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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2015 Volume 47 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

The role of inflammation in progression of breast cancer: Friend or foe? (Review)

Michael D. Allen, Louise J. Jones
Pages: 797-805
Published online on: 08 July 2015

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Review

TFF2, a MUC6-binding lectin stabilizing the gastric mucus barrier and more (Review)

Werner Hoffmann
Pages: 806-816
Published online on: 17 July 2015

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Review

Imaging surveillance programs for women at high breast cancer risk in Europe: Are women from ethnic minority groups adequately included? (Review)

Karen Belkić, Miri Cohen, Brigitte Wilczek, Sonia Andersson, Anne H. Berman, Marcela Márquez, Vladana Vukojević, Miriam Mints
Pages: 817-839
Published online on: 26 June 2015

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Review

Epithelial-mesenchymal transition and drug resistance in breast cancer (Review)

Jing Huang, Hongzhong Li, Guosheng Ren
Pages: 840-848
Published online on: 16 July 2015

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Article Open Access

Vascular endothelial growth factor directly stimulates tumour cell proliferation in non-small cell lung cancer

Aoife M. Devery, Rekha Wadekar, Sivan M. Bokobza, Anika M. Weber, Yanyan Jiang, Anderson J. Ryan
Pages: 849-856
Published online on: 14 July 2015

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Article Open Access

TLR7 and TLR8 expression increases tumor cell proliferation and promotes chemoresistance in human pancreatic cancer

Tanja Grimmig, Niels Matthes, Katharina Hoeland, Sudipta Tripathi, Anil Chandraker, Martin Grimm, Romana Moench, Eva-Maria Moll, Helmut Friess, Igor Tsaur, Roman A. Blaheta, Cristoph T. Germer, Ana Maria Waaga-Gasser, Martin Gasser
Pages: 857-866
Published online on: 02 July 2015

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Article Open Access

Comprehensive screening of genes resistant to an anticancer drug in esophageal squamous cell carcinoma

Mai Tsutsui, Hirofumi Kawakubo, Testsu Hayashida, Kazumasa Fukuda, Rieko Nakamura, Tsunehiro Takahashi, Norihito Wada, Yoshiro Saikawa, Tai Omori, Hiroya Takeuchi, Yuko Kitagawa
Pages: 867-874
Published online on: 16 July 2015

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Article Open Access

A novel in situ permeation system and its utility in cancer tissue ablation

Masami Watanabe
Pages: 875-883
Published online on: 29 June 2015

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Article Open Access

The recurrent chromosomal translocation t(12;18)(q14~15;q12~21) causes the fusion gene HMGA2-SETBP1 and HMGA2 expression in lipoma and osteochondrolipoma

Ioannis Panagopoulos, Ludmila Gorunova, Bodil Bjerkehagen, Ingvild Lobmaier, Sverre Heim
Pages: 884-890
Published online on: 21 July 2015

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Article Open Access

Antitumor effect of YM155, a novel small-molecule survivin suppressant, via mitochondrial apoptosis in human MFH/UPS

Masaya Minoda, Teruya Kawamoto, Takeshi Ueha, Etsuko Kamata, Masayuki Morishita, Risa Harada, Mitsunori Toda, Yasuo Onishi, Hitomi Hara, Masahiro Kurosaka, Toshihiro Akisue
Pages: 891-899
Published online on: 09 July 2015

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Article Open Access

Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma

T. Mahgoub, A. J. Eustace, D. M. Collins, N. Walsh, N. O'Donovan, J. Crown
Pages: 900-908
Published online on: 21 July 2015

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Article Open Access

Downregulation of cancer stem cell properties via mTOR signaling pathway inhibition by rapamycin in nasopharyngeal carcinoma

Chunguang Yang, Yue Zhang, Yu Zhang, Ziheng Zhang, Jianhua Peng, Zhi Li, Liang Han, Quanjie You, Xiaoyu Chen, Xingwang Rao, Yi Zhu, Zhisu Liao
Pages: 909-917
Published online on: 21 July 2015

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Article

Genome-wide transcriptome analysis reveals inactivation of Wnt/β-catenin by 3,3'-diindolylmethane inhibiting proliferation of colon cancer cells

Sun-Hee Leem, Xiu Juan Li, Man Hee Park, Byung Hyun Park, Soo Mi Kim
Pages: 918-926
Published online on: 17 July 2015

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Article

Establishment of a highly metastatic model with a newly isolated lung adenocarcinoma cell line

