Open Access

ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review

  • Authors:
    • Semaa A. Shaban
    • Aya M. Al‑Rahim
    • Ahmed Abduljabbar Suleiman
  • View Affiliations

  • Published online on: February 21, 2022     https://doi.org/10.3892/mco.2022.2519
  • Article Number: 86
  • Copyright: © Shaban et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cancer is a major health issue worldwide. cfDNA integrity has been reported as a potential diagnostic molecular marker for different types of cancer, identifying the importance of liquid biopsy. The aim of this review was to evaluate the prognostic and diagnostic performance of Arthrobacter luteus (ALU) repeat in tumor. Following a thorough review of the literature published from January, 2000 to September 2021, 36 studies were included. All of the study descriptions were analyzed. According to several studies, there were increased concentrations of ALU repetitive elements in cancer patients, while these concentrations were decreased in control, benign, different cancer stage, and other diseases. The total ALU (115 and 247) sequence levels are potential biomarkers for the purpose of investigations and cancer prognosis.
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April-2022
Volume 16 Issue 4

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Spandidos Publications style
Shaban SA, Al‑Rahim AM and Suleiman AA: ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review. Mol Clin Oncol 16: 86, 2022
APA
Shaban, S.A., Al‑Rahim, A.M., & Suleiman, A.A. (2022). ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review. Molecular and Clinical Oncology, 16, 86. https://doi.org/10.3892/mco.2022.2519
MLA
Shaban, S. A., Al‑Rahim, A. M., Suleiman, A. A."ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review". Molecular and Clinical Oncology 16.4 (2022): 86.
Chicago
Shaban, S. A., Al‑Rahim, A. M., Suleiman, A. A."ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review". Molecular and Clinical Oncology 16, no. 4 (2022): 86. https://doi.org/10.3892/mco.2022.2519