|
1
|
Gao B and Bataller R: Alcoholic liver
disease: Pathogenesis and new therapeutic targets.
Gastroenterology. 141:1572–1585. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bryant CE, Spring DR, Gangloff M and Gay
NJ: The molecular basis of the host response to lipopolysaccharide.
Nat Rev Microbiol. 8:8–14. 2010. View Article : Google Scholar
|
|
3
|
Akira S and Takeda K: Toll-like receptor
signalling. Nat Rev Immunol. 4:499–511. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ding N, Zhang Y, Loughran PA, Wang Q,
Tsung A and Billiar TR: TIFA upregulation after
hypoxia-reoxygenation is TLR4- and MyD88-dependent and associated
with HMGB1 upregulation and release. Free Radic Biol Med.
63:361–367. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Wang X, Wang C, Wang J, Zhao S, Zhang K,
Wang J, Zhang W, Wu C and Yang J: Pseudoginsenoside-F11 (PF11)
exerts anti-neuroinflammatory effects on LPS-activated microglial
cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt
signaling pathways. Neuropharmacology. 79:642–656. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wang K: Molecular mechanisms of hepatic
apoptosis. Cell Death Dis. 5:e9962014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Modica S, Gadaleta RM and Moschetta A:
Deciphering the nuclear bile acid receptor FXR paradigm. Nucl
Recept Signal. 8:e0052010.PubMed/NCBI
|
|
8
|
Calkin AC and Tontonoz P: Transcriptional
integration of metabolism by the nuclear sterol-activated receptors
LXR and FXR. Nat Rev Mol Cell Biol. 13:213–224. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Wang YD, Chen WD, Wang M, Yu D, Forman BM
and Huang W: Farnesoid X receptor antagonizes nuclear factor kappaB
in hepatic inflammatory response. Hepatology. 48:1632–1643. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Yang F, Huang X, Yi T, Yen Y, Moore DD and
Huang W: Spontaneous development of liver tumors in the absence of
the bile acid receptor farnesoid X receptor. Cancer Res.
67:863–867. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kim I, Ahn SH, Inagaki T, Choi M, Ito S,
Guo GL, Kliewer SA and Gonzalez FJ: Differential regulation of bile
acid homeostasis by the farnesoid X receptor in liver and
intestine. J Lipid Res. 48:2664–2672. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yao J, Zhou CS, Ma X, Fu BQ1, Tao LS, Chen
M and Xu YP: FXR agonist GW4064 alleviates endotoxin-induced
hepatic inflammation by repressing macrophage activation. World J
Gastroenterol. 20:14430–14441. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang YD, Yang F, Chen WD, Huang X, Lai L,
Forman BM and Huang W: Farnesoid X receptor protects liver cells
from apoptosis induced by serum deprivation in vitro and fasting in
vivo. Mol Endocrinol. 22:1622–1632. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ito S, Tanaka Y, Oshino R, Okado S, Hori M
and Isobe KI: GADD34 suppresses lipopolysaccharide-induced sepsis
and tissue injury through the regulation of macrophage activation.
Cell Death Dis. 7:e22192016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Xiao HB, Sun ZL, Zhang HB and Zhang DS:
Berberine inhibits dyslipidemia in C57BL/6 mice with
lipopolysaccharide induced inflammation. Pharmacol Rep. 64:889–895.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Fiorucci S, Clerici C, Antonelli E,
Orlandi S, Goodwin B, Sadeghpour BM, Sabatino G, Russo G,
Castellani D, Willson TM, et al: Protective effects of 6-ethyl
chenodeoxycholic acid, a farnesoid X receptor ligand, in
estrogen-induced cholestasis. J pharmacol Exp Ther. 313:604–612.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Mencarelli A, Cipriani S, Renga B, D'Amore
C, Palladino G, Distrutti E, Baldelli F and Fiorucci S: FXR
activation improves myocardial fatty acid metabolism in a rodent
model of obesity-driven cardiotoxicity. Nutr Metab Cardiovasc Dis.
23:94–101. 2013. View Article : Google Scholar
|
|
18
|
Maloney PR, Parks DJ, Haffner CD, Fivush
AM, Chandra G, Plunket KD, Creech KL, Moore LB, Wilson JG, Lewis
MC, et al: Identification of a chemical tool for the orphan nuclear
receptor FXR. J Med Chem. 43:2971–2974. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhang DG, Zhang C, Wang JX, Wang BW, Wang
H, Zhang ZH, Chen YH, Lu Y, Tao L, Wang JQ, et al: Obeticholic acid
protects against carbon tetrachloride-induced acute liver injury
and inflammation. Toxicol App Pharmacol. 314:39–47. 2017.
View Article : Google Scholar
|
|
20
|
Takeuchi O and Akira S: Pattern
recognition receptors and inflammation. Cell. 140:805–820. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
McClain CJ, Barve S, Deaciuc I, Kugelmas M
and Hill D: Cytokines in alcoholic liver disease. Semin Liver Dis.
19:205–219. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Takeda K and Akira S: TLR signaling
pathways. Semin Immunol. 16:3–9. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Nagaleekar VK, Sabio G, Aktan I, Chant A,
Howe IW, Thornton TM, Benoit PJ, Davis RJ, Rincon M and Boyson JE:
Translational control of NKT cell cytokine production by p38 MAPK.
J Immunol. 186:4140–4146. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Allen K, Kim ND, Moon JO and Copple BL:
Upregulation of early growth response factor-1 by bile acids
requires mitogen-activated protein kinase signaling. Toxicol Appl
Pharmacol. 243:63–67. 2010. View Article : Google Scholar :
|
|
25
|
Xu Z, Huang G, Gong W, Zhou P, Zhao Y,
Zhang Y, Zeng Y, Gao M, Pan Z and He F: FXR ligands protect against
hepatocellular inflammation via SOCS3 induction. Cell Signal.
24:1658–1664. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Nolan JP: Intestinal endotoxins as
mediators of hepatic injury-an idea whose time has come again.
Hepatology. 10:887–891. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zhang P, Zhang M, Wan M, Huang X, Jiang Y,
Xu S and Luo M: Tamoxifen attenuates
lipopolysaccharide/galactosamine-induced acute liver failure by
antagonizing hepatic inflammation and apoptosis. Immunol Invest.
46:284–294. 2017. View Article : Google Scholar
|
|
28
|
Lian F, Wang Y, Xiao Y, Wu X, Xu H, Liang
L and Yang X: Activated farnesoid X receptor attenuates apoptosis
and liver injury in autoimmune hepatitis. Mol Med Rep.
12:5821–5827. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
McIlwain DR, Berger T and Mak TW: Caspase
functions in cell death and disease. Cold Spring Harb Perspect
Biol. 5:a0086562013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zollner G, Wagner M, Fickert P, Geier A,
Fuchsbichler A, Silbert D, Gumhold J, Zatloukal K, Kaser A, Tilg H,
et al: Role of nuclear receptors and hepatocyte-enriched
transcription factors for Ntcp repression in biliary obstruction in
mouse liver. Am J Physiol Gastrointest Liver Physiol.
289:G798–G805. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Zhang S, Wang J, Liu Q and Harnish DC:
Farnesoid X receptor agonist WAY-362450 attenuates liver
inflammation and fibrosis in murine model of non-alcoholic
steatohepatitis. J Hepatol. 51:380–388. 2009. View Article : Google Scholar : PubMed/NCBI
|
