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Experimental and Therapeutic Medicine
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

Case Report Open Access

Bilateral presacral tumors in an adult female patient: A case report and literature review

Yongping Hong, Guofeng Li, Liyu Zhou
Article Number: 61
Published online on: 29 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑34a suppresses breast cancer cell proliferation and invasion by targeting Notch1

Xiaoping Rui, Haibin Zhao, Xianqiu Xiao, Li Wang, Lin Mo, Yao Yao
Article Number: 60
Published online on: 22 December 2025

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Article Open Access

Therapeutic efficacy of quercetin in experimental pulmonary fibrosis: A meta‑analysis

Lanhua Cai, Long Chen, Chunmei Lin
Article Number: 59
Published online on: 22 December 2025

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Article Open Access

N‑(p‑Coumaroyl) serotonin mitigates inflammatory responses in lipopolysaccharide‑stimulated RAW264.7 cells and phorbol 12‑myristate 13‑acetate‑stimulated A549 cells through NF‑κB and MAPK inactivation

Seok Han Yun, Chang Hyeon Jeon, Soo-Jin Park, Hee Jae Lee, Ok-Kyoung Kwon, Jae-Won Lee
Article Number: 58
Published online on: 22 December 2025

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Article

Association of thrombocytopenia with deep vein thrombosis in patients with acute exacerbations of chronic obstructive pulmonary disease: A retrospective study

Yufang Guo, Li Wang, Zexu Wang, Yongjun Wang, Qiuqi Lin, Xiuwei Zhang, Liangquan Wu, Bing Wan
Article Number: 57
Published online on: 22 December 2025

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Article Open Access

Analysis of PANoptosis‑related genes in septic cardiomyopathy by bioinformatics, machine learning and experimental validation

Yiheng Yang, Jiahao Zou, Peng Yang, Zhenzhong Zheng, Qingshan Tian
Article Number: 56
Published online on: 16 December 2025

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Article Open Access

Long‑term effects of orthokeratology on moderate myopia progression in children: A 3‑year prospective study

Yibao Li, Rui Zhang, Yu Su, Rongfeng Liao
Article Number: 55
Published online on: 16 December 2025

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Article Open Access

Metabolic gene polymorphisms and type 2 diabetes mellitus risk: A systematic review and meta‑analyses

Dono Indarto, Tri N. Susilawati, Yuliana H. Suselo, Purwo S. Rejeki, Yuxi Feng, Yohanes C. Wibowo, Melani R. Mahanani
Article Number: 54
Published online on: 16 December 2025

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Article Open Access

Impact of MGMT methylation on overall survival in solid tumors: A systematic review and meta‑analysis

Abdulla Alzibdeh, Ala'a Khanfar, Maysa Al-Hussaini, Ramiz Abuhijlih, Issa Mohamad, Hikmat Abdel-razeq, Fawzi Abuhijla
Article Number: 53
Published online on: 15 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑216b‑3p inhibits lung adenocarcinoma cell growth via regulating PDZ binding kinase/T‑LAK‑cell‑originated protein kinase

Yaqin Chai, Huijun Xue, Yanmei Wu, Xiaomei Du, Zhuohong Zhang, Yinliang Zhang, Lili Zhang, Shuanbao Zhang, Zhiguo Zhang, Zhiwen Xue
Article Number: 52
Published online on: 15 December 2025

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Case Report Open Access

Cardiac mass in a patient with HIV infection: A case report and literature review

Adrian Gradinaru, Andrei Colita, Ionela Muraretu, Mircea Bajdechi, Anca Mihailescu, Carmen Saguna, Radoi Roxana, Adriana-Luminita Gurghean
Article Number: 51
Published online on: 15 December 2025

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Article Open Access

Development and internal validation of a clinical nomogram for predicting bronchopulmonary dysplasia in preterm infants

Yan-Sha Pan, Lan Xiao, Wen-Bin Dong, Jia-Wen Dang
Article Number: 50
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑519a inhibits the proliferation and promotes the apoptosis of ovarian cancer cells through targeting signal transducer and activator of transcription 3

