1
|
Ritter J and Bielack SS: Osteosarcoma. Ann
Oncol. 21(Suppl 7): vii320–vii325. 2010. View Article : Google Scholar : PubMed/NCBI
|
2
|
Isakoff MS, Bielack SS, Meltzer P and
Gorlick R: Osteosarcoma: Current treatment and a collaborative
pathway to success. J Clin Oncol. 33:3029–3035. 2015. View Article : Google Scholar : PubMed/NCBI
|
3
|
Bishop MW, Janeway KA and Gorlick R:
Future directions in the treatment of osteosarcoma. Curr Opin
Pediatr. 28:26–33. 2016. View Article : Google Scholar :
|
4
|
Jarroux J, Morillon A and Pinskaya M:
History, discovery, and classification of lncRNAs. Adv Exp Med
Biol. 1008:1–46. 2017. View Article : Google Scholar : PubMed/NCBI
|
5
|
Zhu J, Fu H, Wu Y and Zheng X: Function of
lncRNAs and approaches to lncRNA-protein interactions. Sci China
Life Sci. 56:876–885. 2013. View Article : Google Scholar : PubMed/NCBI
|
6
|
Pu FF, Shi DY, Chen T, Liu YX, Zhong BL,
Zhang ZC, Liu WJ, Wu Q, Wang BC, Shao ZW, et al: SP1-induced long
non-coding RNA SNHG6 facilitates the carcinogenesis of
chondrosarcoma through inhibiting KLF6 by recruiting EZH2. Cell
Death Dis. 12:592021. View Article : Google Scholar : PubMed/NCBI
|
7
|
Shi D, Wu F, Mu S, Hu B, Zhong B, Gao F,
Qing X, Liu J, Zhang Z and Shao Z: LncRNA AFAP1-AS1 promotes
tumorigenesis and epithelial-mesenchymal transition of osteosarcoma
through RhoC/ROCK1/p38MAPK/Twist1 signaling pathway. J Exp Clin
Cancer Res. 38:3752019. View Article : Google Scholar : PubMed/NCBI
|
8
|
Vaupel P, Schmidberger H and Mayer A: The
Warburg effect: essential part of metabolic reprogramming and
central contributor to cancer progression. Int J Radiat Biol.
95:912–919. 2019. View Article : Google Scholar : PubMed/NCBI
|
9
|
Dayton TL, Jacks T and Vander Heiden MG:
PKM2, cancer metabolism, and the road ahead. EMBO Rep.
17:1721–1730. 2016. View Article : Google Scholar : PubMed/NCBI
|
10
|
Li YH, Li XF, Liu JT, Wang H, Fan LL, Li J
and Sun GP: PKM2, a potential target for regulating cancer. Gene.
668:48–53. 2018. View Article : Google Scholar : PubMed/NCBI
|
11
|
Wong N, Ojo D, Yan J and Tang D: PKM2
contributes to cancer metabolism. Cancer Lett. 356:184–191. 2015.
View Article : Google Scholar
|
12
|
Zhu S, Guo Y, Zhang X, Liu H, Yin M, Chen
X and Peng C: Pyruvate kinase M2 (PKM2) in cancer and cancer
therapeutics. Cancer Lett. 503:240–248. 2021. View Article : Google Scholar
|
13
|
Liu ZX, Hong L, Fang SQ, Tan GH, Huang PG,
Zeng Z, Xia X and Wang XX: Overexpression of pyruvate kinase M2
predicts a poor prognosis for patients with osteosarcoma. Tumour
Biol. 37:14923–14928. 2016. View Article : Google Scholar : PubMed/NCBI
|
14
|
Shang D, Wu J, Guo L, Xu Y, Liu L and Lu
J: Metformin increases sensitivity of osteosarcoma stem cells to
cisplatin by inhibiting expression of PKM2. Int J Oncol.
50:1848–1856. 2017. View Article : Google Scholar : PubMed/NCBI
|
15
|
Yuan Q, Yu H, Chen J, Song X and Sun L:
Antitumor effect of miR-1294/Pyruvate Kinase M2 signaling cascade
in osteosarcoma cells. Onco Targets Ther. 13:1637–1647. 2020.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Corley M, Burns MC and Yeo GW: How
RNA-binding proteins interact with RNA: Molecules and mechanisms.
Mol Cell. 78:9–29. 2020. View Article : Google Scholar : PubMed/NCBI
|
17
|
Bielli P and Sette C: Analysis of in vivo
Interaction between RNA binding proteins and their RNA targets by
UV cross-linking and immunoprecipitation (CLIP) method. Bio Protoc.
