|
1
|
Wei WI and Sham JS: Nasopharyngeal
carcinoma. Lancet. 365:2041–2054. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lo KW, To KF and Huang DP: Focus on
nasopharyngeal carcinoma. Cancer Cell. 5:423–428. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Feng BJ, Huang W, Shugart YY, Lee MK,
Zhang F, Xia JC, Wang HY, Huang TB, Jian SW, Huang P, et al:
Genome-wide scan for familial nasopharyngeal carcinoma reveals
evidence of linkage to chromosome 4. Nat Genet. 31:395–399.
2002.PubMed/NCBI
|
|
4
|
Le QT, Tate D, Koong A, Gibbs IC, Chang
SD, Adler JR, Pinto HA, Terris DJ, Fee WE and Goffinet DR: Improved
local control with stereotactic radiosurgical boost in patients
with nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys.
56:1046–1054. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Shueng PW, Shen BJ, Wu LJ, Liao LJ, Hsiao
CH, Lin YC, Cheng PW, Lo WC, Jen YM and Hsieh CH: Concurrent
image-guided intensity modulated radiotherapy and chemotherapy
following neoadjuvant chemotherapy for locally advanced
nasopharyngeal carcinoma. Radiat Oncol. 6:952011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wang J, Guo LP, Chen LZ, Zeng YX and Lu
SH: Identification of cancer stem cell-like side population cells
in human nasopharyngeal carcinoma cell line. Cancer Res.
67:3716–3724. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yang YP, Chien Y, Chiou GY, Cherng JY,
Wang ML, Lo WL, Chang YL, Huang PI, Chen YW, Shih YH, et al:
Inhibition of cancer stem cell-like properties and reduced
chemoradioresistance of glioblastoma using microRNA145 with
cationic polyurethane-short branch PEI. Biomaterials. 33:1462–1476.
2012. View Article : Google Scholar
|
|
8
|
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q,
Hjelmeland AB, Dewhirst MW, Bigner DD and Rich JN: Glioma stem
cells promote radioresistance by preferential activation of the DNA
damage response. Nature. 444:756–760. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Bonnet D and Dick JE: Human acute myeloid
leukemia is organized as a hierarchy that originates from a
primitive hematopoietic cell. Nat Med. 3:730–737. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Singh SK, Hawkins C, Clarke ID, Squire JA,
Bayani J, Hide T, Henkelman RM, Cusimano MD and Dirks PB:
Identification of human brain tumour initiating cells. Nature.
432:396–401. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ginestier C, Hur MH, Charafe-Jauffret E,
Monville F, Dutcher J, Brown M, Jacquemier J, Viens P, Kleer CG,
Liu S, et al: ALDH1 is a marker of normal and malignant human
mammary stem cells and a predictor of poor clinical outcome. Cell
Stem Cell. 1:555–567. 2007. View Article : Google Scholar
|
|
12
|
Krivtsov AV, Twomey D, Feng Z, Stubbs MC,
Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, et al:
Transformation from committed progenitor to leukaemia stem cell
initiated by MLL-AF9. Nature. 442:818–822. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan
A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, et al: The
epithelial-mesenchymal transition generates cells with properties
of stem cells. Cell. 133:704–715. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Morel AP, Lièvre M, Thomas C, Hinkal G,
Ansieau S and Puisieux A: Generation of breast cancer stem cells
through epithelial-mesenchymal transition. PLoS One. 3:e28882008.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Suvà ML, Riggi N, Stehle JC, Baumer K,
Tercier S, Joseph JM, Suvà D, Clément V, Provero P, Cironi L, et
al: Identification of cancer stem cells in Ewing's sarcoma. Cancer
Res. 69:1776–1781. 2009. View Article : Google Scholar
|
|
16
|
Prince ME, Sivanandan R, Kaczorowski A,
Wolf GT, Kaplan MJ, Dalerba P, Weissman IL, Clarke MF and Ailles
LE: Identification of a subpopulation of cells with cancer stem
cell properties in head and neck squamous cell carcinoma. Proc Natl
Acad Sci USA. 104:973–978. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Su J, Xu XH, Huang Q, Lu MQ, Li DJ, Xue F,
Yi F, Ren JH and Wu YP: Identification of cancer stem-like
CD44+ cells in human nasopharyngeal carcinoma cell line.
