|
1
|
Murakami Y, Saigo K, Takashima H, Minami
M, Okanoue T, Bréchot C and Paterlini-Bréchot P: Large scaled
analysis of hepatitis B virus (HBV) DNA integration in HBV related
hepatocellular carcinomas. Gut. 54:1162–1168. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Saigo K, Yoshida K, Ikeda R, Sakamoto Y,
Murakami Y, Urashima T, Asano T, Kenmochi T and Inoue I:
Integration of hepatitis B virus DNA into the myeloidl/ymphoid or
mixed-lineage leukemia (MLL4) gene and rearrangements of MLL4 in
human hepatocellular carcinoma. Hum Mutat. 29:703–708. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Murakami Y, Minami M, Daimon Y and Okanoue
T: Hepatitis B virus DNA in liver, serum and peripheral blood
mononuclear cells after the clearance of serum hepatitis B virus
surface antigen. J Med Virol. 72:203–214. 2004. View Article : Google Scholar
|
|
4
|
Jiang Z, Jhunjhunwala S, Liu J, Haverty
PM, Kennemer MI, Guan Y, Lee W, Carnevali P, Stinson J, Johnson S,
et al: The effects of hepatitis B virus integration into the
genomes of hepa-tocellular carcinoma patients. Genome Res.
22:593–601. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Sung WK, Zheng H, Li S, Chen R, Liu X, Li
Y, Lee NP, Lee WH, Ariyaratne PN, Tennakoon C, et al: Genome-wide
survey of recurrent HBV integration in hepatocellular carcinoma.
Nat Genet. 44:765–769. 2012. View
Article : Google Scholar : PubMed/NCBI
|
|
6
|
Toh ST, Jin Y, Liu L, Wang J, Babrzadeh F,
Gharizadeh B, Ronaghi M, Toh HC, Chow PK, Chung AY, et al: Deep
sequencing of the hepatitis B virus in hepatocellular carcinoma
patients reveals enriched integration events, structural
alterations and sequence variations. Carcinogenesis. 34:787–798.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Chinese Society of Hepatology and Chinese
Society of Infectious Diseases; Chinese Medical Association: The
guideline of prevention and treatment for chronic hepatitis B (2010
version). Zhonghua Gan Zang Bing Za Zhi. 19:13–24. 2011.In
Chinese.
|
|
8
|
Bowden S, Jackson K, Littlejohn M and
Locarnini S: Quantification of HBV covalently closed circular DNA
from liver tissue by real-time PCR. Methods Mol Med. 95:41–50.
2004.PubMed/NCBI
|
|
9
|
Weinberger KM, Wiedenmann E, Böhm S and
Jilg W: Sensitive and accurate quantitation of hepatitis B virus
DNA using a kinetic fluorescence detection system (TaqMan PCR). J
Virol Methods. 85:75–82. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Ruan P, Zhou B, Dai X, Sun Z, Guo X, Huang
J and Gong Z: Predictive value of intrahepatic hepatitis B virus
covalently closed circular DNA and total DNA in patients with acute
hepatitis B and patients with chronic hepatitis B receiving
anti-viral treatment. Mol Med Rep. 9:1135–1141. 2014.PubMed/NCBI
|
|
11
|
Belloni L, Allweiss L, Guerrieri F,
Pediconi N, Volz T, Pollicino T, Petersen J, Raimondo G, Dandri M
and Levrero M: IFN-α inhibits HBV transcription and replication in
cell culture and in humanized mice by targeting the epigenetic
regulation of the nuclear cccDNA minichromosome. J Clin Invest.
122:529–537. 2012. View
Article : Google Scholar : PubMed/NCBI
|
|
12
|
Chou YC, Jeng KS, Chen ML, Liu HH, Liu TL,
Chen YL, Liu YC, Hu CP and Chang C: Evaluation of transcriptional
efficiency of hepatitis B virus covalently closed circular DNA by
reverse transcription-PCR combined with the restriction enzyme
digestion method. J Virol. 79:1813–1823. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Fujimoto A, Totoki Y, Abe T, Boroevich KA,
Hosoda F, Nguyen HH, Aoki M, Hosono N, Kubo M, Miya F, et al:
Whole-genome sequencing of liver cancers identifies etiological
influences on mutation patterns and recurrent mutations in
chromatin regulators. Nat Genet. 44:760–764. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Li WY, Zeng X, Lee NP, Liu X, Chen S, Guo
B, Yi S, Zhuang X, Chen F, Wang G, et al: HIVID: An efficient
method to detect HBV integration using low coverage sequencing.
