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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2014 Volume 9 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis (Review)

Hiroshi Kobayashi, Shogo Imanaka, Haruki Nakamura, Ayumi Tsuji
Pages: 1483-1505
Published online on: 14 March 2014

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Review

Direct thrombin inhibitors: Patents 2002-2012 (Review)

Yi Kong, Hao Chen, Yong-Qing Wang, Ling Meng, Ji-Fu Wei
Pages: 1506-1514
Published online on: 06 March 2014

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Review Open Access

Limb-girdle muscular dystrophies: Where next after six decades from the first proposal (Review)

Omar A. Mahmood, Xin Mei Jiang
Pages: 1515-1532
Published online on: 13 March 2014

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Review

Monoamine oxidase inhibitors: Promising therapeutic agents for Alzheimer's disease (Review)

Zhiyou Cai
Pages: 1533-1541
Published online on: 11 March 2014

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Article

Molecular targets and mechanism of action of dexmedetomidine in treatment of ischemia/reperfusion injury

Ye Cai, Hui Xu, Jia Yan, Lei Zhang, Yi Lu
Pages: 1542-1550
Published online on: 10 March 2014

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Article Open Access

A pivotal role of the vascular endothelial growth factor signaling pathway in the formation of venous hypertension-induced dural arteriovenous fistulas

Qiang Li, Qi Zhang, Qing-Hai Huang, Yi-Bin Fang, Zhao-Long Zhang, Yi Xu, Jian-Min Liu
Pages: 1551-1558
Published online on: 11 March 2014

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Article Open Access

Prognostic performance of a series of model for end‑stage liver disease and respective Δ scores in patients with hepatitis B acute-on-chronic liver failure

Yun-Hao Xun, Jun-Ping Shi, Chun-Qing Li, Dan Li, Wei-Zhen Shi, Qing-Chun Pan, Jian-Chun Guo, Guo-Qing Zang
Pages: 1559-1568
Published online on: 25 February 2014

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Article Open Access

Anti-inflammatory and anti-proliferative effect of herbal medicines (APR) in RAW264.7 cells

Han-Seok Choi, Hye Sook Seo, Soon Re Kim, Youn Kyung Choi, Yong-Cheol Shin, Seong-Gyu Ko
Pages: 1569-1574
Published online on: 10 March 2014

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Article Open Access

The SDF-1/CXCR4 axis regulates migration of transplanted bone marrow mesenchymal stem cells towards the pancreas in rats with acute pancreatitis

Jian Gong, Hong-Bo Meng, Jie Hua, Zhen-Shun Song, Zhi‑Gang He, Bo Zhou, Ming-Ping Qian
Pages: 1575-1582
Published online on: 14 March 2014

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Article

Mesenchymal stem cell-based developmental endothelial locus-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice

Yun-Feng Zhao, Wei Xiong, Xue-Ling Wu
Pages: 1583-1589
Published online on: 26 February 2014

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Article

Apelin-13 stimulates angiogenesis by promoting cross‑talk between AMP-activated protein kinase and Akt signaling in myocardial microvascular endothelial cells

Xiaoman Yang, Wei Zhu, Pu Zhang, Kankai Chen, Lijie Zhao, Jingbo Li, Meng Wei, Mingya Liu
Pages: 1590-1596
Published online on: 25 February 2014

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Article Open Access

Pilot genome-wide study of tandem 3' UTRs in esophageal cancer using high-throughput sequencing

Mingzhong Sun, Huixiang Ju, Zhongwei Zhou, Rong Zhu
Pages: 1597-1605
Published online on: 04 March 2014

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Article

c-Jun transactivates Puma gene expression to promote osteoarthritis

Huading Lu, Gang Hou, Yongkai Zhang, Yuhu Dai, Huiqing Zhao
Pages: 1606-1612
Published online on: 24 February 2014

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Article Open Access

KLF8 knockdown suppresses proliferation and invasion in human osteosarcoma cells

Feng Lin, Zan Shen, Li‑Na Tang, Shui‑Er Zheng, Yuan‑Jue Sun, Da‑Liu Min, Yang Yao
Pages: 1613-1617
Published online on: 07 March 2014

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Article Open Access

Phosphodiesterase 3A rs7134375 single nucleotide polymorphism and serum lipid levels

