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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
2014-March Volume 44 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Fascin1 expression in high-grade serous ovarian carcinoma is a prognostic marker and knockdown of fascin1 suppresses the proliferation of ovarian cancer cells

Sae Hyun Park, Ji-Ye Song, Yu-Kyung Kim, Jin Hyung Heo, Haeyoun Kang, Gwangil Kim, Hee Jung An, Tae Hoen Kim
Pages: 637-646
Published online on: 30 December 2013

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Article Open Access

Increased SNAIL expression and low syndecan levels are associated with high Gleason grade in prostate cancer

Cristian E. Poblete, Juan Fulla, Marcela Gallardo, Valentina Muñoz, Enrique A. Castellón, Ivan Gallegos, Hector R. Contreras
Pages: 647-654
Published online on: 10 January 2014

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Article Open Access

GLI1 upregulates C-JUN through a specific 130-kDa isoform

Lauren Amable, Elaine Gavin, Kenji Kudo, Erhong Meng, Rodney P. Rocconi, Lalita A. Shevde, Eddie Reed
Pages: 655-661
Published online on: 20 December 2013

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Article Open Access

Phase I clinical trial of peptide vaccination with URLC10 and VEGFR1 epitope peptides in patients with advanced gastric cancer

Yoshie Higashihara, Junko Kato, Akihito Nagahara, Kentaro Izumi, Masae Konishi, Tomohiro Kodani, Nobuko Serizawa, Taro Osada, Sumio Watanabe
Pages: 662-668
Published online on: 31 December 2013

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Article

Molecular characterization of CD133+ cancer stem-like cells in endometrial cancer

Mitsuhiro Nakamura, Xiuzhi Zhang, Yasunari Mizumoto, Yoshiko Maida, Yukiko Bono, Masahiro Takakura, Satoru Kyo
Pages: 669-677
Published online on: 23 December 2013

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Article

Functional mononucleotide repeat polymorphism in the promoter region of HGF is associated with risk and malignant aggressiveness of bladder cancer

Syuji Chiba, Norihiko Tsuchiya, Yohei Horikawa, Shintaro Narita, Takamitsu Inoue, Susumu Akihama, Mitsuru Saito, Kazuyuki Numakura, Hiroshi Tsuruta, Mingguo Huang, Shigeru Satoh, Tomonori Habuchi
Pages: 678-684
Published online on: 20 December 2013

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Article

Synergistic cell growth inhibition by the combination of amrubicin and Akt-suppressing agents in K-ras mutation-harboring lung adenocarcinoma cells: Implication of EGFR tyrosine kinase inhibitors

Shizuka Ito, Tadashi Igishi, Miyako Takata, Yasuto Ueda, Shingo Matsumoto, Masahiro Kodani, Kenichi Takeda, Hiroki Izumi, Tomohiro Sakamoto, Kosuke Yamaguchi, Haruhiko Makino, Hirokazu Touge, Hiroki Chikumi , Eiji Shimizu
Pages: 685-692
Published online on: 08 January 2014

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Article

Snail-induced epithelial-mesenchymal transition promotes cancer stem cell-like phenotype in head and neck cancer cells

Takashi Masui, Ichiro Ota, Jong-In Yook, Shinji Mikami, Katsunari Yane, Toshiaki Yamanaka, Hiroshi Hosoi
Pages: 693-699
Published online on: 23 December 2013

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Article

The pan-histone deacetylase inhibitor LBH589 (panobinostat) alters the invasive breast cancer cell phenotype

Nicoletta Fortunati, Francesca Marano, Andrea Bandino, Roberto Frairia, Maria Graziella Catalano, Giuseppe Boccuzzi
Pages: 700-708
Published online on: 19 December 2013

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Article

PTEN expression is involved in the invasive properties of HNSCC: A key protein to consider in locoregional recurrence

Jihane Mriouah, Cédric Boura, Myriem Gargouri, François Plénat, Béatrice Faivre
Pages: 709-716
Published online on: 19 December 2013

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Article

Establishment and genetic characterization of ANGM-CSS, a novel, immortal cell line derived from a human glioblastoma multiforme

Angelantonio Notarangelo, Domenico Trombetta, Vincenzo D'Angelo, Paola Parrella, Orazio Palumbo, Clelia Tiziana Storlazzi, Luciana Impera, Lucia Anna Muscarella, Antonella La Torre, Andrea Affuso, Vito Michele Fazio, Massimo Carella, Leopoldo Zelante
Pages: 717-724
Published online on: 23 December 2013

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Article

MicroRNA-301b promotes cell invasiveness through targeting TP63 in pancreatic carcinoma cells

Naotake Funamizu, Curtis Ray Lacy, Sonya T. Parpart, Atsushi Takai, Yukiharu Hiyoshi, Katsuhiko Yanaga
Pages: 725-734
Published online on: 07 January 2014

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Article

The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer cells to PARP inhibition

