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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2014 Volume 9 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis (Review)

Hiroshi Kobayashi, Shogo Imanaka, Haruki Nakamura, Ayumi Tsuji
Pages: 1483-1505
Published online on: 14 March 2014

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Review

Direct thrombin inhibitors: Patents 2002-2012 (Review)

Yi Kong, Hao Chen, Yong-Qing Wang, Ling Meng, Ji-Fu Wei
Pages: 1506-1514
Published online on: 06 March 2014

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Review Open Access

Limb-girdle muscular dystrophies: Where next after six decades from the first proposal (Review)

Omar A. Mahmood, Xin Mei Jiang
Pages: 1515-1532
Published online on: 13 March 2014

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Review

Monoamine oxidase inhibitors: Promising therapeutic agents for Alzheimer's disease (Review)

Zhiyou Cai
Pages: 1533-1541
Published online on: 11 March 2014

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Article

Molecular targets and mechanism of action of dexmedetomidine in treatment of ischemia/reperfusion injury

Ye Cai, Hui Xu, Jia Yan, Lei Zhang, Yi Lu
Pages: 1542-1550
Published online on: 10 March 2014

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Article Open Access

A pivotal role of the vascular endothelial growth factor signaling pathway in the formation of venous hypertension-induced dural arteriovenous fistulas

Qiang Li, Qi Zhang, Qing-Hai Huang, Yi-Bin Fang, Zhao-Long Zhang, Yi Xu, Jian-Min Liu
Pages: 1551-1558
Published online on: 11 March 2014

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Article Open Access

Prognostic performance of a series of model for end‑stage liver disease and respective Δ scores in patients with hepatitis B acute-on-chronic liver failure

Yun-Hao Xun, Jun-Ping Shi, Chun-Qing Li, Dan Li, Wei-Zhen Shi, Qing-Chun Pan, Jian-Chun Guo, Guo-Qing Zang
Pages: 1559-1568
Published online on: 25 February 2014

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Article Open Access

Anti-inflammatory and anti-proliferative effect of herbal medicines (APR) in RAW264.7 cells

Han-Seok Choi, Hye Sook Seo, Soon Re Kim, Youn Kyung Choi, Yong-Cheol Shin, Seong-Gyu Ko
Pages: 1569-1574
Published online on: 10 March 2014

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Article Open Access

The SDF-1/CXCR4 axis regulates migration of transplanted bone marrow mesenchymal stem cells towards the pancreas in rats with acute pancreatitis

Jian Gong, Hong-Bo Meng, Jie Hua, Zhen-Shun Song, Zhi‑Gang He, Bo Zhou, Ming-Ping Qian
Pages: 1575-1582
Published online on: 14 March 2014

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Article

Mesenchymal stem cell-based developmental endothelial locus-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice

Yun-Feng Zhao, Wei Xiong, Xue-Ling Wu
Pages: 1583-1589
Published online on: 26 February 2014

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Article

Apelin-13 stimulates angiogenesis by promoting cross‑talk between AMP-activated protein kinase and Akt signaling in myocardial microvascular endothelial cells

Xiaoman Yang, Wei Zhu, Pu Zhang, Kankai Chen, Lijie Zhao, Jingbo Li, Meng Wei, Mingya Liu
Pages: 1590-1596
Published online on: 25 February 2014

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Article Open Access

Pilot genome-wide study of tandem 3' UTRs in esophageal cancer using high-throughput sequencing

Mingzhong Sun, Huixiang Ju, Zhongwei Zhou, Rong Zhu
Pages: 1597-1605
Published online on: 04 March 2014

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Article

c-Jun transactivates Puma gene expression to promote osteoarthritis

Huading Lu, Gang Hou, Yongkai Zhang, Yuhu Dai, Huiqing Zhao
Pages: 1606-1612
Published online on: 24 February 2014

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Article Open Access

KLF8 knockdown suppresses proliferation and invasion in human osteosarcoma cells

Feng Lin, Zan Shen, Li‑Na Tang, Shui‑Er Zheng, Yuan‑Jue Sun, Da‑Liu Min, Yang Yao
Pages: 1613-1617
Published online on: 07 March 2014