7:e22742017. View Article : Google Scholar :
|
18
|
Chen T, Li Y, Cao W and Liu Y: miR-491-5p
inhibits osteosarcoma cell proliferation by targeting PKM2. Oncol
Lett. 16:6472–6478. 2018.PubMed/NCBI
|
19
|
Chen X, Chen S and Yu D: Protein kinase
function of pyruvate kinase M2 and cancer. Cancer Cell Int.
20:5232020. View Article : Google Scholar : PubMed/NCBI
|
20
|
Wyatt CA, Geoghegan JC and Brinckerhoff
CE: Short hairpin RNA-mediated inhibition of matrix
metalloproteinase-1 in MDA-231 cells: Effects on matrix destruction
and tumor growth. Cancer Res. 65:11101–11108. 2005. View Article : Google Scholar : PubMed/NCBI
|
21
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
22
|
Xia H, Chen D, Wu Q, Wu G, Zhou Y, Zhang Y
and Zhang L: CELF1 preferentially binds to exon-intron boundary and
regulates alternative splicing in HeLa cells. Biochim Biophys Acta
Gene Regul Mech. 1860:911–921. 2017. View Article : Google Scholar : PubMed/NCBI
|
23
|
Xie C, Mao X, Huang J, Ding Y, Wu J, Dong
S, Kong L, Gao G, Li CY and Wei L: KOBAS 2.0: A web server for
annotation and identification of enriched pathways and diseases.
Nucleic Acids Res. 39:W316–W322. 2011. View Article : Google Scholar : PubMed/NCBI
|
24
|
Tang J, Yan T, Bao Y, Shen C, Yu C, Zhu X,
Tian X, Guo F, Liang Q, Liu Q, et al: LncRNA GLCC1 promotes
colorectal carcinogenesis and glucose metabolism by stabilizing
c-Myc. Nat Commun. 10:34992019. View Article : Google Scholar : PubMed/NCBI
|
25
|
Zhao Y, Liu Y, Lin L, Huang Q, He W, Zhang
S, Dong S, Wen Z, Rao J, Liao W and Shi M: The lncRNA MACC1-AS1
promotes gastric cancer cell metabolic plasticity via AMPK/Lin28
mediated mRNA stability of MACC1. Mol Cancer. 17:692018. View Article : Google Scholar : PubMed/NCBI
|
26
|
He L, Zhang H and Zhou X: Weanling
offspring of dams maintained on serine-deficient diet are
vulnerable to oxidative stress. Oxid Med Cell Longev.
2018:80264962018. View Article : Google Scholar : PubMed/NCBI
|
27
|
Soga T, Baran R, Suematsu M, Ueno Y, Ikeda
S, Sakurakawa T, Kakazu Y, Ishikawa T, Robert M, Nishioka T and
Tomita M: Differential metabolomics reveals ophthalmic acid as an
oxidative stress biomarker indicating hepatic glutathione
consumption. J Biol Chem. 281:16768–16776. 2006. View Article : Google Scholar : PubMed/NCBI
|
28
|
Jin C, Zhu X, Wu H, Wang Y and Hu X:
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally
affects glycolysis in cancer cells. J Biol Chem. 295:6425–6446.
2020. View Article : Google Scholar : PubMed/NCBI
|
29
|
Liang Y, Song X, Li Y, Chen B, Zhao W,
Wang L, Zhang H, Liu Y, Han D, Zhang N, et al: LncRNA BCRT1
promotes breast cancer progression by targeting miR-1303/PTBP3
axis. Mol Cancer. 19:852020. View Article : Google Scholar : PubMed/NCBI
|
30
|
Yang XF, Zhou SY, Wang C, Huang W, Li N,
He F and Li FR: Inhibition of LSD1 promotes the differentiation of
human induced pluripotent stem cells into insulin-producing cells.
Stem Cell Res Ther. 11:1852020. View Article : Google Scholar : PubMed/NCBI
|
31
|
Geng F, Cheng X, Wu X, Yoo JY, Cheng C,
Guo JY, Mo X, Ru P, Hurwitz B, Kim SH, et al: Inhibition of SOAT1
suppresses glioblastoma growth via blocking SREBP-1-mediated
lipogenesis. Clin Cancer Res. 22:5337–5348. 2016. View Article : Google Scholar : PubMed/NCBI
|
32
|
Loregger A, Raaben M, Nieuwenhuis J, Tan
JM, Jae LT, van Den Hengel LG, Hendrix S, van Den Berg M, Scheij S,
Song JY, et al: Haploid genetic screens identify SPRING/C12ORF49 as
a determinant of SREBP signaling and cholesterol metabolism. Nat
Commun. 11:11282020. View Article : Google Scholar : PubMed/NCBI
|
33
|
World Medical Association and American
Physiological Society: Guiding principles for research involving
animals and human beings. Am J Physiol Regul Integr Comp Physiol.
