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Article

Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment

  • Authors:
    • Qing‑Chun Li
    • Qing‑Feng Li
    • Yan‑Lin Wang
    • Hong‑Liang Sun
    • Zheng‑Yao Jiang
  • View Affiliations / Copyright

    Affiliations: Department of Reproductive Medicine, The Affiliated Hospital of Binzhou Medical University, Binzhou, Shandong 256603, P.R. China, Smart Division Gas, Qingdao iESLab Electronic Co., Ltd., Qingdao 266071, P.R. China, Department of Physiology, Qingdao University Medical College, Qingdao, Shandong 266071, P.R. China
  • Pages: 1635-1642
    |
    Published online on: January 5, 2018
       https://doi.org/10.3892/ijmm.2018.3365
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Abstract

The aim of the present study was to determine whether arcuate nucleus (ARC) lesions affect the ghrelin level in the plasma and the stomach in monosodium glutamate (MSG)‑treated mice. The aim of the present study was to investigate whether the ARC was destroyed in mice treated neonatally with MSG, and whether the ARC lesions affect the ghrelin level in the plasma and lipid mobilization in MSG‑treated mice. The results revealed that MSG led to a marked reduction in ARC cresyl violet staining, tyrosine hydroxylase-immunoreactive (IR) neurons and neuropeptide Y‑IR fibers, compared with saline controls. MSG‑treated mice exhibited significantly increased body mass compared with saline controls, and MSG treatment did not prevent food deprivation‑induced decrease in white adipose tissue mass compared with controls. Plasma ghrelin levels were significantly increased in MSG‑treated mice that were fasted for 48 h, compared with the levels prior to fasting and re‑feeding, and the preprandial peak of plasma ghrelin persisted in MSG‑treated mice. In summary, the ARC was not found to be essential for food deprivation‑induced lipid mobilization and preprandial peak in MSG‑treated mice. However, this finding does not mean that ARC neurons do not contribute to food sensing and lipid mobilization under normal conditions, as compensatory mechanisms may have emerged after the ablation of ARC neurons.
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View References

1 

Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H and Kangawa K: Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 402:656–660. 1999. View Article : Google Scholar : PubMed/NCBI

2 

Date Y, Kojima M, Hosoda H, Sawaguchi A, Mondal MS, Suganuma T, Matsukura S, Kangawa K and Nakazato M: Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology. 141:4255–4261. 2000. View Article : Google Scholar : PubMed/NCBI

3 

Mizutani M, Atsuchi K, Asakawa A, Matsuda N, Fujimura M, Inui A, Kato I and Fujimiya M: Localization of acyl ghrelin- and des-acyl ghrelin-immunoreactive cells in the rat stomach and their responses to intragastric pH. Am J Physiol Gastrointest Liver Physiol. 297:G974–G980. 2009. View Article : Google Scholar

4 

Tschöp M, Weyer C, Tataranni PA, Devanarayan V, Ravussin E and Heiman ML: Circulating ghrelin levels are decreased in human obesity. Diabetes. 50:707–709. 2001. View Article : Google Scholar : PubMed/NCBI

5 

Jeon TY, Lee S, Kim HH, Kim YJ, Son HC, Kim DH and Sim MS: Changes in plasma ghrelin concentration immediately after gastrectomy in patients with early gastric cancer. J Clin Endocrinol Metab. 89:5392–5396. 2004. View Article : Google Scholar : PubMed/NCBI

6 

Lu S, Guan JL, Wang QP, Uehara K, Yamada S, Goto N, Date Y, Nakazato M, Kojima M, Kangawa K, et al: Immunocytochemical observation of ghrelin-containing neurons in the rat arcuate nucleus. Neurosci Lett. 321:157–160. 2002. View Article : Google Scholar : PubMed/NCBI

7 

Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, et al: The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron. 37:649–661. 2003. View Article : Google Scholar : PubMed/NCBI

8 

Schwartz MW, Woods SC, Porte D Jr, Seeley RJ and Baskin DG: Central nervous system control of food intake. Nature. 404:661–671. 2000. View Article : Google Scholar : PubMed/NCBI

9 

Abizaid A and Horvath TL: Brain circuits regulating energy homeostasis. Regul Pept. 149:3–10. 2008. View Article : Google Scholar : PubMed/NCBI

10 

Wang L, Saint-Pierre DH and Taché Y: Peripheral ghrelin selectively increases Fos expression in neuropeptide Y-synthesizing neurons in mouse hypothalamic arcuate nucleus. Neurosci Lett. 325:47–51. 2002. View Article : Google Scholar : PubMed/NCBI

11 

Kamegai J, Tamura H, Shimizu T, Ishii S, Sugihara H and Wakabayashi I: Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats. Diabetes. 50:2438–2443. 2001. View Article : Google Scholar : PubMed/NCBI