Arch Med Res. 42:15–21. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Bareiss PM, Paczulla A, Wang H, Schairer
R, Wiehr S, Kohlhofer U, Rothfuss OC, Fischer A, Perner S, Staebler
A, et al: SOX2 expression associates with stem cell state in human
ovarian carcinoma. Cancer Res. 73:5544–5555. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Koo BS, Lee SH, Kim JM, Huang S, Kim SH,
Rho YS, Bae WJ, Kang HJ, Kim YS, Moon JH, et al: Oct4 is a critical
regulator of stemness in head and neck squamous carcinoma cells.
Oncogene. 34:2317–2324. 2015. View Article : Google Scholar
|
|
20
|
Engelman JA: Targeting PI3K signalling in
cancer: Opportunities, challenges and limitations. Nat Rev Cancer.
9:550–562. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
21
|
Navé BT, Ouwens M, Withers DJ, Alessi DR
and Shepherd PR: Mammalian target of rapamycin is a direct target
for protein kinase B: Identification of a convergence point for
opposing effects of insulin and amino-acid deficiency on protein
translation. Biochem J. 344:427–431. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kolev VN, Wright QG, Vidal CM, Ring JE,
Shapiro IM, Ricono J, Weaver DT, Padval MV, Pachter JA and Xu Q:
PI3K/ mTOR dual inhibitor VS-5584 preferentially targets cancer
stem cells. Cancer Res. 75:446–455. 2015. View Article : Google Scholar
|
|
23
|
Cao Y, Liu X, Lu W, Chen Y, Wu X, Li M,
Wang XA, Zhang F, Jiang L, Zhang Y, et al: Fibronectin promotes
cell proliferation and invasion through mTOR signaling pathway
activation in gallbladder cancer. Cancer Lett. 360:141–150. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Shanmugarantnam KSL: Histological Typing
of Tumors of the Upper Respiratory Tract and Ear. Springer-Verlag;
New York, NY: 1991, View Article : Google Scholar
|
|
25
|
Yang C, Peng J, Jiang W, Zhang Y, Chen X,
Wu X, Zhu Y, Zhang H, Chen J, Wang J, et al: mTOR activation in
immature cells of primary nasopharyngeal carcinoma and anti-tumor
effect of rapamycin in vitro and in vivo. Cancer Lett. 341:186–194.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Bhola P, Banerjee S, Mukherjee J,
Balasubramanium A, Arun V, Karim Z, Burrell K, Croul S, Gutmann DH
and Guha A: Preclinical in vivo evaluation of rapamycin in human
malignant peripheral nerve sheath explant xenograft. Int J Cancer.
126:563–571. 2010. View Article : Google Scholar
|
|
27
|
Turley EA, Noble PW and Bourguignon LY:
Signaling properties of hyaluronan receptors. J Biol Chem.
277:4589–4592. 2002. View Article : Google Scholar
|
|
28
|
Wang SJ and Bourguignon LY: Hyaluronan and
the interaction between CD44 and epidermal growth factor receptor
in oncogenic signaling and chemotherapy resistance in head and neck
cancer. Arch Otolaryngol Head Neck Surg. 132:771–778. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Du L, Wang H, He L, Zhang J, Ni B, Wang X,
Jin H, Cahuzac N, Mehrpour M, Lu Y, et al: CD44 is of functional
importance for colorectal cancer stem cells. Clin Cancer Res.
14:6751–6760. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Patrawala L, Calhoun T,
Schneider-Broussard R, Li H, Bhatia B, Tang S, Reilly JG, Chandra
D, Zhou J, Claypool K, et al: Highly purified CD44+
prostate cancer cells from xenograft human tumors are enriched in
tumorigenic and metastatic progenitor cells. Oncogene.
25:1696–1708. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Wang J, Lu Y, Wang J, Koch AE, Zhang J and
Taichman RS: CXCR6 induces prostate cancer progression by the AKT/
mammalian target of rapamycin signaling pathway. Cancer Res.
68:10367–10376. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Fong YW, Inouye C, Yamaguchi T, Cattoglio
C, Grubisic I and Tjian R: A DNA repair complex functions as an
Oct4/Sox2 coactivator in embryonic stem cells. Cell. 147:120–131.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zhou HY, Katsman Y, Dhaliwal NK, Davidson
S, Macpherson NN, Sakthidevi M, Collura F and Mitchell JA: A Sox2
distal enhancer cluster regulates embryonic stem cell
differentiation potential. Genes Dev. 28:2699–2711. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Gangemi RM, Griffero F, Marubbi D, Perera
M, Capra MC, Malatesta P, Ravetti GL, Zona GL, Daga A and Corte G:
SOX2 silencing in glioblastoma tumor-initiating cells causes stop
of proliferation and loss of tumorigenicity. Stem Cells. 27:40–48.