Wei Wang, Rui‑Xing Yin, Dong‑Feng Wu, Lynn Htet Htet Aung, Ping Huang, Xiao‑Na Zeng, Ke‑Ke Huang, Quan‑Zhen Lin, Jian Wu, Tao Guo
Pages: 1618-1628
Published online on: 04 March 2014

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Article

Impaired hematopoiesis and delayed thrombopoietic recovery following sublethal irradiation in SRC‑3 knockout mice

J. Jin, Y. Wang, J. Wang, Y. Xu, S. L. Chen, J. P. Wang, Y. P. Su
Pages: 1629-1633
Published online on: 12 March 2014

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Article Open Access

Retinol binding protein 4 promotes hyperinsulinism‑induced proliferation of rat aortic smooth muscle cells

Fei Li, Ke Xia, Md Sayed Ali Sheikh, Jinfang Cheng, Chuanchang Li, Tianlun Yang
Pages: 1634-1640
Published online on: 07 March 2014

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Article Open Access

F‑actin cytoskeleton reorganization is associated with hepatic stellate cell activation

Xiaodong Cui, Xiaoyun Zhang, Qingling Yin, Aixia Meng, Shaojuan Su, Xu Jing, Hong Li, Xiumei Guan, Xin Li, Shunmei Liu, Min Cheng
Pages: 1641-1647
Published online on: 11 March 2014

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Article Open Access

Werner syndrome protein positively regulates XRCC4-like factor transcription

Dongyun Liu, Xiaoli Deng, Chongzhen Yuan, Lin Chen, Yusheng Cong, Xingzhi Xu
Pages: 1648-1652
Published online on: 10 March 2014

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Article

Isolinderalactone inhibits proliferation of A549 human non‑small cell lung cancer cells by arresting the cell cycle at the G0/G1 phase and inducing a Fas receptor and soluble Fas ligand-mediated apoptotic pathway

Wei-An Chang, En-Shyh Lin, Ming-Ju Tsai, Ming-Shyan Huang, Po-Lin Kuo
Pages: 1653-1659
Published online on: 06 March 2014

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Article

β‑glucan reduces exercise‑induced stress through downregulation of c‑Fos and c‑Jun expression in the brains of exhausted rats

Heeok Hong, Chang‑Ju Kim, Jae‑Deung Kim, Jin‑Hee Seo
Pages: 1660-1666
Published online on: 04 March 2014

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Article

CD44 affects the expression level of FOS‑like antigen 1 in cervical cancer tissues

Songshu Xiao, Yanhong Zhou, Jianfa Jiang, Le Yuan, Min Xue
Pages: 1667-1674
Published online on: 06 March 2014

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Article

Effects of hypoxia on progranulin expression in HT22 mouse hippocampal cells

Li Luo, Lanhai Lü, Yinghong Lu, Lihong Zhang, Bofei Li, Kaihua Guo, Lizhi Chen, Yang Wang, Yijia Shao, Jie Xu
Pages: 1675-1680
Published online on: 06 March 2014

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Article

Allelic methylation status of CpG islands on chromosome 21q in patients with Trisomy 21

Yin‑Yin Xia, Yu‑Bing Ding, Xue‑Qing Liu, Xue‑Mei Chen, Shu‑Qun Cheng, Lian‑Bing Li, Ming‑Fu Ma, Jun‑Lin He, Ying‑Xiong Wang
Pages: 1681-1688
Published online on: 25 February 2014

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Article

Correlation between the overexpression of urokinase receptor isoform uPAR (D1D2) and hepatic cell malignant transformation

Yingqun Zhou, Xiaoping Lǚ, Shan Li, Lingling Zhan
Pages: 1689-1696
Published online on: 04 March 2014

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Article

Colon cancer cells treated with 5‑fluorouracil exhibit changes in polylactosamine‑type N‑glycans

Liping Gao, Li Shen, Meiyun Yu, Jianlong Ni, Xiaoxia Dong, Yinghui Zhou, Shiliang Wu
Pages: 1697-1702
Published online on: 05 March 2014

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Article

microRNA‑206 overexpression inhibits cellular proliferation and invasion of estrogen receptor α‑positive ovarian cancer cells Retraction in /10.3892/mmr.2021.12279

Shaoru Li, Yan Li, Zhengfang Wen, Fanjing Kong, Xinlei Guan, Wenhui Liu
Pages: 1703-1708
Published online on: 06 March 2014

