|
1
|
Kose EA, Bakar B, Ayva SK, Kilinc K and
Apan A: Neuroprotective effects of racemic ketamine and
(S)-ketamine on spinal cord injury in rat. Injury. 43:1124–1130.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bulsara KR, Iskandar BJ, Villavicencio AT
and Skene JH: A new millenium for spinal cord regeneration:
growth-associated genes. Spine (Phila Pa 1976). 27:1946–1949. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Szpara ML, Vranizan K, Tai YC, Goodman CS,
Speed TP and Ngai J: Analysis of gene expression during neurite
outgrowth and regeneration. BMC Neurosci. 8:1002007. View Article : Google Scholar
|
|
4
|
Busch SA and Silver J: The role of
extracellular matrix in CNS regeneration. Curr Opin Neurobiol.
17:120–127. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Liu BP, Cafferty WB, Budel SO and
Strittmatter SM: Extracellular regulators of axonal growth in the
adult central nervous system. Philos Trans R Soc Lond B Biol Sci.
361:1593–1610. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
McGee AW and Strittmatter SM: The Nogo-66
receptor: focusing myelin inhibition of axon regeneration. Trends
Neurosci. 26:193–198. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
McKerracher L, David S, Jackson DL, et al:
David S, Jackson DL, Kottis V, Dunn RJ and Braun PE: Identification
of myelin-associated glycoprotein as a major myelin-derived
inhibitor of neurite growth. Neuron. 13:805–811. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Mukhopadhyay G, Doherty P, Walsh FS,
Crocker PR and Filbin MT: A novel role for myelin-associated
glycoprotein as an inhibitor of axonal regeneration. Neuron.
13:757–767. 1994. View Article : Google Scholar
|
|
9
|
Chen MS, Huber AB, van der Haar ME, Frank
M, Schnell L, Spillmann AA, Christ F and Schwab ME: Nogo-A is a
myelin-associated neurite outgrowth inhibitor and an antigen for
monoclonal antibody IN-1. Nature. 403:434–439. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
GrandPré T, Nakamura F, Vartanian T and
Strittmatter SM: Identification of the Nogo inhibitor of axon
regeneration as a Reticulon protein. Nature. 403:439–444.
2000.PubMed/NCBI
|
|
11
|
Hata K, Hata K, Fujitani M, Yasuda Y, Doya
H, Saito T, Yamagishi S, Mueller BK and Yamashita T: RGMa
inhibition promotes axonal growth and recovery after spinal cord
injury. J Cell Biol. 173:47–58. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Moreau-Fauvarque C, Kumanogoh A, Camand E,
Jaillard C, Barbin G, Boquet I, Love C, Jones EY, Kikutani H,
Lubetzki C, Dusart I and Chédotal A: The transmembrane semaphorin
Sema4D/CD100, an inhibitor of axonal growth, is expressed on
oligodendrocytes and upregulated after CNS lesion. J Neurosci.
23:9229–9239. 2003.PubMed/NCBI
|
|
13
|
Löw K, Culbertson M, Bradke F,
Tessier-Lavigne M and Tuszynski MH: Netrin-1 is a novel
myelin-associated inhibitor to axon growth. J Neurosci.
28:1099–1108. 2008.PubMed/NCBI
|
|
14
|
Irizarry-Ramírez M, Willson CA,
Cruz-Orengo L, Figueroa J, et al: Upregulation of EphA3 receptor
after spinal cord injury. J Neurotrauma. 22:929–935.
2005.PubMed/NCBI
|
|
15
|
Klein R: Bidirectional modulation of
synaptic functions by Eph/ephrin signaling. Nat Neurosci. 12:15–20.
2009. View
Article : Google Scholar : PubMed/NCBI
|
|
16
|
Aoto J and Chen L: Bidirectional
ephrin/Eph signaling in synaptic functions. Brain Res. 1184:72–80.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kullander K, Croll SD, Zimmer M, Pan L,
McClain J, Hughes V, Zabski S, DeChiara TM, Klein R, Yancopoulos GD
and Gale W: Ephrin-B3 is the midline barrier that prevents
corticospinal tract axons from recrossing, allowing for unilateral
motor control. Genes Dev. 15:877–888
|
|
18
|
Asante CO, Chu A, Fisher M, Benson L, Beg
A, Scheiffele P and Martin J: Cortical control of adaptive
locomotion in wild-type mice and mutant mice lacking the ephrin-Eph
effector protein alpha2-chimaerin. J Neurophysiol. 104:3189–3202.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Liu X, Hawkes E, Ishimaru T, Tran T and
Sretavan DW: EphB3: an endogenous mediator of adult axonal
plasticity and regrowth after CNS injury. J Neurosci. 26:3087–3101.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Leighton PA, Mitchell KJ, Goodrich LV, Lu
X, Pinson K, Scherz P, Skarnes WC and Tessier-Lavigne M: Defining
brain wiring patterns and mechanisms through gene trapping in mice.