Qing Xia, Yuchen Cai, Roujun Peng, Guosheng Wu, Yanxia Shi, Wenqi Jiang
Pages: 735-744
Published online on: 31 December 2013

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Article

Effect of Galium verum aqueous extract on growth, motility and gene expression in drug-sensitive and -resistant laryngeal carcinoma cell lines

Marianne Schmidt, Claus-Juergen Scholz, Georgiana-Luminita Gavril, Clemens Otto, Christine Polednik, Jeanette Roller, Rudolf Hagen
Pages: 745-760
Published online on: 19 December 2013

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Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53

Yun-Jeong Choe, Sun-Young Lee, Kyung Won Ko, Seok Joon Shin, Ho-Shik Kim
Pages: 761-768
Published online on: 23 December 2013

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Article

Prostaglandin E2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression

Hai Zhang, Shanyu Cheng, Min Zhang, Xiuping Ma, Li Zhang, Yipin Wang, Rong Rong, Juan Ma, Shukai Xia, Mingzhan Du, Feng Shi, Jie Wang, Qinyi Yang, Xiaoming Bai, Jing Leng
Pages: 769-780
Published online on: 30 December 2013

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Article

S100A6 stimulates proliferation and migration of colorectal carcinoma cells through activation of the MAPK pathways

Liang Duan, Rui Wu, Zhengyu Zou, Haiyan Wang, Liwei Ye, Huan Li, Shimei Yuan, Xueru Li, He Zha, Hui Sun, Yunyuan Zhang, Xian Chen, Lan Zhou
Pages: 781-790
Published online on: 30 December 2013

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Article

Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway

Xiaoyun Shen, Yong Zhang, Yan Feng, Litu Zhang, Jilin Li, Yu-An Xie, Xiaoling Luo
Pages: 791-796
Published online on: 08 January 2014

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Article

Upregulation of the Kank1 gene-induced brain glioma apoptosis and blockade of the cell cycle in G0/G1 phase

Xiaohang Guo, Wenhai Fan, Xinchao Bian, Dihui Ma
Pages: 797-804
Published online on: 08 January 2014

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Article

Cholesterol induces autophagic and apoptotic death in gastric carcinoma cells

Sung-Chul Lim, Keshab Raj Parajuli, Hong-Quan Duong, Jeong Eun Choi, Song Iy Han
Pages: 805-811
Published online on: 07 January 2014

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Article

Metastasis-associated protein 1 promotes tumor invasion by downregulation of E-cadherin

Wenhao Weng, Jiayi Yin, Yue Zhang, Jin Qiu, Xinghe Wang
Pages: 812-818
Published online on: 10 January 2014

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Article

Biodistribution and radiation dosimetry of radioiodinated hypericin as a cancer therapeutic

Marlein Miranda Cona, Michel Koole, Yuanbo Feng, Yewei Liu, Alfons Verbruggen, Raymond Oyen, Yicheng Ni
Pages: 819-829
Published online on: 17 December 2013

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Article Open Access

Apoptotic effect of a novel kefir product, PFT, on multidrug-resistant myeloid leukemia cells via a hole-piercing mechanism

Mamdooh Ghoneum, James Gimzewski
Pages: 830-837
Published online on: 15 January 2014

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Article

Identification of KvLQT1 K+ channels as new regulators of non-small cell lung cancer cell proliferation and migration

Alban Girault, Anik Privé, Nguyen Thu Ngan Trinh, Olivier Bardou, Pasquale Ferraro, Philippe Joubert, Richard Bertrand, Emmanuelle Brochiero
Pages: 838-848
Published online on: 23 December 2013

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Article

Expression of N-acetylglucosaminyltransferase V in gastric cancer correlates with metastasis and prognosis

Binbin Huang, Qiong Wu, Yanli Ge, Junjie Zhang, Longe Sun, Yunyun Zhang, Liu Fu, Juanjuan Fan, Zhirong Wang
Pages: 849-857
Published online on: 08 January 2014

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Article

Curcumin enhances the radiosensitivity in nasopharyngeal carcinoma cells involving the reversal of differentially expressed long non-coding RNAs

Qirui Wang, Haoning Fan, Ying Liu, Zhixin Yin, Hongbing Cai, Jie Liu, Zhiyuan Wang, Meng Shao, Xuegang Sun, Jianxin Diao, Yuanliang Liu, Li Tong, Qin Fan
Pages: 858-864
Published online on: 30 December 2013

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Article

Enhancement of differentiation induction and upregulation of CCAAT/enhancer-binding proteins and PU.1 in NB4 cells treated with combination of ATRA and valproic acid

Noriyoshi Iriyama, Bo Yuan, Yuta Yoshino, Yoshihiro Hatta, Akira Horikoshi, Shin Aizawa, Masami Takei, Jin Takeuchi, Norio Takagi, Hiroo Toyoda
Pages: 865-873
Published online on: 30 December 2013

