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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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February-2026 Volume 31 Issue 2

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report Open Access

Calcifying fibrous tumours of the diaphragm: A case report and literature review

  • Authors:
    • Sijia Guo
    • Wenya Han
    • Lingling Yuan
    • Hansheng Wang
    • Ge Cheng
    • Yaxin Tuo
    • Chuanyong Xiao
    • Jialong Guo
    • Meifang Wang
  • View Affiliations / Copyright

    Affiliations: Department of Pulmonary and Critical Care Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China, Department of Pathology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China, Medical Imaging Centre, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China, Department of Cardiothoracic surgery, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China
    Copyright: © Guo et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 47
    |
    Published online on: December 5, 2025
       https://doi.org/10.3892/etm.2025.13042
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Abstract

Calcifying fibrous tumour (CFT), also known as calcifying fibrous pseudotumor, is a rare benign tumour that accounts for ~0.5% of all diaphragmatic tumours. It affects predominantly children and young adults, with a slight female predilection. Owing to its non‑specific clinical presentations and imaging features along with its indolent growth pattern, CFT is frequently misdiagnosed. Histopathological examination remains the diagnostic gold standard, while complete surgical excision constitutes the mainstay of treatment. The present study reported a rare case of diaphragmatic CFT. Furthermore, all the case reports of CFT published in English in the PubMed database from 1946 to 2024 and detailed its diagnostic workup and therapeutic management were reviewed to enhance the recognition of CFT. The present study aims to reduce the number of missed diagnoses and misdiagnoses of CFT and the number of unnecessary high‑risk surgeries, thereby improving the quality of life of patients with CFT.

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Copy and paste a formatted citation
Spandidos Publications style
Guo S, Han W, Yuan L, Wang H, Cheng G, Tuo Y, Xiao C, Guo J and Wang M: Calcifying fibrous tumours of the diaphragm: A case report and literature review. Exp Ther Med 31: 47, 2026.
APA
Guo, S., Han, W., Yuan, L., Wang, H., Cheng, G., Tuo, Y. ... Wang, M. (2026). Calcifying fibrous tumours of the diaphragm: A case report and literature review. Experimental and Therapeutic Medicine, 31, 47. https://doi.org/10.3892/etm.2025.13042
MLA
Guo, S., Han, W., Yuan, L., Wang, H., Cheng, G., Tuo, Y., Xiao, C., Guo, J., Wang, M."Calcifying fibrous tumours of the diaphragm: A case report and literature review". Experimental and Therapeutic Medicine 31.2 (2026): 47.
Chicago
Guo, S., Han, W., Yuan, L., Wang, H., Cheng, G., Tuo, Y., Xiao, C., Guo, J., Wang, M."Calcifying fibrous tumours of the diaphragm: A case report and literature review". Experimental and Therapeutic Medicine 31, no. 2 (2026): 47. https://doi.org/10.3892/etm.2025.13042
Copy and paste a formatted citation
x
Spandidos Publications style
Guo S, Han W, Yuan L, Wang H, Cheng G, Tuo Y, Xiao C, Guo J and Wang M: Calcifying fibrous tumours of the diaphragm: A case report and literature review. Exp Ther Med 31: 47, 2026.
APA
Guo, S., Han, W., Yuan, L., Wang, H., Cheng, G., Tuo, Y. ... Wang, M. (2026). Calcifying fibrous tumours of the diaphragm: A case report and literature review. Experimental and Therapeutic Medicine, 31, 47. https://doi.org/10.3892/etm.2025.13042
MLA
Guo, S., Han, W., Yuan, L., Wang, H., Cheng, G., Tuo, Y., Xiao, C., Guo, J., Wang, M."Calcifying fibrous tumours of the diaphragm: A case report and literature review". Experimental and Therapeutic Medicine 31.2 (2026): 47.
Chicago
Guo, S., Han, W., Yuan, L., Wang, H., Cheng, G., Tuo, Y., Xiao, C., Guo, J., Wang, M."Calcifying fibrous tumours of the diaphragm: A case report and literature review". Experimental and Therapeutic Medicine 31, no. 2 (2026): 47. https://doi.org/10.3892/etm.2025.13042
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