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Article Open Access

Phosphodiesterase 3A rs7134375 single nucleotide polymorphism and serum lipid levels

Wei Wang, Rui‑Xing Yin, Dong‑Feng Wu, Lynn Htet Htet Aung, Ping Huang, Xiao‑Na Zeng, Ke‑Ke Huang, Quan‑Zhen Lin, Jian Wu, Tao Guo
Pages: 1618-1628
Published online on: 04 March 2014

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Article

Impaired hematopoiesis and delayed thrombopoietic recovery following sublethal irradiation in SRC‑3 knockout mice

J. Jin, Y. Wang, J. Wang, Y. Xu, S. L. Chen, J. P. Wang, Y. P. Su
Pages: 1629-1633
Published online on: 12 March 2014

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Article Open Access

Retinol binding protein 4 promotes hyperinsulinism‑induced proliferation of rat aortic smooth muscle cells

Fei Li, Ke Xia, Md Sayed Ali Sheikh, Jinfang Cheng, Chuanchang Li, Tianlun Yang
Pages: 1634-1640
Published online on: 07 March 2014

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Article Open Access

F‑actin cytoskeleton reorganization is associated with hepatic stellate cell activation

Xiaodong Cui, Xiaoyun Zhang, Qingling Yin, Aixia Meng, Shaojuan Su, Xu Jing, Hong Li, Xiumei Guan, Xin Li, Shunmei Liu, Min Cheng
Pages: 1641-1647
Published online on: 11 March 2014

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Article Open Access

Werner syndrome protein positively regulates XRCC4-like factor transcription

Dongyun Liu, Xiaoli Deng, Chongzhen Yuan, Lin Chen, Yusheng Cong, Xingzhi Xu
Pages: 1648-1652
Published online on: 10 March 2014

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Article

Isolinderalactone inhibits proliferation of A549 human non‑small cell lung cancer cells by arresting the cell cycle at the G0/G1 phase and inducing a Fas receptor and soluble Fas ligand-mediated apoptotic pathway

Wei-An Chang, En-Shyh Lin, Ming-Ju Tsai, Ming-Shyan Huang, Po-Lin Kuo
Pages: 1653-1659
Published online on: 06 March 2014

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Article

β‑glucan reduces exercise‑induced stress through downregulation of c‑Fos and c‑Jun expression in the brains of exhausted rats

Heeok Hong, Chang‑Ju Kim, Jae‑Deung Kim, Jin‑Hee Seo
Pages: 1660-1666
Published online on: 04 March 2014

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Article

CD44 affects the expression level of FOS‑like antigen 1 in cervical cancer tissues

Songshu Xiao, Yanhong Zhou, Jianfa Jiang, Le Yuan, Min Xue
Pages: 1667-1674
Published online on: 06 March 2014

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Article

Effects of hypoxia on progranulin expression in HT22 mouse hippocampal cells

Li Luo, Lanhai Lü, Yinghong Lu, Lihong Zhang, Bofei Li, Kaihua Guo, Lizhi Chen, Yang Wang, Yijia Shao, Jie Xu
Pages: 1675-1680
Published online on: 06 March 2014

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Article

Allelic methylation status of CpG islands on chromosome 21q in patients with Trisomy 21

Yin‑Yin Xia, Yu‑Bing Ding, Xue‑Qing Liu, Xue‑Mei Chen, Shu‑Qun Cheng, Lian‑Bing Li, Ming‑Fu Ma, Jun‑Lin He, Ying‑Xiong Wang
Pages: 1681-1688
Published online on: 25 February 2014

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Article

Correlation between the overexpression of urokinase receptor isoform uPAR (D1D2) and hepatic cell malignant transformation

Yingqun Zhou, Xiaoping Lǚ, Shan Li, Lingling Zhan
Pages: 1689-1696
Published online on: 04 March 2014

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Article

Colon cancer cells treated with 5‑fluorouracil exhibit changes in polylactosamine‑type N‑glycans

