|
1
|
Cui Y, Wang Y, Zhao D, Feng X, Zhang L and
Liu C: Loganin prevents BV-2 microglia cells from Abeta1-42
-induced inflammation via regulating TLR4/TRAF6/NF-κB axis. Cell
Biol Int. 42:1632–1642. 2018.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Lane CA, Hardy J and Schott JM:
Alzheimer's disease. Eur J Neurol. 25:59–70. 2018.PubMed/NCBI View Article : Google Scholar
|
|
3
|
De-Paula VJ, Radanovic M, Diniz BS and
Forlenza OV: Alzheimer's disease. Subcell Biochem. 65:329–352.
2012.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Calsolaro V and Edison P:
Neuroinflammation in Alzheimer's disease: Current evidence and
future directions. Alzheimers Dement. 12:719–732. 2016.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Varnum MM and Ikezu T: The classification
of microglial activation phenotypes on neurodegeneration and
regeneration in Alzheimer's disease brain. Arch Immunol Ther Exp
(Warsz). 60:251–266. 2012.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Unger MS, Li E, Scharnagl L, Poupardin R,
Altendorfer B, Mrowetz H, Hutter-Paier B, Weiger TM, Heneka MT,
Attems J and Aigner L: CD8(+) T-cells infiltrate Alzheimer's
disease brains and regulate neuronal- and synapse-related gene
expression in APP-PS1 transgenic mice. Brain Behav Immun. 89:67–86.
2020.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Mosher KI and Wyss-Coray T: Microglial
dysfunction in brain aging and Alzheimer's disease. Biochem
Pharmacol. 88:594–604. 2014.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Kang SY, Jung HW, Lee MY, Lee HW, Chae SW
and Park YK: Effect of the semen extract of Cuscuta chinensis on
inflammatory responses in LPS-stimulated BV-2 microglia. Chin J Nat
Med. 12:573–581. 2014.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Namekata K, Kimura A, Kawamura K, Harada C
and Harada T: Dock GEFs and their therapeutic potential:
Neuroprotection and axon regeneration. Prog Retin Eye Res. 43:1–16.
2014.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Kearney CJ, Randall KL and Oliaro J: DOCK8
regulates signal transduction events to control immunity. Cell Mol
Immunol. 14:406–411. 2017.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Namekata K, Guo X, Kimura A, Arai N,
Harada C and Harada T: DOCK8 is expressed in microglia, and it
regulates microglial activity during neurodegeneration in murine
disease models. J Biol Chem. 294:13421–13433. 2019.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Biggs CM, Keles S and Chatila TA: DOCK8
deficiency: Insights into pathophysiology, clinical features and
management. Clin Immunol. 181:75–82. 2017.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Moon MY, Kim HJ, Li Y, Kim JG, Jeon YJ,
Won HY, Kim JS, Kwon HY, Choi IG, Ro E, et al: Involvement of small
GTPase RhoA in the regulation of superoxide production in BV2 cells
in response to fibrillar Abeta peptides. Cell Signal. 25:1861–1869.
2013.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Cimino PJ, Yang Y, Li X, Hemingway JF,
Cherne MK, Khademi SB, Fukui Y, Montine KS, Montine TJ and Keene
CD: Ablation of the microglial protein DOCK2 reduces amyloid burden
in a mouse model of Alzheimer's disease. Exp Mol Pathol.
94:366–371. 2013.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Jiang CQ, Ma LL, Lv ZD, Feng F, Chen Z and
Liu ZD: Polydatin induces apoptosis and autophagy via STAT3
signaling in human osteosarcoma MG-63 cells. J Nat Med. 74:533–544.
2020.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Jian M, Kwan JS, Bunting M, Ng RC and Chan
KH: Adiponectin suppresses amyloid-β oligomer (AβO)-induced
inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling
pathway. J Neuroinflammation. 16(110)2019.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Latta CH, Brothers HM and Wilcock DM:
Neuroinflammation in Alzheimer's disease; A source of heterogeneity
and target for personalized therapy. Neuroscience. 302:103–111.
2015.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Heneka MT, Carson MJ, El Khoury J,
Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T,
Vitorica J, Ransohoff RM, et al: Neuroinflammation in Alzheimer's
disease. Lancet Neurol. 14:388–405. 2015.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Heppner FL, Ransohoff RM and Becher B:
Immune attack: The role of inflammation in Alzheimer disease. Nat
Rev Neurosci. 16:358–372. 2015.PubMed/NCBI View
Article : Google Scholar
|
|
21
|
Imai Y, Ibata I, Ito D, Ohsawa K and
Kohsaka S: A novel gene iba1 in the major histocompatibility
complex class III region encoding an EF hand protein expressed in a
monocytic lineage. Biochem Biophys Res Commun. 224:855–862.
1996.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Maneu V, Noailles A, Megias J,
Gómez-Vicente V, Carpena N, Gil ML, Gozalbo D and Cuenca N: Retinal
microglia are activated by systemic fungal infection. Invest
Ophthalmol Vis Sci. 55:3578–3585. 2014.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Shi FJ, Xie H, Zhang CY, Qin HF, Zeng XW,
Lou H, Zhang L, Xu GT, Zhang JF and Xu GX: Is Iba-1 protein
expression a sensitive marker for microglia activation in
experimental diabetic retinopathy? Int J Ophthalmol. 14:200–208.
