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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2010 Volume 1 Issue 3

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Impact Factor: 2.3

Article Open Access

Medicinal mushroom Phellinus linteus as an alternative cancer therapy (Review)

Daniel Sliva
Pages: 407-411
Published online on: 01 May 2010

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Article

Involvement of calpain in colorectal adenocarcinomas (Review)

Ponniah Selvakumar, Rajendra K. Sharma
Pages: 413-417
Published online on: 01 May 2010

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Article Open Access

Tubulin α-6 chain is a stably expressed reference gene in archival samples of normal oral tissue and oral squamous cell carcinoma

Matilda Rentoft, Sara Hultin, Philip J. Coates, Göran Laurell, Karin Nylander
Pages: 419-423
Published online on: 01 May 2010

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Article Open Access

Clinical and immunological assessment in breast cancer patients receiving anticancer therapy and bovine dialyzable leukocyte extract as an adjuvant

Humberto H. Lara, Liliana Ixtepan-Turrent, Elsa N. Garza-Treviño, Reyes Tamez-Guerra, Cristina Rodriguez-Padilla
Pages: 425-431
Published online on: 01 May 2010

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Article

Infective endocarditis associated with acute renal failure: Repeat renal biopsy and successful recovery

Aifeng Wang, Yongping Wang, Guobao Wang, Zhanmei Zhou, Xiaobing Yang
Pages: 433-436
Published online on: 01 May 2010

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Article

Expression of β-catenin and REG Iα in relation to cell proliferative ability in salivary gland tumors

Yuko Hakata, Hirokazu Fukui, Akira Sekikawa, Hidetsugu Yamagishi, Kazuhito Ichikawa, Shigeki Tomita, Johji Imura, Hitoshi Kawamata, Yutaka Imai, Takahiro Fujimori
Pages: 437-443
Published online on: 01 May 2010

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Article

Expression of ERCC1 and class III β-tubulin is associated with the survival of resected stage III non-small cell lung cancer patients treated with induction chemoradiotherapy using carboplatin-taxane

Cheng-Long Huang, Kyuichi Kadota, Dage Liu, Masaki Ueno, Nariyasu Nakasima, Shinya Ishikawa, Masashi Gotoh, Noriyuki Misaki, Sung-Soo Chang, Hiroyasu Yokomise
Pages: 445-451
Published online on: 01 May 2010

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Article

Extra-nodal natural killer/T cell lymphoma, nasal-type, treated by concurrent chemoradiotherapy

Nobuhiko Yoshikawa, Taisuke Inomata, Taiju Shinbo, Masatsugu Takahashi, Yasuo Uesugi, Yoshihumi Narumi
Pages: 453-455
Published online on: 01 May 2010

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Article

Dynamic changes in E-cadherin gene promoter methylation during metastatic progression in papillary thyroid cancer

Kirk Jensen, Aneeta Patel, Victoria Hoperia, Alexander Larin, Andrew Bauer, Vasyl Vasko
Pages: 457-462
Published online on: 01 May 2010

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Article

Soluble VCAM-1 and its relation to disease progression in colorectal carcinoma

Yoshinaga Okugawa, Chikao Miki, Yuji Toiyama, Yuki Koike, Takeshi Yokoe, Susumu Saigusa, Kouji Tanaka, Yasuhiro Inoue, Masato Kusunoki
Pages: 463-469
Published online on: 01 May 2010

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Article

Proliferation of human lung cancer in an orthotopic transplantation mouse model

Yun Kang, Motoko Omura, Akiko Suzuki, Chumpol Theeraladanon, Takashi Oka, Yoshihiro Nakagami, Atsushi Suzuki, Yoji Nagashima, Tomio Inoue
Pages: 471-475
Published online on: 01 May 2010

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Article

Effect of fibroblast growth factor-2 on dental pulp cells derived from human deciduous teeth in vitro

Tomokazu Hasegawa, Naoyuki Chosa, Takeyoshi Asakawa, Yoshitaka Yoshimura, Asami Asakawa, Akira Ishisaki, Mitsuro Tanaka
Pages: 477-480
Published online on: 01 May 2010

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Article

Consultation clinics for complementary and alternative medicine at Japanese university hospitals: An analysis at Tokushima University Hospital

Hiroaki Yanagawa, Junji Terao, Eiji Takeda, Yoshihisa Takaishi, Yoshiki Kashiwada, Kazuyoshi Kawazoe, Shuji Fushitani, Koichiro Tsuchiya, Aiko Yamauchi, Chiho Sato, Minoru Irahara
Pages: 481-483
Published online on: 01 May 2010