Liping Gao, Li Shen, Meiyun Yu, Jianlong Ni, Xiaoxia Dong, Yinghui Zhou, Shiliang Wu
Pages: 1697-1702
Published online on: 05 March 2014

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Article

microRNA‑206 overexpression inhibits cellular proliferation and invasion of estrogen receptor α‑positive ovarian cancer cells Retraction in /10.3892/mmr.2021.12279

Shaoru Li, Yan Li, Zhengfang Wen, Fanjing Kong, Xinlei Guan, Wenhui Liu
Pages: 1703-1708
Published online on: 06 March 2014

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Article

Protective effects of daphnetin on sodium taurocholate‑induced severe acute pancreatitis in rats

Zhi-Yong Liu, Jiao Liu, Kai-Liang Zhao, Li-Kun Wang, Qiao Shi, Teng Zuo, Tian-Yi Liu, Liang Zhao, Wei-Xing Wang
Pages: 1709-1714
Published online on: 28 February 2014

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Article

Changes in the gene expression levels of microRNAs in the rat hippocampus by sevoflurane and propofol anesthesia

Gentaro Goto, Yoko Hori, Masashi Ishikawa, Shunsuke Tanaka, Atsuhiro Sakamoto
Pages: 1715-1722
Published online on: 11 March 2014

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Article

Caveolin 1 knockdown inhibits the proliferation, migration and invasion of human breast cancer BT474 cells

Rui Wang, Zhi Li, Hui Guo, Wei Shi, Yue Xin, Weilong Chang, Tao Huang
Pages: 1723-1728
Published online on: 06 March 2014

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Article

Prostaglandin E2 upregulates β1 integrin expression via the E prostanoid 1 receptor/nuclear factor κ‑light‑chain‑enhancer of activated B cells pathway in non‑small‑cell lung cancer cells

Xiaoming Bai, Qinyi Yang, Wei Shu, Jie Wang, Li Zhang, Juan Ma, Shukai Xia, Min Zhang, Shanyu Cheng, Yipin Wang, Jing Leng
Pages: 1729-1736
Published online on: 28 February 2014

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Article

Retinitis pigmentosa‑associated rhodopsin mutant T17M induces endoplasmic reticulum (ER) stress and sensitizes cells to ER stress-induced cell death

Haibo Jiang, Siqi Xiong, Xiaobo Xia
Pages: 1737-1742
Published online on: 26 February 2014

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Article

Role of Nogo‑A in the regulation of hepatocellular carcinoma SMMC‑7721 cell apoptosis

Chun‑Qiu Hao, Yun Zhou, Jiu‑Ping Wang, Mei‑Jun Peng, Yu‑Mei Xie, Wen‑Zhen Kang, Li Sun, Ping‑Zhong Wang, Chun‑Ling Wan, Lin He, Lei Cai, Zhang‑Sheng Jia
Pages: 1743-1748
Published online on: 13 March 2014

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Article

Analysis of blood flow and local expression of angiogenesis‑associated growth factors in infected wounds treated with negative pressure wound therapy

Cheng‑Yan Xia, Ai‑Xi Yu, Baiwen Qi, Min Zhou, Zong‑Huan Li, Wei‑Yang Wang
Pages: 1749-1754
Published online on: 28 February 2014

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Article

Role of peroxisome proliferator‑activated receptor α in atherosclerosis

Heng Cao, Gao Wen, Hongli Li
Pages: 1755-1760
Published online on: 06 March 2014

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Article

Silencing ephrinB3 improves functional recovery following spinal cord injury

Yang Qu, Jianwu Zhao, Yang Wang, Zhongli Gao
Pages: 1761-1766
Published online on: 06 March 2014

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Article

Effects of canine myoblasts expressing human cartilage‑derived morphogenetic protein‑2 on the repair of meniscal fibrocartilage injury

Wen‑Hui Zhu, Yu‑Bin Wang, Liang Wang, Gu‑Feng Qiu, Liang‑Yu Lu
Pages: 1767-1772
Published online on: 13 March 2014

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Article

Cholera toxin, a typical protein kinase A activator, induces G1 phase growth arrest in human bladder transitional cell carcinoma cells via inhibiting the c‑Raf/MEK/ERK signaling pathway

