|
1
|
Mirabello L, Troisi RJ and Savage SA:
Osteosarcoma incidence and survival rates from 1973 to 2004: Data
from the surveillance, epidemiology and end results program.
Cancer. 115:1531–1543. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ottaviani G and Jaffe N: The epidemiology
of osteosarcoma. Cancer Treat Res. 152:3–13. 2009. View Article : Google Scholar
|
|
3
|
Fernandez-Pineda I, Bahrami A, Green JF,
McGregor LM, Davidoff AM and Sandoval JA: Isolated subcutaneous
metastasis of osteosarcoma 5 years after initial diagnosis. J
Pediatr Surg. 46:2029–2031. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Sampo MM, Tarkkanen M, Kivioja AH,
Taskinen MH, Sankila R and Böhling TO: Osteosarcoma in Finland from
1971 through 1990: A nationwide study of epidemiology and outcome.
Acta Orthop. 79:861–866. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Osborne TS and Khanna C: A review of the
association between osteosarcoma metastasis and protein
translation. J Comp Pathol. 146:132–142. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Bernthal NM, Federman N, Eilber FR, Nelson
SD, Eckardt JJ, Eilber FC and Tap WD: Long-term results (>25
years) of a randomized, prospective clinical trial evaluating
chemotherapy in patients with high-grade, operable osteosarcoma.
Cancer. 118:5888–5893. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Jaffe N, Carrasco H, Raymond K, Ayala A
and Eftekhari F: Can cure in patients with osteosarcoma be achieved
exclusively with chemotherapy and abrogation of surgery? Cancer.
95:2202–2210. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Serra M, Scotlandi K, Manara MC, Maurici
D, Lollini PL, De Giovanni C, Toffoli G and Baldini N:
Establishment and char-acterization of multidrug-resistant human
osteosarcoma cell lines. Anticancer Res. 13:323–329.
1993.PubMed/NCBI
|
|
9
|
Li J, Zhang F and Wang S: A polysaccharide
from pomegranate peels induces the apoptosis of human osteosarcoma
cells via the mitochondrial apoptotic pathway. Tumour Biol.
35:7475–7482. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Xie X, Yin J, Jia Q, Wang J, Zou C, Brewer
KJ, Colombo C, Wang Y, Huang G and Shen J: Quercetin induces
apoptosis in the methotrexate-resistant osteosarcoma cell line
U2-OS/MTX300 via mitochondrial dysfunction and dephosphorylation of
Akt. Oncol Rep. 26:687–693. 2011.PubMed/NCBI
|
|
11
|
Zhao XH, Xu ZR, Zhang Q and Yang YM:
Simvastatin protects human osteosarcoma cells from oxidative
stress-induced apoptosis through mitochondrial-mediated signaling.
Mol Med Rep. 5:483–488. 2012.
|
|
12
|
Cao Hong, Shibayama-Imazu T, Masuda Y,
Shinki T, Nakajo S and Nakaya K: Involvement of Tiam1 in apoptosis
induced by bufalin in HeLa cells. Anticancer Res. 27:245–249.
2007.
|
|
13
|
Dong Y, Yin S, Li J, Jiang C, Ye M and Hu
H: Bufadienolide compounds sensitize human breast cancer cells to
TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway.
Apoptosis. 16:394–403. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Gu W, Liu L, Fang FF, Huang F, Cheng BB
and Li B: Reversal effect of bufalin on multidrug resistance in
human hepatocellular carcinoma BEL-7402/5-FU cells. Oncol Rep.
31:216–222. 2014.
|
|
15
|
Hu F, Han J, Zhai B, Ming X, Zhuang L, Liu
Y, Pan S and Liu T: Blocking autophagy enhances the apoptosis
effect of bufalin on human hepatocellular carcinoma cells through
endoplasmic reticulum stress and JNK activation. Apoptosis.
