Journal Articles

Article Open Access

LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway

Yihui Xu, Hubo Shi, Min Wang, Ping Huang, Mingjie Xu, Shuyi Han, Huanjie Li, Yunshan Wang

Article Number: 247 Published online on: 28 January 2022
Article Open Access

Long non‑coding RNA HCG22 inhibits the proliferation, invasion and migration of oral squamous cell carcinoma cells by downregulating miR‑425‑5p expression

Yating Fu, Ying Liu, Aheli Nasiroula, Qichao Wang, Xinhua Cao

Article Number: 246 Published online on: 28 January 2022
Correction Open Access

[Corrigendum] RNA‑binding protein CELF2 inhibits breast cancer cell invasion and angiogenesis by downregulating NFATc1

Limin Zhou, Xiju Xie

Article Number: 245 Published online on: 27 January 2022
Article Open Access

Circular RNA, hsa_circRNA_102049, promotes colorectal cancer cell migration and invasion via binding and suppressing miRNA‑455‑3p

Yuandong Zhu, Jianjion Li, Haiyuan Liu, Zhengming Song, Qinghua Yang, Chengdong Lu, Wenbin Chen

Article Number: 244 Published online on: 27 January 2022
Article Open Access

MicroRNA‑4722‑5p and microRNA‑615‑3p serve as potential biomarkers for Alzheimer's disease

Yan Liu, Yuhao Xu, Ming Yu

Article Number: 241 Published online on: 26 January 2022
Article Open Access

Vitamin D3 promotes autophagy in THP‑1 cells infected with Mycobacterium tuberculosis

Yiming Wu, Xue Lin, Fuyang Song, Di Xue, Yujiong Wang

Article Number: 240 Published online on: 25 January 2022
Article Open Access

Combined treatment with niclosamide ethanolamine and artemether combination improves type 1 diabetes via the targeting of liver mitochondria

Wenci Weng, Honghong Liu, Zhijian Sun, Peng Zhou, Xuewen Yu, Mumin Shao, Pengxun Han, Huili Sun

Article Number: 239 Published online on: 25 January 2022
Article Open Access

Total astragalosides decrease apoptosis and pyroptosis by inhibiting enterovirus 71 replication in gastric epithelial cells

Xiaoyan Zhang, Jinfang Hao, Chenxi Sun, Jianping Du, Qian Han, Qingshan Li

Article Number: 237 Published online on: 24 January 2022
Article Open Access
Article Open Access

Docosahexaenoic acid improves altered mineralization proteins, the decreased quality of hydroxyapatite crystals and suppresses oxidative stress induced by high glucose

Saúl Ernesto Cifuentes‑Mendiola, Leticia Moreno‑Fierros, Patricia González‑Alva, Ana Lilia García‑Hernández

Article Number: 235 Published online on: 21 January 2022
Article Open Access

Eyelid carcinomas: Tumor aggressiveness tendencies for smokers compared to non‑smokers

Razvan Mercut, Irina Maria Mercut, Adina Dorina Glodeanu, Mihaela Ionescu, Adina Turcu, Alin Stefanescu‑Dima, Marius Eugen Ciurea

Article Number: 234 Published online on: 21 January 2022
Retraction Open Access

[Retracted] MicroRNA‑124‑3p inhibits cell growth and metastasis in cervical cancer by targeting IGF2BP1

Ping Wang, Li Zhang, Junhui Zhang, Gangshu Xu

Article Number: 233 Published online on: 20 January 2022
Article Open Access

Combination treatment with sorafenib and wh‑4 additively suppresses the proliferation of liver cancer cells

Su-Hong Chen, Dan-Dan Xu, Peng-Jun Zhou, Yao Wang, Qiu-Ying Liu, Zhe Ren, Zhong Liu, Xia Wang, Hui-Qing Huang, Xue Xue, Ying Wang, Yi-Fei Wang

Article Number: 232 Published online on: 20 January 2022
Article Open Access

miR‑146b‑5p promotes colorectal cancer progression by targeting TRAF6

Liangpan Shi, Yibin Su, Zhihua Zheng, Jinyu Qi, Weidong Wang, Cunchuan Wang

Article Number: 231 Published online on: 20 January 2022
Article Open Access

MicroRNA‑21‑5p acts via the PTEN/Akt/FOXO3a signaling pathway to prevent cardiomyocyte injury caused by high glucose/high fat conditions

Ying Han, Xiaoqin Cai, Min Pan, Jin Gong, Wenqin Cai, Dan Lu, Changsheng Xu

Article Number: 230 Published online on: 18 January 2022
Article Open Access

Butorphanol reduces the neuronal inflammatory response and apoptosis via inhibition of p38/JNK/ATF2/p53 signaling