Xiaoke Zheng, Yanqiu Ou, Minfeng Shu, Youqiong Wang, Yuxi  Zhou, Xingwen Su, Wenbo Zhu, Wei Yin, Shifeng Li, Pengxin  Qiu, Guangmei Yan, Jingxia Zhang, Jun Hu, Dong Xu
Pages: 1773-1779
Published online on: 14 March 2014

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Article

Translocation of protein kinase C δ contributes to the moderately high glucose‑, but not hypoxia‑induced proliferation in primary cultured human retinal endothelial cells

Zhao‑Chun Liu, En‑Hong Yu, Wei Liu, Xiao‑Chang Liu, Shi‑Bo Tang, Bang‑Hao Zhu
Pages: 1780-1786
Published online on: 13 March 2014

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Article

Targeting A549 lung adenocarcinoma cell growth and invasion with protease‑activated receptor‑1 siRNA

Zhuo Wu, Yanyan Zeng, Mingkang Zhong, Bin Wang
Pages: 1787-1793
Published online on: 06 March 2014

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Article

Transforming growth factor‑β1 in the microenvironment of ischemia reperfusion‑injured kidney enhances the chemotaxis of mesenchymal stem cells to stromal cell‑derived factor‑1 through upregulation of surface chemokine (C‑X‑C motif) receptor 4

Xiao‑Yun Si, Jing‑Jing Li, Tao Yao, Xiao‑Yan Wu
Pages: 1794-1798
Published online on: 26 February 2014

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Article

Mutation of isocitrate dehydrogenase 1 induces glioma cell proliferation via nuclear factor‑κB activation in a hypoxia‑inducible factor 1‑α dependent manner

GuoLiang Wang, Ke Sai, FangHe Gong, QunYing Yang, FuRong Chen, Jian Lin
Pages: 1799-1805
Published online on: 14 March 2014

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Article

Spatial expression of claudin family members in various organs of mice

Inho Hwang, Hyun Yang, Hong‑Seok Kang, Chang‑Hwan Ahn, Geun‑Shik Lee, Eui‑Ju Hong, Beum‑Soo An, Eui‑Bae Jeung
Pages: 1806-1812
Published online on: 10 March 2014

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Article

Inhibitory effects of Schisandra chinensis on acetaminophen-induced hepatotoxicity

Kun-Peng Wang, Yu Bai, Jian Wang, Jin-Zhen Zhang
Pages: 1813-1819
Published online on: 04 March 2014

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Article

MicroRNA‑125b suppresses the proliferation and osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells

Shi Chen, Liu Yang, Qiang Jie, Yan‑Shui Lin, Guo‑Lin Meng, Jin‑Zhu Fan, Jin‑Kang Zhang, Jing Fan, Zhuo‑Jing Luo, Jian Liu
Pages: 1820-1826
Published online on: 06 March 2014

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Article

Berberine ameliorates severe acute pancreatitis‑induced intestinal barrier dysfunction via a myosin light chain phosphorylation‑dependent pathway

Hong‑Yin Liang, Tao Chen, Hong‑Tao Yan, Zhu Huang, Li‑Jun Tang
Pages: 1827-1833
Published online on: 28 February 2014

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Article

IL-33 attenuates cardiac remodeling following myocardial infarction via inhibition of the p38 MAPK and NF-κB pathways Retraction in /10.3892/mmr.2022.12868

Honglei Yin, Peicheng Li, Fudong Hu, Yakun Wang, Xiaoyan Chai, Yan Zhang
Pages: 1834-1838
Published online on: 14 March 2014

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Article

Study of the effect of miR‑124 and the SOX9 target gene in Hirschsprung's disease

Jie Mi, Dong Chen, Mei Wu, Weilin Wang, Hong Gao
Pages: 1839-1843
Published online on: 06 March 2014

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Article

Standardization of the methylation‑specific PCR method for analyzing BRCA1 and ER methylation

