|
1
|
Dienstag JL: Hepatitis B virus infection.
N Engl J Med. 359:1486–1500. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Seeger C and Mason WS: Hepatitis B virus
biology. Microbiol Mol Biol Rev. 64:51–68. 2000. View Article : Google Scholar
|
|
3
|
Murakami S: Hepatitis B virus X protein: a
multifunctional viral regulator. J Gastroenterol. 36:651–660. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Scaglioni PP, Melegari M and Wands JR:
Posttranscriptional regulation of hepatitis B virus replication by
the precore protein. J Virol. 71:345–353. 1997.PubMed/NCBI
|
|
5
|
Melegari M, Scaglioni PP and Wands JR:
Cloning and characterization of a novel hepatitis B virus x binding
protein that inhibits viral replication. J Virol. 72:1737–1743.
1998.PubMed/NCBI
|
|
6
|
Keasler VV, Hodgson AJ, Madden CR and
Slagle BL: Enhancement of hepatitis B virus replication by the
regulatory X protein in vitro and in vivo. J Virol. 81:2656–2662.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Bouchard MJ, Wang LH and Schneider RJ:
Calcium signaling by HBx protein in hepatitis B virus DNA
replication. Science. 294:2376–2378. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Tang H, Delgermaa L, Huang F, et al: The
transcriptional transactivation function of HBx protein is
important for its augmentation role in hepatitis B virus
replication. J Virol. 79:5548–5556. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Yang PL, Althage A, Chung J and Chisari
FV: Hydrodynamic injection of viral DNA: a mouse model of acute
hepatitis B virus infection. Proc Natl Acad Sci USA.
99:13825–13830. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Keasler VV, Hodgson AJ, Madden CR and
Slagle BL: Hepatitis B virus HBx protein localized to the nucleus
restores HBx-deficient virus replication in HepG2 cells and in vivo
in hydrodynamically-injected mice. Virology. 390:122–129. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Newbold JE, Xin H, Tencza M, Sherman G,
Dean J, Bowden S and Locarnini S: The covalently closed duplex form
of the hepadnavirus genome exists in situ as a heterogeneous
population of viral minichromosomes. J Virol. 69:3350–3357.
1995.PubMed/NCBI
|
|
12
|
Gao W and Hu J: Formation of hepatitis B
virus covalently closed circular DNA: removal of genome-linked
protein. J Virol. 81:6164–6174. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Levrero M, Pollicino T, Petersen J,
Belloni L, Raimondo G and Dandri M: Control of cccDNA function in
hepatitis B virus infection. J Hepatol. 51:581–592. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Bock CT, Schwinn S, Locarnini S, Fyfe J,
Manns MP, Trautwei C and Zentgraf H: Structural organization of the
hepatitis B virus minichromosome. J Mol Biol. 307:183–196. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Pollicino T, Belloni L, Raffa G, Pediconi
N, Squadrito G, Raimondo G and Levrero M: Hepatitis B virus
replication is regulated by the acetylation status of hepatitis B
virus cccDNA-bound H3 and H4 histones. Gastroenterology.
130:823–837. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Bouchard MJ, Wang L and Schneider RJ:
Activation of focal adhesion kinase by hepatitis B virus HBx
protein: multiple functions in viral replication. J Virol.
80:4406–4414. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Cougot D, Wu Y, Cairo S, et al: The
hepatitis B virus X protein functionally interacts with
CREB-binding protein/p300 in the regulation of CREB-mediated
transcription. J Biol Chem. 282:4277–4287. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Harju S, McQueen KJ and Peterson KR:
Chromatin structure and control of beta-like globin gene switching.
Exp Biol Med (Maywood). 227:683–700. 2002.PubMed/NCBI
|
|
19
|
Gong Q, Chen S, Guo J, et al: Chromosome
remodeling related to hepatitis B virus replication in HepG2 cells.
DNA Cell Biol. 30:347–354. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Slagle BL, Lee TH, Medina D, Finegold MJ
and Butel JS: Increased sensitivity to the hepatocarcinogen
diethylnitrosamine in transgenic mice carrying the hepatitis B
virus X gene. Mol Carcinog. 15:261–269. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Belloni L, Pollicino T, De Nicola F, et
al: Nuclear HBx binds the HBV minichromosome and modifies the
epigenetic regulation of cccDNA function. Proc Natl Acad Sci USA.
