|
1
|
Shiba Y, Gomibuchi T, Seto T, Wada Y,
Ichimura H, Tanaka Y, Ogasawara T, Okada K, Shiba N, Sakamoto K, et
al: Allogeneic transplantation of iPS cell-derived cardiomyocytes
regenerates primate hearts. Nature. 538:388–391. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hanna JH, Saha K and Jaenisch R:
Pluripotency and cellular reprogramming: facts, hypotheses,
unresolved issues. Cell. 143:508–525. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X,
Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, et al: Synaptic
dysregulation in a human iPS cell model of mental disorders.
Nature. 515:414–418. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Bakken TE, Miller JA, Ding SL, Sunkin SM,
Smith KA, Ng L, Szafer A, Dalley RA, Royall JJ, Lemon T, et al: A
comprehensive transcriptional map of primate brain development.
Nature. 535:367–375. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Charrier JB, Lapointe F, Le Douarin NM and
Teillet MA: Dual origin of the floor plate in the avian embryo.
Development. 129:4785–4796. 2002.PubMed/NCBI
|
|
6
|
Yan Y, Bejoy J, Xia J, Guan J, Zhou Y and
Li Y: Neural patterning of human induced pluripotent stem cells in
3-D cultures for studying biomolecule-directed differential
cellular responses. Acta Biomater. 42:114–126. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Brennand K, Savas JN, Kim Y, Tran N,
Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran
I, et al: Phenotypic differences in hiPSC NPCs derived from
patients with schizophrenia. Mol Psychiatry. 20:361–368. 2015.
View Article : Google Scholar
|
|
8
|
Davila J, Chanda S, Ang CE, Südhof TC and
Wernig M: Acute reduction in oxygen tension enhances the induction
of neurons from human fibroblasts. J Neurosci Methods. 216:104–109.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Liu F, Xuan A, Chen Y, Zhang J, Xu L, Yan
Q and Long D: Combined effect of nerve growth factor and brain
derived neurotrophic factor on neuronal differentiation of neural
stem cells and the potential molecular mechanisms. Mol Med Rep.
10:1739–1745. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Metcalfe SM: LIF in the regulation of
T-cell fate and as a potential therapeutic. Genes Immun.
12:157–168. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yue X, Wu L and Hu W: The regulation of
leukemia inhibitory factor. Cancer Cell Microenviron.
2:e8772015.
|
|
12
|
Burdon T, Smith A and Savatier P:
Signalling, cell cycle and pluripotency in embryonic stem cells.
Trends Cell Biol. 12:432–438. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Pera MF and Tam PP: Extrinsic regulation
of pluripotent stem cells. Nature. 465:713–720. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Li X, Yang Q, Yu H, Wu L, Zhao Y, Zhang C,
Yue X, Liu Z, Wu H, Haffty BG, et al: LIF promotes tumorigenesis
and metastasis of breast cancer through the AKT-mTOR pathway.
Oncotarget. 5:788–801. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Liu SC, Tsang NM, Chiang WC, Chang KP,
Hsueh C, Liang Y, Juang JL, Chow KP and Chang YS: Leukemia
inhibitory factor promotes nasopharyngeal carcinoma progression and
radioresistance. J Clin Invest. 123:5269–5283. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kanda M, Nagai T, Takahashi T, Liu ML,
Kondou N, Naito AT, Akazawa H, Sashida G, Iwama A, Komuro I, et al:
Leukemia inhibitory factor enhances endogenous cardiomyocyte
regeneration after myocardial infarction. PLoS One.
11:e01565622016. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Laszlo GS and Nathanson NM: Src family
kinase-independent signal transduction and gene induction by
leukemia inhibitory factor. J Biol Chem. 278:27750–27757. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Morell C, Bort A, Vara D, Ramos-Torres A,
Rodríguez-Henche N and Díaz-Laviada I: The cannabinoid WIN 55,212-2
prevents neuroendocrine differentiation of LNCaP prostate cancer
cells. Prostate Cancer Prostatic Dis. 19:248–257. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhang Y, He Q, Dong J, Jia Z, Hao F and
Shan C: Effects of epigallocatechin-3-gallate on proliferation and
differentiation of mouse cochlear neural stem cells: involvement of
PI3K/Akt signaling pathway. Eur J Pharm Sci. 88:267–273. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Murphy M, Reid K, Hilton DJ and Bartlett
PF: Generation of sensory neurons is stimulated by leukemia
inhibitory factor. Proc Natl Acad Sci USA. 88:3498–3501. 1991.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Li Y and Zang D: The neuron regrowth is
associated with the proliferation of neural precursor cells after
leukemia inhibitory factor administration following spinal cord
injury in mice. PLoS One. 9:e1160312014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Lin C, Lin HY, Chen JH, Tseng WP, Ko PY,
Liu YS, Yeh WL and Lu DY: Effects of paeonol on
anti-neuroinflammatory responses in microglial cells. Int J Mol
Sci. 16:8844–8860. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Fu SP, Wang JF, Xue WJ, Liu HM, Liu BR,
Zeng YL, Li SN, Huang BX, Lv QK, Wang W, et al: Anti-inflammatory
effects of BHBA in both in vivo and in vitro Parkinson's disease
models are mediated by GPR109A-dependent mechanisms. J
Neuroinflammation. 12:2015. View Article : Google Scholar
|
|
24
|
Jing Yh, Hou Yp, Song Yf and Yin J:
Methylprednisolone improves the survival of new neurons following
transient cerebral ischemia in rats. Acta Neurobiol Exp (Wars).
