Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Molecular Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1107-3756 Online ISSN: 1791-244X
presentation
International Journal of Molecular Medicine

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

  • Selected Issue
  • Current Issue
  • Forthcoming Issue
  • Special Issues
    • Open Special Issues
    • About Special Issues
  • Trending Articles
    • Most Read
    • Most Cited (Dimensions)
      • Past Two Years
      • Total
    • Most Cited (Crossref)
      • Past Year
      • Total
    • Social Media
      • Past Month
      • Past Year
      • Total
  • Information
    • Information for Authors
    • Contact
    • Editorial Policies
    • Editorial Academy
    • Aims and Scope
    • Abstracting and Indexing
    • Bibliographic Information
  • Archive
Journal Cover
March-2018 Volume 41 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Paediatric Virology and its interaction between basic science and clinical practice (Review)

Ioannis N. Mammas, Anne Greenough, Maria Theodoridou, Anna Kramvis, Maria Rusan, Angeliki Melidou, Paraskevi Korovessi, Georgia Papaioannou, Alexia Papatheodoropoulou, Chryssie Koutsaftiki, Maria Liston, George Sourvinos, Demetrios A. Spandidos
Pages: 1165-1176
Published online on: 04 January 2018

  • View Full Article Download
Review Open Access

Genetically‑modified stem cells in treatment of human diseases: Tissue kallikrein (KLK1)‑based targeted therapy (Review)

Marina Devetzi, Maria Goulielmaki, Nicolas Khoury, Demetrios A. Spandidos, Georgia Sotiropoulou, Ioannis Christodoulou, Vassilis Zoumpourlis
Pages: 1177-1186
Published online on: 03 January 2018

  • View Full Article Download
Review Open Access

Molecular regulation of epithelial-to-mesenchymal transition in tumorigenesis (Review)

Henrieta Škovierová, Terézia Okajčeková, Ján Strnádel, Eva Vidomanová, Erika Halašová
Pages: 1187-1200
Published online on: 13 December 2017

  • View Full Article Download
Review Open Access

Mutual regulation of the Hippo/Wnt/LPA/TGF‑β signaling pathways and their roles in glaucoma (Review)

Xin Wang, Guoli Huai, Hailian Wang, Yuande Liu, Ping Qi, Wei Shi, Jie Peng, Hongji Yang, Shaoping Deng, Yi Wang
Pages: 1201-1212
Published online on: 29 December 2017

  • View Full Article Download
Review

Structural and functional failure of fibrillin‑1 in human diseases (Review)

Sandra Schrenk, Carola Cenzi, Thomas Bertalot, Maria Teresa Conconi, Rosa Di Liddo
Pages: 1213-1223
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

Tumor necrosis factor-α acts reciprocally with solute carrier family 26, member 3, (downregulated-in-adenoma) and reduces its expression, leading to intestinal inflammation

Xiangming Ding, Dongxiao Li, Mengke Li, Dean Tian, Hongbing Yu, Qin Yu
Pages: 1224-1232
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

Logistic regression analysis for the identification of the metastasis-associated signaling pathways of osteosarcoma

Yang Liu, Wei Sun, Xiaojun Ma, Yuedong Hao, Gang Liu, Xiaohui Hu, Houlai Shang, Pengfei Wu, Zexue Zhao, Weidong Liu
Pages: 1233-1244
Published online on: 02 January 2018

  • View Full Article Download
Article Open Access

Extracellular polysaccharides purified from Aureobasidium pullulans SM‑2001 (Polycan) inhibit dexamethasone‑induced muscle atrophy in mice

Jong‑Min Lim, Young Joon Lee, Hyung‑Rae Cho, Dong‑Chan Park, Go‑Woon Jung, Sae Kwang Ku, Jae‑Suk Choi
Pages: 1245-1264
Published online on: 10 November 2017

  • View Full Article Download
Article Open Access

KDM3A inhibition attenuates high concentration insulin‑induced vascular smooth muscle cell injury by suppressing MAPK/NF‑κB pathways

Bo‑Fang Zhang, Hong Jiang, Jing Chen, Xin Guo, Qi Hu, Shuo Yang
Pages: 1265-1274
Published online on: 29 December 2017