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Article

Protective effects of daphnetin on sodium taurocholate‑induced severe acute pancreatitis in rats

Zhi-Yong Liu, Jiao Liu, Kai-Liang Zhao, Li-Kun Wang, Qiao Shi, Teng Zuo, Tian-Yi Liu, Liang Zhao, Wei-Xing Wang
Pages: 1709-1714
Published online on: 28 February 2014

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Article

Changes in the gene expression levels of microRNAs in the rat hippocampus by sevoflurane and propofol anesthesia

Gentaro Goto, Yoko Hori, Masashi Ishikawa, Shunsuke Tanaka, Atsuhiro Sakamoto
Pages: 1715-1722
Published online on: 11 March 2014

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Article

Caveolin 1 knockdown inhibits the proliferation, migration and invasion of human breast cancer BT474 cells

Rui Wang, Zhi Li, Hui Guo, Wei Shi, Yue Xin, Weilong Chang, Tao Huang
Pages: 1723-1728
Published online on: 06 March 2014

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Article

Prostaglandin E2 upregulates β1 integrin expression via the E prostanoid 1 receptor/nuclear factor κ‑light‑chain‑enhancer of activated B cells pathway in non‑small‑cell lung cancer cells

Xiaoming Bai, Qinyi Yang, Wei Shu, Jie Wang, Li Zhang, Juan Ma, Shukai Xia, Min Zhang, Shanyu Cheng, Yipin Wang, Jing Leng
Pages: 1729-1736
Published online on: 28 February 2014

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Article

Retinitis pigmentosa‑associated rhodopsin mutant T17M induces endoplasmic reticulum (ER) stress and sensitizes cells to ER stress-induced cell death

Haibo Jiang, Siqi Xiong, Xiaobo Xia
Pages: 1737-1742
Published online on: 26 February 2014

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Article

Role of Nogo‑A in the regulation of hepatocellular carcinoma SMMC‑7721 cell apoptosis

Chun‑Qiu Hao, Yun Zhou, Jiu‑Ping Wang, Mei‑Jun Peng, Yu‑Mei Xie, Wen‑Zhen Kang, Li Sun, Ping‑Zhong Wang, Chun‑Ling Wan, Lin He, Lei Cai, Zhang‑Sheng Jia
Pages: 1743-1748
Published online on: 13 March 2014

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Article

Analysis of blood flow and local expression of angiogenesis‑associated growth factors in infected wounds treated with negative pressure wound therapy

Cheng‑Yan Xia, Ai‑Xi Yu, Baiwen Qi, Min Zhou, Zong‑Huan Li, Wei‑Yang Wang
Pages: 1749-1754
Published online on: 28 February 2014

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Article

Role of peroxisome proliferator‑activated receptor α in atherosclerosis

Heng Cao, Gao Wen, Hongli Li
Pages: 1755-1760
Published online on: 06 March 2014

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Article

Silencing ephrinB3 improves functional recovery following spinal cord injury

Yang Qu, Jianwu Zhao, Yang Wang, Zhongli Gao
Pages: 1761-1766
Published online on: 06 March 2014

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Article

Effects of canine myoblasts expressing human cartilage‑derived morphogenetic protein‑2 on the repair of meniscal fibrocartilage injury

Wen‑Hui Zhu, Yu‑Bin Wang, Liang Wang, Gu‑Feng Qiu, Liang‑Yu Lu
Pages: 1767-1772
Published online on: 13 March 2014

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Article

Cholera toxin, a typical protein kinase A activator, induces G1 phase growth arrest in human bladder transitional cell carcinoma cells via inhibiting the c‑Raf/MEK/ERK signaling pathway

Xiaoke Zheng, Yanqiu Ou, Minfeng Shu, Youqiong Wang, Yuxi  Zhou, Xingwen Su, Wenbo Zhu, Wei Yin, Shifeng Li, Pengxin  Qiu, Guangmei Yan, Jingxia Zhang, Jun Hu, Dong Xu
Pages: 1773-1779
Published online on: 14 March 2014

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Article

Translocation of protein kinase C δ contributes to the moderately high glucose‑, but not hypoxia‑induced proliferation in primary cultured human retinal endothelial cells