Vo Thi Thuong Lan, Ngo Thi Ha, Nguyen Quynh Uyen, Nguyen Thi Duong, Nguyen Thi Thu Huong, Ta Bich Thuan, Pham Anh Thuy Duong, Ta Van To
Pages: 1844-1850
Published online on: 26 February 2014

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Article

Ac‑hE‑18A‑NH2, a novel dual‑domain apolipoprotein mimetic peptide, inhibits apoptosis in macrophages by promoting cholesterol efflux

Qiong Xie, Feng Li, Shui‑Ping Zhao
Pages: 1851-1856
Published online on: 14 March 2014

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Article

C242T polymorphism of the NADPH oxidase p22PHOX gene and its association with endothelial dysfunction in asymptomatic individuals with essential systemic hypertension

Adnan Rafiq, Khursheed Aslam, Rouf Malik, Dil Afroze
Pages: 1857-1862
Published online on: 26 February 2014

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Article

Isoproterenol‑mediated heme oxygenase‑1 induction inhibits high mobility group box 1 protein release and protects against rat myocardial ischemia/reperfusion injury in vivo

Jichun Wang, Xiaorong Hu, Wenwen Fu, Jing Xie, Xiaoya Zhou, Hong Jiang
Pages: 1863-1868
Published online on: 07 March 2014

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Article

Protective effects of the SEPS1 gene on lipopolysaccharide-induced sepsis

Lei He, Bin Wang, Yuan Yao, Maosheng Su, Huanxian Ma, Ning Jia
Pages: 1869-1876
Published online on: 26 February 2014

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Article

ROCK1, a novel target of miR-145, promotes glioma cell invasion

Xin Wan, Quan Cheng, Renjun Peng, Zhiming Ma, Zigui Chen, Yiqiang Cao, Bing Jiang
Pages: 1877-1882
Published online on: 25 February 2014

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Article

Berberine induces double-strand DNA breaks in Rev3 deficient cells

Xiaojuan Hu, Xiaohua Wu, Yunfei Huang, Qingyi Tong, Shunichi Takeda, Yong Qing
Pages: 1883-1888
Published online on: 28 February 2014

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Article

Effect of 20-hydroxyeicosatetraenoic acid on biological behavior of human villous trophoblasts and uterine vascular smooth muscle cells

Shuaijun Lu, Changling Zhu, Anxiong Long, Longyi Tan, Qian Li, Yuli Zhu
Pages: 1889-1894
Published online on: 06 March 2014

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Article

Co-stimulation with stem cell factor and erythropoietin enhances migration of c-Kit expressing cervical cancer cells through the sustained activation of ERK1/2

Cristina Aguilar, Cecilia Aguilar, Rebeca Lopez-Marure, Alejandro Jiménez-Sánchez, Leticia Rocha-Zavaleta
Pages: 1895-1902
Published online on: 12 March 2014

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Article

p53 N‑terminal binding and stabilisation by PIAS3 inhibits MDM2‑induced p53 ubiquitination and regulates cell growth

Ziyi Zhao, Lan Wu, Huimin Shi, Chuanfang Wu
Pages: 1903-1908
Published online on: 27 February 2014

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Article

microRNA‑125b promotes leukemia cell resistance to daunorubicin by inhibiting apoptosis

Lili Zhou, Haitao Bai, Chun Wang, Daolin Wei, Youwen Qin, Xiaowei Xu
Pages: 1909-1916
Published online on: 06 March 2014

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Article

microRNA‑9 attenuates amyloidβ‑induced synaptotoxicity by targeting calcium/calmodulin-dependent protein kinase kinase 2

Fei Chang, Lin‑Hong Zhang, Wu‑Ping Xu, Ping Jing, Pei‑Yan Zhan
Pages: 1917-1922
Published online on: 06 March 2014

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Article

β1‑adrenergic regulation of rapid component of delayed rectifier K+ currents in guinea‑pig cardiac myocytes

Sen Wang, Di Xu, Ting‑Ting Wu, Yan Guo, Yan‑Hong Chen, Jian‑Gang Zou
Pages: 1923-1928
Published online on: 10 March 2014

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Article

Phosphorylated Signal Transducer and Activator of Transcription 1 is a potential predictor of interferon response in patients with advanced renal cell carcinoma