19:210–223. 2014. View Article : Google Scholar
|
|
16
|
Kurosawa M, Tani Y, Nishimura S, Numazawa
S and Yoshida T: Distinct PKC isozymes regulate bufalin-induced
differentiation and apoptosis in human monocytic cells. Am J
Physiol Cell Physiol. 280:C459–464. 2001.PubMed/NCBI
|
|
17
|
Yin PH, Liu X, Qiu YY, Cai JF, Qin JM, Zhu
HR and Li Q: Anti-tumor activity and apoptosis-regulation
mechanisms of bufalin in various cancers: New hope for cancer
patients. Asian Pac J Cancer Prev. 13:5339–5343. 2012. View Article : Google Scholar
|
|
18
|
Zhu Z, Li E and Liu Y, Gao Y, Sun H, Wang
Y, Wang Z, Liu X, Wang Q and Liu Y: Bufalin induces the apoptosis
of acute promyelocytic leukemia cells via the downregulation of
survivin expression. Acta Haematol. 128:144–150. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhu Z, Sun H, Ma G, Wang Z, Li E and Liu Y
and Liu Y: Bufalin induces lung cancer cell apoptosis via the
inhibition of pi3k/akt pathway. Int J Mol Sci. 13:2025–2035. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chang Y, Zhao Y, Zhan H, Wei X, Liu T and
Zheng B: Bufalin inhibits the differentiation and proliferation of
human osteosarcoma cell line hMG63-derived cancer stem cells.
Tumour Biol. 35:1075–1082. 2014. View Article : Google Scholar
|
|
21
|
Wang D and Bi Z: Bufalin inhibited the
growth of human osteo-sarcoma MG-63 cells via down-regulation of
Bcl-2/Bax and triggering of the mitochondrial pathway. Tumour Biol.
35:4885–4890. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Arora S and Tandon S: Achyranthes aspera
root extracts induce human colon cancer cell (colo-205) death by
triggering the mitochondrial apoptosis pathway and s phase cell
cycle arrest. Scientific World Journal. 2014:1296972014. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kluck RM, Bossy-Wetzel E, Green DR and
Newmeyer DD: The release of cytochrome c from mitochondria: A
primary site for Bcl-2 regulation of apoptosis. Science.
275:1132–1136. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Li G, Miskimen KL, Wang Z, Xie XY,
Brenzovich J, Ryan JJ, Tse W, Moriggl R and Bunting KD: STAT5
requires the N-domain for suppression of miR15/16, induction of
bcl-2 and survival signaling in myeloproliferative disease. Blood.
115:1416–1424. 2010. View Article : Google Scholar :
|
|
25
|
Shimizu S, Takehara T, Hikita H, Kodama T,
Miyagi T, Hosui A, Tatsumi T, Ishida H, Noda T and Nagano H: The
let-7 family of microRNAs inhibits Bcl-xL expression and
potentiates sorafenib-induced apoptosis in human hepatocellular
carcinoma. J Hepatol. 52:698–704. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Zhang LS, Nakaya K, Yoshida T and Kuroiwa
Y: Bufalin as a potent inducer of differentiation of human myeloid
leukemia cells. Biochemical and biophysical research
communications. 178:686–693. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Krenn L and Kopp B: Bufadienolides from
animal and plant sources. Phytochemistry. 48:1–29. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Sun L, Chen T, Wang X, Chen Y and Wei X:
Bufalin induces reactive oxygen species dependent bax translocation
and apoptosis in astc-a-1 cells. Evid Based Complement Alternat
Med. 2011:2490902011. View Article : Google Scholar :
|
|
29
|
Masuda Y, Kawazoe N, Nakajo S, Yoshida T,
Kuroiwa Y and Nakaya K: Bufalin induces apoptosis and influences
the expression of apoptosis-related genes in human leukemia cells.
Leuk Res. 19:549–556. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yu CH, Kan SF, Pu HF, Jea Chien E and Wang
PS: Apoptotic signaling in bufalin- and cinobufagin-treated
androgen-dependent and -independent human prostate cancer cells.
Cancer Sci. 99:2467–2476. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Naranmandura H, Chen X, Tanaka M, Wang WW,
Rehman K, Xu S, Chen Z, Chen SQ and Suzuki N: Release of apoptotic
cytochrome C from mitochondria by dimethylarsinous acid occurs
through interaction with voltage-dependent anion channel in vitro.
Toxicol Sci. 128:137–146. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Ola MS, Nawaz M and Ahsan H: Role of Bcl-2
family proteins and caspases in the regulation of apoptosis. Mol
Cell Biochem. 351:41–58. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Edlich F, Banerjee S, Suzuki M, Cleland
MM, Arnoult D, Wang C, Neutzner A, Tjandra N and Youle RJ: Bcl-x(L)
retrotranslocates Bax from the mitochondria into the cytosol. Cell.
145:104–116. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Andre N, Roquelaure B and Conrath J:
Molecular effects of cyclosporine and oncogenesis: a new model.
Medical hypotheses. 63:647–652. 2004. View Article : Google Scholar : PubMed/NCBI
|
