Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
May-2024 Volume 27 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2024 Volume 27 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand

  • Authors:
    • Jing'en Sun
    • Siman Su
    • Songsong Jiao
    • Gang Li
    • Zhi Zhang
    • Weihua Lin
    • Shuyao Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Burns and Plastic Surgery, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, Guangdong 510220, P.R. China, Department of Pharmacology, Shantou University Medical College, Shantou, Guangdong 515041, P.R. China, Department of Orthopedics, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, Guangdong 510220, P.R. China, Department of Pharmacy, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, Guangdong 510220, P.R. China
    Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 238
    |
    Published online on: March 27, 2024
       https://doi.org/10.3892/etm.2024.12526
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of the present study was to investigate the possibility of reducing the damage to the donor site while preserving the functional recovery of the dorsum of the hand following burn injury. An attempt was made to analyze the effect of a phased surgery approach on inflammatory indicators. A two‑phase treatment was administered on a total of 64 patients with deep second‑degree burns on the dorsum of the hand who were admitted to Guangzhou Red Cross Hospital between January 2020 and March 2023. During phase I treatment, the wounds were covered with xenogeneic (porcine) skin, followed by the application of autologous thin intermediate thickness skin grafts for wound repair in phase II treatment 1 week later. The surgical results, complications, patient satisfaction and inflammatory response indicators were then analyzed. The mean wound healing time of these patients was found to be 21.94 days without complications. The mean survival rate was 98.66%, and the overall satisfaction score of the patients was high. Finally, the white blood cell, C‑reactive protein and IL‑6 levels of these patients were continuously decreased 2 days preoperatively and 2 days postoperatively in phase I, and 2 days preoperatively and 2 days postoperatively in phase II. In combination, the effect of phased autologous skin grafting in patients with severe second‑degree burns on the dorsum of the hand was ideal, as it significantly reduced inflammatory response and was beneficial to the functional recovery of the hand. Therefore, phased autologous skin grafting is worthy of wider application.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Guchlerner M, Brockmann MA and Pitz S: Periocular necrobiotic xanthogranuloma with mono- and biclonal gammopathy. Klin Monbl Augenheilkd. 237:41–45. 2020.PubMed/NCBI View Article : Google Scholar : (In German).

2 

Wang KA, Wu GS, Sun Y and Xia ZF: Advances in the research of prevention and treatment of postburn contractures of hand. Zhonghua Shao Shang Za Zhi. 33:58–61. 2017.PubMed/NCBI View Article : Google Scholar : (In Chinese).

3 

Li G, Li YY and Sun JE: Comparison of the efficacy of allogeneic (porcine) skin covering followed by second-stage implantation method and normal one-stage implantation method in the treatment of refractory wounds. Modern Diagnosis Ther. 30:2790–2792. 2019.

4 

Argirova M and Hadzhiyski O: Acute dorsal hand burns in children. Ann Burns Fire Disasters. 19:22–25. 2006.PubMed/NCBI

5 

Ciudad P, Date S, Orfaniotis G, Dower R, Nicoli F, Maruccia M, Lin SP, Chuang CY, Chuang TY, Wang GJ and Chen HC: Delayed grafting for banked skin graft in lymph node flap transfer. Int Wound J. 14:125–129. 2017.PubMed/NCBI View Article : Google Scholar

6 

Snelling CF: Delayed skin graft application following burn scar release of the face and hand. Ann Plast Surg. 10:349–358. 1983.PubMed/NCBI View Article : Google Scholar

7 

Sun L and Patel AJ: Outcomes of split vs. full-thickness skin grafts in scalp reconstruction in outpatient local anaesthetic theatre. Scars Burn Heal. 7(20595131211056542)2021.PubMed/NCBI View Article : Google Scholar

8 

Kanapathy M and Mosahebi A: Comparative study on the donor site aesthetic outcome between epidermal graft and split-thickness skin graft. Int Wound J. 16:354–359. 2019.PubMed/NCBI View Article : Google Scholar

9 

Chan QE, Barzi F, Harvey JG and Holland AJ: Functional and cosmetic outcome of full-versus split-thickness skin grafts in pediatric palmar surface burns: A prospective, independent evaluation. J Burn Care Res. 34:232–236. 2013.PubMed/NCBI View Article : Google Scholar

