|
1
|
Walter DH, Rittig K, Bahlmann FH, et al:
Statin therapy accelerates reendothelialization: a novel effect
involving mobilization and incorporation of bone marrow-derived
endothelial progenitor cells. Circulation. 105:3017–3024. 2002.
View Article : Google Scholar
|
|
2
|
He T, Smith LA, Harrington S, Nath KA,
Caplice NM and Katusic ZS: Transplantation of circulating
endothelial progenitor cells restores endothelial function of
denuded rabbit carotid arteries. Stroke. 35:2378–2384. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Werner N, Junk S, Laufs U, et al:
Intravenous transfusion of endothelial progenitor cells reduces
neointima formation after vascular injury. Circ Res. 93:e17–e24.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Li DW, Liu ZQ, Wei J, Liu Y and Hu LS:
Contribution of endothelial progenitor cells to neovascularization
(Review). Int J Mol Med. 30:1000–1006. 2012.PubMed/NCBI
|
|
5
|
Hafizi S and Dahlback B: Gas6 and protein
S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase
subfamily. FEBS J. 273:5231–5244. 2006.PubMed/NCBI
|
|
6
|
Stitt TN, Conn G, Gore M, et al: The
anticoagulation factor protein S and its relative, Gas6, are
ligands for the Tyro 3/Axl family of receptor tyrosine kinases.
Cell. 80:661–670. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Schneider C, King RM and Philipson L:
Genes specifically expressed at growth arrest of mammalian cells.
Cell. 54:787–793. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Melaragno MG, Cavet ME, Yan C, et al: Gas6
inhibits apoptosis in vascular smooth muscle: role of Axl kinase
and Akt. J Mol Cell Cardiol. 37:881–887. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Stenhoff J, Dahlback B and Hafizi S:
Vitamin K-dependent Gas6 activates ERK kinase and stimulates growth
of cardiac fibroblasts. Biochem Biophys Res Commun. 319:871–878.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
McCloskey P, Fridell YW, Attar E, et al:
GAS6 mediates adhesion of cells expressing the receptor tyrosine
kinase Axl. J Biol Chem. 272:23285–23291. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Nakano T, Higashino K, Kikuchi N, et al:
Vascular smooth muscle cell-derived, Gla-containing
growth-potentiating factor for Ca(2+)-mobilizing growth factors. J
Biol Chem. 270:5702–5705. 1995.PubMed/NCBI
|
|
12
|
Melaragno MG, Wuthrich DA, Poppa V, et al:
Increased expression of Axl tyrosine kinase after vascular injury
and regulation by G protein-coupled receptor agonists in rats. Circ
Res. 83:697–704. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
O’Donnell K, Harkes IC, Dougherty L and
Wicks IP: Expression of receptor tyrosine kinase Axl and its ligand
Gas6 in rheumatoid arthritis: evidence for a novel endothelial cell
survival pathway. Am J Pathol. 154:1171–1180. 1999.PubMed/NCBI
|
|
14
|
Hasanbasic I, Cuerquis J, Varnum B and
Blostein MD: Intracellular signaling pathways involved in
Gas6-Axl-mediated survival of endothelial cells. Am J Physiol Heart
Circ Physiol. 287:H1207–H1213. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
D’Arcangelo D, Gaetano C and Capogrossi
MC: Acidification prevents endothelial cell apoptosis by Axl
activation. Circ Res. 91:e4–e12. 2002.PubMed/NCBI
|
|
16
|
Hasanbasic I, Rajotte I and Blostein M:
The role of gamma-carboxylation in the anti-apoptotic function of
gas6. J Thromb Haemost. 3:2790–2797. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ruan GX and Kazlauskas A: Axl is essential
for VEGF-A-dependent activation of PI3K/Akt. Embo J. 31:1692–1703.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Alciato F, Sainaghi PP, Sola D, Castello L
and Avanzi GC: TNF-alpha, IL-6, and IL-1 expression is inhibited by
GAS6 in monocytes/macrophages. J Leukoc Biol. 87:869–875. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ganopolsky JG, Abid MR, Aird WC and
Blostein MD: GAS6-induced signaling in human endothelial cells is
mediated by FOXO1a. J Thromb Haemost. 6:1804–1811. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kawasaki K, Watabe T, Sase H, et al: Ras
signaling directs endothelial specification of VEGFR2(+) vascular
progenitor cells. J Cell Biol. 181:131–141. 2008.PubMed/NCBI
|
|
21
|
Xu J, Liu X, Jiang Y, et al: MAPK/ERK
signalling mediates VEGF-induced bone marrow stem cell
differentiation into endothelial cell. J Cell Mol Med.
12:2395–2406. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yan X, Cai S, Xiong X, et al: Chemokine
receptor CXCR7 mediates human endothelial progenitor cells
survival, angiogenesis, but not proliferation. J Cell Biochem.
