|
1
|
Ware LB and Matthay MA: The acute
respiratory distress syndrome. N Engl J Med. 342:1334–1349. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Matthay MA and Zimmerman GA: Acute lung
injury and the acute respiratory distress syndrome: Four decades of
inquiry into pathogenesis and rational management. Am J Respir Cell
Mol Biol. 33:319–327. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Matthay MA, Ware LB and Zimmerman GA: The
acute respiratory distress syndrome. J Clin Invest. 122:2731–2740.
2012. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Li G, Malinchoc M, Cartin-Ceba R, Venkata
CV, Kor DJ, Peters SG, Hubmayr RD and Gajic O: Eight-year trend of
acute respiratory distress syndrome: A population-based study in
Olmsted County, Minnesota. Am J Respir Crit Care Med. 183:59–66.
2011. View Article : Google Scholar :
|
|
5
|
Rubenfeld GD, Caldwell E, Peabody E,
Weaver J, Martin DP, Neff M, Stern EJ and Hudson LD: Incidence and
outcomes of acute lung injury. N Engl J Med. 353:1685–1693. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Tsushima K, King LS, Aggarwal NR, De
Gorodo A, D'Alessio FR and Kubo K: Acute lung injury review. Intern
Med. 48:621–630. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Moya IM and Halder G: Hippo-YAP/TAZ
signalling in organ regeneration and regenerative medicine. Nat Rev
Mol Cell Biol. 20:211–226. 2019. View Article : Google Scholar
|
|
8
|
Zhao B, Tumaneng K and Guan KL: The Hippo
pathway in organ size control, tissue regeneration and stem cell
self-renewal. Nat Cell Biol. 13:877–883. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Dong J, Feldmann G, Huang J, Wu S, Zhang
N, Comerford SA, Gayyed MF, Anders RA, Maitra A and Pan D:
Elucidation of a universal size-control mechanism in Drosophila and
mammals. Cell. 130:1120–1133. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Xie H, Wu L, Deng Z, Huo Y and Cheng Y:
Emerging roles of YAP/TAZ in lung physiology and diseases. Life
Sci. 214:176–183. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Xin M, Kim Y, Sutherland LB, Murakami M,
Qi X, McAnally J, Porrello ER, Mahmoud AI, Tan W, Shelton JM, et
al: Hippo pathway effector Yap promotes cardiac regeneration. Proc
Natl Acad Sci USA. 110:13839–13844. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Wu S, Liu Y, Zheng Y, Dong J and Pan D:
The TEAD/TEF family protein Scalloped mediates transcriptional
output of the Hippo growth-regulatory pathway. Dev Cell.
14:388–398. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang X, Freire Valls A, Schermann G, Shen
Y, Moya IM, Castro L, Urban S, Solecki GM, Winkler F, Riedemann L,
et al: YAP/TAZ Orchestrate VEGF signaling during developmental
angiogenesis. Dev Cell. 42:462–478.e7. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Elaimy AL and Mercurio AM: Convergence of
VEGF and YAP/TAZ signaling: Implications for angiogenesis and
cancer biology. Sci Signal. 11:eaau11652018. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Piccolo S, Dupont S and Cordenonsi M: The
biology of YAP/TAZ: Hippo signaling and beyond. Physiol Rev.
94:1287–1312. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Gumbiner BM and Kim NG: The Hippo-YAP
signaling pathway and contact inhibition of growth. J Cell Sci.
127:709–717. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Saito A and Nagase T: Hippo and TGF-β
interplay in the lung field. Am J Physiol Lung Cell Mol Physiol.
309:L756–L767. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhou B, Flodby P, Luo J, Castillo DR, Liu
Y, Yu FX, McConnell A, Varghese B, Li G, Chimge NO, et al:
Claudin-18-mediated YAP activity regulates lung stem and progenitor
cell homeostasis and tumorigenesis. J Clin Invest. 128:970–984.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lange AW, Sridharan A, Xu Y, Stripp BR,
Perl AK and Whitsett JA: Hippo/Yap signaling controls epithelial
progenitor cell proliferation and differentiation in the embryonic
and adult lung. J Mol Cell Biol. 7:35–47. 2015. View Article : Google Scholar :
|
|
20
|
Volckaert T, Yuan T, Yuan J, Boateng E,
Hopkins S, Zhang JS, Thannickal VJ, Fässler R and De Langhe SP:
Hippo signaling promotes lung epithelial lineage commitment by
curbing Fgf10 and β-catenin signaling. Development.