10 

Baryza MJ and Baryza GA: The vancouver scar Scale: An administration tool and its interrater reliability. J Burn Care Rehabil. 16:535–538. 1995.PubMed/NCBI View Article : Google Scholar

11 

Alsaif A, Karam M, Hayre A, Abul A, Aldubaikhi A and Kahlar N: Full thickness skin graft versus split thickness skin graft in paediatric patients with hand burns: Systematic review and meta-analysis:. Burns. 49:1017–1027. 2022.PubMed/NCBI View Article : Google Scholar

12 

Xu Z, Zhang Z, Wang B, Sun Y, Guo Y, Gao W and Qin G: The application of delayed skin grafting combined traction in severe joint cicatricial contracture. Zhonghua Zheng Xing Wai Ke Za Zhi. 30:424–427. 2014.PubMed/NCBI(In Chinese).

13 

Hong YK, Chang YH, Lin YC, Chen B, Guevara BEK and Hsu CK: Inflammation in wound healing and pathological scarring. Adv Wound Care (New Rochelle). 12:288–300. 2023.PubMed/NCBI View Article : Google Scholar

14 

Zhang D, Li B and Zhao M: Therapeutic strategies by regulating interleukin family to suppress inflammation in hypertrophic scar and keloid. Front Pharmacol. 12(667763)2021.PubMed/NCBI View Article : Google Scholar

15 

Enomoto A, Shimoide T, Kinoshita Y, Sukedai M and Hamada S: Application of an oral appliance for endotracheal tube fixation in facial burn patients. Br J Oral Maxillofac Surg. 59:127–128. 2021.PubMed/NCBI View Article : Google Scholar

16 

Flores O, Tyack Z, Stockton K and Paratz JD: The use of exercise in burns rehabilitation: A worldwide survey of practice. Burns. 46:322–332. 2019.PubMed/NCBI View Article : Google Scholar

17 

Peng H, Liang PF and Wang  : Influences of different rehabilitative methods on function of hands and psychological anxiety of patients with deeply burned hands retaining denatured dermis and grafting large autologous skin. Zhonghua Shao Shang Za Zhi. 33:272–276. 2017.PubMed/NCBI View Article : Google Scholar : (In Chinese).

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Sun J, Su S, Jiao S, Li G, Zhang Z, Lin W and Zhang S: A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand. Exp Ther Med 27: 238, 2024.
APA
Sun, J., Su, S., Jiao, S., Li, G., Zhang, Z., Lin, W., & Zhang, S. (2024). A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand. Experimental and Therapeutic Medicine, 27, 238. https://doi.org/10.3892/etm.2024.12526
MLA
Sun, J., Su, S., Jiao, S., Li, G., Zhang, Z., Lin, W., Zhang, S."A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand". Experimental and Therapeutic Medicine 27.5 (2024): 238.
Chicago
Sun, J., Su, S., Jiao, S., Li, G., Zhang, Z., Lin, W., Zhang, S."A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand". Experimental and Therapeutic Medicine 27, no. 5 (2024): 238. https://doi.org/10.3892/etm.2024.12526
Copy and paste a formatted citation
x
Spandidos Publications style
Sun J, Su S, Jiao S, Li G, Zhang Z, Lin W and Zhang S: A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand. Exp Ther Med 27: 238, 2024.
APA
Sun, J., Su, S., Jiao, S., Li, G., Zhang, Z., Lin, W., & Zhang, S. (2024). A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand. Experimental and Therapeutic Medicine, 27, 238. https://doi.org/10.3892/etm.2024.12526
MLA
Sun, J., Su, S., Jiao, S., Li, G., Zhang, Z., Lin, W., Zhang, S."A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand". Experimental and Therapeutic Medicine 27.5 (2024): 238.
Chicago
Sun, J., Su, S., Jiao, S., Li, G., Zhang, Z., Lin, W., Zhang, S."A prospective analysis of the efficacy of phase II autologous skin grafting on deep second‑degree burns on the dorsum of the hand". Experimental and Therapeutic Medicine 27, no. 5 (2024): 238. https://doi.org/10.3892/etm.2024.12526
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team