Wei Li, Qiang Wei, Jianbo Liang
Pages: 1929-1934
Published online on: 13 March 2014

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Article

ADAM17 silencing suppresses the migration and invasion of non-small cell lung cancer

Xiaohong Lv, Yang Li, Ming Qian, Chengyuan Ma, Hongyu  Jing, Zhongmei Wen, Donghua Qian
Pages: 1935-1940
Published online on: 07 March 2014

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Hesperetin attenuates mitochondria-dependent apoptosis in lipopolysaccharide-induced H9C2 cardiomyocytes

Zheng Yang, Yuan Liu, Wei Deng, Jia Dai, Fangfang Li, Yuan Yuan, Qingqing Wu, Heng Zhou, Zhouyan Bian, Qizhu Tang
Pages: 1941-1946
Published online on: 04 March 2014

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Salvia miltiorrhiza increases the expression of transcription factor Foxp3 in experimental murine colitis

Dekui Xu, Hongbo Yu, Qinggong Yu, Simeng Wu, Dongmei Liu, Yan Lin, Ying Zhang, Changqing Zheng
Pages: 1947-1951
Published online on: 25 February 2014

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Embryo selection strategy in sibling oocytes: A novel approach to measuring the likelihood of single‑embryo transfer using a mouse embryo transfer model

Feng-Qin Xu, Rong Liu, Ying Ma, Li Liu, Ju-Yan Liang, Yan Ma
Pages: 1952-1958
Published online on: 28 February 2014

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Long‑term treatment of spontaneously hypertensive rats with losartan and molecular basis of modulating Ito of ventricular myocytes

Hongming Zhang, Songlin Wu, Congxing Huang, Xiaoyan Li
Pages: 1959-1967
Published online on: 28 February 2014

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Application of tension-free hernioplasty with hernia meshes of different materials and the postoperative effects on the reproductive function of male rats

Hao Xu, Ming Chen, Qianru Xu, Zhenlong Wang, Zhidong Qiu
Pages: 1968-1974
Published online on: 06 March 2014

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Autophagy prevents doxorubicin‑induced apoptosis in osteosarcoma

Dongxu Zhao, Hongping Yuan, Fei Yi, Chunyang Meng, Qingsan Zhu
Pages: 1975-1981
Published online on: 14 March 2014

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FOXO3a-mediated suppression of the self-renewal capacity of sphere-forming cells derived from the ovarian cancer SKOV3 cell line by 7-difluoromethoxyl-5,4'-di-n-octyl genistein Corrigendum in /10.3892/mmr.2021.12449

Yingxia Ning, Chaoyuan Luo, Kaiqun Ren, Meifang Quan, Jianguo Cao
Pages: 1982-1988
Published online on: 06 March 2014

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Magnetic resonance imaging‑directed biopsy improves the prediction of prostate cancer aggressiveness compared with a 12‑core transrectal ultrasound‑guided prostate biopsy

Jie Zhang, Jianjun Xiu, Yin Dong, Muwen Wang, Xue Han, Yejun Qin, Zhaoqin Huang, Shifeng Cai, Xianshun Yuan, Qingwei Liu
Pages: 1989-1997
Published online on: 28 February 2014

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Human heat shock protein 27 exacerbates ischemia reperfusion injury in rats by reducing the number of T regulatory cells

Sunyi Ye, Chenxi Zhang, Jie Zhou, Jun Cheng, Zhen Lv, Lin Zhou, Haiyang Xie, Jian Wu, Shusen Zheng
Pages: 1998-2002
Published online on: 10 March 2014

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Component analysis of Pu-erh and its anti-constipation effects

Guijie Li, Qiang Wang, Yu Qian, Yalin Zhou, Rui Wang, Xin Zhao
Pages: 2003-2009
Published online on: 05 March 2014

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Hepatitis C virus core protein induces hypoxia‑inducible factor 1α-mediated vascular endothelial growth factor expression in Huh7.5.1 cells

Chengliang Zhu, Xinghui Liu, Shiqun Wang, Xiaohong Yan, Zhaoming Tang, Kailang Wu, Yan Li, Fang Liu
Pages: 2010-2014
Published online on: 11 March 2014