Zhao‑Chun Liu, En‑Hong Yu, Wei Liu, Xiao‑Chang Liu, Shi‑Bo Tang, Bang‑Hao Zhu
Pages: 1780-1786
Published online on: 13 March 2014

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Article

Targeting A549 lung adenocarcinoma cell growth and invasion with protease‑activated receptor‑1 siRNA

Zhuo Wu, Yanyan Zeng, Mingkang Zhong, Bin Wang
Pages: 1787-1793
Published online on: 06 March 2014

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Article

Transforming growth factor‑β1 in the microenvironment of ischemia reperfusion‑injured kidney enhances the chemotaxis of mesenchymal stem cells to stromal cell‑derived factor‑1 through upregulation of surface chemokine (C‑X‑C motif) receptor 4

Xiao‑Yun Si, Jing‑Jing Li, Tao Yao, Xiao‑Yan Wu
Pages: 1794-1798
Published online on: 26 February 2014

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Article

Mutation of isocitrate dehydrogenase 1 induces glioma cell proliferation via nuclear factor‑κB activation in a hypoxia‑inducible factor 1‑α dependent manner

GuoLiang Wang, Ke Sai, FangHe Gong, QunYing Yang, FuRong Chen, Jian Lin
Pages: 1799-1805
Published online on: 14 March 2014

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Article

Spatial expression of claudin family members in various organs of mice

Inho Hwang, Hyun Yang, Hong‑Seok Kang, Chang‑Hwan Ahn, Geun‑Shik Lee, Eui‑Ju Hong, Beum‑Soo An, Eui‑Bae Jeung
Pages: 1806-1812
Published online on: 10 March 2014

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Article

Inhibitory effects of Schisandra chinensis on acetaminophen-induced hepatotoxicity

Kun-Peng Wang, Yu Bai, Jian Wang, Jin-Zhen Zhang
Pages: 1813-1819
Published online on: 04 March 2014

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Article

MicroRNA‑125b suppresses the proliferation and osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells

Shi Chen, Liu Yang, Qiang Jie, Yan‑Shui Lin, Guo‑Lin Meng, Jin‑Zhu Fan, Jin‑Kang Zhang, Jing Fan, Zhuo‑Jing Luo, Jian Liu
Pages: 1820-1826
Published online on: 06 March 2014

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Article

Berberine ameliorates severe acute pancreatitis‑induced intestinal barrier dysfunction via a myosin light chain phosphorylation‑dependent pathway

Hong‑Yin Liang, Tao Chen, Hong‑Tao Yan, Zhu Huang, Li‑Jun Tang
Pages: 1827-1833
Published online on: 28 February 2014

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Article

IL-33 attenuates cardiac remodeling following myocardial infarction via inhibition of the p38 MAPK and NF-κB pathways Retraction in /10.3892/mmr.2022.12868

Honglei Yin, Peicheng Li, Fudong Hu, Yakun Wang, Xiaoyan Chai, Yan Zhang
Pages: 1834-1838
Published online on: 14 March 2014

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Article

Study of the effect of miR‑124 and the SOX9 target gene in Hirschsprung's disease

Jie Mi, Dong Chen, Mei Wu, Weilin Wang, Hong Gao
Pages: 1839-1843
Published online on: 06 March 2014

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Article

Standardization of the methylation‑specific PCR method for analyzing BRCA1 and ER methylation

Vo Thi Thuong Lan, Ngo Thi Ha, Nguyen Quynh Uyen, Nguyen Thi Duong, Nguyen Thi Thu Huong, Ta Bich Thuan, Pham Anh Thuy Duong, Ta Van To
Pages: 1844-1850
Published online on: 26 February 2014

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Article

Ac‑hE‑18A‑NH2, a novel dual‑domain apolipoprotein mimetic peptide, inhibits apoptosis in macrophages by promoting cholesterol efflux

Qiong Xie, Feng Li, Shui‑Ping Zhao
Pages: 1851-1856
Published online on: 14 March 2014

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Article

C242T polymorphism of the NADPH oxidase p22PHOX gene and its association with endothelial dysfunction in asymptomatic individuals with essential systemic hypertension

Adnan Rafiq, Khursheed Aslam, Rouf Malik, Dil Afroze
Pages: 1857-1862
Published online on: 26 February 2014

