|
1
|
Vasu VT, Cross CE and Gohil K: Nr1d1, an
important circadian pathway regulatory gene, is suppressed by
cigarette smoke in murine lungs. Integr Cancer Ther. 8:321–328.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Kim H, Xu GL, Borczuk AC, et al: The
heparan sulfate proteoglycan GPC3 is a potential lung tumor
suppressor. Am J Respir Cell Mol Biol. 29:694–701. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Yuan BZ, Jefferson AM, Baldwin KT,
Thorgeirsson SS, Popescu NC and Reynolds SH: DLC-1 operates as a
tumor suppressor gene in human non-small cell lung carcinomas.
Oncogene. 23:1405–1411. 2004.PubMed/NCBI
|
|
4
|
Georgiou E, Valeri R, Tzimagiorgis G, et
al: Aberrant p16 promoter methylation among Greek lung cancer
patients and smokers: correlation with smoking. Eur J Cancer Prev.
16:396–402. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kim JS, Kim H, Shim YM, Han J, Park J and
Kim DH: Aberrant methylation of the FHIT gene in chronic smokers
with early stage squamous cell carcinoma of the lung.
Carcinogenesis. 25:2165–2171. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Tummala R, Romano RA, Fuchs E and Sinha S:
Molecular cloning and characterization of AP-2 epsilon, a fifth
member of the AP-2 family. Gene. 321:93–102. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Li H, Goswami PC and Domann FE: AP-2gamma
induces p21 expression, arrests cell cycle, and inhibits the tumor
growth of human carcinoma cells. Neoplasia. 8:568–577.
2006.PubMed/NCBI
|
|
8
|
Pellikainen J, Naukkarinen A, Ropponen K,
et al: Expression of HER2 and its association with AP-2 in breast
cancer. Eur J Cancer. 40:1485–1495. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Wajapeyee N, Britto R, Ravishankar HM and
Somasundaram K: Apoptosis induction by activator protein 2alpha
involves transcriptional repression of Bcl-2. J Biol Chem.
281:16207–16219. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Jean D, Gershenwald JE, Huang S, Luca M,
Hudson MJ, Tainsky MA and Bar-Eli M: Loss of AP-2 results in
up-regulation of MCAM/MUC18 and an increase in tumor growth and
metastasis of human melanoma cells. J Biol Chem. 273:16501–16508.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Karjalainen JM, Kellokoski JK, Eskelinen
MJ, Alhava EM and Kosma VM: Downregulation of transcription factor
AP-2 predicts poor survival in stage I cutaneous malignant
melanoma. J Clin Oncol. 16:3584–3591. 1998.PubMed/NCBI
|
|
12
|
Guo IC, Hu MC and Chung BC:
Transcriptional regulation of CYP11A1. J Biomed Sci. 10:593–598.
2003.PubMed/NCBI
|
|
13
|
Pena P, Reutens AT, Albanese C, et al:
Activator protein-2 mediates transcriptional activation of the
CYP11A1 gene by interaction with Sp1 rather than binding to DNA.
Mol Endocrinol. 13:1402–1416. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Sun X, Ritzenthaler JD, Zhong X, Zheng Y,
Roman J and Han S: Nicotine stimulates PPARbeta/delta expression in
human lung carcinoma cells through activation of PI3K/mTOR and
suppression of AP-2alpha. Cancer Res. 69:6445–6453. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Yuan J, Ma J, Zheng H, et al:
Overexpression of OLC1, cigarette smoke, and human lung
tumorigenesis. J Natl Cancer Inst. 100:1592–1605. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Cheng YH and Handwerger S: Identification
of an enhancer of the human activating protein-2alpha gene that
contains a critical Ets1 binding site. J Clin Endocrinol Metab.
88:3305–3311. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Hoffmann D, Hoffmann I and El-Bayoumy K:
The less harmful cigarette: a controversial issue. a tribute to
Ernst L Wynder. Chem Res Toxicol. 14:767–790. 2001.PubMed/NCBI
|
|
18
|
Feng Z, Hu W, Hu Y and Tang MS: Acrolein
is a major cigarette-related lung cancer agent: preferential
binding at p53 mutational hotspots and inhibition of DNA repair.
Proc Natl Acad Sci USA. 103:15404–15409. 2006. View Article : Google Scholar
|
|
19
|
Pfeifer GP, Denissenko MF and Tang M: p53
mutations, benzo[a]pyrene and lung cancer: a reply. Mutagenesis.