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Article

Decreased PPAR-γ expression in the conjunctiva and increased expression of TNF-α and IL-1β in the conjunctiva and tear fluid of dry eye mice

Yihui Chen, Xiaoyan Zhang, Ling Yang, Min Li, Bing Li, Weifang Wang, Minjie Sheng
Pages: 2015-2023
Published online on: 12 March 2014

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Telbivudine decreases proportion of peripheral blood CD4+CD25+CD127low T cells in parallel with inhibiting hepatitis B virus DNA

Zehui Yan, Jijun Zhou, Mengjun Zhang, Xiaolan Fu, Yuzhang Wu, Yuming Wang
Pages: 2024-2030
Published online on: 12 March 2014

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Article

Analysis of mutational characteristics of the drug‑resistant gene katG in multi-drug resistant Mycobacterium tuberculosis L‑form among patients with pneumoconiosis complicated with tuberculosis

Jun Lu, Shan Jiang, Qian‑Ying Liu, Shuai Ma, Ying Li, Chao‑Pin Li
Pages: 2031-2035
Published online on: 13 March 2014

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Journal Cover
May-2026 Volume 33 Issue 5

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Identification of STMN1 as a lactylation‑related driver of lung cancer progression using Mendelian randomization

Yifan Cai, Yucheng Zhong, Honglin Wang, Shuang Zhu, Fang Huang, Qiuyue Zhang, Shaobo Hu
Article Number: 156
Published online on: 30 March 2026

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Advances in the mechanisms of extracellular vesicles and circulating tumor cells in hepatocellular carcinoma metastasis (Review)

Sitong Yi, Wenxin Liu, Zhaohui Wang
Article Number: 155
Published online on: 30 March 2026

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Diagnostic importance of serum markers in lung cancer

Qichen Liang, Jianmei Song, Haixiang Wei, Lu Ning, Baoyu He, Ziteng Zhang
Article Number: 154
Published online on: 30 March 2026

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VSNL1 attenuates hypoxia‑induced myocardial apoptosis by regulating the CNP/NPRB pathway

Xing Yang, Wenjuan Fang, Rui Chang, Linlin Ma, Xiaoyan Chen, Yanfei Li
Article Number: 153
Published online on: 30 March 2026

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Stabilin‑1: An immunoregulatory scavenger receptor in inflammation and tissue homeostasis (Review)

Xiao-Lei Xiang, Xin-Tong Ye, Yu-Tong Wu, Chen Chen, Chu-Ying Yu, Su-Ting Qian, Dan-Li Cai
Article Number: 152
Published online on: 26 March 2026

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Mechanism and therapeutic prospects of adipose tissue B lymphocytes in obesity and obesity‑associated metabolic diseases (Review)

Hong Wang, Hongyuan Lv, Xiaolin Zhang, Meifang Liu, Liyuan Wang
Article Number: 151
Published online on: 26 March 2026

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Tonsil‑derived mesenchymal stem cell‑derived extracellular vesicles suppress MAPK‑NF‑κB signaling and restore osteogenic differentiation in LPS‑stimulated periodontal ligament fibroblasts

Won-Jung Bae, Su Kang Kim, Han-Soo Kim, Sang Wook Kang, Ju Yeon Ban
Article Number: 150
Published online on: 26 March 2026

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Succinylation modification in diabetes and diabetic complications: Mechanisms and functions (Review)

Yeteng Xiong, Fei Luo, Bingnan Li, Qinfeng Yang
Article Number: 149
Published online on: 26 March 2026

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Polyphyllin II regulates ROS levels and promotes ferroptosis in bladder cancer cells

Quanlai Qiao, Ruifang Guo, Zhonghua Sun, Yaxin Shi, Yuning Xie, Zhiyong Liu
Article Number: 148
Published online on: 26 March 2026

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Veronicastrum sibiricum (L.) Pennell extract alleviates inflammation‑induced muscle atrophy through NLRP3 inflammasome regulation and mitochondrial function restoration