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Article

Isoproterenol‑mediated heme oxygenase‑1 induction inhibits high mobility group box 1 protein release and protects against rat myocardial ischemia/reperfusion injury in vivo

Jichun Wang, Xiaorong Hu, Wenwen Fu, Jing Xie, Xiaoya Zhou, Hong Jiang
Pages: 1863-1868
Published online on: 07 March 2014

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Article

Protective effects of the SEPS1 gene on lipopolysaccharide-induced sepsis

Lei He, Bin Wang, Yuan Yao, Maosheng Su, Huanxian Ma, Ning Jia
Pages: 1869-1876
Published online on: 26 February 2014

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Article

ROCK1, a novel target of miR-145, promotes glioma cell invasion

Xin Wan, Quan Cheng, Renjun Peng, Zhiming Ma, Zigui Chen, Yiqiang Cao, Bing Jiang
Pages: 1877-1882
Published online on: 25 February 2014

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Article

Berberine induces double-strand DNA breaks in Rev3 deficient cells

Xiaojuan Hu, Xiaohua Wu, Yunfei Huang, Qingyi Tong, Shunichi Takeda, Yong Qing
Pages: 1883-1888
Published online on: 28 February 2014

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Article

Effect of 20-hydroxyeicosatetraenoic acid on biological behavior of human villous trophoblasts and uterine vascular smooth muscle cells

Shuaijun Lu, Changling Zhu, Anxiong Long, Longyi Tan, Qian Li, Yuli Zhu
Pages: 1889-1894
Published online on: 06 March 2014

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Article

Co-stimulation with stem cell factor and erythropoietin enhances migration of c-Kit expressing cervical cancer cells through the sustained activation of ERK1/2

Cristina Aguilar, Cecilia Aguilar, Rebeca Lopez-Marure, Alejandro Jiménez-Sánchez, Leticia Rocha-Zavaleta
Pages: 1895-1902
Published online on: 12 March 2014

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Article

p53 N‑terminal binding and stabilisation by PIAS3 inhibits MDM2‑induced p53 ubiquitination and regulates cell growth

Ziyi Zhao, Lan Wu, Huimin Shi, Chuanfang Wu
Pages: 1903-1908
Published online on: 27 February 2014

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Article

microRNA‑125b promotes leukemia cell resistance to daunorubicin by inhibiting apoptosis

Lili Zhou, Haitao Bai, Chun Wang, Daolin Wei, Youwen Qin, Xiaowei Xu
Pages: 1909-1916
Published online on: 06 March 2014

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Article

microRNA‑9 attenuates amyloidβ‑induced synaptotoxicity by targeting calcium/calmodulin-dependent protein kinase kinase 2

Fei Chang, Lin‑Hong Zhang, Wu‑Ping Xu, Ping Jing, Pei‑Yan Zhan
Pages: 1917-1922
Published online on: 06 March 2014

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Article

β1‑adrenergic regulation of rapid component of delayed rectifier K+ currents in guinea‑pig cardiac myocytes

Sen Wang, Di Xu, Ting‑Ting Wu, Yan Guo, Yan‑Hong Chen, Jian‑Gang Zou
Pages: 1923-1928
Published online on: 10 March 2014

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Article

Phosphorylated Signal Transducer and Activator of Transcription 1 is a potential predictor of interferon response in patients with advanced renal cell carcinoma

Wei Li, Qiang Wei, Jianbo Liang
Pages: 1929-1934
Published online on: 13 March 2014

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Article

ADAM17 silencing suppresses the migration and invasion of non-small cell lung cancer

Xiaohong Lv, Yang Li, Ming Qian, Chengyuan Ma, Hongyu  Jing, Zhongmei Wen, Donghua Qian
Pages: 1935-1940
Published online on: 07 March 2014

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Hesperetin attenuates mitochondria-dependent apoptosis in lipopolysaccharide-induced H9C2 cardiomyocytes

Zheng Yang, Yuan Liu, Wei Deng, Jia Dai, Fangfang Li, Yuan Yuan, Qingqing Wu, Heng Zhou, Zhouyan Bian, Qizhu Tang
Pages: 1941-1946
Published online on: 04 March 2014

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Salvia miltiorrhiza increases the expression of transcription factor Foxp3 in experimental murine colitis

Dekui Xu, Hongbo Yu, Qinggong Yu, Simeng Wu, Dongmei Liu, Yan Lin, Ying Zhang, Changqing Zheng
Pages: 1947-1951
Published online on: 25 February 2014