12 

Tschöp M, Flora DB, Mayer JP and Heiman ML: Hypophysectomy prevents ghrelin-induced adiposity and increases gastric ghrelin secretion in rats. Obes Res. 10:991–999. 2002. View Article : Google Scholar : PubMed/NCBI

13 

Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE and Weigle DS: A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes. 50:1714–1719. 2001. View Article : Google Scholar : PubMed/NCBI

14 

Tschöp M, Wawarta R, Riepl RL, Friedrich S, Bidlingmaier M, Landgraf R and Folwaczny C: Post-prandial decrease of circulating human ghrelin levels. J Endocrinol Invest. 24:RC19–RC21. 2001. View Article : Google Scholar : PubMed/NCBI

15 

Williams DL and Cummings DE: Regulation of ghrelin in physiologic and pathophysiologic states. J Nutr. 135:1320–1325. 2005. View Article : Google Scholar : PubMed/NCBI

16 

Olney JW: Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science. 164:719–721. 1969. View Article : Google Scholar : PubMed/NCBI

17 

Perez VJ and Olney JW: Accumulation of glutamic acid in the arcuate nucleus of the hypothalamus of the infant mouse followng subcutaneous administration of monosodium glutamate. J Neurochem. 19:1777–1782. 1972. View Article : Google Scholar : PubMed/NCBI

18 

Takasaki Y: Studies on brain lesion by administration of monosodium L-glutamate to mice. I. Brain lesions in infant mice caused by administration of monosodium L-glutamate. Toxicology. 9:293–305. 1978. View Article : Google Scholar : PubMed/NCBI

19 

Nikoletseas MM: Obesity in exercising, hypophagic rats treated with monosodium glutamate. Physiol Behav. 19:767–773. 1977. View Article : Google Scholar : PubMed/NCBI

20 

Small CJ, Liu YL, Stanley SA, Connoley IP, Kennedy A, Stock MJ and Bloom SR: Chronic CNS administration of Agouti-related protein (Agrp) reduces energy expenditure. Int J Obes Relat Metab Disord. 27:530–533. 2003. View Article : Google Scholar : PubMed/NCBI

21 

Yasuda T, Masaki T, Kakuma T and Yoshimatsu H: Centrally administered ghrelin suppresses sympathetic nerve activity in brown adipose tissue of rats. Neurosci Lett. 349:75–78. 2003. View Article : Google Scholar : PubMed/NCBI

22 

Mercer JG, Moar KM, Ross AW, Hoggard N and Morgan PJ: Photoperiod regulates arcuate nucleus POMC, AGRP, and leptin receptor mRNA in Siberian hamster hypothalamus. Am J Physiol Regul Integr Comp Physiol. 278:R271–R281. 2000. View Article : Google Scholar : PubMed/NCBI

23 

Ebihara K, Ogawa Y, Katsuura G, Numata Y, Masuzaki H, Satoh N, Tamaki M, Yoshioka T, Hayase M, Matsuoka N, et al: Involvement of agouti-related protein, an endogenous antagonist of hypothalamic melanocortin receptor, in leptin action. Diabetes. 48:2028–2033. 1999. View Article : Google Scholar : PubMed/NCBI

24 

Kristensen P, Judge ME, Thim L, Ribel U, Christjansen KN, Wulff BS, Clausen JT, Jensen PB, Madsen OD, Vrang N, et al: Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature. 393:72–76. 1998. View Article : Google Scholar : PubMed/NCBI

25 

Bunyan J, Murrell EA and Shah PP: The induction of obesity in rodents by means of monosodium glutamate. Br J Nutr. 35:25–39. 1976. View Article : Google Scholar : PubMed/NCBI

26 

Bamshad M, Aoki VT, Adkison MG, Warren WS and Bartness TJ: Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue. Am J Physiol. 275:R291–R299. 1998.PubMed/NCBI

27 

Bowers RR, Festuccia WTL, Song CK, Shi H, Migliorini RH and Bartness TJ: Sympathetic innervation of white adipose tissue and its regulation of fat cell number. Am J Physiol Regul Integr Comp Physiol. 286:R1167–R1175. 2004. View Article : Google Scholar : PubMed/NCBI

28 

Shi H and Bartness TJ: Neurochemical phenotype of sympathetic nervous system outflow from brain to white fat. Brain Res Bull. 54:375–385. 2001. View Article : Google Scholar : PubMed/NCBI

29 

Song CK and Bartness TJ: CNS sympathetic outflow neurons to white fat that express MEL receptors may mediate seasonal adiposity. Am J Physiol Regul Integr Comp Physiol. 281:R666–R672. 2001. View Article : Google Scholar : PubMed/NCBI

30 

Druce MR, Wren AM, Park AJ, Milton JE, Patterson M, Frost G, Ghatei MA, Small C and Bloom SR: Ghrelin increases food intake in obese as well as lean subjects. Int J Obes. 29:1130–1136. 2005. View Article : Google Scholar

