|
1.
|
Merika E, Saif MW, Katz A, Syrigos K and
Morse M: Review. Colon cancer vaccines: an update. In Vivo.
24:607–628. 2010.PubMed/NCBI
|
|
2.
|
Cunningham D, Atkin W, Lenz HJ, et al:
Colorectal cancer. Lancet. 375:1030–1047. 2010. View Article : Google Scholar
|
|
3.
|
Jung KW, Won YJ, Kong HJ, Oh CM, Seo HG
and Lee JS: Prediction of cancer incidence and mortality in Korea,
2013. Cancer Res Treat. 45:15–21. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
4.
|
Luu C, Arrington AK, Schoellhammer HF,
Singh G and Kim J: Targeted therapies in colorectal cancer:
surgical considerations. J Gastrointest Oncol. 4:328–336.
2013.PubMed/NCBI
|
|
5.
|
Lopez-Lazaro M, Willmore E and Austin CA:
The dietary flavonoids myricetin and fisetin act as dual inhibitors
of DNA topoisomerases I and II in cells. Mutat Res. 696:41–47.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
6.
|
Cao G, Sofic E and Prior RL: Antioxidant
and prooxidant behavior of flavonoids: structure-activity
relationships. Free Radic Biol Med. 22:749–760. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
7.
|
Constantinou A, Mehta R, Runyan C, Rao K,
Vaughan A and Moon R: Flavonoids as DNA topoisomerase antagonists
and poisons: structure-activity relationships. J Nat Prod.
58:217–225. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
8.
|
Patra N, De U, Kang JA, et al: A novel
epoxypropoxy flavonoid derivative and topoisomerase II inhibitor,
MHY336, induces apoptosis in prostate cancer cells. Eur J
Pharmacol. 658:98–107. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9.
|
Jeong JH, Kang SS, Park KK, Chang HW,
Magae J and Chang YC: p53-independent induction of G1 arrest and
p21WAF1/CIP1 expression by ascofuranone, an isoprenoid
antibiotic, through downregulation of c-Myc. Mol Cancer Ther.
9:2102–2113. 2010.PubMed/NCBI
|
|
10.
|
Oliner JD, Kinzler KW, Meltzer PS, George
DL and Vogelstein B: Amplification of a gene encoding a
p53-associated protein in human sarcomas. Nature. 358:80–83. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
11.
|
Kastan MB, Zhan Q, el-Deiry WS, et al: A
mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is
defective in ataxia-telangiectasia. Cell. 71:587–597. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
12.
|
Miyashita T and Reed JC: Tumor suppressor
p53 is a direct transcriptional activator of the human bax gene.
Cell. 80:293–299. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
13.
|
Harper JW, Adami GR, Wei N, Keyomarsi K
and Elledge SJ: The p21 Cdk-interacting protein Cip1 is a potent
inhibitor of G1 cyclin-dependent kinases. Cell. 75:805–816. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
14.
|
Xiong Y, Hannon GJ, Zhang H, Casso D,
Kobayashi R and Beach D: p21 is a universal inhibitor of cyclin
kinases. Nature. 366:701–704. 1993. View
Article : Google Scholar : PubMed/NCBI
|
|
15.
|
Waldman T, Kinzler KW and Vogelstein B:
p21 is necessary for the p53-mediated G1 arrest in human cancer
cells. Cancer Res. 55:5187–5190. 1995.PubMed/NCBI
|
|
16.
|
Agrawal S, Agarwal ML, Chatterjee-Kishore
M, Stark GR and Chisolm GM: Stat1-dependent, p53-independent
expression of p21 (waf1) modulates oxysterol-induced apoptosis. Mol
Cell Biol. 22:1981–1992. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
17.
|
Aneja R, Ghaleb AM, Zhou J, Yang VW and
Joshi HC: p53 and p21 determine the sensitivity of
noscapine-induced apoptosis in colon cancer cells. Cancer Res.
67:3862–3870. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18.
|
Haldar S, Negrini M, Monne M, Sabbioni S
and Croce CM: Downregulation of bcl-2 by p53 in breast cancer
cells. Cancer Res. 54:2095–2097. 1994.PubMed/NCBI
|
|
19.
|
Wang XW and Harris CC: p53
tumor-suppressor gene: clues to molecular carcinogenesis. J Cell
Physiol. 173:247–255. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
20.
|
Niculescu AB III, Chen X, Smeets M, Hengst
L, Prives C and Reed SI: Effects of p21 (Cip1/Waf1) at both the
G1/S and the G2/M cell cycle transitions: pRb is a critical
determinant in blocking DNA replication and in preventing
endoreduplication. Mol Cell Biol. 18:629–643. 1998.PubMed/NCBI
|
|
21.
|
Baus F, Gire V, Fisher D, Piette J and
Dulic V: Permanent cell cycle exit in G2 phase after DNA damage in
normal human fibroblasts. EMBO J. 22:3992–4002. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
22.
|
el-Deiry WS, Tokino T, Velculescu VE, et
al: WAF1, a potential mediator of p53 tumor suppression. Cell.
75:817–825. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
23.
|
Gartel AL and Tyner AL: Transcriptional
regulation of the p21(WAF1/CIP1) gene. Exp Cell Res. 246:280–289.
1999. View Article : Google Scholar : PubMed/NCBI
|
|
24.
|
Haupt S, Berger M, Goldberg Z and Haupt Y:
Apoptosis - the p53 network. J Cell Sci. 116:4077–4085. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
25.
|
Sandri MI, Isaacs RJ, Ongkeko WM, et al:
p53 regulates the minimal promoter of the human topoisomerase
IIalpha gene. Nucleic Acids Res. 24:4464–4470. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
26.
|
Wang Q, Zambetti GP and Suttle DP:
Inhibition of DNA topoisomerase II alpha gene expression by the p53
tumor suppressor. Mol Cell Biol. 17:389–397. 1997.PubMed/NCBI
|
|
27.
|
Valkov NI and Sullivan DM: Tumor p53
status and response to topoisomerase II inhibitors. Drug Resist
Updat. 6:27–39. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
28.
|
Yang SY, Sales KM, Fuller B, Seifalian AM
and Winslet MC: Apoptosis and colorectal cancer: implications for
therapy. Trends Mol Med. 15:225–233. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29.
|
Peter ME: The flip side of FLIP. Biochem
J. 382:e1–e3. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
30.
|
Ashkenazi A: Targeting the extrinsic
apoptosis pathway in cancer. Cytokine Growth Factor Rev.
19:325–331. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
31.
|
Cory S and Adams JM: The Bcl2 family:
regulators of the cellular life-or-death switch. Nat Rev Cancer.
2:647–656. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
32.
|
Kuwana T, Mackey MR, Perkins G, et al:
Bid, Bax, and lipids cooperate to form supramolecular openings in
the outer mitochondrial membrane. Cell. 111:331–342. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
33.
|
Oliver L and Vallette FM: The role of
caspases in cell death and differentiation. Drug Resist Updat.
8:163–170. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
34.
|
Iannolo G, Conticello C, Memeo L and De
Maria R: Apoptosis in normal and cancer stem cells. Crit Rev Oncol
Hematol. 66:42–51. 2008. View Article : Google Scholar : PubMed/NCBI
|
