|
1
|
Traystman RJ, Kirsch JR and Koehler RC:
Oxygen radical mechanisms of brain injury following ischemia and
reperfusion. J Appl Physiol (1985). 71:1185–1195. 1991. View Article : Google Scholar
|
|
2
|
Bramlett HM and Dietrich WD:
Pathophysiology of cerebral ischemia and brain trauma: Similarities
and differences. J Cereb Blood Flow Metab. 24:133–150. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Clemens JA: Cerebral ischemia: Gene
activation, neuronal injury, and the protective role of
antioxidants. Free Radic Biol Med. 28:1526–1531. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Chan PH: Reactive oxygen radicals in
signaling and damage in the ischemic brain. J Cereb Blood Flow
Metab. 21:2–14. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Lee EJ, Chen HY, Lee MY, Chen TY, Hsu YS,
Hu YL, Chang GL and Wu TS: Cinnamophilin reduces oxidative damage
and protects against transient focal cerebral ischemia in mice.
Free Radic Biol Med. 39:495–510. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lee EJ, Lee MY, Chen HY, Hsu YS, Wu TS,
Chen ST and Chang GL: Melatonin attenuates gray and white matter
damage in a mouse model of transient focal cerebral ischemia. J
Pineal Res. 38:42–52. 2005. View Article : Google Scholar
|
|
7
|
Shen YC, Sung YJ and Chen CF: Magnolol
inhibits Mac-1 (CD11b/CD18)-dependent neutrophil adhesion:
Relationship with its antioxidant effect. Eur J Pharmacol.
343:79–86. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wang Y, Li CY, Lin IH, Lee AR and Hu MK:
Synthesis and radical scavenging of novel magnolol derivatives. J
Pharm Pharmacol. 54:1697–1703. 2002. View Article : Google Scholar
|
|
9
|
Chen HY, Hung YC, Lee EJ, Chen TY, Chuang
IC and Wu TS: The protective efficacy of magnolol in hind limb
ischemia-reperfusion injury. Phytomedicine. 16:976–981. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chang CP, Hsu YC and Lin MT: Magnolol
protects against cerebral ischaemic injury of rat heatstroke. Clin
Exp Pharmacol Physiol. 30:387–392. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Teng CM, Yu SM, Chen CC, Huang YL and
Huang TF: EDRF-release and Ca+(+)-channel blockade by magnolol, an
antiplatelet agent isolated from Chinese herb Magnolia officinalis,
in rat thoracic aorta. Life Sci. 47:1153–1161. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Lee MM, Huang HM, Hsieh MT, Chen CS, Yeh
FT and Kuo JS: Anti-inflammatory and neuroprotective effects of
magnolol in chemical hypoxia in rat cultured cortical cells in
hypoglycemic media. Chin J Physiol. 43:61–67. 2000.PubMed/NCBI
|
|
13
|
Lee MM, Hseih MT, Kuo JS, Yeh FT and Huang
HM: Magnolol protects cortical neuronal cells from chemical hypoxia
in rats. Neuroreport. 9:3451–3456. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lin YR, Chen HH, Ko CH and Chan MH:
Neuroprotective activity of honokiol and magnolol in cerebellar
granule cell damage. Eur J Pharmacol. 537:64–69. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Lee WT, Lin MH, Lee EJ, Hung YC, Tai SH,
Chen HY, Chen TY and Wu TS: Magnolol reduces glutamate-induced
neuronal excitotoxicity and protects against permanent focal
cerebral ischemia up to 4 hours. PLoS One. 7:e399522012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Watanabe K, Watanabe H, Goto Y, Yamaguchi
M, Yamamoto N and Hagino K: Pharmacological properties of magnolol
and honokiol extracted from Magnolia officinalis: Central
depressant effects. Planta Med. 49:103–108. 1983. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lin SP, Tsai SY, Lee Chao PD, Chen YC and
Hou YC: Pharmacokinetics, bioavailability, and tissue distribution
of magnolol following single and repeated dosing of magnolol to
rats. Planta Med. 77:1800–1805. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Chapman SN, Mehndiratta P, Johansen MC,