Fei Tian, Ligang Jia, Zhaoping Chu, Hua Han, Yuan Zhang, Jianhui Cai
Article Number: 49
Published online on: 09 December 2025

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Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Case Report Open Access

Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Case Report

Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Article Open Access

Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Article Open Access

Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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Article Open Access

The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Article Open Access

Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Article Open Access

Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Article Open Access

Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Article Open Access

Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Article Open Access

Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Article Open Access

Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Article Open Access

Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Article Open Access

Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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Journal Cover
September-2026 Volume 32 Issue 3

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Impact Factor: 2.2

Article Open Access

A prospective study of non‑invasive preimplantation genetic testing for Rh status, sex prediction and mtDNA copy number analysis using ddPCR on spent culture media

Ece Gumusoglu-Acar, Sude Subasi, Merve Cebeci, Zehranur Sisman, Ecenur Karadisogullari, Burcin Karamustafaoglu-Balci, Hale Goksever-Celik, Ercan Bastu, Faruk Buyru, Tuba Gunel
Article Number: 251
Published online on: 20 July 2026

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Review Open Access

m6A methylation regulatory network in pulmonary fibrosis: Molecular mechanisms from RNA stability to cellular phenotype transition (Review)

Lielong Mao, Dekun Zhou, Guoqi Zhou, Xiaofeng Lu
Article Number: 250
Published online on: 20 July 2026

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Retraction Open Access

[Retracted] Dapagliflozin can alleviate renal fibrosis in rats with streptozotocin‑induced type 2 diabetes mellitus

Song Xue, Ying-Xuan Li, Xiao-Xiao Lu, Wei Tang
Article Number: 249
Published online on: 20 July 2026

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Review Open Access

Ubiquitin‑driven regulation of immune checkpoints in lung cancer: Mechanisms and therapeutic implications (Review)

Lin Chai, Lin-Rong Pang, Yi-Ting Li, Jia-Hui Wang, Jun Chen, Zu-Guo Yuan, Xiao-Feng Jin
Article Number: 248
Published online on: 15 July 2026

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Case Report

Severe delayed diaphragmatic hernia with total gastric migration after cytoreductive surgery, a rare complication: A case report

Marine Stouvenel, Houssein El Hajj, Patricia Pautier, Philippe Morice, Sébastien Gouy
Article Number: 247
Published online on: 15 July 2026

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Retraction Open Access

[Retracted] An altered expression of genes involved in the regulation of ion channels in atrial myocytes is correlated with the risk of atrial fibrillation in patients with heart failure  

Mei Gao, Jiangrong Wang, Zhongsu Wang, Yong Zhang, Hui Sun, Xinxing Xie, Yinglong Hou
Article Number: 246
Published online on: 13 July 2026

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Case Report Open Access

Angiomatous meningioma with cystic degeneration: A case report

Zetong Bai, Yaojun Song, Haiguang Liu, Yan Wang, Shian Yin, Xichao Wen, Haipeng Liu, Jiayu Chen, Haipeng Xie, Zhaomu Zeng
Article Number: 245
Published online on: 10 July 2026

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Article Open Access

Mitochondrial autophagy promotion contributes to the protective effects of BYHWD glycoside‑enriched fraction against OGD/R‑induced injury in H9C2 cells

Xujiao Hu, Jingjing Fang, Tong Sun, Jiheng Feng, Fangmei Zhou, Mingyuan Zhou, Zhishan Ding
Article Number: 244
Published online on: 09 July 2026

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Correction Open Access

[Corrigendum] Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatory‑fibrosis through the NF‑κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory‑fibrosis by inhibiting endogenous Nampt

Ye Chen, Yuzhen Liang, Tingting Hu, Riming Wei, Congjie Cai, Ping Wang, Lingyu Wang, Wei Qiao, Leping Feng
Article Number: 243
Published online on: 08 July 2026

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Case Report Open Access

A rare spinal cord infarction caused by aortic mural thrombosis in a patient with cancer and the associated diagnostic challenges due to it mimicking spinal cord compression: A case report

