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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2014 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

MicroRNAs regulate vascular smooth muscle cell functions in atherosclerosis (Review)

Xin Yu, Zheng Li
Pages: 923-933
Published online on: 15 July 2014

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Review

Atherosclerosis and tumor suppressor molecules (Review)

Miho Suzuki, Akari Minami, Atsuko Nakanishi, Keiko Kobayashi, Satoru Matsuda, Yasunori Ogura, Yasuko Kitagishi
Pages: 934-940
Published online on: 25 July 2014

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Article Open Access

Cold atmospheric plasma treatment selectively targets head and neck squamous cell carcinoma cells

Rafael Guerrero-Preston, Takenori Ogawa, Mamoru Uemura, Gary Shumulinsky, Blanca L. Valle, Francesca Pirini, Rajani Ravi, David Sidransky, Michael Keidar, Barry Trink
Pages: 941-946
Published online on: 11 July 2014

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Article Open Access

Plasma proteomic changes during hypothermic and normothermic cardiopulmonary bypass in aortic surgeries

Teiji Oda, Akane Yamaguchi, Masao Yokoyama, Koji Shimizu, Kosaku Toyota, Tetsuro Nikai, Ken‑Ichi Matsumoto
Pages: 947-956
Published online on: 15 July 2014

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Article Open Access

Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis

Zhigang Cheng, Ling Li, Xueying Mo, Lu Zhang, Yongqiu Xie, Qulian Guo, Yunjiao Wang
Pages: 957-966
Published online on: 31 July 2014

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Article Open Access

Stomach antral endocrine cells in patients with irritable bowel syndrome

Magdy El-Salhy, Odd Helge Gilja, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 967-974
Published online on: 08 August 2014

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Article Open Access

Identification and association of the single nucleotide polymorphisms, C-509T, C+466T and T+869C, of the TGF-β1 gene in patients with asthma and their influence on the mRNA expression level of TGF-β1

Michał Panek, Tadeusz Pietras, Artur Fabijan, Jan Zioło, Łukasz Wieteska, Beata Małachowska, Wojciech Fendler, Janusz Szemraj, Piotr Kuna
Pages: 975-986
Published online on: 11 August 2014

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Article Open Access

Bone mesenchymal stem cell transplantation via four routes for the treatment of acute liver failure in rats

Lihua Sun, Xiaotang Fan, Lijuan Zhang, Guixiu Shi, Maimaiti Aili, Xiaobo Lu, Tao Jiang, Yuexin Zhang
Pages: 987-996
Published online on: 11 August 2014

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Article Open Access

Isolation, culture and phenotypic characterization of human sweat gland epithelial cells

Yunhe Gao, Meiying Li, Xueyan Zhang, Tingting Bai, Guanfan Chi, Jin Yu Liu, Yulin Li
Pages: 997-1003
Published online on: 14 July 2014

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Article Open Access

Proliferation and odontogenic differentiation of BMP2 gene‑transfected stem cells from human tooth apical papilla: An in vitro study

Wen Zhang, Xiaolei Zhang, Junqi Ling, Wei Liu, Xinchun  Zhang, Jinglei Ma, Jianmao Zheng
Pages: 1004-1012
Published online on: 24 July 2014

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Article Open Access

Curcumin inhibits human retinal pigment epithelial cell proliferation

Yun Sun, Zhi-Peng You
Pages: 1013-1019
Published online on: 23 July 2014

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Article

Inhibition by caffeic acid of the influenza A virus multiplication in vitro

Hirotoshi Utsunomiya, Masao Ichinose, Keiko Ikeda, Misao Uozaki, Junko Morishita, Tomomi Kuwahara, A. Hajime Koyama, Hisashi Yamasaki
Pages: 1020-1024
Published online on: 22 July 2014

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Article

Quercetin protects against high glucose-induced damage in bone marrow-derived endothelial progenitor cells

Li-Rong Zhao, Yu-Jun Du, Lei Chen, Zhi-Gang Liu, Yue-Hai Pan, Jian-Feng Liu, Bin Liu
Pages: 1025-1031
Published online on: 14 July 2014

