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Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases

  • Authors:
    • Liang Jing
    • Xi Peng
    • Dayong Li
    • Yusen Qin
    • Yaqin Song
    • Wei Zhu
  • View Affiliations / Copyright

    Affiliations: Department of Emergency‑Critical Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430032, P.R. China, Department of Internal Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430032, P.R. China
    Copyright: © Jing et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 476
    |
    Published online on: August 22, 2023
       https://doi.org/10.3892/etm.2023.12175
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Abstract

Inhalation of acid fumes and aspiration of liquid substances or gastric contents may not initiate dyspnea within several hours after exposure but may result in delayed onset of alveolar edema. The present report presents three cases of inhalation or aspiration of chemical substances that resulted in acute respiratory distress syndrome (ARDS). Due to different underlying reasons, three patients developed ARDS resulting from chemical pneumonitis and pulmonary infection. From patients with dyspnea, dry rales could be heard in both lungs, with <92% percutaneous oxygen saturation at room air. All patients were treated using a high‑flow nasal cannula and sivelestat sodium. Oxygenation gradually improved and the patients were discharged without adverse events. These cases suggest that early treatment with sivelestat sodium may improve the clinical outcomes of patients with ARDS.
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Copy and paste a formatted citation
Spandidos Publications style
Jing L, Peng X, Li D, Qin Y, Song Y and Zhu W: Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases. Exp Ther Med 26: 476, 2023.
APA
Jing, L., Peng, X., Li, D., Qin, Y., Song, Y., & Zhu, W. (2023). Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases. Experimental and Therapeutic Medicine, 26, 476. https://doi.org/10.3892/etm.2023.12175
MLA
Jing, L., Peng, X., Li, D., Qin, Y., Song, Y., Zhu, W."Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases". Experimental and Therapeutic Medicine 26.4 (2023): 476.
Chicago
Jing, L., Peng, X., Li, D., Qin, Y., Song, Y., Zhu, W."Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases". Experimental and Therapeutic Medicine 26, no. 4 (2023): 476. https://doi.org/10.3892/etm.2023.12175
Copy and paste a formatted citation
x
Spandidos Publications style
Jing L, Peng X, Li D, Qin Y, Song Y and Zhu W: Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases. Exp Ther Med 26: 476, 2023.
APA
Jing, L., Peng, X., Li, D., Qin, Y., Song, Y., & Zhu, W. (2023). Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases. Experimental and Therapeutic Medicine, 26, 476. https://doi.org/10.3892/etm.2023.12175
MLA
Jing, L., Peng, X., Li, D., Qin, Y., Song, Y., Zhu, W."Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases". Experimental and Therapeutic Medicine 26.4 (2023): 476.
Chicago
Jing, L., Peng, X., Li, D., Qin, Y., Song, Y., Zhu, W."Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases". Experimental and Therapeutic Medicine 26, no. 4 (2023): 476. https://doi.org/10.3892/etm.2023.12175
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