  • View Full Article Download
Article Open Access

Effect of long non-coding RNA PVT1 on cell proliferation and migration in melanoma

Lamei Chen, Dongmei Ma, Yuanyuan Li, Xiaoying Li, Lei Zhao, Jing Zhang, Yali Song
Pages: 1275-1282
Published online on: 20 December 2017

  • View Full Article Download
Article Open Access

Protective effect of angiotensin-(1-7) against hyperglycaemia-induced injury in H9c2 cardiomyoblast cells via the PI3K̸Akt signaling pathway Corrigendum in /10.3892/ijmm.2017.3322

Yi-Ying Yang, Xiu-Ting Sun, Zheng-Xun Li, Wei-Yan Chen, Xiang Wang, Mei-Ling Liang, Hui Shi, Zhi-Sheng Yang, Wu-Tao Zeng
Pages: 1283-1292
Published online on: 15 December 2017

  • View Full Article Download
Article Open Access

Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway

Lijun Zhang, Changgeng Xu, Wei Hu, Pin Wu, Cong Qin, Jie Zhang
Pages: 1293-1304
Published online on: 18 December 2017

  • View Full Article Download
Article Open Access

Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-κB signaling pathway

Yunpeng Luan, Yanmei Li, Lina Zhu, Shuangqing Zheng, Dechang Mao, Zhuxue Chen, Yong Cao
Pages: 1305-1314
Published online on: 21 December 2017

  • View Full Article Download
Article Open Access

Arkadia protein expression is reduced in the liver during the progression of hepatic fibrosis

Fei Hou, Ruixia Liu, Xiaoya Liu, Lijian Cui, Xiaozheng Yu, Yan Wen, Huiguo Ding, Chenghong Yin
Pages: 1315-1322
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

Direct binding of Toll-like receptor 4 to ionotropic glutamate receptor N-methyl-D-aspartate subunit 1 induced by lipopolysaccharide in microglial cells N9 and EOC 20

Jie Cui, Siyuan Yu, Yihui Li, Pan Li, Feng Liu
Pages: 1323-1330
Published online on: 19 December 2017

  • View Full Article Download
Article Open Access

NPPB modulates apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling

Lixia Sun, Yaru Dong, Jing Zhao, Yuan Yin, Bainan Tong, Yajuan Zheng, Hua Xin
Pages: 1331-1338
Published online on: 15 December 2017

  • View Full Article Download
Article Open Access

Effects of ERK1/2 S-nitrosylation on ERK1/2 phosphorylation and cell survival in glioma cells

Lei Jin, Yujia Cao, Tong Zhang, Peng Wang, Daofei Ji, Xuejiao Liu, Hengliang Shi, Lei Hua, Rutong Yu, Shangfeng Gao
Pages: 1339-1348
Published online on: 20 December 2017

  • View Full Article Download
Article Open Access

Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis

Xiao Lv, Danbo Wang, Yue Ma, Zaiqiu Long
Pages: 1349-1356
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

Estrogen receptor‑β‑dependent effects of saikosaponin‑d on the suppression of oxidative stress‑induced rat hepatic stellate cell activation

Renye Que, Yanting Shen, Jianlin Ren, Zhihui Tao, Xiaoyan Zhu, Yong Li
Pages: 1357-1364
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

Metformin-induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

Biao Hao, Yan Xiao, Fang Song, Xiangshu Long, Jing Huang, Maobo Tian, Shiyan Deng, Qiang Wu
Pages: 1365-1376
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

A 16-gene expression signature to distinguish stage I from stage II lung squamous carcinoma

Rui Wang, Yuxing Cai, Baoping Zhang, Zhengxia Wu
Pages: 1377-1384
Published online on: 19 December 2017

  • View Full Article Download
Article Open Access

3D-cultured adipose tissue-derived stem cells inhibit liver cancer cell migration and invasion through suppressing epithelial-mesenchymal transition

Haihua Xie, Naishun Liao, Fenghua Lan, Zhixiong Cai, Xiaolong Liu, Jingfeng Liu
Pages: 1385-1396
Published online on: 20 December 2017