Yong-Qi Cui, Qin Geng, Tao Yu, Fang-Lin Zhang, He-Chun Lin, Jing Li, Miao-Xin Zhu, Lei Liu, Ming Yao, Ming-Xia Yan
Pages: 927-940
Published online on: 26 June 2015

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Article

Chondromodulin-1 functions as a tumor suppressor in gastric adenocarcinoma

Pengfei Zhang, Ying Wang, Po Xu, Shiyuan Song, Xiaojuan Zhu, Zhenguo Shi, Shegan Gao, Xiaoshan Feng
Pages: 941-950
Published online on: 13 July 2015

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Article

Altered expression of the PLAGL1 (ZAC1/LOT1) gene in colorectal cancer: Correlations to the clinicopathological parameters

Anna E. Kowalczyk, Bartlomiej E. Krazinski, Janusz Godlewski, Jolanta Kiewisz, Przemyslaw Kwiatkowski, Agnieszka Sliwinska-Jewsiewicka, Jacek Kiezun, Piotr M. Wierzbicki, Gabriel Bodek, Marian Sulik, Zbigniew Kmiec
Pages: 951-962
Published online on: 29 June 2015

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Article

The pan-deacetylase inhibitor panobinostat affects angiogenesis in hepatocellular carcinoma models via modulation of CTGF expression

Susanne Gahr, Christian Mayr, Tobias Kiesslich, Romana Illig, Daniel Neureiter, Beate Alinger, Marion Ganslmayer, Till Wissniowski, Pietro Di Fazio, Roberta Montalbano, Joachim H. Ficker, Matthias Ocker, Karl Quint
Pages: 963-970
Published online on: 16 July 2015

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Article

Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells

Jan Hrabeta, Tomas Groh, Mohamed Ashraf Khalil, Jitka Poljakova, Vojtech Adam, Rene Kizek, Jiri Uhlik, Helena Doktorova, Tereza Cerna, Eva Frei, Marie Stiborova, Tomas Eckschlager
Pages: 971-980
Published online on: 29 June 2015

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Article

Riproximin: A type II ribosome inactivating protein with anti-neoplastic potential induces IL24/MDA-7 and GADD genes in colorectal cancer cell lines

Asim Pervaiz, Hassan Adwan, Martin R. Berger
Pages: 981-990
Published online on: 06 July 2015

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Article

A scent of therapy: Synthetic polysulfanes with improved physico-chemical properties induce apoptosis in human cancer cells

Dany Rezk Allah, Lisa Schwind, Imad Abu Asali, Jawad Nasim, Claus Jacob, Claudia Götz, Mathias Montenarh
Pages: 991-1000
Published online on: 20 July 2015

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Article

Downregulation of N-myc downstream regulated gene 1 caused by the methylation of CpG islands of NDRG1 promoter promotes proliferation and invasion of prostate cancer cells

Yalin Li, Pan Pan, Pengfei Qiao, Ranlu Liu
Pages: 1001-1008
Published online on: 16 July 2015

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Article

High-capacity glycolytic and mitochondrial oxidative metabolisms mediate the growth ability of glioblastoma

Jungim Kim, Jeongsu Han, Yunseon Jang, Soo Jeong Kim, Min Joung Lee, Min Jeong Ryu, Gi Ryang Kweon, Jun Young Heo
Pages: 1009-1016
Published online on: 21 July 2015

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Article

Autocrine motility factor promotes epithelial-mesenchymal transition in endometrial cancer via MAPK signaling pathway

Yiran Li, Qi Che, Yiding Bian, Qian Zhou, Feizhou Jiang, Huan Tong, Jieqi Ke, Kai Wang, Xiao-Ping Wan
Pages: 1017-1024
Published online on: 20 July 2015

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Article

Downregulation of miR-95-3p inhibits proliferation, and invasion promoting apoptosis of glioma cells by targeting CELF2

Bo Fan, Bao-Hua Jiao, Feng-Shi Fan, Sheng-Kui Lu, Jian Song, Cheng-Yong Guo, Jian-Kai Yang, Liang Yang
Pages: 1025-1033
Published online on: 10 July 2015

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Article

Cortactin promotes colon cancer progression by regulating ERK pathway

Qing-Feng Ni, Jia-Wei Yu, Fei Qian, Nai-Zhi Sun, Jian-Jia Xiao, Jian-Wei Zhu
Pages: 1034-1042
Published online on: 06 July 2015

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Article

miR-15b promotes epithelial-mesenchymal transition by inhibiting SMURF2 in pancreatic cancer