106:19975–19979. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Sambrook J and Russel DW: Molecular
Cloning: A Laboratory Manual. 3rd edition. Cold Spring Harbor
Laboratory Press; New York: pp. 138–140. pp. 151–153. 2001
|
|
23
|
Brechot C, Kremsdorf D, Soussan P, Pineau
P, Dejean A, Paterlini-Brechot P and Tiollais P: Hepatitis B virus
(HBV)-related hepatocellular carcinoma (HCC): molecular mechanisms
and novel paradigms. Pathol Biol (Paris). 58:278–287. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lucifora J, Arzberger S, Durantel D, et
al: Hepatitis B virus X protein is essential to initiate and
maintain virus replication after infection. J Hepatol. 55:996–1003.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Pollicino T, Squadrito G, Cerenzia G, et
al: Hepatitis B virus maintains its pro-oncogenic properties in the
case of occult HBV infection. Gastroenterology. 126:102–110. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Stoll-Becker S, Repp R, Glebe D, et al:
Transcription of hepatitis B virus in peripheral blood mononuclear
cells from persistently infected patients. J Virol. 71:5399–5407.
1997.PubMed/NCBI
|
|
27
|
Hake SB, Xiao A and Allis CD: Linking the
epigenetic ‘language’ of covalent histone modifications to cancer.
Br J Cancer. 90:761–769. 2004.
|
|
28
|
Strahl BD and Allis CD: The language of
covalent histone modifications. Nature. 403:41–45. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Dillon SC, Zhang X, Trievel RC and Cheng
X: The SET-domain protein superfamily: protein lysine
methyltransferases. Genome Biol. 6:2272005. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Hamamoto R, Furukawa Y, Morita M, et al:
SMYD3 encodes a histone methyltransferase involved in the
proliferation of cancer cells. Nat Cell Biol. 6:731–740. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Yang L, He J, Chen L and Wang G: Hepatitis
B virus X protein upregulates expression of SMYD3 and C-MYC in
HepG2 cells. Med Oncol. 26:445–451. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Park IY, Sohn BH, Yu E, et al: Aberrant
epigenetic modifications in hepatocarcinogenesis induced by
hepatitis B virus X protein. Gastroenterology. 132:1476–1494. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Rouleau J, MacLeod AR and Szyf M:
Regulation of the DNA methyltransferase by the Ras-AP-1 signaling
pathway. J Biol Chem. 270:1595–1601. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Peterson EJ, Bogler O and Taylor SM:
p53-mediated repression of DNA methyltransferase 1 expression by
specific DNA binding. Cancer Res. 63:6579–6582. 2003.PubMed/NCBI
|
|
35
|
Zheng DL, Zhang L, Cheng N, et al:
Epigenetic modification induced by hepatitis B virus X protein via
interaction with de novo DNA methyltransferase DNMT3A. J Hepatol.
50:377–387. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Melegari M, Wolf SK and Schneider RJ:
Hepatitis B virus DNA replication is coordinated by core protein
serine phosphorylation and HBx expression. J Virol. 79:9810–9820.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Chadee DN, Hendzel MJ, Tylipski CP, Allis
CD, Bazett-Jones DP, Wright JA and Davie JR: Increased Ser-10
phosphorylation of histone H3 in mitogen-stimulated and
oncogene-transformed mouse fibroblasts. J Biol Chem.
274:24914–24920. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Min L, He B and Hui L: Mitogen-activated
protein kinases in hepatocellular carcinoma development. Semin
Cancer Biol. 21:10–20. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Wang GG, Allis CD and Chi P: Chromatin
remodeling and cancer, Part I: Covalent histone modifications.
Trends Mol Med. 13:363–372. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Hirota T, Lipp JJ, Toh BH and Peters JM:
Histone H3 serine 10 phosphorylation by Aurora B causes HP1
dissociation from heterochromatin. Nature. 438:1176–1180. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Nowak SJ and Corces VG: Phosphorylation of
histone H3: a balancing act between chromosome condensation and
transcriptional activation. Trends Genet. 20:214–220. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Herceg Z and Paliwal A: Epigenetic
mechanisms in hepatocellular carcinoma: how environmental factors
influence the epigenome. Mutat Res. 727:55–61. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Shon JK, Shon BH, Park IY, et al:
Hepatitis B virus-X protein recruits histone deacetylase 1 to
repress insulin-like growth factor binding protein 3 transcription.
Virus Res. 139:14–21. 2009. View Article : Google Scholar : PubMed/NCBI
|
