-H&N35: A methodological review. Qual Life Res. 22:1927–1941. 2013.PubMed/NCBI View Article : Google Scholar

13 

American Joint Committee on Cancer: Oropharynx and hypopharynx. In: AJCC Cancer Staging Manual. 8th edition. Springer, New York, NY, p16123-16135, 2017.

14 

Seyman CC and Celik SS: Effect of protective cover on the quality of life of patients with tracheostomy-A quasi-experimental study. J Perianesth Nurs. 35:430–436. 2020.PubMed/NCBI View Article : Google Scholar

15 

Colandrea M and Eckardt P: Improving tracheostomy care delivery: Instituting clinical care pathways and nursing education to improve patient outcomes. ORL Head Neck Nurs. 34:7–16. 2016.PubMed/NCBI

16 

Lim SH, Sun JM, Hong J, Oh D, Ahn YC, Chung MK, Jeong HS, Son YI, Ahn MJ, Baek CH, et al: Induction chemotherapy followed by concurrent chemoradiotherapy versus CCRT for locally advanced hypopharynx and base of tongue cancer. Korean J Intern Med. 36 (Suppl 1):S217–S224. 2021.PubMed/NCBI View Article : Google Scholar

17 

Yokota T, Shibata M, Hamauchi S, Shirasu H, Onozawa Y, Ogawa H, Onoe T, Kawakami T, Turuta M, Inoue H, et al: Feasibility and efficacy of chemoradiotherapy with concurrent split-dose cisplatin after induction chemotherapy with docetaxel/cisplatin/5-fluorouracil for locally advanced head and neck cancer. Mol Clin Oncol. 13(35)2020.PubMed/NCBI View Article : Google Scholar

18 

Pezdirec M, Strojan P and Boltezar IH: Swallowing disorders after treatment for head and neck cancer. Radiol Oncol. 53:225–230. 2019.PubMed/NCBI View Article : Google Scholar

19 

Sherman AC, Simonton S, Adams DC, Vural E, Owens B and Hanna E: Assessing quality of life in patients with head and neck cancer: cross-validation of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Head and Neck module (QLQ-H&N35). Arch Otolaryngol Head Neck Surg. 126:459–467. 2000.PubMed/NCBI View Article : Google Scholar

20 

Gomes EPAA, Aranha AMF, Borges AH and Volpato LER: Head and Neck cancer Patients' quality of life: Analysis of three instruments. J Dent (Shiraz). 21:31–41. 2020.PubMed/NCBI View Article : Google Scholar

21 

Milne S, Parmar J and Ong TK: Adult comorbidity Evaluation-27 as a predictor of postoperative complications, two-year mortality, duration of hospital stay, and readmission within 30 days in patients with squamous cell carcinoma of the head and neck. Br J Oral Maxillofac Surg. 57:214–218. 2019.PubMed/NCBI View Article : Google Scholar

22 

Mocanu H, Mocanu AI, Drăgoi AM and Rădulescu M: Long-term histological results of ossicular chain reconstruction using bioceramic implants. Exp Ther Med. 21(260)2021.PubMed/NCBI View Article : Google Scholar

23 

Caro JJ, Salas M and Goss G: Anemia as independent prognostic factor for survival in patients with cancer: A systemic, quantitative review. Cancer. 91:2214–2221. 2001.PubMed/NCBI

24 

Danan D, Shonka DC Jr, Selman Y, Chow Z, Smolkin ME and Jameson MJ: Prognostic value of albumin in patients with head and neck cancer. Laryngoscope. 126:1567–1571. 2016.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Vulcu Cordunianu A, Ganea G, Cordunianu MA and Cochior D: Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report. Exp Ther Med 23: 195, 2022.
APA
Vulcu Cordunianu, A., Ganea, G., Cordunianu, M.A., & Cochior, D. (2022). Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report. Experimental and Therapeutic Medicine, 23, 195. https://doi.org/10.3892/etm.2022.11118
MLA
Vulcu Cordunianu, A., Ganea, G., Cordunianu, M. A., Cochior, D."Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report". Experimental and Therapeutic Medicine 23.3 (2022): 195.
Chicago
Vulcu Cordunianu, A., Ganea, G., Cordunianu, M. A., Cochior, D."Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report". Experimental and Therapeutic Medicine 23, no. 3 (2022): 195. https://doi.org/10.3892/etm.2022.11118
Copy and paste a formatted citation
x
Spandidos Publications style
Vulcu Cordunianu A, Ganea G, Cordunianu MA and Cochior D: Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report. Exp Ther Med 23: 195, 2022.
APA
Vulcu Cordunianu, A., Ganea, G., Cordunianu, M.A., & Cochior, D. (2022). Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report. Experimental and Therapeutic Medicine, 23, 195. https://doi.org/10.3892/etm.2022.11118
MLA
Vulcu Cordunianu, A., Ganea, G., Cordunianu, M. A., Cochior, D."Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report". Experimental and Therapeutic Medicine 23.3 (2022): 195.
Chicago
Vulcu Cordunianu, A., Ganea, G., Cordunianu, M. A., Cochior, D."Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report". Experimental and Therapeutic Medicine 23, no. 3 (2022): 195. https://doi.org/10.3892/etm.2022.11118
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team