2021.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Muhammad T, Ikram M, Ullah R, Rehman SU
and Kim MO: Hesperetin, a citrus flavonoid, attenuates LPS-induced
neuroinflammation, apoptosis and memory impairments by modulating
TLR4/NF-κB signaling. Nutrients. 11(648)2019.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Park T, Chen H, Kevala K, Lee JW and Kim
HY: N-Docosahexaenoylethanolamine ameliorates LPS-induced
neuroinflammation via cAMP/PKA-dependent signaling. J
Neuroinflammation. 13(284)2016.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Zhu SH, Liu BQ, Hao MJ, Fan YX, Qian C,
Teng P, Zhou XW, Hu L, Liu WT, Yuan ZL and Li QP: Paeoniflorin
suppressed high glucose-induced retinal microglia MMP-9 expression
and inflammatory response via inhibition of TLR4/NF-κB pathway
through upregulation of SOCS3 in diabetic retinopathy.
Inflammation. 40:1475–1486. 2017.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Hopperton KE, Mohammad D, Trepanier MO,
Giuliano V and Bazinet RP: Markers of microglia in post-mortem
brain samples from patients with Alzheimer's disease: A systematic
review. Mol Psychiatry. 23:177–198. 2018.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Dobryakova YV, Kasianov A, Zaichenko MI,
Stepanichev MY, Chesnokova EA, Kolosov PM, Markevich VA and
Bolshakov AP: Intracerebroventricular administration of
(192)IgG-Saporin alters expression of microglia-associated genes in
the dorsal but not ventral hippocampus. Front Mol Neurosci.
10(429)2017.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Aydin SE, Kilic SS, Aytekin C, Kumar A,
Porras O, Kainulainen L, Kostyuchenko L, Genel F, Kütükcüler N,
Karaca N, et al: DOCK8 deficiency: Clinical and immunological
phenotype and treatment options-a review of 136 patients. J Clin
Immunol. 35:189–198. 2015.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Zhang Z, Bao Y, Zhou L, Ye Y, Fu W and Sun
C: DOCK8 Serves as a prognostic biomarker and is related to immune
infiltration in patients with HPV positive head and neck squamous
cell carcinoma. Cancer Control.
28(10732748211011951)2021.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Xu X, Han L, Zhao G, Xue S, Gao Y, Xiao J,
Zhang S, Chen P, Wu ZY, Ding J, et al: LRCH1 interferes with
DOCK8-Cdc42-induced T cell migration and ameliorates experimental
autoimmune encephalomyelitis. J Exp Med. 214:209–226.
2017.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Miyamoto Y, Torii T, Kawahara K, Tanoue A
and Yamauchi J: Dock8 interacts with Nck1 in mediating Schwann cell
precursor migration. Biochem Biophys Rep. 6:113–123.
2016.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Ham H, Guerrier S, Kim J, Schoon RA,
Anderson EL, Hamann MJ, Lou Z and Billadeau DD: Dedicator of
cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome
protein to regulate NK cell cytotoxicity. J Immunol. 190:3661–3669.
2013.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Hillmer EJ, Zhang H, Li HS and Watowich
SS: STAT3 signaling in immunity. Cytokine Growth Factor Rev.
31:1–15. 2016.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Takeda K, Kaisho T, Yoshida N, Takeda J,
Kishimoto T and Akira S: Stat3 activation is responsible for
IL-6-dependent T cell proliferation through preventing apoptosis:
Generation and characterization of T cell-specific Stat3-deficient
mice. J Immunol. 161:4652–4660. 1998.PubMed/NCBI
|
|
36
|
Kortylewski M and Yu H: Role of Stat3 in
suppressing anti-tumor immunity. Curr Opin Immunol. 20:228–233.
2008.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Egwuagu CE: STAT3 in CD4+ T
helper cell differentiation and inflammatory diseases. Cytokine.
47:149–156. 2009.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Keles S, Charbonnier LM, Kabaleeswaran V,
Reisli I, Genel F, Gulez N, Al-Herz W, Ramesh N, Perez-Atayde A,
Karaca NE, et al: Dedicator of cytokinesis 8 regulates signal
transducer and activator of transcription 3 activation and promotes
TH17 cell differentiation. J Allergy Clin Immunol. 138:1384–1394
e1382. 2016.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Zhu H, Jian Z, Zhong Y, Ye Y, Zhang Y, Hu
X, Pu B, Gu L and Xiong X: Janus kinase inhibition ameliorates
ischemic stroke injury and neuroinflammation through reducing NLRP3
inflammasome activation via JAK2/STAT3 pathway inhibition. Front
Immunol. 12(714943)2021.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Dai R, Jiang Q, Zhou Y, Lin R, Lin H,
Zhang Y, Zhang J and Gao X: Lnc-STYK1-2 regulates bladder cancer
cell proliferation, migration, and invasion by targeting
miR-146b-5p expression and AKT/STAT3/NF-kB signaling. Cancer Cell
Int. 21(408)2021.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Pal M, Bao W, Wang R, Liu Y, An X,
Mitchell WB, Lobo CA, Minniti C, Shi PA, Manwani D, et al:
Hemolysis inhibits humoral B-cell responses and modulates
alloimmunization risk in patients with sickle cell disease. Blood.
137:269–280. 2021.PubMed/NCBI View Article : Google Scholar
|
