|
1
|
Kaneto H and Matsuoka TA: Involvement of
oxidative stress in suppression of insulin biosynthesis under
diabetic conditions. Int J Mol Sci. 13:13680–13690. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Pérez S, Pereda J, Sabater L and Sastre J:
Redox signaling in acute pancreatitis. Redox Biol. 5:1–14. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Keane KN, Cruzat VF, Carlessi R, de
Bittencourt PI Jr and Newsholme P: Molecular events linking
oxidative stress and inflammation to insulin resistance and β-cell
dysfunction. Oxid Med Cell Longev 2015. 181643:2015. View Article : Google Scholar
|
|
4
|
Mishra V: Oxidative stress and role of
antioxidant supplementation in critical illness. Clin Lab.
53:199–209. 2007.PubMed/NCBI
|
|
5
|
Manna P and Jain SK: Obesity, oxidative
stress, adipose tissue dysfunction, and the associated health
risks: causes and therapeutic strategies. Metab Syndr Relat Disord.
13:423–444. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Yadav UC, Rani V, Deep G, Singh RK and
Palle K: Oxidative stress in metabolic disorders: pathogenesis,
prevention, and therapeutics. Oxid Med Cell Longev 2016.
9137629:2016. View Article : Google Scholar :
|
|
7
|
Xie MX, Long M, Liu Y, Qin C and Wang YD:
Characterization of the interaction between human serum albumin and
morin. Biochim Biophys Acta. 1760:1184–1191. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Dhanasekar C and Rasool M: Morin, a
dietary bioflavonol suppresses monosodium urate crystal-induced
inflammation in an animal model of acute gouty arthritis with
reference to NLRP3 inflammasome, hypo-xanthine phosphoribosyl
transferase, and inflammatory mediators. Eur J Pharmacol.
786:116–127. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Prahalathan P, Kumar S and Raja B: Morin
attenuates blood pressure and oxidative stress in
deoxycorticosterone acetate-salt hypertensive rats: a biochemical
and histopathological evaluation. Metabolism. 61:1087–1099. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Abuohashish HM, Al-Rejaie SS, Al-Hosaini
KA, Parmar MY and Ahmed MM: Alleviating effects of morin against
experimentally-induced diabetic osteopenia. Diabetol Metab Syndr.
5:52013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kok LD, Wong YP, Wu TW, Chan HC, Kwok TT
and Fung KP: Morin hydrate: a potential antioxidant in minimizing
the free-radicals-mediated damage to cardiovascular cells by
anti-tumor drugs. Life Sci. 67:91–99. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Singh MP, Jakhar R and Kang SC: Morin
hydrate attenuates the acrylamide-induced imbalance in antioxidant
enzymes in a murine model. Int J Mol Med. 36:992–1000. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Dilshara MG, Jayasooriya RG, Lee S, Choi
YH and Kim GY: Morin downregulates nitric oxide and prostaglandin
E2 production in LPS-stimulated BV2 microglial cells by
suppressing NF-κB activity and activating HO-1 induction. Environ
Toxicol Pharmacol. 44:62–68. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Vanitha P, Uma C, Suganya N,
Bhakkiyalakshmi E, Suriyanarayanan S, Gunasekaran P,
Sivasubramanian S and Ramkumar KM: Modulatory effects of morin on
hyperglycemia by attenuating the hepatic key enzymes of
carbohydrate metabolism and β-cell function in
streptozotocin-induced diabetic rats. Environ Toxicol Pharmacol.
37:326–335. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Zhang R, Kang KA, Piao MJ, Maeng YH, Lee
KH, Chang WY, You HJ, Kim JS, Kang SS and Hyun JW: Cellular
protection of morin against the oxidative stress induced by
hydrogen peroxide. Chem Biol Interact. 177:21–27. 2009. View Article : Google Scholar
|
|
16
|
Zheng A, Li H, Xu J, Cao K, Li H, Pu W,
Yang Z, Peng Y, Long J, Liu J, et al: Activation of the AMPK-FOXO3
pathway reduces fatty acid-induced increase in intracellular
reactive oxygen species by upregulating thioredoxin. Diabetes.