283:R281–R283. 2002. View Article : Google Scholar : PubMed/NCBI
|
34
|
Pu F, Chen F, Zhang Z, Qing X, Lin H, Zhao
L, Xia P and Shao Z: TIM-3 expression and its association with
overall survival in primary osteosarcoma. Oncol Lett. 18:5294–5300.
2019.PubMed/NCBI
|
35
|
Tang T, Guo C, Xia T, Zhang R, Zen K, Pan
Y and Jin L: LncCCAT1 promotes breast cancer stem cell function
through activating WNT/β-catenin signaling. Theranostics.
9:7384–7402. 2019. View Article : Google Scholar :
|
36
|
Yang W, Zheng Y, Xia Y, Ji H, Chen X, Guo
F, Lyssiotis CA, Aldape K, Cantley LC and Lu Z: ERK1/2-dependent
phosphorylation and nuclear translocation of PKM2 promotes the
warburg effect. Nat Cell Biol. 14:1295–1304. 2012. View Article : Google Scholar : PubMed/NCBI
|
37
|
Iansante V, Choy PM, Fung SW, Liu Y, Chai
JG, Dyson J, Del Rio A, D'Santos C, Williams R, Chokshi S, et al:
PARP14 promotes the warburg effect in hepatocellular carcinoma by
inhibiting JNK1-dependent PKM2 phosphorylation and activation. Nat
Commun. 6:78822015. View Article : Google Scholar : PubMed/NCBI
|
38
|
Liang J, Cao R, Zhang Y, Xia Y, Zheng Y,
Li X, Wang L, Yang W and Lu Z: PKM2 dephosphorylation by Cdc25A
promotes the warburg effect and tumorigenesis. Nat Commun.
7:124312016. View Article : Google Scholar : PubMed/NCBI
|
39
|
Herjan T, Hong L, Bubenik J, Bulek K, Qian
W, Liu C, Li X, Chen X, Yang H, Ouyang S, et al:
IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to
mediate IL-17 inflammatory signaling. Nat Immunol. 19:354–365.
2018. View Article : Google Scholar : PubMed/NCBI
|
40
|
Abedini P, Fattahi A, Agah S, Talebi A,
Beygi AH, Amini SM, Mirzaei A and Akbari A: Expression analysis of
circulating plasma long noncoding RNAs in colorectal cancer: The
relevance of lncRNAs ATB and CCAT1 as potential clinical hallmarks.
J Cell Physiol. 234:22028–22033. 2019. View Article : Google Scholar : PubMed/NCBI
|
41
|
Yang W, Xia Y, Ji H, Zheng Y, Liang J,
Huang W, Gao X, Aldape K and Lu Z: Nuclear PKM2 regulates β-catenin
transactivation upon EGFR activation. Nature. 480:118–122. 2011.
View Article : Google Scholar : PubMed/NCBI
|
42
|
Zhu H, Luo H and Zhu X, Hu X, Zheng L and
Zhu X: Pyruvate kinase M2 (PKM2) expression correlates with
prognosis in solid cancers: A meta-analysis. Oncotarget.
8:1628–1640. 2017. View Article : Google Scholar :
|
43
|
Wiese EK and Hitosugi T: Tyrosine kinase
signaling in cancer metabolism: PKM2 paradox in the warburg effect.
Front Cell Dev Biol. 6:792018. View Article : Google Scholar : PubMed/NCBI
|
44
|
Alquraishi M, Puckett DL, Alani DS,
Humidat AS, Frankel VD, Donohoe DR, Whelan J and Bettaieb A:
Pyruvate kinase M2: A simple molecule with complex functions. Free
Radic Biol Med. 143:176–192. 2019. View Article : Google Scholar : PubMed/NCBI
|
45
|
Israelsen WJ and Vander Heiden MG:
Pyruvate kinase: Function, regulation and role in cancer. Semin
Cell Dev Biol. 43:43–51. 2015. View Article : Google Scholar : PubMed/NCBI
|
46
|
Luo W and Semenza GL: Emerging roles of
PKM2 in cell metabolism and cancer progression. Trends Endocrinol
Metab. 23:560–566. 2012. View Article : Google Scholar : PubMed/NCBI
|
47
|
Hombach S and Kretz M: Non-coding RNAs:
Classification, biology and functioning. Adv Exp Med Biol.