113:1437–1446. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Wang F, Wang Y, Zhang L and Zou L: Gene
modification with integrin-linked kinase improves function of
endothelial progenitor cells in pre-eclampsia in vitro. J Cell
Biochem. 112:3103–3111. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kalka C, Masuda H, Takahashi T, et al:
Transplantation of ex vivo expanded endothelial progenitor cells
for therapeutic neovascularization. Proc Natl Acad Sci USA.
97:3422–3427. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kawamoto A, Tkebuchava T, Yamaguchi J, et
al: Intramyocardial transplantation of autologous endothelial
progenitor cells for therapeutic neovascularization of myocardial
ischemia. Circulation. 107:461–468. 2003. View Article : Google Scholar
|
|
26
|
Nakano T, Kawamoto K, Kishino J, Nomura K,
Higashino K and Arita H: Requirement of gamma-carboxyglutamic acid
residues for the biological activity of Gas6: contribution of
endogenous Gas6 to the proliferation of vascular smooth muscle
cells. Biochem J. 323:387–392. 1997.PubMed/NCBI
|
|
27
|
Yanagita M, Arai H, Nakano T, et al: Gas6
induces mesangial cell proliferation via latent transcription
factor STAT3. J Biol Chem. 276:42364–42369. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Bellosta P, Zhang Q, Goff SP and Basilico
C: Signaling through the ARK tyrosine kinase receptor protects from
apoptosis in the absence of growth stimulation. Oncogene.
15:2387–2397. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Goruppi S, Ruaro E, Varnum B and Schneider
C: Gas6-mediated survival in NIH3T3 cells activates stress
signalling cascade and is independent of Ras. Oncogene.
18:4224–4236. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Allen MP, Linseman DA, Udo H, et al: Novel
mechanism for gonadotropin-releasing hormone neuronal migration
involving Gas6/Ark signaling to p38 mitogen-activated protein
kinase. Mol Cell Biol. 22:599–613. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Fridell YW, Villa JJ, Attar EC and Liu ET:
GAS6 induces Axl-mediated chemotaxis of vascular smooth muscle
cells. J Biol Chem. 273:7123–7126. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Angelillo-Scherrer A, de Frutos P,
Aparicio C, et al: Deficiency or inhibition of Gas6 causes platelet
dysfunction and protects mice against thrombosis. Nat Med.
7:215–221. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
33
|
Jiang L, Liu CY, Yang QF, Wang P and Zhang
W: Plasma level of growth arrest-specific 6 (GAS6) protein and
genetic variations in the GAS6 gene in patients with acute coronary
syndrome. Am J Clin Pathol. 131:738–743. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Holland SJ, Powell MJ, Franci C, et al:
Multiple roles for the receptor tyrosine kinase axl in tumor
formation. Cancer Res. 65:9294–9303. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Gallicchio M, Mitola S, Valdembri D, et
al: Inhibition of vascular endothelial growth factor receptor
2-mediated endothelial cell activation by Axl tyrosine kinase
receptor. Blood. 105:1970–1976. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Li Y, Ye X, Tan C, et al: Axl as a
potential therapeutic target in cancer: role of Axl in tumor
growth, metastasis and angiogenesis. Oncogene. 28:3442–3455. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Ruan GX and Kazlauskas A: Lactate engages
receptor tyrosine kinases axl, tie2, and vascular endothelial
growth factor receptor 2 to activate phosphoinositide 3-kinase/akt
and promote angiogenesis. J Biol Chem. 288:21161–21172. 2013.
View Article : Google Scholar
|
|
38
|
Allen MP, Zeng C, Schneider K, et al:
Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark)
signaling promotes gonadotropin-releasing hormone neuronal survival
via extracellular signal-regulated kinase (ERK) and Akt. Mol
Endocrinol. 13:191–201. 1999. View Article : Google Scholar
|
|
39
|
Shankar SL, O’Guin K, Cammer M, et al: The
growth arrest-specific gene product Gas6 promotes the survival of
human oligodendrocytes via a phosphatidylinositol
3-kinase-dependent pathway. J Neurosci. 23:4208–4218.
2003.PubMed/NCBI
|
|
40
|
Wang JY, Lee YT, Chang PF and Chau LY:
Hemin promotes proliferation and differentiation of endothelial
progenitor cells via activation of AKT and ERK. J Cell Physiol.
219:617–625. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Munoz-Chapuli R, Quesada AR and Angel MM:
Angiogenesis and signal transduction in endothelial cells. Cell Mol
Life Sci. 61:2224–2243. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Park IK, Giovenzana C, Hughes TL, Yu J,
Trotta R and Caligiuri MA: The Axl/Gas6 pathway is required for
optimal cytokine signaling during human natural killer cell
development. Blood. 113:2470–2477. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Angelillo-Scherrer A, Burnier L,
Lambrechts D, et al: Role of Gas6 in erythropoiesis and anemia in
mice. J Clin Invest. 118:583–596. 2008.PubMed/NCBI
|
|
44
|
Chao H and Hirschi KK: Hemato-vascular
origins of endothelial progenitor cells? Microvasc Res. 79:169–173.
2010. View Article : Google Scholar : PubMed/NCBI
|