Yingsi Huang, Shuhua Li, Huaxin Chen, Long Feng, Weixiu Yuan, Tao Han

Article Number: 229 Published online on: 18 January 2022
Article Open Access

Study on the value of antibiotic‑resistant gene detection in Helicobacter pylori in China

Jinfeng Dai, Jing Zhao, Liqi Mao, Yue Hu, Bin Lv

Article Number: 228 Published online on: 18 January 2022
Article Open Access

Biological activity of a vascular endothelial cell‑hydroxyapatite orbital implant complex: An experimental study

Weiqi Wu, Hao Luo, Dan Wu, Menglin Shi, Jinhai Yu, Hongfei Liao

Article Number: 227 Published online on: 18 January 2022
Article Open Access

HMBOX1 attenuates LPS‑induced periodontal ligament stem cell injury by inhibiting CXCL10 expression through the NF‑κB signaling pathway

Minyuan Nie, Heng Li, Puhe Liu, Ping Dang

Article Number: 224 Published online on: 17 January 2022
Article

Effect of intravenous thrombolysis combined with mild hypothermia on the levels of IL‑1β, IL‑6, ICAM‑1 and MMP‑2 in patients with acute cerebral infarction and clinical significance

Chaosheng Li, Lingling Hu, Jilai Zhao, Meiqi Di, Changyan Fan, Likun Han, Xuying Zhu

Article Number: 223 Published online on: 17 January 2022
Article Open Access

Metformin reduces chondrocyte pyroptosis in an osteoarthritis mouse model by inhibiting NLRP3 inflammasome activation

Jiangbo Yan, Dong Ding, Gangning Feng, Yong Yang, Yong Zhou, Long Ma, Haohui Guo, Zhidong Lu, Qunhua Jin

Article Number: 222 Published online on: 17 January 2022
Article

Impact of metabolic disorders on endometrial receptivity in patients with polycystic ovary syndrome

Can Wang, Yang-Xing Wen, Qing-Yun Mai

Article Number: 221 Published online on: 14 January 2022
Article

Pediatric esophageal stenoses: Challenges and new surgical device promoting tension‑free esophageal anastomosis

Dan Alexandru Iozsa, Radu-Iulian Spătaru, Luminita Florentina Tomescu, Ovidiu Stiru, Florentina Gherghiceanu, Florentina Furtunescu, Daniel Radavoi, Nicolae Bacalbasa, Irina Balescu, Adrian Tulin

Article Number: 220 Published online on: 14 January 2022
Review Open Access

Benefits and adverse events of melatonin use in the elderly (Review)

Lucreția Anghel, Liliana Baroiu, Corina Rișcă Popazu, Diana Pătraș, Silvia Fotea, Alexandru Nechifor, Anamaria Ciubara, Luiza Nechita, Carmina Liana Mușat, Ioana Anca Stefanopol, Alin Laurențiu Tatu, Alexandru Bogdan Ciubara

Article Number: 219 Published online on: 14 January 2022
Case Report

Pituitary adenoma apoplexy in pregnancy: Case report and literature review

Lucian Gheorghe Pop, Aurora Ilian, Tiberiu Georgescu, Nicolae Bacalbasa, Irina Balescu, Oana Daniela Toader

Article Number: 218 Published online on: 14 January 2022
Article

Identification of key pathways and genes in vestibular schwannoma using bioinformatics analysis

Bo Wu, Gaojing Dou, Yuan Zhang, Jing Wang, Xinhui Wang, Shanshan Jiang, Sheng Zhong, Junan Ren, Zhiyun Zhang, Jiahui Li, Chunjia Sheng, Gang Zhao, Liyan Zhao

Article Number: 217 Published online on: 13 January 2022
Article Open Access

Telmisartan inhibits bladder smooth muscle fibrosis in neurogenic bladder rats

Qian Liu, Ruoyi Wang, Nan Ma, Chuntian Wang, Weixiu Chen

Article Number: 216 Published online on: 11 January 2022
Article Open Access

Efficiency of platelet‑rich plasma therapy for healing sports injuries in young athletes

Alexandru Herdea, Alexandra Struta, Răzvan Petru Derihaci, Alexandru Ulici, Adrian Costache, Florentina Furtunescu, Alexandra Toma, Adham Charkaoui

Article Number: 215 Published online on: 11 January 2022
Case Report Open Access

Ophthalmic herpes zoster with severe complications in an immunocompromised patient: A case report and review of the literature

