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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2010 Volume 1 Issue 3

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Impact Factor: 2.3

Article Open Access

Medicinal mushroom Phellinus linteus as an alternative cancer therapy (Review)

Daniel Sliva
Pages: 407-411
Published online on: 01 May 2010

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Article

Involvement of calpain in colorectal adenocarcinomas (Review)

Ponniah Selvakumar, Rajendra K. Sharma
Pages: 413-417
Published online on: 01 May 2010

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Article Open Access

Tubulin α-6 chain is a stably expressed reference gene in archival samples of normal oral tissue and oral squamous cell carcinoma

Matilda Rentoft, Sara Hultin, Philip J. Coates, Göran Laurell, Karin Nylander
Pages: 419-423
Published online on: 01 May 2010

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Article Open Access

Clinical and immunological assessment in breast cancer patients receiving anticancer therapy and bovine dialyzable leukocyte extract as an adjuvant

Humberto H. Lara, Liliana Ixtepan-Turrent, Elsa N. Garza-Treviño, Reyes Tamez-Guerra, Cristina Rodriguez-Padilla
Pages: 425-431
Published online on: 01 May 2010

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Article

Infective endocarditis associated with acute renal failure: Repeat renal biopsy and successful recovery

Aifeng Wang, Yongping Wang, Guobao Wang, Zhanmei Zhou, Xiaobing Yang
Pages: 433-436
Published online on: 01 May 2010

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Article

Expression of β-catenin and REG Iα in relation to cell proliferative ability in salivary gland tumors

Yuko Hakata, Hirokazu Fukui, Akira Sekikawa, Hidetsugu Yamagishi, Kazuhito Ichikawa, Shigeki Tomita, Johji Imura, Hitoshi Kawamata, Yutaka Imai, Takahiro Fujimori
Pages: 437-443
Published online on: 01 May 2010

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Article

Expression of ERCC1 and class III β-tubulin is associated with the survival of resected stage III non-small cell lung cancer patients treated with induction chemoradiotherapy using carboplatin-taxane

Cheng-Long Huang, Kyuichi Kadota, Dage Liu, Masaki Ueno, Nariyasu Nakasima, Shinya Ishikawa, Masashi Gotoh, Noriyuki Misaki, Sung-Soo Chang, Hiroyasu Yokomise
Pages: 445-451
Published online on: 01 May 2010

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Article

Extra-nodal natural killer/T cell lymphoma, nasal-type, treated by concurrent chemoradiotherapy

Nobuhiko Yoshikawa, Taisuke Inomata, Taiju Shinbo, Masatsugu Takahashi, Yasuo Uesugi, Yoshihumi Narumi
Pages: 453-455
Published online on: 01 May 2010

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Article

Dynamic changes in E-cadherin gene promoter methylation during metastatic progression in papillary thyroid cancer

Kirk Jensen, Aneeta Patel, Victoria Hoperia, Alexander Larin, Andrew Bauer, Vasyl Vasko
Pages: 457-462
Published online on: 01 May 2010

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Article

Soluble VCAM-1 and its relation to disease progression in colorectal carcinoma

Yoshinaga Okugawa, Chikao Miki, Yuji Toiyama, Yuki Koike, Takeshi Yokoe, Susumu Saigusa, Kouji Tanaka, Yasuhiro Inoue, Masato Kusunoki
Pages: 463-469
Published online on: 01 May 2010

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Article

Proliferation of human lung cancer in an orthotopic transplantation mouse model

Yun Kang, Motoko Omura, Akiko Suzuki, Chumpol Theeraladanon, Takashi Oka, Yoshihiro Nakagami, Atsushi Suzuki, Yoji Nagashima, Tomio Inoue
Pages: 471-475
Published online on: 01 May 2010

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Article

Effect of fibroblast growth factor-2 on dental pulp cells derived from human deciduous teeth in vitro

Tomokazu Hasegawa, Naoyuki Chosa, Takeyoshi Asakawa, Yoshitaka Yoshimura, Asami Asakawa, Akira Ishisaki, Mitsuro Tanaka
Pages: 477-480
Published online on: 01 May 2010

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Article

Consultation clinics for complementary and alternative medicine at Japanese university hospitals: An analysis at Tokushima University Hospital