  • View Full Article Download
Article Open Access

shRNA-induced silencing of Ras-related C3 botulinum toxin substrate 1 inhibits the proliferation of colon cancer cells through upregulation of BAD and downregulation of cyclin D1

You‑Sheng Huang, Na Jie, Yi‑Xin Zhang, Ke‑Jian Zou, Yang Weng
Pages: 1397-1408
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

Amelioration of streptozotocin‑induced pancreatic β cell damage by morin: Involvement of the AMPK‑FOXO3‑catalase signaling pathway

Ning Wang, Jiahui Zhang, Mengting Qin, Wenjing Yi, Shuang Yu, Yi Chen, Jing Guan, Rui Zhang
Pages: 1409-1418
Published online on: 29 December 2017

  • View Full Article Download
Article Open Access

Support vector machine classifier for prediction of the metastasis of colorectal cancer

Jiajun Zhi, Jiwei Sun, Zhongchuan Wang, Wenjun Ding
Pages: 1419-1426
Published online on: 02 January 2018

  • View Full Article Download
Article Open Access

A murine model of dry eye induced by topical administration of erlotinib eye drops

Qi‑Chen Yang, Jing Bao, Cheng Li, Gang Tan, An‑Hua Wu, Lei Ye, Lin‑Hong Ye, Qiong Zhou, Yi Shao
Pages: 1427-1436
Published online on: 29 December 2017

  • View Full Article Download
Article Open Access

Genistein attenuates di‑(2‑ethylhexyl) phthalate-induced testicular injuries via activation of Nrf2/HO‑1 following prepubertal exposure

Liandong Zhang, Hecheng Li, Ming Gao, Tongdian Zhang, Zhizhong Wu, Ziming Wang, Tie Chong
Pages: 1437-1446
Published online on: 09 January 2018

  • View Full Article Download
Article Open Access

Synergistic antitumor effect of brusatol combined with cisplatin on colorectal cancer cells

Hai‑Ming Chen, Zheng‑Quan Lai, Hui‑Jun Liao, Jian‑Hui Xie, Yan‑Fang Xian, Yun‑Long Chen, Siu‑Po Ip, Zhi‑Xiu Lin, Zi‑Ren Su
Pages: 1447-1454
Published online on: 09 January 2018

  • View Full Article Download
Article Open Access

GW4064 attenuates lipopolysaccharide‑induced hepatic inflammation and apoptosis through inhibition of the Toll‑like receptor 4‑mediated p38 mitogen‑activated protein kinase signaling pathway in mice

Hsuan‑Miao Liu, Tzung‑Yan Lee, Jyh‑Fei Liao
Pages: 1455-1462
Published online on: 08 January 2018

  • View Full Article Download
Article Open Access

Chemical conversion of human lung fibroblasts into neuronal cells

Xiao‑Yu Wan, Li‑Yun Xu, Bing Li, Qiu‑Hong Sun, Qiu‑Liang Ji, Dong‑Dong Huang, Lan Zhao, Yong‑Tao Xiao
Pages: 1463-1468
Published online on: 10 January 2018

  • View Full Article Download
Article Open Access

The role of IL‑16 gene polymorphisms in endometriosis

Michail Matalliotakis, Maria I. Zervou, Elias Eliopoulos, Charoula Matalliotaki, Nilufer Rahmioglu, Ioannis Kalogiannidis, Krina Zondervan, Demetrios A. Spandidos, Ioannis Matalliotakis, George N. Goulielmos
Pages: 1469-1476
Published online on: 09 January 2018

  • View Full Article Download
Article Open Access

Exogenous hydrogen sulfide protects human umbilical vein endothelial cells against high glucose‑induced injury by inhibiting the necroptosis pathway

Jiaqiong Lin, Meiji Chen, Donghong Liu, Ruixian Guo, Kai Lin, Haiou Deng, Ximei Zhi, Weijie Zhang, Jianqiang Feng, Wen Wu
Pages: 1477-1486
Published online on: 19 December 2017

  • View Full Article Download
Article Open Access

Ginsenoside Rg3 inhibits keloid fibroblast proliferation, angiogenesis and collagen synthesis in vitro via the TGF‑β/Smad and ERK signaling pathways