146:dev1664542019. View Article : Google Scholar
|
|
21
|
Zhao R, Fallon TR, Saladi SV,
Pardo-Saganta A, Villoria J, Mou H, Vinarsky V, Gonzalez-Celeiro M,
Nunna N, Hariri LP, et al: Yap tunes airway epithelial size and
architecture by regulating the identity, maintenance, and
self-renewal of stem cells. Dev Cell. 30:151–165. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Azad T, Ghahremani M and Yang X: The role
of YAP and TAZ in angiogenesis and vascular mimicry. Cells.
8:4072019. View Article : Google Scholar :
|
|
23
|
Choi HJ, Zhang H, Park H, Choi KS, Lee HW,
Agrawal V, Kim YM and Kwon YG: Yes-associated protein regulates
endothelial cell contact-mediated expression of angiopoietin-2. Nat
Commun. 6:69432015. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Sharif GM, Schmidt MO, Yi C, Hu Z, Haddad
BR, Glasgow E, Riegel AT and Wellstein A: Cell growth density
modulates cancer cell vascular invasion via Hippo pathway activity
and CXCR2 signaling. Oncogene. 34:5879–5889. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zhao B, Li L, Wang L, Wang CY, Yu J and
Guan KL: Cell detachment activates the Hippo pathway via
cytoskeleton reorganization to induce anoikis. Genes Dev. 26:54–68.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Liu F, Lagares D, Choi KM, Stopfer L,
Marinković A, Vrbanac V, Probst CK, Hiemer SE, Sisson TH, Horowitz
JC, et al: Mechanosignaling through YAP and TAZ drives fibroblast
activation and fibrosis. Am J Physiol Lung Cell Mol Physiol.
308:L344–L357. 2015. View Article : Google Scholar :
|
|
27
|
Chung C, Kim T, Kim M, Kim M, Song H, Kim
TS, Seo E, Lee SH, Kim H, Kim SK, et al: Hippo-Foxa2 signaling
pathway plays a role in peripheral lung maturation and surfactant
homeostasis. Proc Natl Acad Sci USA. 110:7732–7737. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Mindos T, Dun XP, North K, Doddrell RD,
Schulz A, Edwards P, Russell J, Gray B, Roberts SL, Shivane A, et
al: Merlin controls the repair capacity of Schwann cells after
injury by regulating Hippo/YAP activity. J Cell Biol. 216:495–510.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Liu Y, Lu T, Zhang C, Xu J, Xue Z,
Busuttil RW, Xu N, Xia Q, Kupiec-Weglinski JW and Ji H: Activation
of YAP attenuates hepatic damage and fibrosis in liver
ischemia-reperfusion injury. J Hepatol. 71:719–730. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Li L, Dong L, Zhang J, Gao F, Hui J and
Yan J: Mesenchymal stem cells with downregulated Hippo signaling
attenuate lung injury in mice with lipopolysaccharide-induced acute
respiratory distress syndrome. Int J Mol Med. 43:1241–1252.
2019.PubMed/NCBI
|
|
31
|
Volckaert T, Yuan T, Chao CM, Bell H,
Sitaula A, Szimmtenings L, El Agha E, Chanda D, Majka S, Bellusci
S, et al: Fgf10-Hippo epithelial-mesenchymal crosstalk maintains
and recruits lung basal stem cells. Dev Cell. 43:48–59.e5. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
LaCanna R, Liccardo D, Zhang P, Tragesser
L, Wang Y, Cao T, Chapman HA, Morrisey EE, Shen H, Koch WJ, et al:
Yap/Taz regulate alveolar regeneration and resolution of lung
inflammation. J Clin Invest. 129:2107–2122. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Hu C, Sun J, Du J, Wen D, Lu H, Zhang H,
Xue Y, Zhang A, Yang C, Zeng L and Jiang J: The Hippo-YAP pathway
regulates the proliferation of alveolar epithelial progenitors
after acute lung injury. Cell Biol Int. 43:1174–1183. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Bhattacharya J and Matthay MA: Regulation
and repair of the alveolar-capillary barrier in acute lung injury.
Annu Rev Physiol. 75:593–615. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Crosby LM and Waters CM: Epithelial repair
mechanisms in the lung. Am J Physiol Lung Cell Mol Physiol.