58:2246–2257. 2009. View Article : Google Scholar
|
|
17
|
Zheng A, Li H, Xu J, Cao K, Li H, Pu W,
Yang Z, Peng Y, Long J, Liu J, et al: Hydroxytyrosol improves
mitochondrial function and reduces oxidative stress in the brain of
db/db mice: role of AMP-activated protein kinase activation. Br J
Nutr. 113:1667–1676. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Guan Y, Cui ZJ, Sun B, Han LP, Li CJ and
Chen LM: Celastrol attenuates oxidative stress in the skeletal
muscle of diabetic rats by regulating the AMPK-PGC1α-SIRT3
signaling pathway. Int J Mol Med. 37:1229–1238. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ceolotto G, Gallo A, Papparella I, Franco
L, Murphy E, Iori E, Pagnin E, Fadini GP, Albiero M, Semplicini A,
et al: Rosiglitazone reduces glucose-induced oxidative stress
mediated by NAD(P)H oxidase via AMPK-dependent mechanism.
Arterioscler Thromb Vasc Biol. 27:2627–2633. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Essick EE and Sam F: Oxidative stress and
autophagy in cardiac disease, neurological disorders, aging and
cancer. Oxid Med Cell Longev. 3:168–177. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Sid B, Verrax J and Calderon PB: Role of
AMPK activation in oxidative cell damage: implications for
alcohol-induced liver disease. Biochem Pharmacol. 86:200–209. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Maiese K, Chong ZZ and Shang YC:
OutFOXOing disease and disability: the therapeutic potential of
targeting FoxO proteins. Trends Mol Med. 14:219–227. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Nho RS and Hergert P: FoxO3a and disease
progression. World J Biol Chem. 5:346–354. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kato M, Yuan H, Xu ZG, Lanting L, Li SL,
Wang M, Hu MC, Reddy MA and Natarajan R: Role of the Akt/FoxO3a
pathway in TGF-beta1-mediated mesangial cell dysfunction: a novel
mechanism related to diabetic kidney disease. J Am Soc Nephrol.
17:3325–3335. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Sundaresan NR, Gupta M, Kim G, Rajamohan
SB, Isbatan A and Gupta MP: Sirt3 blocks the cardiac hypertrophic
response by augmenting Foxo3a-dependent antioxidant defense
mechanisms in mice. J Clin Invest. 119:2758–2771. 2009.PubMed/NCBI
|
|
26
|
Turdi S, Li Q, Lopez FL and Ren J:
Catalase alleviates cardiomyocyte dysfunction in diabetes: role of
Akt, forkhead transcriptional factor and silent information
regulator 2. Life Sci. 81:895–905. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Colombo SL and Moncada S: AMPKalpha1
regulates the antioxidant status of vascular endothelial cells.
Biochem J. 421:163–169. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zrelli H, Matsuoka M, Kitazaki S, Zarrouk
M and Miyazaki H: Hydroxytyrosol reduces intracellular reactive
oxygen species levels in vascular endothelial cells by upregulating
catalase expression through the AMPK-FOXO3a pathway. Eur J
Pharmacol. 660:275–282. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Carmichael J, DeGraff WG, Gazdar AF, Minna
JD and Mitchell JB: Evaluation of a tetrazolium-based semiautomated
colorimetric assay: assessment of chemosensitivity testing. Cancer
Res. 47:936–942. 1987.PubMed/NCBI
|
|
30
|
Nicoletti I, Migliorati G, Pagliacci MC,
Grignani F and Riccardi C: A rapid and simple method for measuring
thymocyte apoptosis by propidium iodide staining and flow
cytometry. J Immunol Methods. 139:271–279. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
32
|
Chandak PG, Gaikwad AB and Tikoo K:
Gallotannin ameliorates the development of streptozotocin-induced
diabetic nephropathy by preventing the activation of PARP.
Phytother Res. 23:72–77. 2009. View Article : Google Scholar
|
|
33
|
Guzyk MM, Tykhomyrov AA, Nedzvetsky VS,
Prischepa IV, Grinenko TV, Yanitska LV and Kuchmerovska TM:
Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors reduce reactive
gliosis and improve angiostatin levels in retina of diabetic rats.
Neurochem Res. 41:2526–2537. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Chen F, Xiong H, Wang J, Ding X, Shu G and
Mei Z: Antidiabetic effect of total flavonoids from Sanguis
draxonis in type 2 diabetic rats. J Ethnopharmacol. 149:729–736.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Lenzen S: Oxidative stress: the vulnerable
beta-cell. Biochem Soc Trans. 36:343–347. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Kim AD, Kang KA, Piao MJ, Kim KC, Zheng J,
Yao CW, Cha JW, Hyun CL, Kang HK, Lee NH, et al: Cytoprotective
effect of eckol against oxidative stress-induced mitochondrial
dysfunction: involvement of the FoxO3a/AMPK pathway. J Cell
Biochem. 115:1403–1411. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Szkudelski T: The mechanism of alloxan and
streptozotocin action in B cells of the rat pancreas. Physiol Res.
