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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2014 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

MicroRNAs regulate vascular smooth muscle cell functions in atherosclerosis (Review)

Xin Yu, Zheng Li
Pages: 923-933
Published online on: 15 July 2014

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Review

Atherosclerosis and tumor suppressor molecules (Review)

Miho Suzuki, Akari Minami, Atsuko Nakanishi, Keiko Kobayashi, Satoru Matsuda, Yasunori Ogura, Yasuko Kitagishi
Pages: 934-940
Published online on: 25 July 2014

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Article Open Access

Cold atmospheric plasma treatment selectively targets head and neck squamous cell carcinoma cells

Rafael Guerrero-Preston, Takenori Ogawa, Mamoru Uemura, Gary Shumulinsky, Blanca L. Valle, Francesca Pirini, Rajani Ravi, David Sidransky, Michael Keidar, Barry Trink
Pages: 941-946
Published online on: 11 July 2014

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Article Open Access

Plasma proteomic changes during hypothermic and normothermic cardiopulmonary bypass in aortic surgeries

Teiji Oda, Akane Yamaguchi, Masao Yokoyama, Koji Shimizu, Kosaku Toyota, Tetsuro Nikai, Ken‑Ichi Matsumoto
Pages: 947-956
Published online on: 15 July 2014

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Article Open Access

Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis

Zhigang Cheng, Ling Li, Xueying Mo, Lu Zhang, Yongqiu Xie, Qulian Guo, Yunjiao Wang
Pages: 957-966
Published online on: 31 July 2014

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Article Open Access

Stomach antral endocrine cells in patients with irritable bowel syndrome

Magdy El-Salhy, Odd Helge Gilja, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 967-974
Published online on: 08 August 2014

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Article Open Access

Identification and association of the single nucleotide polymorphisms, C-509T, C+466T and T+869C, of the TGF-β1 gene in patients with asthma and their influence on the mRNA expression level of TGF-β1

Michał Panek, Tadeusz Pietras, Artur Fabijan, Jan Zioło, Łukasz Wieteska, Beata Małachowska, Wojciech Fendler, Janusz Szemraj, Piotr Kuna
Pages: 975-986
Published online on: 11 August 2014

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Article Open Access

Bone mesenchymal stem cell transplantation via four routes for the treatment of acute liver failure in rats

Lihua Sun, Xiaotang Fan, Lijuan Zhang, Guixiu Shi, Maimaiti Aili, Xiaobo Lu, Tao Jiang, Yuexin Zhang
Pages: 987-996
Published online on: 11 August 2014

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Article Open Access

Isolation, culture and phenotypic characterization of human sweat gland epithelial cells

Yunhe Gao, Meiying Li, Xueyan Zhang, Tingting Bai, Guanfan Chi, Jin Yu Liu, Yulin Li
Pages: 997-1003
Published online on: 14 July 2014

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Article Open Access

Proliferation and odontogenic differentiation of BMP2 gene‑transfected stem cells from human tooth apical papilla: An in vitro study

Wen Zhang, Xiaolei Zhang, Junqi Ling, Wei Liu, Xinchun  Zhang, Jinglei Ma, Jianmao Zheng
Pages: 1004-1012
Published online on: 24 July 2014

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Article Open Access

Curcumin inhibits human retinal pigment epithelial cell proliferation

Yun Sun, Zhi-Peng You
Pages: 1013-1019
Published online on: 23 July 2014

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Article

Inhibition by caffeic acid of the influenza A virus multiplication in vitro

Hirotoshi Utsunomiya, Masao Ichinose, Keiko Ikeda, Misao Uozaki, Junko Morishita, Tomomi Kuwahara, A. Hajime Koyama, Hisashi Yamasaki
Pages: 1020-1024
Published online on: 22 July 2014

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Article

Quercetin protects against high glucose-induced damage in bone marrow-derived endothelial progenitor cells

Li-Rong Zhao, Yu-Jun Du, Lei Chen, Zhi-Gang Liu, Yue-Hai Pan, Jian-Feng Liu, Bin Liu
Pages: 1025-1031
Published online on: 14 July 2014

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Article

Dexmedetomidine suppresses interleukin-1β-induced interleukin-6 synthesis in rat glial cells

Kumiko Tanabe, Rie Matsushima-Nishiwaki, Osamu Kozawa, Hiroki Iida
Pages: 1032-1038
Published online on: 24 July 2014

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Article

Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced inflammasome activation in human gingival epithelial cells

Hong Li, Xiaoli Zhou, Jianli Zhang
Pages: 1039-1044
Published online on: 25 July 2014