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Embryo selection strategy in sibling oocytes: A novel approach to measuring the likelihood of single‑embryo transfer using a mouse embryo transfer model

Feng-Qin Xu, Rong Liu, Ying Ma, Li Liu, Ju-Yan Liang, Yan Ma
Pages: 1952-1958
Published online on: 28 February 2014

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Long‑term treatment of spontaneously hypertensive rats with losartan and molecular basis of modulating Ito of ventricular myocytes

Hongming Zhang, Songlin Wu, Congxing Huang, Xiaoyan Li
Pages: 1959-1967
Published online on: 28 February 2014

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Application of tension-free hernioplasty with hernia meshes of different materials and the postoperative effects on the reproductive function of male rats

Hao Xu, Ming Chen, Qianru Xu, Zhenlong Wang, Zhidong Qiu
Pages: 1968-1974
Published online on: 06 March 2014

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Autophagy prevents doxorubicin‑induced apoptosis in osteosarcoma

Dongxu Zhao, Hongping Yuan, Fei Yi, Chunyang Meng, Qingsan Zhu
Pages: 1975-1981
Published online on: 14 March 2014

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FOXO3a-mediated suppression of the self-renewal capacity of sphere-forming cells derived from the ovarian cancer SKOV3 cell line by 7-difluoromethoxyl-5,4'-di-n-octyl genistein Corrigendum in /10.3892/mmr.2021.12449

Yingxia Ning, Chaoyuan Luo, Kaiqun Ren, Meifang Quan, Jianguo Cao
Pages: 1982-1988
Published online on: 06 March 2014

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Magnetic resonance imaging‑directed biopsy improves the prediction of prostate cancer aggressiveness compared with a 12‑core transrectal ultrasound‑guided prostate biopsy

Jie Zhang, Jianjun Xiu, Yin Dong, Muwen Wang, Xue Han, Yejun Qin, Zhaoqin Huang, Shifeng Cai, Xianshun Yuan, Qingwei Liu
Pages: 1989-1997
Published online on: 28 February 2014

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Human heat shock protein 27 exacerbates ischemia reperfusion injury in rats by reducing the number of T regulatory cells

Sunyi Ye, Chenxi Zhang, Jie Zhou, Jun Cheng, Zhen Lv, Lin Zhou, Haiyang Xie, Jian Wu, Shusen Zheng
Pages: 1998-2002
Published online on: 10 March 2014

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Component analysis of Pu-erh and its anti-constipation effects

Guijie Li, Qiang Wang, Yu Qian, Yalin Zhou, Rui Wang, Xin Zhao
Pages: 2003-2009
Published online on: 05 March 2014

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Hepatitis C virus core protein induces hypoxia‑inducible factor 1α-mediated vascular endothelial growth factor expression in Huh7.5.1 cells

Chengliang Zhu, Xinghui Liu, Shiqun Wang, Xiaohong Yan, Zhaoming Tang, Kailang Wu, Yan Li, Fang Liu
Pages: 2010-2014
Published online on: 11 March 2014

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Decreased PPAR-γ expression in the conjunctiva and increased expression of TNF-α and IL-1β in the conjunctiva and tear fluid of dry eye mice

Yihui Chen, Xiaoyan Zhang, Ling Yang, Min Li, Bing Li, Weifang Wang, Minjie Sheng
Pages: 2015-2023
Published online on: 12 March 2014

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Telbivudine decreases proportion of peripheral blood CD4+CD25+CD127low T cells in parallel with inhibiting hepatitis B virus DNA

Zehui Yan, Jijun Zhou, Mengjun Zhang, Xiaolan Fu, Yuzhang Wu, Yuming Wang
Pages: 2024-2030
Published online on: 12 March 2014

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Analysis of mutational characteristics of the drug‑resistant gene katG in multi-drug resistant Mycobacterium tuberculosis L‑form among patients with pneumoconiosis complicated with tuberculosis

Jun Lu, Shan Jiang, Qian‑Ying Liu, Shuai Ma, Ying Li, Chao‑Pin Li
Pages: 2031-2035
Published online on: 13 March 2014

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Journal Cover
August-2026 Volume 34 Issue 2

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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Retraction Open Access

[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Article

Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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