Hiroaki Yanagawa, Junji Terao, Eiji Takeda, Yoshihisa Takaishi, Yoshiki Kashiwada, Kazuyoshi Kawazoe, Shuji Fushitani, Koichiro Tsuchiya, Aiko Yamauchi, Chiho Sato, Minoru Irahara
Pages: 481-483
Published online on: 01 May 2010

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Article

Effects of pre-operative transcatheter arterial chemoembolization for resectable hepatocellular carcinoma: Implication of circulating cancer cells by detection of α-fetoprotein mRNA

Masahiro Murakami, Hiroaki Nagano, Shogo Kobayashi, Hiroshi Wada, Masato Nakamura, Shigeru Marubashi, Hidetoshi Eguchi, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki, Masaki Mori
Pages: 485-491
Published online on: 01 May 2010

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Article

Correlation of granulin expression in intracranial meningiomas to clinical parameters

Choong H. Kim, Jin H. Cheong, Jae M. Kim
Pages: 493-496
Published online on: 01 May 2010

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Article

CD318/CUB-domain-containing protein 1 expression on cord blood hematopoietic progenitors

Hiromi Takeda, Yoshihiro Fujimori, Shunro Kai, Hiroyasu Ogawa, Takashi Nakano
Pages: 497-501
Published online on: 01 May 2010

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Article

Post mortem contrast-enhanced computed tomography in a case of sudden death from acute pulmonary thromboembolism

Kiyoshi Kikuchi, Ko-ichi Kawahara, Chiyoko Tsuji, Yutaka Tajima, Terukazu Kuramoto, Miwako Shihara, Yukari Koga, Naoto Shiomi, Hisaaki Uchikado, Yoko Morimoto, Naoki Miura, Kentaro Mera, Yoshiko Ohno, Naohisa Miyagi, Teruto Hashiguchi, Ikuro Maruyama, Naohumi Hayabuchi, Kenji Nakayama, Minoru Shigemori
Pages: 503-505
Published online on: 01 May 2010

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Article

Evaluation of serum iron levels during FOLFOX4 and FOLFIRI therapies

Satomi Mashiko, Isao Nagaoka, Masayuki Kitajima, Tomoo Watanabe, Kazuhiko Nishimura, Shunji Futagawa, Takumi Ochiai
Pages: 507-511
Published online on: 01 May 2010

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Article

Potentiation of the growth inhibition activity of 2-({4-[4-(acridin-9-ylamino)phenylthio]phenyl}(2-hydroxyethyl)amino)ethan-1-ol (CK0402) by Herceptin in SKBR-3 human breast cancer cells

Yuan-Wan Sun, Ting-Kuang Niu, Jin-Ming Yang, Chul-Hoon Kwon, Kuen-Yuan Chen, Kun-Ming Chen
Pages: 513-518
Published online on: 01 May 2010

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Article

Epigenetic activation of E-cadherin is a candidate therapeutic target in human hepatocellular carcinoma

Xuemei Qiu, Fengchang Qiao, Xianwei Su, Zhujiang Zhao, Hong Fan
Pages: 519-523
Published online on: 01 May 2010

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Article

Impact of human papillomavirus genotype on response to treatment and survival in patients receiving radiotherapy for squamous cell carcinoma of the cervix

Jannatul Ferdousi, Yutaka Nagai, Tsuyoshi Asato, Makoto Hirakawa, Morihiko Inamine, Wataru Kudaka, Ken-ichi Kariya, Yoichi Aoki
Pages: 525-530
Published online on: 01 May 2010

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Article

Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol

Pamela Cruz, Cristian Torres, María E. Ramírez, María J. Epuñán, Luis E. Valladares, Walter D. Sierralta
Pages: 531-536
Published online on: 01 May 2010

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Article

Improving gene transfer in human renal carcinoma cells: Utilization of adenovirus vectors containing chimeric type 5 and type 35 fiber proteins

Bishnu Acharya, Shuji Terao, Toru Suzuki, Michio Naoe, Katsuyuki Hamada, Hiroyuki Mizuguchi, Akinobu Gotoh
Pages: 537-540
Published online on: 01 May 2010

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Journal Cover
May-2026 Volume 31 Issue 5

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Impact Factor: 2.3

Review Open Access

FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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Article Open Access

A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Article

Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Article Open Access

Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Article Open Access

Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Review Open Access

Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Review Open Access

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Article Open Access

Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Review Open Access

Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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Retraction Open Access