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Article

Dexmedetomidine suppresses interleukin-1β-induced interleukin-6 synthesis in rat glial cells

Kumiko Tanabe, Rie Matsushima-Nishiwaki, Osamu Kozawa, Hiroki Iida
Pages: 1032-1038
Published online on: 24 July 2014

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Article

Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced inflammasome activation in human gingival epithelial cells

Hong Li, Xiaoli Zhou, Jianli Zhang
Pages: 1039-1044
Published online on: 25 July 2014

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Article

Achyranthes bidentata polysaccharides activate the Wnt/β-catenin signaling pathway to promote chondrocyte proliferation

Xiaping Weng, Pingdong Lin, Fayuan Liu, Jiashou Chen, Huiting Li, Lichan Huang, Chunsong Zhen, Huifeng Xu, Xianxiang Liu, Hongzhi Ye, Xihai Li
Pages: 1045-1050
Published online on: 29 July 2014

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Article

FPDHP, a novel anticancer agent, induces cell detachment and caspase-dependent apoptosis in Caki cells

Jun Soo Park, Wan Tae Kim, Shin Kim, Taeg Kyu Kwon, Byeong-Churl Jang, Eung-Seok Lee, Jong Wook Park
Pages: 1051-1056
Published online on: 04 August 2014

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Article

Angiotensin-(1-7) attenuates damage to podocytes induced by preeclamptic serum through MAPK pathways

Jimei Tian, Lihong Zhang, Yunjiao Zhou, Jing Xiao, Sheran Li, Yaping Chen, Zhongdong Qiao, Jianying Niu, Yong Gu
Pages: 1057-1064
Published online on: 29 July 2014

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Article

Profile of microRNAs associated with aging in rat liver

Shima Mimura, Hisakazu Iwama, Kiyohito Kato, Kei Nomura, Mitsuyoshi Kobayashi, Hirohito Yoneyama, Hisaaki Miyoshi, Joji Tani, Asahiro Morishita, Takashi Himoto, Akihiro Deguchi, Takako Nomura, Teppei Sakamoto, Koji Fujita, Emiko Maeda, Kunihiko Izuishi, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 1065-1072
Published online on: 11 August 2014

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Article

Silibinin protects β cells from glucotoxicity through regulation of the Insig-1/SREBP-1c pathway

Ke Chen, Liling Zhao, Honghui He, Xinxing Wan, Fang Wang, Zhaohui Mo
Pages: 1073-1080
Published online on: 08 August 2014

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Article

Downregulation of Notch1 inhibits the invasion of human hepatocellular carcinoma HepG2 and MHCC97H cells through the regulation of PTEN and FAK

Yan-Jian Hu, Hong-Ying Li, Kai-Jie Qiu, Da-Chuan Li, Jia-Hui Zhou, Yan-Hua Hu, Feng-Min Zhang
Pages: 1081-1086
Published online on: 08 August 2014

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Article

The anti-atherogenic effects of berberine on foam cell formation are mediated through the upregulation of sirtuin 1

Liyi Chi, Lijing Peng, Na Pan, Xiaojing Hu, Yanhai Zhang
Pages: 1087-1093
Published online on: 28 July 2014

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Article

AP-2α downregulation by cigarette smoke condensate is counteracted by p53 in human lung cancer cells

Xiangjun Meng, Cuida Meng, Bing Yang, Li Zhao, Xuefei Sun, Yun Su, Hongyang Liu, Feiyue Fan, Xiaodong Liu, Lili Jia
Pages: 1094-1100
Published online on: 17 July 2014

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Article

Anti-inflammatory potential of peat moss extracts in lipopolysaccharide-stimulated RAW 264.7 macrophages

Woo-Suk Choi, Jin-Woo Jeong, Sung Ok Kim, Gi-Young Kim, Byung-Woo Kim, Cheol Min Kim, Yong-Bae Seo, Woe-Yeon Kim, Sang-Yeol Lee, Kwon-Ho Jo, Young Ju Choi, Yung Hyun Choi, Gun-Do Kim
Pages: 1101-1109
Published online on: 06 August 2014