Nobuhito Hara, Shunsuke Okazaki, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Masaki Kobayashi, Hitoshi Nakagawa, Mako Iwata, Toshiteru Miyasaka, Yuji Nitta, Maiko Takeda, Masayuki Takeda
Article Number: 242
Published online on: 07 July 2026

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Case Report Open Access

Occupational exposure to freshwater crustaceans as a route of paragonimiasis presenting with eosinophilic pleural effusion misdiagnosed as tuberculous pleurisy: A case report and literature review

Xin Li, Peng Wang, Dan Cheng, Xiaoqin Peng, Lu Xue, Jiankun Wang, Jun Li
Article Number: 241
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Downregulation of miR‑183 inhibits the growth of PANC‑1 pancreatic cancer cells in vitro and in vivo, and increases chemosensitivity to 5‑fluorouracil and gemcitabine  

Xiaoping Yang, Wei Wang, Xiong Zhang, Qi Zou, Lei Cai, Bo Yu
Article Number: 240
Published online on: 07 July 2026

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Case Report

Stepwise endoscopic and surgical management of spontaneous esophageal rupture with severe mediastinal contamination: A case report

Yan Zhang, Yuan Yao, Jing Cao, Ning Zhong
Article Number: 239
Published online on: 06 July 2026

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Review Open Access

Kidney organoids as models for hereditary kidney diseases: Toward precision medicine (Review)

Sheng Cui, Tianlei Chen, Yun Zou, Min Li, Hua Zhou, Jingting Jiang, Min Yang
Article Number: 238
Published online on: 06 July 2026

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Article Open Access

Role of fine‑needle aspiration cytology and cell morphology in determining the histogenesis of salivary gland lesions

Bisharah Soudah, Mahmoud Abbas
Article Number: 237
Published online on: 06 July 2026

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Article Open Access

Risk factors associated with treatment failure in peritoneal dialysis‑associated peritonitis

Yao Jiang, Xiaoyan Luo, Tao Peng, Yang Li
Article Number: 236
Published online on: 06 July 2026

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Article Open Access

Role and insights of human papillomavirus E5 oncoprotein in cervical carcinogenesis

Jyoti Rani, Sandeep Sisodiya, Kapil Kumar, Sandeep Kumar, Asiya Khan, Ekta Gupta, Showket Hussain
Article Number: 235
Published online on: 06 July 2026

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Case Report Open Access

Total knee arthroplasty for the treatment of osteoarthritis secondary to bilateral congenital patellar dislocation: A case report and review of the literature

Haishan Lin, Ding Yang, Xuming Ding, Xingjia Yang, Yaohua Wang
Article Number: 234
Published online on: 06 July 2026

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Review Open Access

Research progress of lactylation modification in tumors (Review)

Shi-Chao Fang, Zhi-Zhou Shi
Article Number: 233
Published online on: 06 July 2026

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Retraction Open Access

[Retracted] Resveratrol attenuates type 2 diabetes mellitus by mediating mitochondrial biogenesis and lipid metabolism via Sirtuin type 1

Ming-Ming Cao, Xi Lu, Guo-Dong Liu, Ying Su, Yan-Bo Li, Jin Zhou
Article Number: 232
Published online on: 01 July 2026

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Review Open Access

Clinical differentiation between pediatric pulmonary tuberculosis and Mycoplasma pneumoniae pneumonia (Review)

Zong Wan, Renjie Qi, Qiushi Yang, Huan Li, Shusong Ruan
Article Number: 231
Published online on: 30 June 2026

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Journal Cover
October-2026 Volume 32 Issue 4

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Impact Factor: 2.2

Case Report Open Access

Clinicopathological analysis of neuroendocrine carcinoma discovered incidentally in hemorrhoids: A case report and literature review

Bin Huang, Haiyan Zhou, Jianping Shi, Hongsheng Liu
Article Number: 276
Published online on: 12 August 2026

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Article Open Access

Mechanism of microRNA‑30b‑5p enhancing the response of MDA‑MB‑231 cells to cisplatin by regulating RAP1B expression