Eunhye Lee, Minjeong Kwon, Ju-Ock Nam
Article Number: 147
Published online on: 26 March 2026

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Role and clinical importance of lactylation in tumors (Review)

Chaowei Zhang, Xinyu Tang, Yuxuan Han, Weiyi Yao, Qing Hong, Yanan Zhu, Na Chen
Article Number: 146
Published online on: 26 March 2026

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Photodynamic therapy: A paradigm shift in overcoming drug‑resistant tuberculosis (Review)

Shuhao Cheng, Yuqing Wang, Jie Yao, Guodong Cheng, Gengzhi Ye, Fapeng Shi, Xiaolei Ma
Article Number: 145
Published online on: 26 March 2026

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Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review)

Yiyu Qin, Yang Zhou
Article Number: 144
Published online on: 26 March 2026

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Retraction Open Access

[Retracted] Na+/K+‑ATPase DR region‑specific antibody protects U251 cells against hypoxia reperfusion‑induced injury via the PI3K/AKT and ERK pathways

Huilin Gong, Pengbiao Lü, Jiangwei Zhang, Dandong Li, Jin Zheng, Jinning Song
Article Number: 143
Published online on: 23 March 2026

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Multi‑omics and their integration in psoriasis research (Review)

Hengyan Zhang, Danping Li, Lijuan Zhu, Heguo Yan, Licong Yang, Xuesong Yang, Ye Zhou
Article Number: 142
Published online on: 23 March 2026

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LDHA protects vascular endothelial cells from oxidative stress‑induced mitochondrial damage via HIF‑1α activation and glycolytic reprogramming

Beibei Dai, Lili Yang, Yu Zhang, Aiyong Yu
Article Number: 141
Published online on: 23 March 2026

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Article

Mechanism of BRCC36 affecting cardiac rupture after acute infarction through the Wnt‑JNK signaling pathway

Yongzhe Guo, Linyan Chen, Shumei Li, Xintao Zhang, Huizhong Lin
Article Number: 140
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway

Ping Niu, Yuxuan Sun, Shiyi Wang, Guang Li, Xiaomin Tang, Jiaqiang Sun, Chunchen Pan, Jingwu Sun
Article Number: 139
Published online on: 19 March 2026

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Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review)

Honghui You, Xiangjun Tang, Xiaoyan Fu, Jiaqi Zhou, Liyuan Wang, Hongxia Zhang, Xianhong Du, Shujuan Liang, Meifang Liu
Article Number: 138
Published online on: 19 March 2026

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Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review)

Yanling Qin, Chenqi Tang, Sen Tan, Guangnan Liu
Article Number: 137
Published online on: 18 March 2026

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Advances in the biological functions of miR‑205 in various diseases (Review)

Dandan Chai, Hua Du, Yingxu Shi
Article Number: 136
Published online on: 18 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Article Number: 135
Published online on: 16 March 2026

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Precision medicine approach to coronary artery disease: Haptoglobin phenotype‑guided risk assessment

Zhengxin He, Hong Liu, Keran Jia, Daxin Lei, Liyun An, Jia Wang, Fukun Wang
Article Number: 134
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling

Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao
Article Number: 133
Published online on: 11 March 2026

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Glucose‑driven TRIB3 enhances the tumorigenic potential of colon cancer via the PI3K/AKT pathway

Yunting Bai, Xuying Huang, Guangyu An, Yang Ge, Rui Yan, Dan Yu
Article Number: 132
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8

Yan-Yan Bai, Jun-Zhi Niu
Article Number: 131
Published online on: 09 March 2026

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Dexmedetomidine protects against myocardial ischemia reperfusion injury by inhibiting the TLR2‑NF‑κB pathway in diabetic mice

Zhengjie Chen, Liangyu Zheng, Gang Chen
Article Number: 130
Published online on: 06 March 2026

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Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis

Yu Han, Siqi Yang, Jing Zhang, Yaoguang Wang, Xi Zhao, Huan Liu
Article Number: 129
Published online on: 05 March 2026

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Retraction Open Access

[Retracted] Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Article Number: 128
Published online on: 05 March 2026

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Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 33 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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