Genomics. 102:338–344. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Li X, Zhang J, Yang Z, Kang J, Jiang S,
Zhang T, Chen T, Li M, Lv Q, Chen X, et al: The function of
targeted host genes determines the oncogenicity of HBV integration
in hepatocellular carcinoma. J Hepatol. 60:975–984. 2014.
View Article : Google Scholar
|
|
16
|
Ding D, Lou X, Hua D, Yu W, Li L, Wang J,
Gao F, Zhao N, Ren G, Li L and Lin B: Recurrent targeted genes of
hepatitis B virus in the liver cancer genomes identified by a
next-generation sequencing-based approach. PLoS Genet.
8:e10030652012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Bohne F, Chmielewski M, Ebert G, Wiegmann
K, Kürschner T, Schulze A, Urban S, Krönke M, Abken H and Protzer
U: T cells redirected against hepatitis B virus surface proteins
eliminate infected hepatocytes. Gastroenterology. 134:239–247.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Krebs K, Böttinger N, Huang LR,
Chmielewski M, Arzberger S, Gasteiger G, Jäger C, Schmitt E, Bohne
F, Aichler M, et al: T cells expressing a chimeric antigen receptor
that binds hepatitis B virus envelope proteins control virus
replication in mice. Gastroenterology. 145:456–465. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Díaz-Montero CM, Naga O, Zidan AA, Salem
ML, Pallin M, Parmigiani A, Walker G, Wieder E, Komanduri K, Cole
DJ, et al: Synergy of brief activation of CD8 T-cells in the
presence of IL-12 and adoptive transfer into lymphopenic hosts
promotes tumor clearance and anti-tumor memory. Am J Cancer Res.
1:882–896. 2011.PubMed/NCBI
|
|
20
|
Vemuru RP, Aragona E and Gupta S: Analysis
of hepatocellular proliferation: study of archival liver tissue is
facilitated by an endogenous marker of DNA replication. Hepatology.
16:968–973. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hagen TM, Huang S, Curnutte J, Fowler P,
Martinez V, Wehr CM, Ames BN and Chisari FV: Extensive oxidative
DNA damage in hepatocytes of transgenic mice with chronic active
hepatitis destined to develop hepatocellular carcinoma. Proc Natl
Acad Sci USA. 91:12808–12812. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Mason WS, Jilbert AR and Summers J: Clonal
expansion of hepatocytes during chronic woodchuck hepatitis virus
infection. Proc Natl Acad Sci USA. 102:1139–1144. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Mason WS, Liu C, Aldrich CE, Litwin S and
Yeh MM: Clonal expansion of normal-appearing human hepatocytes
during chronic hepatitis B virus infection. J Virol. 84:8308–8315.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Mason WS, Low CL, Xu C, Aldrich CE,
Scougall CA, Grosse A, Clouston A, Chavez D, Litwin S, Peri S, et
al: Detection of clonally expanded hepatocytes in chimpanzees with
chronic hepatitis B virus infection. J Virol. 83:8396–8408. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Volz T, Lutgehetmann M, Wachtler P, Jacob
A, Quaas A, Murray JM, Dandri M and Petersen J: Impaired
intrahepatic hepatitis B virus productivity contributes to low
viremia in most HBeAg-negative patients. Gastroenterology.
133:843–852. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Nguyen T, Thompson AJ, Bowden S, Croagh C,
Bell S, Desmond PV, Levy M and Locarnini SA: Hepatitis B surface
antigen levels during the natural history of chronic hepatitis B: A
perspective on Asia. J Hepatol. 52:508–513. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Thompson AJ, Nguyen T, Iser D, Ayres A,
Jackson K, Littlejohn M, Slavin J, Bowden S, Gane EJ, Abbott W, et
al: Serum hepatitis B surface antigen and hepatitis B e antigen
titers: Disease phase influences correlation with viral load and
intrahepatic hepatitis B virus markers. Hepatology. 51:1933–1944.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Manesis EK, Papatheodoridis GV, Tiniakos
DG, Hadziyannis ES, Agelopoulou OP, Syminelaki T, Papaioannou C,
Nastos T and Karayiannis P: Hepatitis B surface antigen: Relation
to hepatitis B replication parameters in HBeAg-negative chronic
hepatitis B. J Hepatol. 55:61–68. 2011. View Article : Google Scholar
|
|
29
|
Bonilla Guerrero R and Roberts LR: The
role of hepatitis B virus integtation in the pathogenesis of human
hepatocellular carcinoma. J Hepatol. 42:760–777. 2005. View Article : Google Scholar : PubMed/NCBI
|