Mengyao Tang, Weiwei Bian, Liying Cheng, Lu Zhang, Rong Jin, Wenbo Wang, Yuguang Zhang
Pages: 1487-1499
Published online on: 04 January 2018

  • View Full Article Download
Article Open Access

Genome expression profiling predicts the molecular mechanism of peripheral myelination

Xiaoming Wu
Pages: 1500-1508
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

Changes in microRNA expression in the brachial plexus avulsion model of neuropathic pain

Yuzhou Liu, Le Wang, Jie Lao, Xin Zhao
Pages: 1509-1517
Published online on: 19 December 2017

  • View Full Article Download
Article Open Access

CCN1/Cyr61 enhances the function of hepatic stellate cells in promoting the progression of hepatocellular carcinoma

Zhi‑Qiang Li, Wei‑Ru Wu, Chen Zhao, Xiao‑Li Zhang, Zhong Yang, Jing Pan, Wei‑Ke Si
Pages: 1518-1528
Published online on: 29 December 2017

  • View Full Article Download
Article Open Access

miR-152 is involved in the proliferation and metastasis of ovarian cancer through repression of ERBB3

Lian-Wei Li, Hong-Qi Xiao, Rong Ma, Meng Yang, Wan Li, Ge Lou
Pages: 1529-1535
Published online on: 15 December 2017

  • View Full Article Download
Article Open Access

MALAT1 enhanced the proliferation of human osteoblasts treated with ultra‑high molecular weight polyethylene by targeting VEGF via miR‑22‑5p

Xucheng Yang, Yingying Zhang, Yusheng Li, Ting Wen
Pages: 1536-1546
Published online on: 04 January 2018

  • View Full Article Download
Article Open Access

Maternal chromium restriction induces insulin resistance in adult mice offspring through miRNA

Qian Zhang, Xiaofang Sun, Xinhua Xiao, Jia Zheng, Ming Li, Miao Yu, Fan Ping, Zhixin Wang, Cuijuan Qi, Tong Wang, Xiaojing Wang
Pages: 1547-1559
Published online on: 18 December 2017

  • View Full Article Download
Article Open Access

Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway

Zhongze Liu, Liangzi Li, Weigang Chen, Qimeng Wang, Weidong Xiao, Yuanhang Ma, Baifa Sheng, Xiang Li, Lihua Sun, Min Yu, Hua Yang
Pages: 1560-1572
Published online on: 22 December 2017

  • View Full Article Download
Article Open Access

Pin1 facilitates isoproterenol‑induced cardiac fibrosis and collagen deposition by promoting oxidative stress and activating the MEK1/2‑ERK1/2 signal transduction pathway in rats

Xian Wu, Mingjiang Li, Su‑Qin Chen, Sha Li, Furong Guo
Pages: 1573-1583
Published online on: 29 December 2017

  • View Full Article Download
Article Open Access

Differential microRNA expression profiles and bioinformatics analysis between young and aging spontaneously hypertensive rats

Jingfeng Wang, Jingjing Zhang, Xuefeng Ding, Yanyan Wang, Zhiming  Li, Weipeng Zhao, Jianguo Jia, Jingmin Zhou, Junbo Ge
Pages: 1584-1594
Published online on: 09 January 2018

  • View Full Article Download
Article Open Access

miR‑203‑3p participates in the suppression of diabetes‑associated osteogenesis in the jaw bone through targeting Smad1

Yuying Tang, Leilei Zheng, Jie Zhou, Yang Chen, Lan Yang, Feng Deng, Yun Hu
Pages: 1595-1607
Published online on: 09 January 2018

  • View Full Article Download
Article Open Access

Anthocyanins inhibit high glucose-induced renal tubular cell apoptosis caused by oxidative stress in db/db mice

Jinying Wei, Haijiang Wu, Haiqiang Zhang, Fang Li, Shurui Chen, Baohua Hou, Yonghong Shi, Lijuan Zhao, Huijun Duan
Pages: 1608-1618
Published online on: 10 January 2018

  • View Full Article Download
Article

miR-200c regulates the proliferation, apoptosis and invasion of gastric carcinoma cells through the downregulation of EDNRA expression