298:L715–L731. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Frank JA: Claudins and alveolar epithelial
barrier function in the lung. Ann N Y Acad Sci. 1257:175–183. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Liu G, Ye X, Miller EJ and Liu SF:
NF-κB-to-AP-1 switch: A mechanism regulating transition from
endothelial barrier injury to repair in endotoxemic mice. Sci Rep.
4:55432014. View Article : Google Scholar
|
|
38
|
Mao SZ, Ye X, Liu G, Song D and Liu SF:
Resident endothelial cells and endothelial progenitor cells restore
endothelial barrier function after inflammatory lung injury.
Arterioscler Thromb Vasc Biol. 35:1635–1644. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
National Research Council (US) Committee
for the Update of the Guide for the Care and Use of Laboratory
Animals: Guide for the Care and Use of Laboratory Animals. 8th
edition. National Academies Press (US); Washington, DC: 2011
|
|
40
|
Fan F, He Z, Kong LL, Chen Q, Yuan Q,
Zhang S, Ye J, Liu H, Sun X, Geng J, et al: Pharmacological
targeting of kinases MST1 and MST2 augments tissue repair and
regeneration. Sci Transl Med. 8:352ra1082016. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
42
|
Ye X, Ding J, Zhou X, Chen G and Liu SF:
Divergent roles of endothelial NF-kappaB in multiple organ injury
and bacterial clearance in mouse models of sepsis. J Exp Med.
205:1303–1315. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Liu SF, Ye X and Malik AB: In vivo
inhibition of nuclear factor-kappa B activation prevents inducible
nitric oxide synthase expression and systemic hypotension in a rat
model of septic shock. J Immunol. 159:3976–3983. 1997.PubMed/NCBI
|
|
44
|
Liu-Chittenden Y, Huang B, Shim JS, Chen
Q, Lee SJ, Anders RA, Liu JO and Pan D: Genetic and pharmacological
disruption of the TEAD-YAP complex suppresses the oncogenic
activity of YAP. Genes Dev. 26:1300–1305. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Williams MC: Alveolar type I cells:
Molecular phenotype and development. Annu Rev Physiol. 65:669–695.
2003. View Article : Google Scholar
|
|
46
|
Rippon HJ, Ali NN, Polak JM and Bishop AE:
Initial observations on the effect of medium composition on the
differentiation of murine embryonic stem cells to alveolar type II
cells. Cloning Stem Cells. 6:49–56. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Bruser L and Bogdan S: Adherens junctions
on the move-membrane trafficking of E-cadherin. Cold Spring Harb
Perspect Biol. 9:a0291402017. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Rezaee F and Georas SN: Breaking barriers.
New insights into airway epithelial barrier function in health and
disease. Am J Respir Cell Mol Biol. 50:857–869. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Kim J, Kim YH, Kim J, Park DY, Bae H, Lee
DH, Kim KH, Hong SP, Jang SP, Kubota Y, et al: YAP/TAZ regulates
sprouting angiogenesis and vascular barrier maturation. J Clin
Invest. 127:3441–3461. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Neto F, Klaus-Bergmann A, Ong YT, Alt S,
Vion AC, Szymborska A, Carvalho JR, Hollfinger I, Bartels-Klein E,
Franco CA, et al: YAP and TAZ regulate adherens junction dynamics
and endothelial cell distribution during vascular development.
Elife. 7:e310372018. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Harris TJ and Tepass U: Adherens
junctions: From molecules to morphogenesis. Nat Rev Mol Cell Biol.
11:502–514. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Lv Y, Kim K, Sheng Y, Cho J, Qian Z, Zhao
YY and Hu G, Pan D, Malik AB and Hu G: YAP controls endothelial
activation and vascular inflammation through TRAF6. Circ Res.
123:43–56. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Ramjee V, Li D, Manderfield LJ, Liu F,
Engleka KA, Aghajanian H, Rodell CB, Lu W, Ho V, Wang T, et al:
Epicardial YAP/TAZ orchestrate an immunosuppressive response
following myocardial infarction. J Clin Invest. 127:899–911. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Wang L, Luo JY, Li B, Tian XY, Chen LJ,
Huang Y, Liu J, Deng D, Lau CW, Wan S, et al: Integrin-YAP/TAZ-JNK
cascade mediates atheroprotective effect of unidirectional shear
flow. Nature. 540:579–582. 2016. View Article : Google Scholar : PubMed/NCBI
|