Nature. 410:174–179. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
21
|
Yokoyama N, Romero MI, Cowan CA, Galvan P,
Helmbacher F, Charnay P, Parada LF and Henkemeyer M: Forward
signaling mediated by ephrin-B3 prevents contralateral
corticospinal axons from recrossing the spinal cord midline.
Neuron. 29:85–97. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Duffy P, Wang X, Siegel CS, Tu N,
Henkemeyer M, Cafferty WB and Strittmatter SM: Myelin-derived
ephrinB3 restricts axonal regeneration and recovery after adult CNS
injury. Proc Natl Acad Sci USA. 109:5063–5068. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Elbashir SM, Harborth J, Weber K and
Tuschl T: Analysis of gene function in somatic mammalian cells
using small interfering RNAs. Methods. 26:199–213. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Coleman JE, Huentelman MJ, Kasparov S,
Metcalfe BL, et al: Efficient large-scale production and
concentration of HIV-1-based lentiviral vectors for use in vivo.
Physiol Genomics. 12:221–228. 2002.PubMed/NCBI
|
|
25
|
Déglon N, Tseng JL, Bensadoun JC, Zurn AD,
Arsenijevic Y, Pereira de Almeida L, Zufferey R, Trono D and
Aebischer P: Self-inactivating lentiviral vectors with enhanced
transgene expression as potential gene transfer system in
Parkinson’s disease. Hum Gene Ther. 11:179–190. 2000.PubMed/NCBI
|
|
26
|
Basso DM, Beattie MS and Bresnahan JC: A
sensitive and reliable locomotor rating scale for open field
testing in rats. J Neurotrauma. 12:1–21. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Goldstein LB: Effects of bilateral and
unilateral locus coeruleus lesions on beam-walking recovery after
subsequent unilateral sensorimotor cortex suction-ablation in the
rat. Restor Neurol Neurosci. 11:55–63. 1997.
|
|
28
|
Silver J and Miller JH: Regeneration
beyond the glial scar. Nat Rev Neurosci. 5:146–156. 2004.
View Article : Google Scholar
|
|
29
|
Genander M and Frisén J: Ephrins and Eph
receptors in stem cells and cancer. Curr Opin Cell Biol.
22:611–666. 2010.PubMed/NCBI
|
|
30
|
Carmona MA, Murai KK, Wang L, Roberts AJ
and Pasquale EB: Glial ephrin-A3 regulates mhippocampal dendritic
spine morphology and glutamate transport. Proc Natl Acad Sci USA.
106:12524–12529. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Goldshmit Y, Galea MP, Wise G, Bartlett PF
and Turnley AM: Axonal regeneration and lack of astrocytic gliosis
in EphA4-deficient mice. J Neurosci. 24:10064–10073. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Benson MD, Romero MI, Lush ME, Lu QR,
Henkemeyer M and Parada LF: Ephrin-B3 is a myelin-based inhibitor
of neurite outgrowth. Proc Natl Acad Sci USA. 102:10694–10699.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Dorn G, Patel S, Wotherspoon G, et al:
siRNA relieves chronic neuropathic pain. Nucleic Acids Res.
32:e492002. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Xia H, Mao Q, Eliason S, Harper SQ,
Martins IH, Orr HT, Paulson HL, Yang L, Kotin RM and Davidson BL:
RNAi suppresses polyglutamine-induced neurodegeneration in a model
of spinocerebellar ataxia. Nat Med. 10:816–820. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Harper SQ, Staber PD, He X, Eliason SL,
Martins IH, Mao Q, Yang L, Kotin RM, Paulson HL and Davidson BL:
RNA interference improves motor and neuropathological abnormalities
in a Huntington’s disease mouse model. Proc Natl Acad Sci USA.
102:5820–5825. 2005.
|
|
36
|
Ralph GS, Radcliffe PA, Day DM, Carthy JM,
Leroux MA, Lee DC, Wong LF, Bilsland LG, Greensmith L, Kingsman SM,
Mitrophanous KA, Mazarakis ND and Azzouz M: Silencing mutant SOD1
using RNAi protects against neurodegeneration and extends survival
in an ALS model. Nat Med. 11:429–433. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Raoul C, Abbas-Terki T, Bensadoun JC,
Guillot S, Haase G, Szulc J, Henderson CE and Aebischer P:
Lentiviral-mediated silencing of SOD1 through RNA interference
retards disease onset and progression in a mouse model of ALS. Nat
Med. 11:423–428. 2005.PubMed/NCBI
|
|
38
|
Adriaansen J, Vervoordeldonk MJ and Tak
PP: Gene therapy as a therapeutic approach for the treatment of
rheumatoid arthritis: innovative vectors and therapeutic genes.
Rheumatology (Oxford). 45:656–668. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Manjunath N, Wu H, Subramanya S and
Shankar P: Lentiviral delivery of short hairpin RNAs. Adv Drug
Deliv Rev. 61:732–745. 2009. View Article : Google Scholar : PubMed/NCBI
|
