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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2013 Volume 32 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Biochemical basis of cancer chemoprevention and/or chemotherapy with ginsenosides (Review)

Joon-Seok Choi, Kyung-Soo Chun, Juthika Kundu, Joydeb Kumar Kundu
Pages: 1227-1238
Published online on: 10 October 2013

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Review

The role of the CXCL12-CXCR4/CXCR7 axis in the progression and metastasis of bone sarcomas (Review)

Yu-Xin Liao, Cheng-Hao Zhou, Hui Zeng, Dong-Qing Zuo, Zhuo‑Ying Wang, Fei Yin, Ying-Qing Hua, Zheng-Dong Cai
Pages: 1239-1246
Published online on: 11 October 2013

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Review

cMET as a potential therapeutic target in gastric cancer (Review)

Lisong Teng, Jun Lu
Pages: 1247-1254
Published online on: 18 October 2013

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Article Open Access

Effects of apatite particle size in two apatite/collagen composites on the osteogenic differentiation profile of osteoblastic cells

Wataru Hatakeyama, Masayuki Taira, Naoyuki Chosa, Hidemichi Kihara, Akira Ishisaki, Hisatomo Kondo
Pages: 1255-1261
Published online on: 02 October 2013

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Article Open Access

Bone marrow-derived mesenchymal stem cells protect against cisplatin-induced acute kidney injury in rats by inhibiting cell apoptosis

Shaohua Qi, Dongcheng Wu
Pages: 1262-1272
Published online on: 08 October 2013

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Article

Chlorogenic acid alters the biological characteristics of basophil granulocytes by affecting the fluidity of the cell membrane and triggering pseudoallergic reactions

Qin Li, Yin Zhao, Xiaoliang Zheng, Qiuhong Chen, Xinyue Zhang
Pages: 1273-1280
Published online on: 24 September 2013

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Article

GuaLou GuiZhi decoction inhibits LPS-induced microglial cell motility through the MAPK signaling pathway

Haixia Hu, Zuanfang Li, Xiaoqin Zhu, Ruhui Lin, Jun Peng, Jing Tao, Lidian Chen
Pages: 1281-1286
Published online on: 11 October 2013

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Article

Differential expression of rat hippocampal microRNAs in two rat models of chronic pain

Yoko Hori, Gentaro Goto, Masae Arai-Iwasaki, Masashi Ishikawa, Atsuhiro Sakamoto
Pages: 1287-1292
Published online on: 24 September 2013

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Article

Metformin decreases high-fat diet-induced renal injury by regulating the expression of adipokines and the renal AMP-activated protein kinase/acetyl-CoA carboxylase pathway in mice

Dal Kim, Jung Eun Lee, Yu Jin Jung, Ae Sin Lee, Sik Lee, Sung Kwang Park, Suhn Hee Kim, Byung-Hyun Park, Won Kim, Kyung Pyo Kang
Pages: 1293-1302
Published online on: 25 September 2013

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Article

Effects of electroacupuncture on apoptotic pathways in a rat model of focal cerebral ischemia

Yu Ri Kim, Ha Neui Kim, Ji Yeon Jang, Cheol Park, Jun Hyuk Lee, Hwa Kyoung Shin, Yung Hyun Choi, Byung Tae Choi
Pages: 1303-1310
Published online on: 27 September 2013

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Article

The dual role of autophagy in chondrocyte responses in the pathogenesis of articular cartilage degeneration in osteoarthritis

Jun Chang, Wei Wang, Hui Zhang, Yong Hu, Mingli Wang, Zongsheng Yin
Pages: 1311-1318
Published online on: 11 October 2013

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Article

Probiotic-fermented purple sweet potato yogurt activates compensatory IGF‑IR/PI3K/Akt survival pathways and attenuates cardiac apoptosis in the hearts of spontaneously hypertensive rats

Pei-Pei Lin, You-Miin Hsieh, Wei-Wen Kuo, Yueh-Min Lin, Yu-Lan Yeh, Chien-Chung Lin, Fuu-Jen Tsai, Chang-Hai Tsai, Chih-Yang Huang, Cheng-Chih Tsai
Pages: 1319-1328
Published online on: 11 October 2013

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Article

Bauhinia championi (Benth.) Benth. polysaccharides upregulate Wnt/β-catenin signaling in chondrocytes

Huiting Li, Xihai Li, Guozhong Liu, Jiashou Chen, Xiaping Weng, Fayuan Liu, Huifeng Xu, Xianxiang Liu, Hongzhi Ye
Pages: 1329-1336
Published online on: 14 October 2013

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Article

Study on the interactions between transplanted bone marrow-derived mesenchymal stem cells and regulatory T cells for the treatment of experimental colitis

Dongmei Zuo, Xingxing Liu, Zhexing Shou, Heng Fan, Qing Tang, Xueyun Duan, Dan Cao, Zhou Zou, Lijuan Zhang
Pages: 1337-1344
Published online on: 16 October 2013

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Article

Oridonin exerts protective effects against hydrogen peroxide‑induced damage by altering microRNA expression profiles in human dermal fibroblasts