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Article

Achyranthes bidentata polysaccharides activate the Wnt/β-catenin signaling pathway to promote chondrocyte proliferation

Xiaping Weng, Pingdong Lin, Fayuan Liu, Jiashou Chen, Huiting Li, Lichan Huang, Chunsong Zhen, Huifeng Xu, Xianxiang Liu, Hongzhi Ye, Xihai Li
Pages: 1045-1050
Published online on: 29 July 2014

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Article

FPDHP, a novel anticancer agent, induces cell detachment and caspase-dependent apoptosis in Caki cells

Jun Soo Park, Wan Tae Kim, Shin Kim, Taeg Kyu Kwon, Byeong-Churl Jang, Eung-Seok Lee, Jong Wook Park
Pages: 1051-1056
Published online on: 04 August 2014

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Article

Angiotensin-(1-7) attenuates damage to podocytes induced by preeclamptic serum through MAPK pathways

Jimei Tian, Lihong Zhang, Yunjiao Zhou, Jing Xiao, Sheran Li, Yaping Chen, Zhongdong Qiao, Jianying Niu, Yong Gu
Pages: 1057-1064
Published online on: 29 July 2014

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Article

Profile of microRNAs associated with aging in rat liver

Shima Mimura, Hisakazu Iwama, Kiyohito Kato, Kei Nomura, Mitsuyoshi Kobayashi, Hirohito Yoneyama, Hisaaki Miyoshi, Joji Tani, Asahiro Morishita, Takashi Himoto, Akihiro Deguchi, Takako Nomura, Teppei Sakamoto, Koji Fujita, Emiko Maeda, Kunihiko Izuishi, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 1065-1072
Published online on: 11 August 2014

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Article

Silibinin protects β cells from glucotoxicity through regulation of the Insig-1/SREBP-1c pathway

Ke Chen, Liling Zhao, Honghui He, Xinxing Wan, Fang Wang, Zhaohui Mo
Pages: 1073-1080
Published online on: 08 August 2014

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Article

Downregulation of Notch1 inhibits the invasion of human hepatocellular carcinoma HepG2 and MHCC97H cells through the regulation of PTEN and FAK

Yan-Jian Hu, Hong-Ying Li, Kai-Jie Qiu, Da-Chuan Li, Jia-Hui Zhou, Yan-Hua Hu, Feng-Min Zhang
Pages: 1081-1086
Published online on: 08 August 2014

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Article

The anti-atherogenic effects of berberine on foam cell formation are mediated through the upregulation of sirtuin 1

Liyi Chi, Lijing Peng, Na Pan, Xiaojing Hu, Yanhai Zhang
Pages: 1087-1093
Published online on: 28 July 2014

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Article

AP-2α downregulation by cigarette smoke condensate is counteracted by p53 in human lung cancer cells

Xiangjun Meng, Cuida Meng, Bing Yang, Li Zhao, Xuefei Sun, Yun Su, Hongyang Liu, Feiyue Fan, Xiaodong Liu, Lili Jia
Pages: 1094-1100
Published online on: 17 July 2014

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Article

Anti-inflammatory potential of peat moss extracts in lipopolysaccharide-stimulated RAW 264.7 macrophages

Woo-Suk Choi, Jin-Woo Jeong, Sung Ok Kim, Gi-Young Kim, Byung-Woo Kim, Cheol Min Kim, Yong-Bae Seo, Woe-Yeon Kim, Sang-Yeol Lee, Kwon-Ho Jo, Young Ju Choi, Yung Hyun Choi, Gun-Do Kim
Pages: 1101-1109
Published online on: 06 August 2014

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Article

Suppression of the TGF-β/Smad signaling pathway and inhibition of hepatic stellate cell proliferation play a role in the hepatoprotective effects of curcumin against alcohol-induced hepatic fibrosis

Nanzheng Chen, Qianqian Geng, Jianbao Zheng, Sai He, Xiongwei Huo, Xuejun Sun
Pages: 1110-1116
Published online on: 25 July 2014

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Article

Activation of G-protein-coupled receptor 40 attenuates the cisplatin-induced apoptosis of human renal proximal tubule epithelial cells

Seong Kwon Ma, Soo Yeon Joo, Hoon-In Choi, Eun Hui Bae, Kwang Il Nam, Jongun Lee, Soo Wan Kim
Pages: 1117-1123
Published online on: 01 August 2014

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Article

Modulation of gene expression in endothelial cells in response to high LET nickel ion irradiation

