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ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review

  • Authors:
    • Semaa A. Shaban
    • Aya M. Al‑Rahim
    • Ahmed Abduljabbar Suleiman
  • View Affiliations / Copyright

    Affiliations: Department of Biology, College of Sciences, Tikrit University, Tikrit, Saladin 34001, Iraq, Department of Molecular and Medical Biotechnology, College of Biotechnology, Al‑Nahrain University, Baghdad 64074, Iraq, Department of Biotechnology, Science College, University of Anbar, Ramadi, Anbar 46006, Iraq
    Copyright: © Shaban et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 86
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    Published online on: February 21, 2022
       https://doi.org/10.3892/mco.2022.2519
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Abstract

Cancer is a major health issue worldwide. cfDNA integrity has been reported as a potential diagnostic molecular marker for different types of cancer, identifying the importance of liquid biopsy. The aim of this review was to evaluate the prognostic and diagnostic performance of Arthrobacter luteus (ALU) repeat in tumor. Following a thorough review of the literature published from January, 2000 to September 2021, 36 studies were included. All of the study descriptions were analyzed. According to several studies, there were increased concentrations of ALU repetitive elements in cancer patients, while these concentrations were decreased in control, benign, different cancer stage, and other diseases. The total ALU (115 and 247) sequence levels are potential biomarkers for the purpose of investigations and cancer prognosis.
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Spandidos Publications style
Shaban SA, Al‑Rahim AM and Suleiman AA: ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review. Mol Clin Oncol 16: 86, 2022.
APA
Shaban, S.A., Al‑Rahim, A.M., & Suleiman, A.A. (2022). ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review. Molecular and Clinical Oncology, 16, 86. https://doi.org/10.3892/mco.2022.2519
MLA
Shaban, S. A., Al‑Rahim, A. M., Suleiman, A. A."ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review". Molecular and Clinical Oncology 16.4 (2022): 86.
Chicago
Shaban, S. A., Al‑Rahim, A. M., Suleiman, A. A."ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review". Molecular and Clinical Oncology 16, no. 4 (2022): 86. https://doi.org/10.3892/mco.2022.2519
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Spandidos Publications style
Shaban SA, Al‑Rahim AM and Suleiman AA: ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review. Mol Clin Oncol 16: 86, 2022.
APA
Shaban, S.A., Al‑Rahim, A.M., & Suleiman, A.A. (2022). ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review. Molecular and Clinical Oncology, 16, 86. https://doi.org/10.3892/mco.2022.2519
MLA
Shaban, S. A., Al‑Rahim, A. M., Suleiman, A. A."ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review". Molecular and Clinical Oncology 16.4 (2022): 86.
Chicago
Shaban, S. A., Al‑Rahim, A. M., Suleiman, A. A."ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review". Molecular and Clinical Oncology 16, no. 4 (2022): 86. https://doi.org/10.3892/mco.2022.2519
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