Gabriela Mariana Iancu, Dan Mircea Stănilă, Remus Călin Cipăian, Maria Rotaru

Article Number: 214 Published online on: 11 January 2022
Article Open Access

Diagnostic use of computerized axiography in TMJ disc displacements

Daniel Talmaceanu, Nicolae Bolog, Daniel Leucuta, Ioan Andrei Tig, Smaranda Buduru

Article Number: 213 Published online on: 11 January 2022
Article Open Access

Construction of a rabbit model with vinorelbine administration via peripherally inserted central catheter and dynamic monitoring of changes in phlebitis and thrombosis

Liquan Huang, Guiyuan Chen, Qinghua Hu, Bo Hu, Louying Zhu, Luyan Fang

Article Number: 212 Published online on: 11 January 2022
Correction Open Access

[Corrigendum] Metoprolol and bisoprolol ameliorate hypertrophy of neonatal rat cardiomyocytes induced by high glucose via the PKC/NF‑κB/c‑fos signaling pathway

Min Wang, Qingbo Lv, Liding Zhao, Yao Wang, Yi Luan, Zhengwei Li, Guosheng Fu, Wenbin Zhang

Article Number: 211 Published online on: 10 January 2022
Article Open Access

Low‑field magnetic stimulation improved cuprizone‑induced depression‑like symptoms and demyelination in female mice

Ali Mooshekhian, Thaisa Sandini, Zelan Wei, Rebekah Van Bruggen, Haibo Li, Xin-Min Li, Yanbo Zhang

Article Number: 210 Published online on: 07 January 2022
Article Open Access

Harmine reinforces the effects of regorafenib on suppressing cell proliferation and inducing apoptosis in liver cancer cells

Zi-Yi Chen, Jie Li, Shu-Di Zhu, Zhi-Di Li, Jia-Lin Yu, Jie Wu, Chong Zhang, Ling-Hui Zeng

Article Number: 209 Published online on: 07 January 2022
Article Open Access

The anti‑inflammation effect of strontium ranelate on rat chondrocytes with or without IL‑1β in vitro

Hao Yu, Yan Liu, Xiangwen Yang, Jiajing He, Qun Zhong, Xiaojing Guo

Article Number: 208 Published online on: 07 January 2022
Article Open Access

Col9a2 gene deletion accelerates the degeneration of intervertebral discs

Huihui Xu, Rui Dong, Qinghe Zeng, Liang Fang, Qinwen Ge, Chenjie Xia, Peng Zhang, Shuaijie Lv, Zhen Zou, Pinger Wang, Ju Li, Hongfeng Ruan, Songfeng Hu, Chengliang Wu, Hongting Jin, Peijian Tong

Article Number: 207 Published online on: 07 January 2022
Article Open Access

Effects of chronic folate deficiency and sex differences on depression‑like behavior in mice

Wanxiao Sun, Qiting Qing, Xu Cheng, Jing Chen, Ningning Yu, Liyuan Zhu, Mei Zhao

Article Number: 206 Published online on: 07 January 2022
Article Open Access

Wogonin reduces cardiomyocyte apoptosis from mitochondrial release of cytochrome c to improve doxorubicin‑induced cardiotoxicity

Yunjie Wei, Junhao Zhao, Jian Xiong, Jingjing Chai, Xi Yang, Junfeng Wang, Jiajuan Chen, Jing Wang

Article Number: 205 Published online on: 07 January 2022
Article Open Access

MAGEA6 positively regulates MSMO1 and promotes the migration and invasion of oesophageal cancer cells

Manyu Liu, Jintao Li, Yangjunqi Wang, Maliha Ghaffar, Yishu Yang, Minglian Wang, Changshuo Li

Article Number: 204 Published online on: 07 January 2022
Article Open Access

Long non‑coding RNA TUG1 knockdown repressed the viability, migration and differentiation of osteoblasts by sponging miR‑214

Zhitao Yao, Wei An, Adili Moming, Maimaitituxun Tuerdi

Article Number: 203 Published online on: 07 January 2022
Article Open Access

An original method of simulating the articular cartilage in the context of in vitro biomechanical studies investigating the proximal femur

Teodor Stefan Gheorghevici, Eugen Carata, Paul-Dan Sirbu, Ovidiu Alexa, Manuela-Gabi Poroh, Alexandru Filip, Norin Forna, Bogdan Puha

Article Number: 202 Published online on: 05 January 2022
Review Open Access

Update on the etiopathogenesis of psoriasis (Review)

