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Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy

  • Authors:
    • Yi Sun
    • Jing Zhu
    • Juan Guo
    • Yuanxu He
    • Zhanfeng Wang
  • View Affiliations / Copyright

    Affiliations: Department of Ophthalmology, The Third People's Hospital of Chengdu, Chengdu, Sichuan 610031, P.R. China
    Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 280
    |
    Published online on: April 25, 2023
       https://doi.org/10.3892/etm.2023.11980
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Abstract

The Wuerzburg bleb classification system (WBCS) is an established tool for evaluating filtering blebs, while anterior segment optical coherence tomography (ASOCT) provides detailed information on inner bleb structure. The present study aimed to investigate the clinical value of ASOCT‑assisted WBCS following trabeculectomy (TRAB). The present prospective, observational study included eyes that underwent TRAB. Bleb assessments using the WBCS were based on the image acquired by ASOCT. The WBCS scores were assessed at postoperative week 2 and postoperative month (POM) 1, 2, 3, 6 and 12. The surgical outcomes at 1 year were determined as success or failure. Spearman's analysis explored the correlation of WBCS scores with intraocular pressure (IOP) and surgical outcome. A total of 32 eyes from 32 patients were included in the present study. The WBCS total score significantly correlated with IOP at POM 1, 2, 3, 6 and 12 (P<0.05). For single parameters, microcysts demonstrated a good correlation with IOP at POM 1, 2, 3, 6 and 12 (P<0.05). The WBCS total score correlated well with surgical outcome at POM 2, 3, 6 and 12 (P≤0.005). Microcysts, vascularity and encapsulation significantly correlated with surgical outcomes (P<0.05). The results of the present study suggest that ASOCT‑assisted WBCS is a simple and effective measurement system for blebs after TRAB in clinical practice, which correlates well with IOP and surgical outcomes. Blebs with a higher WBCS total score and microcysts score in the early postoperative period, such as at POM 2 and 3, are less likely to have surgical failure in the long term.
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Copy and paste a formatted citation
Spandidos Publications style
Sun Y, Zhu J, Guo J, He Y and Wang Z: Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy. Exp Ther Med 25: 280, 2023.
APA
Sun, Y., Zhu, J., Guo, J., He, Y., & Wang, Z. (2023). Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy. Experimental and Therapeutic Medicine, 25, 280. https://doi.org/10.3892/etm.2023.11980
MLA
Sun, Y., Zhu, J., Guo, J., He, Y., Wang, Z."Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy". Experimental and Therapeutic Medicine 25.6 (2023): 280.
Chicago
Sun, Y., Zhu, J., Guo, J., He, Y., Wang, Z."Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy". Experimental and Therapeutic Medicine 25, no. 6 (2023): 280. https://doi.org/10.3892/etm.2023.11980
Copy and paste a formatted citation
x
Spandidos Publications style
Sun Y, Zhu J, Guo J, He Y and Wang Z: Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy. Exp Ther Med 25: 280, 2023.
APA
Sun, Y., Zhu, J., Guo, J., He, Y., & Wang, Z. (2023). Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy. Experimental and Therapeutic Medicine, 25, 280. https://doi.org/10.3892/etm.2023.11980
MLA
Sun, Y., Zhu, J., Guo, J., He, Y., Wang, Z."Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy". Experimental and Therapeutic Medicine 25.6 (2023): 280.
Chicago
Sun, Y., Zhu, J., Guo, J., He, Y., Wang, Z."Clinical value of anterior segment optical coherence tomography‑assisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy". Experimental and Therapeutic Medicine 25, no. 6 (2023): 280. https://doi.org/10.3892/etm.2023.11980
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