50:537–546. 2001.
|
|
38
|
Lei H, Han J, Wang Q, Guo S, Sun H and
Zhang X: Effects of sesamin on streptozotocin (STZ)-induced NIT-1
pancreatic β-cell damage. Int J Mol Sci. 13:16961–16970. 2012.
View Article : Google Scholar
|
|
39
|
Zhang R, Kim JS, Kang KA, Piao MJ, Kim KC
and Hyun JW: Protective mechanism of KIOM-4 in
streptozotocin-induced pancreatic β-cells damage is involved in the
inhibition of endoplasmic reticulum stress. Evid Based Complement
Alternat Med. 2011:1–10. 2011. View Article : Google Scholar
|
|
40
|
Bansal P, Paul P, Mudgal J, Nayak PG,
Pannakal ST, Priyadarsini KI and Unnikrishnan MK: Antidiabetic,
antihyperlipidemic and antioxidant effects of the flavonoid rich
fraction of Pilea microphylla (L.) in high fat
diet/streptozotocin-induced diabetes in mice. Exp Toxicol Pathol.
64:651–658. 2012. View Article : Google Scholar
|
|
41
|
Sendrayaperumal V, Iyyam Pillai S and
Subramanian S: Design, synthesis and characterization of
zinc-morin, a metal flavonol complex and evaluation of its
antidiabetic potential in HFD-STZ induced type 2 diabetes in rats.
Chem Biol Interact. 219:9–17. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Lortz S, Tiedge M, Nachtwey T, Karlsen AE,
Nerup J and Lenzen S: Protection of insulin-producing RINm5F cells
against cytokine-mediated toxicity through overexpression of
antioxidant enzymes. Diabetes. 49:1123–1130. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Benhamou PY, Moriscot C, Richard MJ,
Beatrix O, Badet L, Pattou F, Kerr-Conte J, Chroboczek J,
Lemarchand P and Halimi S: Adenovirus-mediated catalase gene
transfer reduces oxidant stress in human, porcine and rat
pancreatic islets. Diabetologia. 41:1093–1100. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Xu B, Moritz JT and Epstein PN:
Overexpression of catalase provides partial protection to
transgenic mouse beta cells. Free Radic Biol Med. 27:830–837. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ola MS, Aleisa AM, Al-Rejaie SS,
Abuohashish HM, Parmar MY, Alhomida AS and Ahmed MM: Flavonoid,
morin inhibits oxidative stress, inflammation and enhances
neurotrophic support in the brain of streptozotocin-induced
diabetic rats. Neurol Sci. 35:1003–1008. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Greer EL, Oskoui PR, Banko MR, Maniar JM,
Gygi MP, Gygi SP and Brunet A: The energy sensor AMP-activated
protein kinase directly regulates the mammalian FOXO3 transcription
factor. J Biol Chem. 282:30107–30119. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Tothova Z, Kollipara R, Huntly BJ, Lee BH,
Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams
IR, Sears C, et al: FoxOs are critical mediators of hematopoietic
stem cell resistance to physiologic oxidative stress. Cell.
128:325–339. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Huang W, Li G, Qiu J, Gonzalez P and
Challa P: Protective effects of resveratrol in experimental retinal
detachment. PLoS One. 8:e757352013. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Alcendor RR, Gao S, Zhai P, Zablocki D,
Holle E, Yu X, Tian B, Wagner T, Vatner SF and Sadoshima J: Sirt1
regulates aging and resistance to oxidative stress in the heart.
Circ Res. 100:1512–1521. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Bhakkiyalakshmi E, Shalini D, Sekar TV,
Rajaguru P, Paulmurugan R and Ramkumar KM: Therapeutic potential of
pterostilbene against pancreatic beta-cell apoptosis mediated
through Nrf2. Br J Pharmacol. 171:1747–1757. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Liu MH, Yuan C, He J, Tan TP, Wu SJ, Fu
HY, Liu J, Yu S, Chen YD, Le QF, et al: Resveratrol protects PC12
cells from high glucose-induced neurotoxicity via PI3K/Akt/FoxO3a
pathway. Cell Mol Neurobiol. 35:513–522. 2015. View Article : Google Scholar
|
|
52
|
Kukidome D, Nishikawa T, Sonoda K, Imoto
K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Matsumura T and
Araki E: Activation of AMP-activated protein kinase reduces
hyperglycemia-induced mitochondrial reactive oxygen species
production and promotes mitochondrial biogenesis in human umbilical
vein endothelial cells. Diabetes. 55:120–127. 2006. View Article : Google Scholar
|