72:240–252. 2012.
|
|
25
|
Tentillier N, Etzerodt A, Olesen MN,
Rizalar FS, Jacobsen J, Bender D, Moestrup SK and Romero-Ramos M:
Anti-inflammatory modulation of microglia via CD163-targeted
glucocorticoids protects dopaminergic neurons in the 6-OHDA
Parkinson's disease model. J Neurosci. 36:9375–9390. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Pal R, Tiwari PC, Nath R and Pant KK: Role
of neuroinflammation and latent transcription factors in
pathogenesis of Parkinson's disease. Neurol Res. 38:1111–1122.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Ulich TR, Fann MJ, Patterson PH, Williams
JH, Samal B, Del Castillo J, Yin S, Guo K and Remick DG:
Intratracheal injection of LPS and cytokines. V. LPS induces
expression of LIF and LIF inhibits acute inflammation. Am J
Physiol. 267:L442–L446. 1994.PubMed/NCBI
|
|
28
|
Knight DA, Lydell CP, Zhou D, Weir TD,
Robert Schellenberg R and Bai TR: Leukemia inhibitory factor (LIF)
and LIF receptor in human lung. Distribution and regulation of LIF
release. Am J Respir Cell Mol Biol. 20:834–841. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Palmqvist P, Lundberg P, Lundgren I,
Hänström L and Lerner UH: IL-1beta and TNF-alpha regulate IL-6-type
cytokines in gingival fibroblasts. J Dent Res. 87:558–563. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kong Q, Zhang H, Zhao T, Zhang W, Yan M,
Dong X and Li P: Tangshen formula attenuates hepatic steatosis by
inhibiting hepatic lipogenesis and augmenting fatty acid oxidation
in db/db mice. Int J Mol Med. 38:1715–1726. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−ΔΔC(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar
|
|
32
|
Chen E, Xu D, Lan X, Jia B, Sun L, Zheng
JC and Peng H: A novel role of the STAT3 pathway in brain
inflammation-induced human neural progenitor cell differentiation.
Curr Mol Med. 13:1474–1484. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Li YH, Fu HL, Tian ML, Wang YQ, Chen W,
Cai LL, Zhou XH and Yuan HB: Neuron-derived FGF10 ameliorates
cerebral ischemia injury via inhibiting NF-κB-dependent
neuroinflammation and activating PI3K/Akt survival signaling
pathway in mice. Sci Rep. 6:198692016. View Article : Google Scholar
|
|
34
|
Chau MJ, Deveau TC, Song M, Gu X, Chen D
and Wei L: iPSC transplantation increases regeneration and
functional recovery after ischemic stroke in neonatal rats. Stem
Cells. 32:3075–3087. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Chen C, Wang Y, Goh SS, Yang J, Lam DH,
Choudhury Y, Tay FC, Du S, Tan WK, Purwanti YI, et al: Inhibition
of neuronal nitric oxide synthase activity promotes migration of
human-induced pluripotent stem cell-derived neural stem cells
toward cancer cells. J Neurochem. 126:318–330. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Meneghini V, Frati G, Sala D, De Cicco S,
Luciani M, Cavazzin C, Paulis M, Mentzen W, Morena F, Giannelli S,
et al: Generation of human induced pluripotent stem cell-derived
bona fide neural stem cells for ex vivo gene therapy of
metachromatic leukodystrophy. Stem Cells Transl Med. 6:352–368.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Chambers SM, Qi Y, Mica Y, Lee G, Zhang
XJ, Niu L, Bilsland J, Cao L, Stevens E, Whiting P, et al: Combined
small-molecule inhibition accelerates developmental timing and
converts human pluripotent stem cells into nociceptors. Nat
Biotechnol. 30:715–720. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kirby ML, Kumiski DH, Myers T, Cerjan C
and Mishima N: Backtransplantation of chick cardiac neural crest
cells cultured in LIF rescues heart development. Dev Dyn.
198:296–311. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Laterza C, Merlini A, De Feo D, Ruffini F,
Menon R, Onorati M, Fredrickx E, Muzio L, Lombardo A, Comi G, et
al: iPSC-derived neural precursors exert a neuroprotective role in
immune-mediated demyelination via the secretion of LIF. Nat Commun.
4:25972013. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Yan T, Yu X, Sun X, Meng D and Jia JM: A
new steroidal saponin, furotrilliumoside from Trillium tschonoskii
inhibits lipopolysaccharide-induced inflammation in Raw264.7 cells
by targeting PI3K/Akt, MARK and Nrf2/HO-1 pathways. Fitoterapia.
115:37–45. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Chien MY, Chuang CH, Chern CM, Liou KT,
Liu DZ, Hou YC and Shen YC: Salvianolic acid A alleviates ischemic
brain injury through the inhibition of inflammation and apoptosis
and the promotion of neurogenesis in mice. Free Radic Biol Med.
99:508–519. 2016. View Article : Google Scholar : PubMed/NCBI
|