Michaël Beck, Charlotte Rombouts, Marjan Moreels, An Aerts, Roel Quintens, Kevin Tabury, Arlette Michaux, Ann Janssen, Mieke Neefs, Eric Ernst, Birger Dieriks, Ryonfa Lee, Winnok H. De Vos, Charles Lambert, Patrick Van Oostveldt, Sarah Baatout
Pages: 1124-1132
Published online on: 11 August 2014

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Article

Upregulation of HIF-1α protein induces mitochondrial autophagy in primary cortical cell cultures through the inhibition of the mTOR pathway

Gu Gong, Ling Hu, Yinghai Liu, Shurong Bai, Xuemei Dai, Liang Yin, Yangyang Sun, Xiaowu Wang, Lichao Hou
Pages: 1133-1140
Published online on: 14 July 2014

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Article

Alternatively spliced variants of the regucalcin gene in various human normal and tumor tissues

Tomiyasu Murata, Masayoshi Yamaguchi
Pages: 1141-1146
Published online on: 18 July 2014

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Article

siRNA-mediated silencing of Wnt5a regulates inflammatory responses in atherosclerosis through the MAPK/NF-κB pathways

Lei Yang, Yingjie Chu, Yuhang Wang, Xiangmei Zhao, Wenke Xu, Peirong Zhang, Xiaoyu Liu, Shujuan Dong, Wenqi He, Chuanyu Gao
Pages: 1147-1152
Published online on: 22 July 2014

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Article

Sphingosine-1-phosphate inhibits the adipogenic differentiation of 3T3-L1 preadipocytes

Myung-Hee Moon, Jae-Kyo Jeong, You-Jin Lee, Jae-Won Seol, Sang-Youel Park
Pages: 1153-1158
Published online on: 16 July 2014

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Article

Sirt3 attenuates hydrogen peroxide-induced oxidative stress through the preservation of mitochondrial function in HT22 cells

Shu-Hui Dai, Tao Chen, Yu-Hai Wang, Jie Zhu, Peng Luo, Wei Rao, Yue-Fan Yang, Zhou Fei, Xiao-Fan Jiang
Pages: 1159-1168
Published online on: 04 August 2014

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Article

FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression

Asako Ishitsuka, Etsuko Fujine, Yoko Mizutani, Chisato Tawada, Hiroyuki Kanoh, Yoshiko Banno, Mariko Seishima
Pages: 1169-1174
Published online on: 06 August 2014

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Article

Sodium selenite inhibits leukemia HL-60 cell proliferation and induces cell apoptosis by enhancing the phosphorylation of JNK1 and increasing the expression of p21 and p27

Sun Wu, Yonghua Bao, Dong Ma, Youmei Zi, Cui Yang, Man Yang, Mengtao Xing, Wancai Yang
Pages: 1175-1179
Published online on: 15 July 2014

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Article

Purification and biochemical characterization of a fibrin(ogen)olytic metalloprotease from Macrovipera mauritanica snake venom which induces vascular permeability

Eun Hee Lee, Jung Eun Park, Jong Woo Park, Jung Sup Lee
Pages: 1180-1190
Published online on: 24 July 2014

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Journal Cover
July-2026 Volume 58 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Sex differences in cardiovascular‑kidney‑metabolic syndrome: From pathogenesis to treatment response (Review)

Yanqin Fan, Hongtu Hu, Jing Cheng
Article Number: 202
Published online on: 27 May 2026

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Retraction Open Access

[Retracted] BAMBI inhibits inflammation through the activation of autophagy in experimental spinal cord injury

Yin Yang, Chunyang Guo, Bo Liao, Junjun Cao, Chen Liang, Xijing He
Article Number: 201
Published online on: 25 May 2026

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Article Open Access

Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 200
Published online on: 22 May 2026

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Article Open Access

Ginsenoside Rg3 potentiates cisplatin antitumor activity while mitigating nephrotoxicity through SIRT1‑mediated suppression of the NLRP3 inflammasome

Jinghui Zhai, Yueming Zhang, Jiawei Gong, Li Fu, Sixi Zhang
Article Number: 199
Published online on: 22 May 2026

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Article Open Access

Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning

Qiming Xu, Chunjing Xu, Ziyang Liu, Jianrao Lu, Jing Hu, Lin Liao
Article Number: 198
Published online on: 21 May 2026

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Article Open Access

CTRP3 alleviates neuropathic pain by improving mitochondrial biogenesis and mitochondrial unfolded protein response via spinal SIRT1 in rats

Tianzhu Liu, Longqing Zhang, Wei Mei
Article Number: 197
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Article Number: 196
Published online on: 20 May 2026

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Article Open Access

Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice

Xin Jin, Xuan Liu, Yun-Juan Wang, Zi-Li Lei, Yan-Hong Yang
Article Number: 195
Published online on: 20 May 2026