31 

Wren AM, Small CJ, Ward HL, Murphy KG, Dakin CL, Taheri S, Kennedy AR, Roberts GH, Morgan DG, Ghatei MA, et al: The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology. 141:4325–4328. 2000. View Article : Google Scholar : PubMed/NCBI

32 

Davies JS, Kotokorpi P, Eccles SR, Barnes SK, Tokarczuk PF, Allen SK, Whitworth HS, Guschina IA, Evans BA, Mode A, et al: Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Mol Endocrinol. 23:914–924. 2009. View Article : Google Scholar : PubMed/NCBI

33 

Tschöp M, Smiley DL and Heiman ML: Ghrelin induces adiposity in rodents. Nature. 407:908–913. 2000. View Article : Google Scholar : PubMed/NCBI

34 

Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP and Purnell JQ: Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med. 346:1623–1630. 2002. View Article : Google Scholar : PubMed/NCBI

35 

Stengel A, Goebel M, Wang L and Taché Y: Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: Role as regulators of food intake and body weight. Peptides. 31:357–369. 2010. View Article : Google Scholar

36 

Guan JL, Wang QP, Kageyama H, Takenoya F, Kita T, Matsuoka T, Funahashi H and Shioda S: Synaptic interactions between ghrelin- and neuropeptide Y-containing neurons in the rat arcuate nucleus. Peptides. 24:1921–1928. 2003. View Article : Google Scholar

37 

Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE and Weigle DS: A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes. 50:1714–1719. 2001. View Article : Google Scholar : PubMed/NCBI

38 

Luquet S, Perez FA, Hnasko TS and Palmiter RD: NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science. 310:683–685. 2005. View Article : Google Scholar : PubMed/NCBI

39 

Luquet S, Phillips CT and Palmiter RD: NPY/AgRP neurons are not essential for feeding responses to glucoprivation. Peptides. 28:214–225. 2007. View Article : Google Scholar

40 

Tamura H, Kamegai J, Shimizu T, Ishii S, Sugihara H and Oikawa S: Ghrelin stimulates GH but not food intake in arcuate nucleus ablated rats. Endocrinology. 143:3268–3275. 2002. View Article : Google Scholar : PubMed/NCBI

41 

Faulconbridge LF, Grill HJ, Kaplan JM and Daniels D: Caudal brainstem delivery of ghrelin induces fos expression in the nucleus of the solitary tract, but not in the arcuate or paraventricular nuclei of the hypothalamus. Brain Res. 1218:151–157. 2008. View Article : Google Scholar : PubMed/NCBI

42 

Chen HY, Trumbauer ME, Chen AS, Weingarth DT, Adams JR, Frazier EG, Shen Z, Marsh DJ, Feighner SD, Guan XM, et al: Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein. Endocrinology. 145:2607–2612. 2004. View Article : Google Scholar : PubMed/NCBI

43 

Ariyasu H, Takaya K, Tagami T, Ogawa Y, Hosoda K, Akamizu T, Suda M, Koh T, Natsui K, Toyooka S, et al: Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab. 86:4753–4758. 2001. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Li QC, Li QF, Wang YL, Sun HL and Jiang ZY: Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment. Int J Mol Med 41: 1635-1642, 2018.
APA
Li, Q., Li, Q., Wang, Y., Sun, H., & Jiang, Z. (2018). Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment. International Journal of Molecular Medicine, 41, 1635-1642. https://doi.org/10.3892/ijmm.2018.3365
MLA
Li, Q., Li, Q., Wang, Y., Sun, H., Jiang, Z."Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment". International Journal of Molecular Medicine 41.3 (2018): 1635-1642.
Chicago
Li, Q., Li, Q., Wang, Y., Sun, H., Jiang, Z."Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment". International Journal of Molecular Medicine 41, no. 3 (2018): 1635-1642. https://doi.org/10.3892/ijmm.2018.3365
Copy and paste a formatted citation
x
Spandidos Publications style
Li QC, Li QF, Wang YL, Sun HL and Jiang ZY: Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment. Int J Mol Med 41: 1635-1642, 2018.
APA
Li, Q., Li, Q., Wang, Y., Sun, H., & Jiang, Z. (2018). Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment. International Journal of Molecular Medicine, 41, 1635-1642. https://doi.org/10.3892/ijmm.2018.3365
MLA
Li, Q., Li, Q., Wang, Y., Sun, H., Jiang, Z."Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment". International Journal of Molecular Medicine 41.3 (2018): 1635-1642.
Chicago
Li, Q., Li, Q., Wang, Y., Sun, H., Jiang, Z."Arcuate nucleus neurons are not essential for the preprandial peak in plasma ghrelin after neonatal monosodium glutamate treatment". International Journal of Molecular Medicine 41, no. 3 (2018): 1635-1642. https://doi.org/10.3892/ijmm.2018.3365
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