2009. View Article : Google Scholar
|
|
35
|
Shahryari A, Rafiee MR, Fouani Y, Oliae
NA, Samaei nM, Shafiee M, Semnani S, Vasei M and Mowla SJ: Two
novel splice variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are
coupregulated with SOX2 and OCT4 in esophageal squamous cell
carcinoma. Stem Cells. 32:126–134. 2014. View Article : Google Scholar
|
|
36
|
Yuan TL and Cantley LC: PI3K pathway
alterations in cancer: Variations on a theme. Oncogene.
27:5497–5510. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kalaitzidis D, Sykes SM, Wang Z, Punt N,
Tang Y, Ragu C, Sinha AU, Lane SW, Souza AL, Clish CB, et al: mTOR
complex 1 plays critical roles in hematopoiesis and
Pten-loss-evoked leukemogenesis. Cell Stem Cell. 11:429–439. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Gaur P, Sceusi EL, Samuel S, Xia L, Fan F,
Zhou Y, Lu J, Tozzi F, Lopez-Berestein G, Vivas-Mejia P, et al:
Identification of cancer stem cells in human gastrointestinal
carcinoid and neuroendocrine tumors. Gastroenterology.
141:1728–1737. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Gulhati P, Cai Q, Li J, Liu J, Rychahou
PG, Qiu S, Lee EY, Silva SR, Bowen KA, Gao T, et al: Targeted
inhibition of mammalian target of rapamycin signaling inhibits
tumorigenesis of colorectal cancer. Clin Cancer Res. 15:7207–7216.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Matsumoto K, Arao T, Tanaka K, Kaneda H,
Kudo K, Fujita Y, Tamura D, Aomatsu K, Tamura T, Yamada Y, et al:
mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133
expression in cancer cells. Cancer Res. 69:7160–7164. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Chang WW, Lin RJ, Yu J, Chang WY, Fu CH,
Lai A, Yu JC and Yu AL: The expression and significance of
insulin-like growth factor-1 receptor and its pathway on breast
cancer stemprogenitors. Breast Cancer Res. 15:R392013. View Article : Google Scholar
|
|
42
|
Li J and Zhou BP: Activation of β-catenin
and Akt pathways by Twist are critical for the maintenance of EMT
associated cancer stem cell-like characters. BMC Cancer. 11:492011.
View Article : Google Scholar
|
|
43
|
Egeblad M and Werb Z: New functions for
the matrix metalloproteinases in cancer progression. Nat Rev
Cancer. 2:161–174. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
44
|
Kessenbrock K, Plaks V and Werb Z: Matrix
metalloproteinases: Regulators of the tumor microenvironment. Cell.
141:52–67. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Hotary K, Li XY, Allen E, Stevens SL and
Weiss SJ: A cancer cell metalloprotease triad regulates the
basement membrane transmigration program. Genes Dev. 20:2673–2686.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Bjørnland K, Flatmark K, Pettersen S,
Aaasen AO, Fodstad O and Maelandsmo GM: Matrix metalloproteinases
participate in osteosarcoma invasion. J Surg Res. 127:151–156.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
van Kempen LC and Coussens LM: MMP9
potentiates pulmonary metastasis formation. Cancer Cell. 2:251–252.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Zhang D, Bar-Eli M, Meloche S and Brodt P:
Dual regulation of MMP-2 expression by the type 1 insulin-like
growth factor receptor: The phosphatidylinositol 3-kinase/Akt and
Raf/ ERK pathways transmit opposing signals. J Biol Chem.
279:19683–19690. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Liu SC, Chen C, Chung CH, Wang PC, Wu NL,
Cheng JK, Lai YW, Sun HL, Peng CY, Tang CH, et al: Inhibitory
effects of butein on cancer metastasis and bioenergetic modulation.
J Agric Food Chem. 62:9109–9117. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Chen JS, Wang Q, Fu XH, Huang XH, Chen XL,
Cao LQ, Chen LZ, Tan HX, Li W, Bi J, et al: Involvement of
PI3K/PTEN/ AKT/mTOR pathway in invasion and metastasis in
hepatocellular carcinoma: Association with MMP-9. Hepatol Res.
39:177–186. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Lv C, Kong H, Dong G, Liu L, Tong K, Sun
H, Chen B, Zhang C and Zhou M: Antitumor efficacy of α-solanine
against pancreatic cancer in vitro and in vivo. PLoS One.
9:e878682014. View Article : Google Scholar
|