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Article Open Access

Endothelial NOX4‑driven oxidative stress inhibition reverses HtrA1 deficiency‑induced blood‑brain barrier disruption and cognitive impairment

Shi-Na Song, Jun-Ying Wu, Mao-Mei Song, Xiao-Feng Li, Jian-Ming Wang, Wen-Hui Jia, Chang-Xin Li, Sui-Yi Xu
Article Number: 194
Published online on: 19 May 2026

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Review Open Access

Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review)

Sen Chen, Xiaofei Cui
Article Number: 193
Published online on: 19 May 2026

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Review Open Access

Unraveling the molecular landscape of chronic radiation injury: From oxidative stress signaling to translational modeling (Review)

Zhenjun Xi, Xiaodong Li, Chunhui Yang, Li Wang, Jingxin Mao, Qianqian Liu, Chang Liu, Qian Li, Yuanfang Hou, Jie Wan, Chengzhuo Yang, Feiji Sun, Chao Yu, Miao Wang, Baocheng Yuan, Yongsheng Liu, Qing Hu, Li Zhang, Xuemei Li, Xiaobing Li
Article Number: 192
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Cocktail therapy with a combination of interferon, ribavirin and angiotensin‑II type 1 receptor blocker attenuates murine liver fibrosis development

Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Kosuke Kaji, Yosuke Aihara, Yusaku Shirai, Junichi Yoshii, Koji Yanase, Hiroshi Fukui
Article Number: 191
Published online on: 18 May 2026

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Review Open Access

Autophagy and metabolic homeostasis: Exploration in obesity‑related metabolic diseases (Review)

Chenglin Lu, Xiangyu Qi, Yuting Tong, Peng Lu, Dandan Luo, Qingbo Guan, Chunxiao Yu
Article Number: 190
Published online on: 14 May 2026

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Review Open Access

Primary cilia dysfunction: A critical driver of metabolic diseases (Review)

Xiaojing Wang, Yi Jin, Kejia Xie, Pengfei Yao, Liguo Song, Hongdan Liu, Yanjie Tan
Article Number: 189
Published online on: 14 May 2026

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Review Open Access

Gut‑brain axis in anesthesia and critical illness: Molecular crosstalk and its impact on delirium and outcome (Review)

Xigang Ma, Yongsen Zhao
Article Number: 188
Published online on: 14 May 2026

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Article Open Access

Betulinic acid alleviates the inflammatory injury of osteoblasts in osteoporosis by augmenting autophagy via the AMPK-mTOR signaling pathway

Yiwei Zhao, Zechao Qu, Lin Liu, Yong Zhang, Xiaohao Wang, Bo Zhang, Yining Gong, Liang Yan
Article Number: 187
Published online on: 13 May 2026

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Correction Open Access

[Corrigendum] Induction of cardiomyocyte‑like cells from hair follicle cells in mice

Yong-Hee Kim, Bang-Jin Kim, Seok-Man Kim, Sun-Uk Kim, Buom-Yong Ryu
Article Number: 186
Published online on: 13 May 2026

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Review Open Access

Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review)

Guiqing Chen, Hongyan Jia, Kai Zhao, Chang Gao, Yue Liu, Hong Zhu, Dakai Yang, Yun Cai
Article Number: 185
Published online on: 13 May 2026

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Article Open Access

Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms

Hui Fang, Min Shu, Jiaju Wang, Heng Tian, Jianguo Zhang, Ying Hu, He Li, Huan Zhou, Kangsheng Gu, Zhenhua Ren
Article Number: 184
Published online on: 12 May 2026

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Review Open Access

Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review)

Chengyi Ming, Ni Zhu, You Yu, Hong Zhou, Meichun Hu
Article Number: 183
Published online on: 12 May 2026

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Review Open Access

Rab27: Molecular switch of tumor exosome secretion (Review)

Mengtian Tang, Zhongjian Zhu, Huaxin Duan, Shiming Tan, Mengzhou Shen, Xianjie Jiang, Qiu Peng, Linda Oyang, Zongyao Ren, Yujuan Zhou, Qianjin Liao
Article Number: 182
Published online on: 12 May 2026

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Article Open Access

IL‑17A+ γδT cell activation via the HMGB1‑TLR2/4‑NF‑κB signaling pathways in biliary atresia

Meng-Xin Zhang, Jing-Feng Tang, Mei Hong, Ying Yang, Yun Zhou, Shui-Qing Chi, Li-Ying Rong, Guo-Qing Cao, Xi Zhang, Jin-Xiang Zhang, Shao-Tao Tang
Article Number: 181
Published online on: 11 May 2026