Wen-Long Zhang, Jian-Hua Zhang, Xi-Zhao Wu, Tao Yan, Wei Lv
Pages: 1043-1053
Published online on: 09 July 2015

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Article

Huaier aqueous extract inhibits cervical cancer cell proliferation via JNK/p38 pathway

Li Yan, Xiaolin Liu, Aijun Yin, Yuyan Wei, Qifeng Yang, Beihua Kong
Pages: 1054-1060
Published online on: 20 July 2015

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Article

Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells

Suchismita Raha, Silvia Yumnam, Gyeong Eun Hong, Ho Jeong Lee, Venu Venkatarame Gowda Saralamma, Hyeon-Soo Park, Jeong Doo Heo, Sang Joon Lee, Eun Hee Kim, Jin-A Kim, Gon Sup Kim
Pages: 1061-1069
Published online on: 20 July 2015

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Article

Enhanced effect of photodynamic therapy in ovarian cancer using a nanoparticle drug delivery system

Zhao Li, Liping Sun, Zaijun Lu, Xuantao Su, Qifeng Yang, Xun Qu, Li Li, Kun Song, Beihua Kong
Pages: 1070-1076
Published online on: 10 July 2015

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Article

Quantitative detection of circulating tumor-derived mitochondrial NADH subunit variants as a potential prognostic biomarker for oral cancer

Katsuhiro Uzawa, Atsushi Kasamatsu, Takao Baba, Yasushi Kimura, Dai Nakashima, Morihiro Higo, Yosuke Sakamoto, Katsunori Ogawara, Masashi Shiiba, Hideki Tanzawa
Pages: 1077-1083
Published online on: 15 July 2015

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Article

Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture

J. M. Wierzbicka, A. Binek, T. Ahrends, J. D. Nowacka, A. Szydłowska, Ł. Turczyk, T. Wąsiewicz, P. M. Wierzbicki, R. Sądej, R. C. Tuckey, A. T. Slominski, J. Chybicki, K. Adrych, Z. Kmieć, M. A. Żmijewski
Pages: 1084-1096
Published online on: 17 July 2015

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Article

Circulating miR-103 and miR-720 as novel serum biomarkers for patients with colorectal cancer

Ryoji Nonaka, Yuichiro Miyake, Taishi Hata, Yoshinori Kagawa, Takeshi Kato, Hideki Osawa, Junichi Nishimura, Masakazu Ikenaga, Kohei Murata, Mamoru Uemura, Daisuke Okuzaki, Ichiro Takemasa, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori
Pages: 1097-1102
Published online on: 26 June 2015

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Article

Bcl-xl and Mcl-1 are the major determinants of the apoptotic response to dual PI3K and MEK blockage

Elina Jokinen, Jussi P. Koivunen
Pages: 1103-1110
Published online on: 02 July 2015

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Article

Tannic acid inhibits the Jak2/STAT3 pathway and induces G1/S arrest and mitochondrial apoptosis in YD-38 gingival cancer cells

Pramod Darvin, Seung Jo Baeg, Youn Hee Joung, Nipin Sp, Dong Young Kang, Hyo Joo Byun, Je Uk Park, Young Mok Yang
Pages: 1111-1120
Published online on: 21 July 2015

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Article

Antisense- and siRNA-mediated inhibition of the anti-apoptotic gene Bcl-xL for chemosensitization of bladder cancer cells

Christiane Rieger, Doreen Huebner, Achim Temme, Manfred P. Wirth, Susanne Fuessel
Pages: 1121-1130
Published online on: 20 July 2015

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Article

New dry powders for inhalation containing temozolomide-based nanomicelles for improved lung cancer therapy

Rémi Rosière, Michel Gelbcke, Véronique Mathieu, Pierre Van Antwerpen, Karim Amighi, Nathalie Wauthoz
Pages: 1131-1142
Published online on: 20 July 2015

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Article

GD2 ganglioside specific antibody treatment downregulates PI3K/Akt/mTOR signaling network in human neuroblastoma cell lines

Małgorzata Durbas, Irena Horwacik, Elżbieta Boratyn, Elżbieta Kamycka, Hanna Rokita
Pages: 1143-1159
Published online on: 02 July 2015

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Article

Preparation and functional characterization of human vascular endothelial growth factor-melittin fusion protein with analysis of the antitumor activity in vitro and in vivo

Dingding Wang, Lili Hu, Manman Su, Ju Wang, Tianmin Xu
Pages: 1160-1168
Published online on: 09 July 2015

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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