Imaging analysis of the malignant transformation of bile duct hamartomas in the liver: A case report and literature review

Yuan,Yuan; Fu,Gang; Wan,Feng; Chen,Xu-Lei; Feng,Jun

doi:10.3892/etm.2022.11358

Imaging analysis of the malignant transformation of bile duct hamartomas in the liver: A case report and literature review

Authors:
- Yuan Yuan
- Gang Fu
- Feng Wan
- Xu-Lei Chen
- Jun Feng
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Affiliations: Department of Ultrasound, The Second Hospital of Wuxi Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214002, P.R. China, Department of Pathology, The Second Hospital of Wuxi Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214002, P.R. China
Published online on: May 9, 2022 https://doi.org/10.3892/etm.2022.11358
Article Number: 431
Copyright : © Yuan et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

Bile duct hamartoma in the liver (LBDH) is relatively rare among the hepatic space‑occupying lesions that occur in adults, and the malignant transformation of LBDH is even rarer. In the present case report, a 63‑year‑old male was found to have two space‑occupying lesions in the right lobe of the liver upon ultrasound examination. Enhanced computed tomography (CT) suggested benign hepatic haemangioma, and contrast‑enhanced ultrasonography (CEUS) suggested well‑differentiated hepatocellular carcinoma. The final pathology results revealed the malignant transformation of LBDH into well‑differentiated intrahepatic cholangiocarcinoma. Improved recognition of this type of rare disease can be obtained by radiographic analysis of this case. These findings contribute to a better understanding of the enhanced development pattern of this disease on contrast‑enhanced CT, as well as on CEUS.

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