937:3–17. 2016. View Article : Google Scholar : PubMed/NCBI
|
48
|
Li Q, Uemura Y and Kawahara Y:
Cross-linking and immunoprecipitation of nuclear RNA-binding
proteins. Methods Mol Biol. 1262:247–263. 2015. View Article : Google Scholar : PubMed/NCBI
|
49
|
Chen F, Wang Q, Yu X, Yang N, Wang Y, Zeng
Y, Zheng Z, Zhou F and Zhou Y: MCPIP1-mediated NFIC alternative
splicing inhibits proliferation of triple-negative breast cancer
via cyclin D1-Rb-E2F1 axis. Cell Death Dis. 12:3702021. View Article : Google Scholar : PubMed/NCBI
|
50
|
Li W, Zhang Z, Liu X, Cheng X, Zhang Y,
Han X, Zhang Y, Liu S, Yang J, Xu B, et al: The FOXN3-NEAT1-SIN3A
repressor complex promotes progression of hormonally responsive
breast cancer. J Clin Invest. 127:3421–3440. 2017. View Article : Google Scholar : PubMed/NCBI
|
51
|
Bhan A, Soleimani M and Mandal SS: Long
noncoding RNA and cancer: A new paradigm. Cancer Res. 77:3965–3981.
2017. View Article : Google Scholar : PubMed/NCBI
|
52
|
Peng WX, Koirala P and Mo YY:
LncRNA-mediated regulation of cell signaling in cancer. Oncogene.
36:5661–5667. 2017. View Article : Google Scholar : PubMed/NCBI
|
53
|
Sanchez Calle A, Kawamura Y, Yamamoto Y,
Takeshita F and Ochiya T: Emerging roles of long non-coding RNA in
cancer. Cancer Sci. 109:2093–2100. 2018. View Article : Google Scholar : PubMed/NCBI
|
54
|
Tao T, Wu S, Sun Z, Ma W, Zhou S, Deng J,
Su Q, Peng M, Xu G and Yang X: The molecular mechanisms of
LncRNA-correlated PKM2 in cancer metabolism. Biosci Rep.
39:BSR201924532019. View Article : Google Scholar : PubMed/NCBI
|
55
|
Puckett DL, Alquraishi M, Chowanadisai W
and Bettaieb A: The role of PKM2 in metabolic reprogramming:
Insights into the regulatory roles of non-coding RNAs. Int J Mol
Sci. 22:11712021. View Article : Google Scholar : PubMed/NCBI
|
56
|
Wang C, Li Y, Yan S, Wang H, Shao X, Xiao
M, Yang B, Qin G, Kong R, Chen R and Zhang N: Interactome analysis
reveals that lncRNA HULC promotes aerobic glycolysis through LDHA
and PKM2. Nat Commun. 11:31622020. View Article : Google Scholar : PubMed/NCBI
|
57
|
Panasyuk G, Espeillac C, Chauvin C,
Pradelli LA, Horie Y, Suzuki A, Annicotte JS, Fajas L, Foretz M,
Verdeguer F, et al: PPAR gamma contributes to PKM2 and HK2
expression in fatty liver. Nat Commun. 3:6722012. View Article : Google Scholar
|
58
|
Zhao X, Zhao L, Yang H, Li J, Min X, Yang
F, Liu J and Huang G: Pyruvate kinase M2 interacts with nuclear
sterol regulatory element-binding protein 1a and thereby activates
lipogenesis and cell proliferation in hepatocellular carcinoma. J
Biol Chem. 293:6623–6634. 2018. View Article : Google Scholar : PubMed/NCBI
|
59
|
Eberle D, Hegarty B, Bossard P, Ferré P
and Foufelle F: SREBP transcription factors: Master regulators of
lipid homeostasis. Biochimie. 86:839–848. 2004. View Article : Google Scholar : PubMed/NCBI
|
60
|
Horton JD, Goldstein JL and Brown MS:
SREBPs: Activators of the complete program of cholesterol and fatty
acid synthesis in the liver. J Clin Invest. 109:1125–1131. 2002.
View Article : Google Scholar : PubMed/NCBI
|
61
|
Zeng L, Lu M, Mori K, Luo S, Lee AS, Zhu Y
and Shyy JY: ATF6 modulates SREBP2-mediated lipogenesis. EMBO J.
23:950–958. 2004. View Article : Google Scholar : PubMed/NCBI
|