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Article

Methylated +58CpG site decreases DCN mRNA expression and enhances TGF-β/Smad signaling in NSCLC cells with high metastatic potential

Qian Qian, Xiangguang Shi, Zhe Lei, Lei Zhan, Reng-Yun Liu, Jun Zhao, Binghua Yang, Zeyi Liu, Hong-Tao Zhang
Pages: 874-882
Published online on: 10 January 2014

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Article

Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway

Youn Hee Joung, Yoon Mi Na, Young Bum Yoo, Pramod Darvin, Nipin Sp, Dong Young Kang, Sang Yoon Kim, Hong Sup Kim, Yoon Hee Choi, Hak Kyo Lee, Kyung Do Park, Byung Wook Cho, Heui Soo Kim, Jong Hwan Park, Young Mok Yang
Pages: 883-895
Published online on: 08 January 2014

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Article

The Rho GTPase RhoE is a p53-regulated candidate tumor suppressor in cancer cells

Yajie Zhu, Jitao Zhou, Hongwei Xia, Xiangzheng Chen, Meng Qiu, Juan Huang, Surui Liu, Qiulin Tang, Nan Lang, Zhen Liu, Ming Liu, Yi Zheng, Feng Bi
Pages: 896-904
Published online on: 07 January 2014

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Article

MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells

Sun Hwa Lee, Yong Jung Kang, Bokyung Sung, Dong Hwan Kim, Hyun Sook Lim, Hye Rim Kim, Seong Jin Kim, Jeong-Hyun Yoon, Hyung Ryong Moon, Hae Young Chung, Nam Deuk Kim
Pages: 905-911
Published online on: 10 January 2014

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Article

Combined inhibition of EMMPRIN and epidermal growth factor receptor prevents the growth and migration of head and neck squamous cell carcinoma cells

Shinsuke Suzuki, Kazuo Ishikawa
Pages: 912-917
Published online on: 31 December 2013

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Article

Functional prostate-specific membrane antigen is enriched in exosomes from prostate cancer cells

Tiancheng Liu, Desiree E. Mendes, Clifford E. Berkman
Pages: 918-922
Published online on: 10 January 2014

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Article

Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle

Jaromir Gumulec, Jan Balvan, Marketa Sztalmachova, Martina Raudenska, Veronika Dvorakova, Lucia Knopfova, Hana Polanska, Kristyna Hudcova, Branislav Ruttkay-Nedecky, Petr Babula, Vojtech Adam, Rene Kizek, Marie Stiborova, Michal Masarik
Pages: 923-933
Published online on: 20 December 2013

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Article

Topoisomerase I as a target of erlotinib and gefitinib: Efficacy of combined treatments with camptothecin

Refael Peleg, Dmitri Bobilev, Esther Priel
Pages: 934-942
Published online on: 07 January 2014

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Article

A novel oxiranylchromenone derivative, MHY336, induces apoptosis and cell cycle arrest via a p53- and p21-dependent pathway in HCT116 human colon cancer cells

Sun Hwa Lee, Yong Jung Kang, Dong Hwan Kim, Bokyung Sung, Jin Ah Kang, Pusoon Chun, Jeong-Hyun Yoon, Hyung Ryong Moon, Hyung Sik Kim, Hae Young Chung, Nam Deuk Kim
Pages: 943-949
Published online on: 23 December 2013

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Article

Hypoxia differentially upregulates the expression of embryonic, fetal and adult hemoglobin in human glioblastoma cells

Marwan Emara, A. Robert Turner, Joan Allalunis-Turner
Pages: 950-958
Published online on: 31 December 2013

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Article

Inhibition of NRF2 by PIK-75 augments sensitivity of pancreatic cancer cells to gemcitabine

Hong-Quan Duong, Yong Weon Yi, Hyo Jin Kang, Young Bin Hong, Wenxi Tang, Antai Wang, Yeon-Sun Seong, Insoo Bae
Pages: 959-969
Published online on: 23 December 2013

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Article

Analysis of gene profiles involved in the enhancement of all-trans retinoic acid-induced HL-60 cell differentiation by sesquiterpene lactones identifies asparagine synthetase as a novel target for differentiation-inducing therapy

Ju Han Song, Seung Hyun Kim, Kyung-Min Cho, Seung Yong Hwang, Hyeoung-Joon Kim, Tae Sung Kim
Pages: 970-976
Published online on: 31 December 2013

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Article

ROS-mediated JNK/p38-MAPK activation regulates Bax translocation in Sorafenib-induced apoptosis of EBV-transformed B cells

Ga Bin Park, Yunock Choi, Yeong Seok Kim, Hyun-Kyung Lee, Daejin Kim, Dae Young Hur
Pages: 977-985
Published online on: 09 January 2014

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Article

Effect of a nutrient mixture on matrix metalloproteinase-9 dimers in various human cancer cell lines

M. W. Roomi, T. Kalinovsky, M. Rath, A. Niedzwiecki
Pages: 986-992
Published online on: 30 December 2013

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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