Daciana Elena Branisteanu, Catalina Cojocaru, Roxana Diaconu, Elena Andrese Porumb, Anisia Iuliana Alexa, Alin Codrut Nicolescu, Ilarie Brihan, Camelia Margareta Bogdanici, George Branisteanu, Andreea Dimitriu, Mihail Zemba, Nicoleta Anton, Mihaela Paula Toader, Adrian Grechin, Daniel Constantin Branisteanu

Article Number: 201 Published online on: 05 January 2022
Article Open Access

Emergency department point‑of‑care biomarkers and day 90 functional outcome in spontaneous intracerebral hemorrhage: A single‑center pilot study

Eugenia-Maria Mureșan, Adela Golea, Ștefan Cristian Vesa, Manuela Lenghel, Csaba Csutak, Lăcrămioara Perju‑Dumbravă

Article Number: 200 Published online on: 05 January 2022
Article

Influence of the microenvironment dynamics on extracellular matrix evolution under hypoxic ischemic conditions in the myocardium

Zenaida Ceauşu, Manuela Popa, Bogdan Socea, Gabriel Petre Gorecki, Mariana Costache, Mihai Ceauşu

Article Number: 199 Published online on: 05 January 2022
Article Open Access

Treatment of C1.1 (AO‑41) tibial plateau fracture: A finite element analysis of single medial, lateral and dual plating

Norin Forna, Florin Munteanu, Sînziana Anca Butnaru Moldoveanu, Liliana Savin, Paul Dan Sîrbu, Bogdan Puha

Article Number: 198 Published online on: 05 January 2022
Review Open Access

Role of antioxidants and oxidative stress in the evolution of acute pancreatitis (Review)

Vlad Pădureanu, Dan Nicolae Florescu, Rodica Pădureanu, Alice Elena Ghenea, Dan Ionuț Gheonea, Carmen Nicoleta Oancea

Article Number: 197 Published online on: 05 January 2022
Article Open Access

Minimally invasive treatment and internal fixation vs. extended lateral approach in calcaneus fractures of thalamic interest

Adrian Cursaru, Bogdan Crețu, Bogdan Șerban, Sergiu Iordache, Mihnea Popa, Catalin Gabriel Smarandache, Carmen Orban, Cătălin Cîrstoiu

Article Number: 196 Published online on: 05 January 2022
Case Report Open Access

Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report

Alina-Georgiana Vulcu Cordunianu, Gabriel Ganea, Mihai Alexandru Cordunianu, Daniel Cochior

Article Number: 195 Published online on: 05 January 2022
Article Open Access

lncRNA Kcnq1ot1 promotes bone formation by inhibiting miR‑98‑5p/Tbx5 axis in MC3T3‑E1 cells

Furong Wang, Fucai Zhang, Feng Zheng

Article Number: 194 Published online on: 05 January 2022
Article Open Access

Lidocaine relieves murine allergic rhinitis by regulating the NF‑κB and p38 MAPK pathways

Jing Xiang, Zhen Yang, Qiang Zhou

Article Number: 193 Published online on: 05 January 2022
Review Open Access

Treatment for transverse patella fractures with minimally invasive techniques (Review)

Xiang-Yu Ma, Bing Liu, Da-Peng Zhou, Liang-Bi Xiang

Article Number: 192 Published online on: 05 January 2022
Review Open Access

Insulin‑like growth factor‑1: A potential target for bronchopulmonary dysplasia treatment (Review)

Shujian Zhang, Xue Luan, Huiwen Li, Zhengyong Jin

Article Number: 191 Published online on: 05 January 2022
Correction Open Access

[Corrigendum] Moxibustion improves ovarian function based on the regulation of the androgen balance

Xun Jin, Jie Cheng, Jie Shen, Xing Lv, Qian Li, Yanyun Mu, Hua Bai, Yan Liu, Youbing Xia

Article Number: 190 Published online on: 04 January 2022
Case Report Open Access

From chronic pruritus to neuroendocrine tumor: A case report

Alexandr Ceasovschih, Giorgiana Voloc, Victorița Șorodoc, Dan Vâță, Cristian-Dumitru Lupașcu, Cristina Preda, Cătălina Lionte, Alexandra Stoica, Oana Sîrbu, Elena-Daniela Grigorescu, Raluca Ecaterina Haliga, Adorata Elena Coman, Cristina Bologa, Luminița Gina Vâță, Ovidiu Rusalim Petriș, Gabriela Puha, Gabriela Dumitrescu, Mihai Constantin, Laurențiu Șorodoc

Article Number: 189 Published online on: 04 January 2022
Journal Cover

March-2022
Volume 23 Issue 3

Print ISSN: 1792-0981
Online ISSN: 1792-1015

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