13:537–538. 1998.
|
|
20
|
Hecht SS, Carmella SG, Murphy SE, Foiles
PG and Chung FL: Carcinogen biomarkers related to smoking and upper
aerodigestive tract cancer. J Cell Biochem Suppl. 17F:27–35. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Smith LE, Denissenko MF, Bennett WP, Li H,
Amin S, Tang M and Pfeifer GP: Targeting of lung cancer mutational
hotspots by polycyclic aromatic hydrocarbons. J Natl Cancer Inst.
92:803–811. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Spira A, Beane J, Shah V, et al: Effects
of cigarette smoke on the human airway epithelial cell
transcriptome. Proc Natl Acad Sci USA. 101:10143–10148. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chari R, Lonergan KM, Ng RT, MacAulay C,
Lam WL and Lam S: Effect of active smoking on the human bronchial
epithelium transcriptome. BMC Genomics. 8:2972009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Gee JM, Robertson JF, Ellis IO, Nicholson
RI and Hurst HC: Immunohistochemical analysis reveals a tumour
suppressor-like role for the transcription factor AP-2 in invasive
breast cancer. J Pathol. 189:514–520. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Nyormoi O and Bar-Eli M: Transcriptional
regulation of metastasis-related genes in human melanoma. Clin Exp
Metastasis. 20:251–263. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ruiz M, Pettaway C, Song R, Stoeltzing O,
Ellis L and Bar-Eli M: Activator protein 2alpha inhibits
tumorigenicity and represses vascular endothelial growth factor
transcription in prostate cancer cells. Cancer Res. 64:631–638.
2004. View Article : Google Scholar
|
|
27
|
Liu R, Zhou A, Ren D, et al: Transcription
factor specificity protein 1 (SP1) and activating protein 2alpha
(AP-2alpha) regulate expression of human KCTD10 gene by binding to
proximal region of promoter. FEBS J. 276:1114–1124. 2009.
View Article : Google Scholar
|
|
28
|
Hilger-Eversheim K, Moser M, Schorle H and
Buettner R: Regulatory roles of AP-2 transcription factors in
vertebrate development, apoptosis and cell-cycle control. Gene.
260:1–12. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Zhang G and Veldhuis JD: Requirement for
proximal putative Sp1 and AP-2 cis-deoxyribonucleic acid elements
in mediating basal and luteinizing hormone- and insulin-dependent
in vitro transcriptional activation of the CYP17 gene in porcine
theca cells. Endocrinology. 145:2760–2766. 2004. View Article : Google Scholar
|
|
30
|
Bennett KL, Romigh T and Eng C: AP-2alpha
induces epigenetic silencing of tumor suppressive genes and
microsatellite instability in head and neck squamous cell
carcinoma. PLoS One. 4:e69312009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Taylor KH, Pena-Hernandez KE, Davis JW, et
al: Large-scale CpG methylation analysis identifies novel candidate
genes and reveals methylation hotspots in acute lymphoblastic
leukemia. Cancer Res. 67:2617–2625. 2007. View Article : Google Scholar
|
|
32
|
Imhof A, Schuierer M, Werner O, Moser M,
Roth C, Bauer R and Buettner R: Transcriptional regulation of the
AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/egr-related
zinc finger repressor. Mol Cell Biol. 19:194–204. 1999.PubMed/NCBI
|
|
33
|
Bauer R, Imhof A, Pscherer A, et al: The
genomic structure of the human AP-2 transcription factor. Nucleic
Acids Res. 22:1413–1420. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Li M, Wang Y, Hung MC and Kannan P:
Inefficient proteasomal-degradation pathway stabilizes AP-2alpha
and activates HER-2/neu gene in breast cancer. Int J Cancer.
118:802–811. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Li H, Watts GS, Oshiro MM, Futscher BW and
Domann FE: AP-2alpha and AP-2gamma are transcriptional targets of
p53 in human breast carcinoma cells. Oncogene. 25:5405–5415. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Stabach PR, Thiyagarajan MM, Woodfield GW
and Weigel RJ: AP2alpha alters the transcriptional activity and
stability of p53. Oncogene. 25:2148–2159. 2006. View Article : Google Scholar : PubMed/NCBI
|