[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Article Open Access

Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Article Open Access

Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Article

Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Article Open Access

Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article Open Access

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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Article Open Access

RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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Article Open Access

A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Impact Factor: 2.3

Article Open Access

Factors affecting central sensitization inventory score before surgery for distal radius fractures

Shoichiro Ishii, Kiyohito Naito, Norizumi Imazu, Takamaru Suzuki, Kenjiro Kawamura, So Kawakita, Tatsuki Itoh, Muneaki Ishijima
Article Number: 162
Published online on: 09 April 2026

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Article Open Access

Systemic immune‑inflammation index and neutrophil‑to‑lymphocyte ratio predict treatment responses in elderly patients with profound sudden deafness

Chong Li, Huili Wu, Hongxia Cui, Yue Li, Zhiming Sun, Siqi Haoliu, Xinfa Wei
Article Number: 161
Published online on: 09 April 2026

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Efficacy analysis of percutaneous cannulated paravertebral approach for microscopic resection of intraspinal schwannomas: A case series

Shaobo Yang, Nianhua Wang
Article Number: 160
Published online on: 09 April 2026

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Case Report Open Access

3D‑printed customized semi‑restrictive elbow prosthesis for severe pseudoarthritis following comminuted fractures of the distal humerus: A case report and review

Bo Zheng, Xiu-Li Zhang, Yu-Xiang Cheng, Ze-Bi He, Peng Li
Article Number: 159
Published online on: 09 April 2026

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α‑tocopherol in the prevention of ischemic or hemorrhagic stroke: A meta‑analysis

Peng Xu, Pengfei Cheng
Article Number: 158
Published online on: 09 April 2026

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Article Open Access

Preliminary study on symptoms and signs of patients with laryngopharyngeal reflux disease infected with Helicobacter pylori

Haixiang Zhang, Huanhuan Dang, Xin Wang, Yuxiang Zhao, Jinping Wang
Article Number: 157
Published online on: 09 April 2026

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Review Open Access

Autophagy‑epithelial‑mesenchymal transition crosstalk in acute respiratory distress syndrome: Mechanistic insights and therapeutic perspectives (Review)

Yue Zhang, Hongzhi He, Chufan Dong, Qing Guo, Jiuwen Tan, Yonggui Yang, Zhuangbo Guo, Rui Zhang
Article Number: 156
Published online on: 08 April 2026

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Review Open Access

Analysis of low‑benefit subgroups in breast‑conserving surgery: Implications for clinical decision‑making (Review)

Weicheng Lin, Lan Luo, Guiping Guo, Huan Lin
Article Number: 155
Published online on: 08 April 2026

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Case Report

Plexiform fibromyxoma of the lesser curvature of the stomach in a 16‑year‑old adolescent: A case report and literature review

Zhenhua Fu, Peiyao Tao, Da Sun, Xiang Chen
Article Number: 154
Published online on: 08 April 2026

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Case Report Open Access

Retroperitoneal ovarian venous hemangioma: A case report

Jie Tian, Hong Hu, Siyi Chen, Junping Li
Article Number: 153
Published online on: 08 April 2026

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Retraction Open Access

[Retracted] MicroRNA‑140‑5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3

Jiehua Zhu, Jianglin Wang, Jialin Huang, Wensheng Du, Yingzhong He, Hongfei Pan, Junmin Luo
Article Number: 152
Published online on: 07 April 2026

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Article Open Access

Effects of rok1 gene deletion on mitosis in fission yeast at appropriate and stressful temperatures and the molecular mechanisms

Jiayi He, Mengnan Liu, Jiani Xu, Xiang Ding, Yiling Hou
Article Number: 151
Published online on: 02 April 2026

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Review Open Access

Therapeutic potential of allicin against viral infections: Mechanisms and safety profile (Review)

Ming-Jun Yu, Yong Zhu, Wei Zhang, Qiao-Ping Xu, Hai-Ming Wang, Zhao Ma
Article Number: 150
Published online on: 02 April 2026

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Article Open Access

Interacting proteins of AMPK studied using TurboID proximity labeling technology

Xiaoshan Liu, Jieyu Guo, Qiongyao Wang, Wu Liu, Yan Xue, Shuang Guo, Miao Li
Article Number: 149
Published online on: 02 April 2026

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Article Open Access

Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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