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Article

Suppression of the TGF-β/Smad signaling pathway and inhibition of hepatic stellate cell proliferation play a role in the hepatoprotective effects of curcumin against alcohol-induced hepatic fibrosis

Nanzheng Chen, Qianqian Geng, Jianbao Zheng, Sai He, Xiongwei Huo, Xuejun Sun
Pages: 1110-1116
Published online on: 25 July 2014

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Article

Activation of G-protein-coupled receptor 40 attenuates the cisplatin-induced apoptosis of human renal proximal tubule epithelial cells

Seong Kwon Ma, Soo Yeon Joo, Hoon-In Choi, Eun Hui Bae, Kwang Il Nam, Jongun Lee, Soo Wan Kim
Pages: 1117-1123
Published online on: 01 August 2014

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Article

Modulation of gene expression in endothelial cells in response to high LET nickel ion irradiation

Michaël Beck, Charlotte Rombouts, Marjan Moreels, An Aerts, Roel Quintens, Kevin Tabury, Arlette Michaux, Ann Janssen, Mieke Neefs, Eric Ernst, Birger Dieriks, Ryonfa Lee, Winnok H. De Vos, Charles Lambert, Patrick Van Oostveldt, Sarah Baatout
Pages: 1124-1132
Published online on: 11 August 2014

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Article

Upregulation of HIF-1α protein induces mitochondrial autophagy in primary cortical cell cultures through the inhibition of the mTOR pathway

Gu Gong, Ling Hu, Yinghai Liu, Shurong Bai, Xuemei Dai, Liang Yin, Yangyang Sun, Xiaowu Wang, Lichao Hou
Pages: 1133-1140
Published online on: 14 July 2014

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Article

Alternatively spliced variants of the regucalcin gene in various human normal and tumor tissues

Tomiyasu Murata, Masayoshi Yamaguchi
Pages: 1141-1146
Published online on: 18 July 2014

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Article

siRNA-mediated silencing of Wnt5a regulates inflammatory responses in atherosclerosis through the MAPK/NF-κB pathways

Lei Yang, Yingjie Chu, Yuhang Wang, Xiangmei Zhao, Wenke Xu, Peirong Zhang, Xiaoyu Liu, Shujuan Dong, Wenqi He, Chuanyu Gao
Pages: 1147-1152
Published online on: 22 July 2014

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Article

Sphingosine-1-phosphate inhibits the adipogenic differentiation of 3T3-L1 preadipocytes

Myung-Hee Moon, Jae-Kyo Jeong, You-Jin Lee, Jae-Won Seol, Sang-Youel Park
Pages: 1153-1158
Published online on: 16 July 2014

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Article

Sirt3 attenuates hydrogen peroxide-induced oxidative stress through the preservation of mitochondrial function in HT22 cells

Shu-Hui Dai, Tao Chen, Yu-Hai Wang, Jie Zhu, Peng Luo, Wei Rao, Yue-Fan Yang, Zhou Fei, Xiao-Fan Jiang
Pages: 1159-1168
Published online on: 04 August 2014

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Article

FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression

Asako Ishitsuka, Etsuko Fujine, Yoko Mizutani, Chisato Tawada, Hiroyuki Kanoh, Yoshiko Banno, Mariko Seishima
Pages: 1169-1174
Published online on: 06 August 2014

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Article

Sodium selenite inhibits leukemia HL-60 cell proliferation and induces cell apoptosis by enhancing the phosphorylation of JNK1 and increasing the expression of p21 and p27

Sun Wu, Yonghua Bao, Dong Ma, Youmei Zi, Cui Yang, Man Yang, Mengtao Xing, Wancai Yang
Pages: 1175-1179
Published online on: 15 July 2014

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Article

Purification and biochemical characterization of a fibrin(ogen)olytic metalloprotease from Macrovipera mauritanica snake venom which induces vascular permeability

Eun Hee Lee, Jung Eun Park, Jong Woo Park, Jung Sup Lee
Pages: 1180-1190
Published online on: 24 July 2014

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Article Open Access

Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Review Open Access

Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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Review Open Access

High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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