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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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October-2021 Volume 15 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Case Report Open Access

IgD multiple myeloma with central nervous system involvement: A case report and literature review

  • Authors:
    • Yi Chen
    • Yanyan Qiu
    • Haiying Fu
    • Jing Li
    • Lushan Chen
    • Siqin Liao
    • Tingbo Liu
  • View Affiliations / Copyright

    Affiliations: Fujian Provincial Key Laboratory on Haematology, Fujian Medical University Union Hospital, Fujian Institute of Haematology, Fuzhou, Fujian 350001, P.R. China
    Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 198
    |
    Published online on: August 4, 2021
       https://doi.org/10.3892/mco.2021.2360
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Abstract

Central nervous system (CNS) involvement is a rare manifestation of multiple myeloma (MM) and the optimal management strategies have yet to be determined. The aim of the present study was to describe the case of a 47‑year‑old male patient with immunoglobulin D‑λ MM who presented with multiple extramedullary infiltrations at diagnosis. This patient achieved stringent complete response after 9 cycles of treatment with bortezomib, lenalidomide and dexamethasone, and then received lenalidomide as maintenance therapy. CNS involvement and extramedullary relapse developed 3 months after the last chemotherapy cycle. Despite receiving a second‑line treatment protocol, the patient succumbed to the disease within 1 month after recurrence. The characteristics and treatment options for CNS MM are discussed in this case report.
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Copy and paste a formatted citation
Spandidos Publications style
Chen Y, Qiu Y, Fu H, Li J, Chen L, Liao S and Liu T: IgD multiple myeloma with central nervous system involvement: A case report and literature review. Mol Clin Oncol 15: 198, 2021.
APA
Chen, Y., Qiu, Y., Fu, H., Li, J., Chen, L., Liao, S., & Liu, T. (2021). IgD multiple myeloma with central nervous system involvement: A case report and literature review. Molecular and Clinical Oncology, 15, 198. https://doi.org/10.3892/mco.2021.2360
MLA
Chen, Y., Qiu, Y., Fu, H., Li, J., Chen, L., Liao, S., Liu, T."IgD multiple myeloma with central nervous system involvement: A case report and literature review". Molecular and Clinical Oncology 15.4 (2021): 198.
Chicago
Chen, Y., Qiu, Y., Fu, H., Li, J., Chen, L., Liao, S., Liu, T."IgD multiple myeloma with central nervous system involvement: A case report and literature review". Molecular and Clinical Oncology 15, no. 4 (2021): 198. https://doi.org/10.3892/mco.2021.2360
Copy and paste a formatted citation
x
Spandidos Publications style
Chen Y, Qiu Y, Fu H, Li J, Chen L, Liao S and Liu T: IgD multiple myeloma with central nervous system involvement: A case report and literature review. Mol Clin Oncol 15: 198, 2021.
APA
Chen, Y., Qiu, Y., Fu, H., Li, J., Chen, L., Liao, S., & Liu, T. (2021). IgD multiple myeloma with central nervous system involvement: A case report and literature review. Molecular and Clinical Oncology, 15, 198. https://doi.org/10.3892/mco.2021.2360
MLA
Chen, Y., Qiu, Y., Fu, H., Li, J., Chen, L., Liao, S., Liu, T."IgD multiple myeloma with central nervous system involvement: A case report and literature review". Molecular and Clinical Oncology 15.4 (2021): 198.
Chicago
Chen, Y., Qiu, Y., Fu, H., Li, J., Chen, L., Liao, S., Liu, T."IgD multiple myeloma with central nervous system involvement: A case report and literature review". Molecular and Clinical Oncology 15, no. 4 (2021): 198. https://doi.org/10.3892/mco.2021.2360
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