Wei Wei, Li Shi, Weichang Chen, Liyu Hu, Dan Chen, Xiaoying Shi, Hua Xiang, Cunguo Guo, Zhenping Wu
Pages: 1619-1626
Published online on: 12 December 2017

  • View Full Article Download
Article

Evodiamine promotes differentiation and inhibits proliferation of C2C12 muscle cells

Xiangping Yao, Taiyong Yu, Chen Zhao, Youlei Li, Ying Peng, Fengxue Xi, Gongshe Yang
Pages: 1627-1634
Published online on: 13 December 2017

  • View Full Article Download
Article

Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment

Qing‑Chun Li, Qing‑Feng Li, Yan‑Lin Wang, Hong‑Liang Sun, Zheng‑Yao Jiang
Pages: 1635-1642
Published online on: 05 January 2018

  • View Full Article Download
Article

2,3,5,4'‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside inhibits septic serum‑induced inflammatory injury via interfering with the ROS‑MAPK‑NF‑κB signaling pathway in pulmonary aortic endothelial cells

Wenqiang Li, Ruifang Sun, Sumei Zhou, Jinluan Ma, Yingguang Xie, Bingcan Xu, Huibao Long, Keqin Luo, Kuaifa Fang
Pages: 1643-1650
Published online on: 19 December 2017

  • View Full Article Download
Article

High-mobility group protein B1 silencing promotes susceptibility of retinoblastoma cells to chemotherapeutic drugs through downregulating nuclear factor-κB

Yong Chai, Juhua Xiao, Shouhua Zhang, Yunyan Du, Zhipeng Luo, Xin Zhou, Kai Huang
Pages: 1651-1658
Published online on: 10 January 2018

  • View Full Article Download
Article

BCSG1 siRNA delivered by lentiviral vector suppressed proliferation and migration of MDA-MB-231 cells

Jin-Song He, Ni Xie, Jian-Bo Yang, Hong Guan, Wei-Cai Chen, Chang Zou, Yi-Wen Ouyang, You-Sheng Mao, Xue-Ying Luo, Yue Pan, Li Fu
Pages: 1659-1664
Published online on: 29 December 2017

  • View Full Article Download
Article

MicroRNA-107 prevents amyloid-β-induced neurotoxicity and memory impairment in mice

Bohui Shu, Xiaoyan Zhang, Ganqin Du, Qizhi Fu, Lina Huang
Pages: 1665-1672
Published online on: 22 December 2017

  • View Full Article Download
Article

Identification and characterization of epitopes from influenza A virus hemagglutinin that induce broadly cross-reactive antibodies

Yuan Li, Hanyu Hu, Zongli Qi, Jingying Sun, Yan Li, Qing Feng, Chunyan Guo, Haifang Wang, Penghua Zhao, Yang Liu, Xiangrong Zhao, Guanghua Wang, Hai Zhang, Libin Liu, Jun Hu
Pages: 1673-1682
Published online on: 22 December 2017

  • View Full Article Download
Article

Petasites japonicus bakkenolide B inhibits lipopolysaccharide‑induced pro‑inflammatory cytokines via AMPK/Nrf2 induction in microglia

Sun Young Park, Min Hyun Choi, Geuntae Park, Young‑Whan Choi
Pages: 1683-1692
Published online on: 28 December 2017

  • View Full Article Download
Article

Cardioprotection by exenatide: A novel mechanism via improving mitochondrial function involving the GLP-1 receptor/cAMP/PKA pathway

Guanglei Chang, Jian Liu, Shu Qin, Youqin Jiang, Peng Zhang, Hui Yu, Kai Lu, Nan Zhang, Li Cao, Ying Wang, Yong Li, Dongying Zhang
Pages: 1693-1703
Published online on: 12 December 2017

  • View Full Article Download
Article

Sphingosine-1-phosphate ameliorates the cardiac hypertrophic response through inhibiting the activity of histone deacetylase-2

Hui Yan, Shaowei Yi, Hang Zhuang, Lujin Wu, Dao Wen Wang, Jiangang Jiang
Pages: 1704-1714
Published online on: 15 December 2017

