Extra-nodal natural killer/T cell lymphoma, nasal-type, treated by concurrent chemoradiotherapy

Yoshikawa,Nobuhiko; Inomata,Taisuke; Shinbo,Taiju; Takahashi,Masatsugu; Uesugi,Yasuo; Narumi,Yoshihumi

doi:10.3892/etm_00000070

May-June 2010 Volume 1 Issue 3

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May-June 2010 Volume 1 Issue 3

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Article

Extra-nodal natural killer/T cell lymphoma, nasal-type, treated by concurrent chemoradiotherapy

Authors:
- Nobuhiko Yoshikawa
- Taisuke Inomata
- Taiju Shinbo
- Masatsugu Takahashi
- Yasuo Uesugi
- Yoshihumi Narumi
View Affiliations / Copyright

Affiliations: Department of Radiology, Osaka Medical College, Osaka 569-8686, Japan. rad101@poh.osaka-med.ac.jp
Pages: 453-455
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Published online on: May 1, 2010

https://doi.org/10.3892/etm_00000070
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Abstract

The present study reports on a case of extra-nodal natural killer/T cell lymphoma, nasal-type (ENKL), stage IIEA, in a 50-year-old woman who presented with a white tumor on a refractory ulcer on the gum. Concurrent chemoradiotherapy was administered, and effected a partial response. However, tumor recurrence was observed 5 months after the final diagnosis, and the patient succumbed 1 month after recurrence. Although a definitive treatment for ENKL has yet to be established due to its rarity, radiation therapy (RT) is crucial to therapy, as ENKL is very sensitive to RT. However, treatment with radiation levels above 50 Gy with an extended RT field are required for a favorable outcome. The development of novel chemotherapy regimens may therefore be useful. Additionally, autologous or allogenic hematopoietic stem-cell transplantation may prove to be a promising approach.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Extra-nodal natural killer/T cell lymphoma, nasal-type, treated by concurrent chemoradiotherapy

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