Eun-Jin Lee, Hwa Jun Cha, Kyu Joong Ahn, In‑Sook  An, Sungkwan An, Seunghee Bae
Pages: 1345-1354
Published online on: 22 October 2013

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Article

The in vitro and in vivo treatment effects of overexpressed lentiviral vector-mediated human BMP2 gene in the femoral bone marrow stromal cells of osteoporotic rats

Bing Zhao, Qiang Wang, Tianzun Tao, Juan Li, Qingyuan Lin
Pages: 1355-1365
Published online on: 25 September 2013

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Article

Potential therapeutic value of dendritic cells loaded with NY‑ESO‑1 protein for the immunotherapy of advanced hepatocellular carcinoma

Yuqing Chen, Aimin Huang, Meiqin Gao, Yongqin Yan, Wenmin Zhang
Pages: 1366-1372
Published online on: 27 September 2013

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Article

Silencing HCCR2 expression inhibits the proliferation of leukemia cells by inducing apoptosis and promoting cell cycle arrest

Shu-Kai Qiao, Han-Yun Ren, Yong-Jin Shi, Wei Liu
Pages: 1373-1379
Published online on: 08 October 2013

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Article

Silencing of angiotensin‑converting enzyme by RNA interference prevents H9c2 cardiomyocytes from apoptosis induced by anoxia/reoxygenation through regulation of the intracellular renin-angiotensin system

Weiguo Wan, Xuejun Jiang, Xiaoyan Li, Cui Zhang, Xin Yi
Pages: 1380-1386
Published online on: 11 October 2013

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Article

FTY720 protects neuronal cells from damage induced by human prion protein by inactivating the JNK pathway

Myung-Hee Moon, Jae-Kyo Jeong, You-Jin Lee, Sang-Youel Park
Pages: 1387-1393
Published online on: 16 October 2013

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Article

Vitamin D binding protein plays an important role in the progression of endometriosis

Jin-Hee Hwang, Tao Wang, Kyu-Sup Lee, Jong-Kil Joo, Hong-Gu Lee
Pages: 1394-1400
Published online on: 24 September 2013

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Article

Palmitate induces autophagy in pancreatic β-cells via endoplasmic reticulum stress and its downstream JNK pathway

Ying-Ying Chen, Lian-Qing Sun, Bao-An Wang, Xiao-Man Zou, Yi-Ming Mu, Ju-Ming Lu
Pages: 1401-1406
Published online on: 18 October 2013

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Article

Low doses of ionizing radiation induce immune-stimulatory responses in isolated human primary monocytes

Houssein El-Saghire, Arlette Michaux, Hubert Thierens, Sarah Baatout
Pages: 1407-1414
Published online on: 30 September 2013

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Article

Detection and genome analysis of human bocavirus 1-4 from hospitalized children with acute lower respiratory tract infection and symptoms of wheezing in Shanghai

Jun Shen, Qirong Zhu, Mei Zeng, Hui Yu
Pages: 1415-1420
Published online on: 30 September 2013

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Article

Proteomic analysis of aqueous humor from patients with branch retinal vein occlusion-induced macular edema

Jiaqi Yao, Zhijun Chen, Qin Yang, Xiaoyi Liu, Xi Chen, Min Zhuang, Qinghuai Liu
Pages: 1421-1434
Published online on: 25 September 2013

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Article

Cystometric parameters and the activity of signaling proteins in association with the compensation or decompensation of bladder function in an animal experimental model of partial bladder outlet obstruction

Bo-Hwa Choi, Long-Hu Jin, Khae-Hawn Kim, Sung-An Kang, Ju-Hee Kang, Sang-Min Yoon, Chang-Shin Park, Tack Lee
Pages: 1435-1441
Published online on: 30 September 2013

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Article

ox-LDL downregulates eNOS activity via LOX-1-mediated endoplasmic reticulum stress

Jie Zhou, Morad Dirhem Naji Abid, Yufang Xiong, Qing Chen, Juan Chen
Pages: 1442-1450
Published online on: 30 September 2013

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Article

Expression and purification of a human anti-cyclin D1 single-chain variable fragment antibody AD5 and its characterization

Yan Wu, Desheng Zou, Yuhua Cao, Nannan Yao, Junye Wang, Wenhan Wang, Hongyu Jiang, Guiying Li
Pages: 1451-1457
Published online on: 11 October 2013

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Article

The WWOX tumor suppressor gene in endometrial adenocarcinoma

Elżbieta Płuciennik, Katarzyna Kośla, Katarzyna Wójcik-Krowiranda, Andrzej Bieńkiewicz, Andrzej K. Bednarek
Pages: 1458-1464
Published online on: 11 October 2013

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Article

H. pylori infection-induced MSC differentiation into CAFs promotes epithelial-mesenchymal transition in gastric epithelial cells

Qiang Zhang, Mei Wang, Feng Huang, Tingting Yang, Jie Cai, Xu Zhang, Wei Zhu, Hui Qian, Wenrong Xu
Pages: 1465-1473
Published online on: 22 October 2013

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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