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Article

Effects of pre-operative transcatheter arterial chemoembolization for resectable hepatocellular carcinoma: Implication of circulating cancer cells by detection of α-fetoprotein mRNA

Masahiro Murakami, Hiroaki Nagano, Shogo Kobayashi, Hiroshi Wada, Masato Nakamura, Shigeru Marubashi, Hidetoshi Eguchi, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki, Masaki Mori
Pages: 485-491
Published online on: 01 May 2010

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Article

Correlation of granulin expression in intracranial meningiomas to clinical parameters

Choong H. Kim, Jin H. Cheong, Jae M. Kim
Pages: 493-496
Published online on: 01 May 2010

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Article

CD318/CUB-domain-containing protein 1 expression on cord blood hematopoietic progenitors

Hiromi Takeda, Yoshihiro Fujimori, Shunro Kai, Hiroyasu Ogawa, Takashi Nakano
Pages: 497-501
Published online on: 01 May 2010

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Article

Post mortem contrast-enhanced computed tomography in a case of sudden death from acute pulmonary thromboembolism

Kiyoshi Kikuchi, Ko-ichi Kawahara, Chiyoko Tsuji, Yutaka Tajima, Terukazu Kuramoto, Miwako Shihara, Yukari Koga, Naoto Shiomi, Hisaaki Uchikado, Yoko Morimoto, Naoki Miura, Kentaro Mera, Yoshiko Ohno, Naohisa Miyagi, Teruto Hashiguchi, Ikuro Maruyama, Naohumi Hayabuchi, Kenji Nakayama, Minoru Shigemori
Pages: 503-505
Published online on: 01 May 2010

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Article

Evaluation of serum iron levels during FOLFOX4 and FOLFIRI therapies

Satomi Mashiko, Isao Nagaoka, Masayuki Kitajima, Tomoo Watanabe, Kazuhiko Nishimura, Shunji Futagawa, Takumi Ochiai
Pages: 507-511
Published online on: 01 May 2010

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Article

Potentiation of the growth inhibition activity of 2-({4-[4-(acridin-9-ylamino)phenylthio]phenyl}(2-hydroxyethyl)amino)ethan-1-ol (CK0402) by Herceptin in SKBR-3 human breast cancer cells

Yuan-Wan Sun, Ting-Kuang Niu, Jin-Ming Yang, Chul-Hoon Kwon, Kuen-Yuan Chen, Kun-Ming Chen
Pages: 513-518
Published online on: 01 May 2010

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Article

Epigenetic activation of E-cadherin is a candidate therapeutic target in human hepatocellular carcinoma

Xuemei Qiu, Fengchang Qiao, Xianwei Su, Zhujiang Zhao, Hong Fan
Pages: 519-523
Published online on: 01 May 2010

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Article

Impact of human papillomavirus genotype on response to treatment and survival in patients receiving radiotherapy for squamous cell carcinoma of the cervix

Jannatul Ferdousi, Yutaka Nagai, Tsuyoshi Asato, Makoto Hirakawa, Morihiko Inamine, Wataru Kudaka, Ken-ichi Kariya, Yoichi Aoki
Pages: 525-530
Published online on: 01 May 2010

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Article

Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol

Pamela Cruz, Cristian Torres, María E. Ramírez, María J. Epuñán, Luis E. Valladares, Walter D. Sierralta
Pages: 531-536
Published online on: 01 May 2010

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Article

Improving gene transfer in human renal carcinoma cells: Utilization of adenovirus vectors containing chimeric type 5 and type 35 fiber proteins

Bishnu Acharya, Shuji Terao, Toru Suzuki, Michio Naoe, Katsuyuki Hamada, Hiroyuki Mizuguchi, Akinobu Gotoh
Pages: 537-540
Published online on: 01 May 2010

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Journal Cover
January-2026 Volume 31 Issue 1

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Journal Metrics

Impact Factor: 2.3

Article Open Access

Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Article Open Access

Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Article Open Access

Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Article Open Access

Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Review Open Access

Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Article Open Access

Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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Retraction Open Access

[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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Article Open Access

A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Case Report Open Access

Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Article Open Access

Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Article Open Access

Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Article Open Access

Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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Correction Open Access

[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Impact Factor: 2.3

Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Case Report Open Access

Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Case Report

Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Article Open Access

Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Article Open Access

Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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Article Open Access

The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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