|
1
|
Prusiner SB: Prions. Proc Natl Acad Sci
USA. 95:13363–13383. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Seo JS, Moon MH, Jeong JK, et al: SIRT1, a
histone deacetylase, regulates prion protein-induced neuronal cell
death. Neurobiol Aging. 33:1110–1120. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Seo JS, Seol JW, Moon MH, Jeong JK, Lee YJ
and Park SY: Hypoxia protects neuronal cells from human prion
protein fragment-induced apoptosis. J Neurochem. 112:715–722. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Watt NT, Taylor DR, Gillott A, Thomas DA,
Perera WSS and Hooper NM: Reactive oxygen species-mediated
beta-cleavage of the prion protein in the cellular response to
oxidative stress. J Biol Chem. 280:35914–35921. 2005. View Article : Google Scholar
|
|
5
|
Jeong JK, Seo JS, Moon MH, Lee YJ, Seol JW
and Park SY: Hypoxia-inducible factor-1 α regulates prion protein
expression to protect against neuron cell damage. Neurobiol Aging.
33:1006.e1–10. 2012.
|
|
6
|
Gray F, Chrétien F, Adle-Biassette H, et
al: Neuronal apoptosis in Creutzfeldt-Jakob disease. J Neuropathol
Exp Neurol. 58:321–328. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Liberski PP, Sikorska B,
Bratosiewicz-Wasik J, Gajdusek DC and Brown P: Neuronal cell death
in transmissible spongiform encephalopathies (prion diseases)
revisited: from apoptosis to autophagy. Int J Biochem Cell Biol.
36:2473–2490. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Forloni G, Angeretti N, Chiesa R, et al:
Neurotoxicity of a prion protein fragment. Nature. 362:543–546.
1993. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Brown DR, Schmidt B and Kretzschmar HA:
Role of microglia and host prion protein in neurotoxicity of a
prion protein fragment. Nature. 380:345–347. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Florio T, Thellung S, Amico C, et al:
Prion protein fragment 106-126 induces apoptotic cell death and
impairment of L-type voltage-sensitive calcium channel activity in
the GH3 cell line. J Neurosc Res. 54:341–352. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ettaiche M, Pichot R, Vincent J-P and
Chabry J: In vivo cytotoxicity of the prion protein fragment
106-126. J Biol Chem. 275:36487–36490. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Jeong JK, Moon MH, Lee YJ, Seol JW and
Park SY: Autophagy induced by the class III histone deacetylase
Sirt1 prevents prion peptide neurotoxicity. Neurobiol Aging.
34:146–156. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
O’Donovan CN, Tobin D and Cotter TG: Prion
protein fragment PrP-(106-126) induces apoptosis via mitochondrial
disruption in human neuronal SH-SY5Y cells. J Biol Chem.
276:43516–43523. 2001.PubMed/NCBI
|
|
14
|
Kiuchi M, Adachi K, Kohara T, et al:
Synthesis and immunosuppressive activity of 2-substituted
2-aminopropane-1,3-diols and 2-aminoethanols. J Med Chem.
43:2946–2961. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wei Y, Yemisci M, Kim HH, et al:
Fingolimod provides long-term protection in rodent models of
cerebral ischemia. Ann Neurol. 69:119–129. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kihara A and Igarashi Y: Production and
release of sphingosine 1-phosphate and the phosphorylated form of
the immunomodulator FTY720. Biochim Biophys Acta. 1781:496–502.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Stessin AM, Gursel DB, Schwartz A, et al:
FTY720, sphingosine 1-phosphate receptor modulator, selectively
radioprotects hippocampal neural stem cells. Neurosci Lett.
516:253–258. 2012. View Article : Google Scholar
|
|
18
|
Miron VE, Schubart A and Antel JP: Central
nervous system-directed effects of FTY720 (fingolimod). J Neurol
Sci. 274:13–17. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Harada J, Foley M, Moskowitz MA and Waeber
C: Sphingosine-1-phosphate induces proliferation and morphological
changes of neural progenitor cells. J Neurochem. 88:1026–1039.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chun J, Weiner JA, Fukushima N, et al:
Neurobiology of receptor-mediated lysophospholipid signaling. From
the first lysophospholipid receptor to roles in nervous system
function and development. Ann N Y Acad Sci. 905:110–117. 2000.
View Article : Google Scholar
|
|
21
|
Edsall LC, Pirianov GG and Spiegel S:
Involvement of sphingosine 1-phosphate in nerve growth
factor-mediated neuronal survival and differentiation. J Neurosci.
17:6952–6960. 1997.PubMed/NCBI
|
|
22
|
Jackson SJ, Giovannoni G and Baker D:
Fingolimod modulates microglial activation to augment markers of
remyelination. J Neuroinflammation. 8:762011. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Deogracias R, Klein C, Matsumoto T, et al:
Expression of brain-derived neurotrophic factor is regulated by
fingolimod (FTY720) in cultured neurons. Mult Scler.
14:S2432008.
|
|
24
|
Brinkmann V, Cyster JG and Hla T: FTY720:
sphingosine 1-phosphate receptor-1 in the control of lymphocyte
egress and endothelial barrier function. Am J Transplant.
4:1019–1025. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Valentine WJ, Kiss GN, Liu J, et al:
(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive
agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR
signaling and inhibits autotaxin activity. Cell Signal.
22:1543–1553. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Tournier C, Hess P, Yang DD, et al:
Requirement of JNK for stress-induced activation of the cytochrome
c-mediated death pathway. Science. 288:870–874. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Tsuruta F, Sunayama J, Mori Y, et al: JNK
promotes Bax translocation to mitochondria through phosphorylation
of 14-3-3 proteins. EMBO J. 23:1889–1899. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Ehling R, Berger T and Reindl M: Multiple
sclerosis - established and novel therapeutic approaches. Cent Nerv
Syst Agents Med Chem. 10:3–15. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Gonzalez-Cabrera PJ, Cahalan SM, Nguyen N,
et al: S1P(1) receptor modulation with cyclical recovery from
lymphopenia ameliorates mouse model of multiple sclerosis. Mol
Pharmacol. 81:166–174. 2012.
|
|
30
|
Kim HJ, Miron VE, Dukala D, et al:
Neurobiological effects of sphingosine 1-phosphate receptor
modulation in the cuprizone model. FASEB J. 25:1509–1518. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lin MT and Beal MF: Mitochondrial
dysfunction and oxidative stress in neurodegenerative diseases.
Nature. 443:787–795. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Jeong JK, Moon MH, Lee YJ, Seol JW and
Park SY: Melatonin-induced autophagy protects against human prion
protein-mediated neurotoxicity. J Pineal Res. 53:138–146. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Schroeter H, Boyd CS, Ahmed R, et al:
c-Jun N-terminal kinase (JNK)-mediated modulation of brain
mitochondria function: new target proteins for JNK signalling in
mitochondrion-dependent apoptosis. Biochem J. 372:359–369. 2003.
View Article : Google Scholar
|