McMurry TL, Johnston KC and Southerland AM: Current perspectives on
the use of intravenous recombinant tissue plasminogen activator
(tPA) for treatment of acute ischemic stroke. Vasc Health Risk
Manag. 10:75–87. 2014.PubMed/NCBI
|
|
19
|
Lee EJ, Chen HY, Hung YC, Chen TY, Lee MY,
Yu SC, Chen YH, Chuang IC and Wu TS: Therapeutic window for
cinnamophilin following oxygen-glucose deprivation and transient
focal cerebral ischemia. Exp Neurol. 217:74–83. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chen TY, Lin MH, Lee WT, Huang SY, Chen
YH, Lee AC, Lin HW and Lee EJ: Nicotinamide inhibits nuclear
factor-kappa B translocation after transient focal cerebral
ischemia. Crit Care Med. 40:532–537. 2012. View Article : Google Scholar
|
|
21
|
Tai SH, Hung YC, Lee EJ, Lee AC, Chen TY,
Shen CC, Chen HY, Lee MY, Huang SY and Wu TS: Melatonin protects
against transient focal cerebral ischemia in both reproductively
active and estrogen-deficient female rats: The impact of
circulating estrogen on its hormetic dose-response. J Pineal Res.
50:292–303. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Chen TY, Tai SH, Lee EJ, Huang CC, Lee AC,
Huang SY and Wu TS: Cinnamophilin offers prolonged neuroprotection
against gray and white matter damage and improves functional and
electrophysiological outcomes after transient focal cerebral
ischemia. Crit Care Med. 39:1130–1137. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Juan WS, Huang SY, Chang CC, Hung YC, Lin
YW, Chen TY, Lee AH, Lee AC, Wu TS and Lee EJ: Melatonin improves
neuroplasticity by upregulating the growth-associated protein-43
(GAP-43) and NMDAR postsynaptic density-95 (PSD-95) proteins in
cultured neurons exposed to glutamate excitotoxicity and in rats
subjected to transient focal cerebral ischemia even during a
long-term recovery period. J Pineal Res. 56:213–223. 2014.
View Article : Google Scholar
|
|
24
|
Anderson ME: Determination of glutathione
and glutathione disulfide in biological samples. Methods Enzymol.
113:548–555. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Belayev L, Alonso OF, Busto R, Zhao W and
Ginsberg MD: Middle cerebral artery occlusion in the rat by
intraluminal suture. Neurological and pathological evaluation of an
improved model. Stroke. 27:1616–1623. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Clark WM, Rinker LG, Lessov NS, Hazel K,
Hill JK, Stenzel-Poore M and Eckenstein F: Lack of interleukin-6
expression is not protective against focal central nervous system
ischemia. Stroke. 31:1715–1720. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Hsieh MT, Chueh FY and Lin MT: Magnolol
decreases body temperature by reducing 5-hydroxytryptamine release
in the rat hypothalamus. Clin Exp Pharmacol Physiol. 25:813–817.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Danton GH and Dietrich WD: Inflammatory
mechanisms after ischemia and stroke. J Neuropathol Exp Neurol.
62:127–136. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ishikawa M, Sekizuka E, Sato S, Yamaguchi
N, Inamasu J, Bertalanffy H, Kawase T and Iadecola C: Effects of
moderate hypothermia on leukocyte-endothelium interaction in the
rat pial microvasculature after transient middle cerebral artery
occlusion. Stroke. 30:1679–1686. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Nakashima M, Niwa M, Iwai T and Uematsu T:
Involvement of free radicals in cerebral vascular reperfusion
injury evaluated in a transient focal cerebral ischemia model of
rat. Free Radic Biol Med. 26:722–729. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Sugawara T and Chan PH: Reactive oxygen
radicals and pathogenesis of neuronal death after cerebral
ischemia. Antioxid Redox Signal. 5:597–607. 2003. View Article : Google Scholar : PubMed/NCBI
|