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Article Open Access

CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis

Lumeng Song, Ping Xiong, Amu Jike, Xiaochao Xia, Lifang Mao, Zihao Wang, Yinchuan Cheng, Shumin Wang, Shizheng Tan, Dongnan Yu, Zheng Li, Xiaoping Tang, Shun Li
Article Number: 180
Published online on: 11 May 2026

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Correction Open Access

[Corrigendum] Expression of FKBP52 in the ovaries of PCOS rats

Shiyan Song, Yong Tan
Article Number: 179
Published online on: 11 May 2026

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Article Open Access

miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis

Xiaoyu Wang, Lin Song, Jiafeng Wang, Qianqian Xie, Yan Wang, Chunyan Li, Tianqi Wang, Yifeng Du
Article Number: 178
Published online on: 08 May 2026

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Review Open Access

Radiotherapy and cytokines: A systems view of immunotherapy and toxicity (Review)

Siyuan Zhou, Yurong Jiang, Jixu Fan, Minjie Guo, Yi Wen, Chunhua Dai
Article Number: 177
Published online on: 08 May 2026

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Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)

Xiwei Wang, Shuang Li, Xiaotian Ge, Tao Xie, Sainan Li, Ruiqi Yuan, Tianxi Li, Hui Yuan
Article Number: 176
Published online on: 06 May 2026

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Expression of Concern Open Access

[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai
Article Number: 175
Published online on: 06 May 2026

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Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)

Ziang Geng, Shu Guan, Shaoqi Du, Shuo Zhang, Jiaxin Hao, Siyuan Tian, Chen Zhu, Shaonan Du
Article Number: 174
Published online on: 06 May 2026

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Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review)

Wenhui Gu, Haifeng Zhang, Lisha Ye, Fangming Liu, Ting Xu, Yinxian Yu, Guohua Wang
Article Number: 173
Published online on: 05 May 2026

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Retraction Open Access

[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Article Number: 172
Published online on: 04 May 2026

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Article Open Access

Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Article Open Access

Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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August-2026 Volume 58 Issue 2

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Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review)

Yaping Wu, Hao Yu, Ling Xia, Li Yang, Yu Zhou, Qian Yu
Article Number: 216
Published online on: 08 June 2026

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Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)

Boying Zhu, Chaoyang Wang, Peng Liu, Zhifeng Qu, Ran Qi, Shengjiang Chen, Huanzhang Niu
Article Number: 215
Published online on: 08 June 2026

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Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress

Miao Xue, Junshuai Feng, Xiaorong Mao
Article Number: 214
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Article Number: 213
Published online on: 08 June 2026

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Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

Wei Dai, Jiabin Wu, Xiaotong Ma, Mingyu Wu, Ke Li, Haoyang Gao, Wenhong Wang, Weihua Xiao
Article Number: 212
Published online on: 05 June 2026

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Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)

Zheming Yang, Jiayin Li, Lingxiao Zhao, Dali Zhang, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 211
Published online on: 04 June 2026

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Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

Stefanny M. Figueroa, Siyi Huang, Javier Reyes‑Osorio, Jean-Jacques Boffa, Cristián A. Amador, Christos E. Chadjichristos, Louis Boutin
Article Number: 210
Published online on: 04 June 2026

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

Zhanli Yang, Chuntao Yang, Liangcan Xiao, Xinxue Liao, Aiping Lan, Xiuyu Wang, Ruixian Guo, Peixi Chen, Chengheng Hu, Jianqiang Feng
Article Number: 209
Published online on: 03 June 2026

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Article Open Access

Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
Article Number: 208
Published online on: 03 June 2026

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Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

Zhibo Fan, Qiyue Fu, Tao Sun, Yutong Zhong, Yuefan Ma, Jingwei Jian, Shuosheng Yuan, Shenghong Li, Xiaomei Xu
Article Number: 207
Published online on: 02 June 2026

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Retraction Open Access

[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

Xiaoxu Gao, Yan Cai, Ruifang An
Article Number: 206
Published online on: 02 June 2026

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Review

Multi‑scale experimental models for the study of angiogenesis (Review)

Qin Yu, Jiarui Hu, Shuangshuang Yuan, Jiexia Gan, Mao Luo, Jianbo Wu, Liqun Wang
Article Number: 205
Published online on: 28 May 2026

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Review Open Access

Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

Lianting Chen, Feiqiong Gao, Qianru Mei, Yujie Li, Qun Cai, Xudong Feng
Article Number: 204
Published online on: 28 May 2026

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Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
Article Number: 203
Published online on: 28 May 2026

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