  • View Full Article Download
Article

Proteasome inhibition protects against diet-induced gallstone formation through modulation of cholesterol and bile acid homeostasis

Eun‑Ji Lee, Min Hee Kim, Ye‑Ryung Kim, Joo‑Won Park, Woo‑Jae Park
Pages: 1715-1723
Published online on: 15 December 2017

  • View Full Article Download
Article

Activation of transient receptor potential vanilloid 1 protects the heart against apoptosis in ischemia/reperfusion injury through upregulating the PI3K/Akt signaling pathway

Xiao‑Xue Jiang, Guan‑Yu Liu, Han Lei, Zuo‑Ling Li, Qing‑Ping Feng, Wei Huang
Pages: 1724-1730
Published online on: 21 December 2017

  • View Full Article Download
Article

Placenta‑associated serum exosomal miR‑155 derived from patients with preeclampsia inhibits eNOS expression in human umbilical vein endothelial cells

Li Shen, Yujing Li, Ruotian Li, Zhenyu Diao, Muyi Yany, Mengfei Wu, Haixiang Sun, Guijun Yan, Yali Hu
Pages: 1731-1739
Published online on: 08 January 2018

  • View Full Article Download
Article

MicroRNA-493-5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Pages: 1740-1748
Published online on: 02 January 2018

  • View Full Article Download
Article

Effects of thymosin β4 on oxygen‑glucose deprivation and reoxygenation‑induced injury

Hua Ji, Linhao Xu, Zheng Wang, Xinli Fan, Lihui Wu
Pages: 1749-1755
Published online on: 09 January 2018

  • View Full Article Download
Article

Cynandione A inhibits lipopolysaccharide-induced cell adhesion via suppression of the protein expression of VCAM‑1 in human endothelial cells

Keun Hyung Park, Jiyoung Kim, Eunjoo H. Lee, Tae Hoon Lee
Pages: 1756-1764
Published online on: 10 January 2018

  • View Full Article Download
Article

miR‑214 reduces cisplatin resistance by targeting netrin‑1 in bladder cancer cells

Jiao Liu, Jianbin Bi, Zeliang Li, Zhenhua Li, Xiankui Liu, Chuize Kong
Pages: 1765-1773
Published online on: 10 January 2018

  • View Full Article Download
Article

MicroRNA-137 regulates hypoxia-induced retinal ganglion cell apoptosis through Notch1

Haiyan Li, Zhongqiao Zhu, Jianrong Liu, Jianzhou Wang, Chaoyi Qu
Pages: 1774-1782
Published online on: 12 December 2017

  • View Full Article Download
Article

Methanol extract of Guettarda speciosa Linn. inhibits the production of inflammatory mediators through the inactivation of Syk and JNK in macrophages Corrigendum in /10.3892/ijmm.2019.4079

Hien Thi Thu Le, Young‑Chang Cho, Sayeon Cho
Pages: 1783-1791
Published online on: 10 January 2018

  • View Full Article Download
Journal Cover
January-2026 Volume 57 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

  • View Full Article Download
Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

  • View Full Article Download
Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

  • View Full Article Download
Article Open Access

Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

  • View Full Article Download
Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

  • View Full Article Download
Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

  • Purchase Full Text Article Purchase Download
Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

  • View Full Article Download
Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

  • View Full Article Download
Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

  • View Full Article Download
Review Open Access

Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

  • View Full Article Download
Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

  • View Full Article Download
Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

  • View Full Article Download
Review Open Access

High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

  • View Full Article Download
Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

  • View Full Article Download
Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

  • View Full Article Download
Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

  • View Full Article Download
Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

  • Purchase Full Text Article Purchase Download
Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

  • View Full Article Download
Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

  • View Full Article Download
Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

  • View Full Article Download
Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

  • View Full Article Download
Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

  • View Full Article Download
Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

  • Purchase Full Text Article Purchase Download
Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

  • View Full Article Download
Journal Cover
February-2026 Volume 57 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

  • Download
Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

  • Download
Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

  • Download
Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

  • Download
Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

  • Download
Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

  • Download
Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

  • Download
Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

  • Purchase Download
Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

  • Download
Select a topic from the Information tab...
Special issues coming soon...
No data
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team