Kewei Tang, Site Bai, Yajun Tong, Songjiang Liu, Leilan Yin, Ludi Ou, Qinghua Yin, Qiang Zhou
Article Number: 275
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Platelet‑rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors

Guilin Huang, Sha Hua, Tuanmin Yang, Jianbing Ma, Wenxing Yu, Xiujin Chen
Article Number: 274
Published online on: 12 August 2026

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Article Open Access

Establishment of a novel asymmetric force degenerative lumbar scoliosis aging bipedal rat model

Jing Peng, Daigui Cao, Xu Zhou, Zhiwei Liu, Xinxing Wang, Anwei Zhang, Kai Shen
Article Number: 273
Published online on: 11 August 2026

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Case Report Open Access

Rapid diagnosis of Chlamydia psittaci pneumonia with pleural effusion using multiplex PCR‑based targeted next‑generation sequencing: A case report

Yang Jin, Liqun He, Jiankun Wang, Tao Ren, Hansheng Wang, Yue Wang
Article Number: 272
Published online on: 11 August 2026

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Article Open Access

Sanguinarine chloride inducing ferroptosis and downregulating GPX4 expression in liver cancer: An integrated in silico, in vitro and in vivo study

Wen Ouyang, Jianxin Gao, Jing Liu, Lulu Qin, Bang Liu, Ying He, Dai Zhou
Article Number: 271
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Activated protein C overexpression suppresses the pyroptosis of subarachnoid hemorrhage model cells by regulating the NLRP3 inflammasome pathway

Ai Yan, Xuyan Pan, Xianqiang Wen, Xiaohu Nie, Yuntao Li
Article Number: 270
Published online on: 10 August 2026

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Case Report Open Access

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Case Report

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Experimental evaluation of Curcuma Longa in docetaxel‑induced systemic toxicity: Functional hepatorenal and target organ analysis

Isabella Morais Tavares Huber, Leonardo Garcia Velasquez, Emerson Luiz Botelho Lourenço, Salviano Tramontin Bellettini, Guilherme Donadel, João Francisco Velasquez Matumoto, Sandra Marisa Pelloso, Maria Dalva De Barros Carvalho, Stéfane Lele Rossoni, Mariana Morais Tavares Colferai, Diego Ricardo Colferai, Roberto Kenji Nakamura Cuman
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Case Report Open Access

Nasopharyngeal carcinoma with inguinal lymph node metastasis: A case report

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Mesut Pekmez, Ümit Özçelik, Kemal Yandakçi, Alper Bilal Özkardeş
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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTEN

Lingyan Zhang, Zibin Bu, Juan Shen, Liping Shang, Yuanyuan Chen, Ping Zhang, Yan Wang
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Qian Song, Ping'an Shi, Peng Tian, Aijun Chao, Yinguang Zhang, Qiang Dong
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Spatial specificity of Epstein‑Barr virus infection in gastric cancer: A 44‑case clinicopathological analysis

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Crocin I delays cellular senescence potentially via modulating SIRT1/PKM2 expression to improve lactate homeostasis in vitro

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Case Report

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Retraction Open Access

[Retracted] Reduced expression levels of the death‑associated protein kinase and E‑cadherin are correlated with the development of esophageal squamous cell carcinoma

Jianwen Zhai, Xiaogang Yang, Yanli Zhang, Qingbin Qi, Jigang Hu, Qiaomei Wang
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Hematopoietic cell‑specific knockout Hspa9 impairs natural killer cell function and alters the Akt/mTOR axis in mice

Xiaokang Zeng, Jieyu Zhang, Caiying Liang, Jie Yao, Zuqiang Wu
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Published online on: 24 July 2026

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Comparative study on mouse models of acute exacerbation of pulmonary fibrosis

Xu Ye, Mingrui Zhang, Mengying Liu, Huihui Zhu, Xiaoling Ye, Cheng Jiang, Qi Li, Xinmei Huang, Mengshu Cao
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Correction Open Access

[Corrigendum] TBL1XR1 as a potential therapeutic target that promotes epithelial‑mesenchymal transition in lung squamous cell carcinoma

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