|
1
|
Lowenfels AB and Maisonneuve P:
Epidemiology and risk factors for pancreatic cancer. Best Pract Res
Clin Gastroenterol. 20:197–209. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Thomas JK, Kim MS, Balakrishnan L,
Nanjappa V, Raju R, Marimuthu A, Radhakrishnan A, Muthusamy B, Khan
AA, Sakamuri S, et al: Pancreatic Cancer Database: An integrative
resource for pancreatic cancer. Cancer Biol Ther. 15:963–967. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Strimpakos A, Saif MW and Syrigos KN:
Pancreatic cancer: From molecular pathogenesis to targeted therapy.
Cancer Metastasis Rev. 27:495–522. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Biankin AV, Waddell N, Kassahn KS, Gingras
MC, Muthuswamy LB, Johns AL, Miller DK, Wilson PJ, Patch AM, Wu J,
et al: Pancreatic cancer genomes reveal aberrations in axon
guidance pathway genes. Nature. 491:399–405. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hingorani SR, Petricoin EF, Maitra A,
Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD,
Hitt BA, et al: Preinvasive and invasive ductal pancreatic cancer
and its early detection in the mouse. Cancer Cell. 4:437–450. 2003.
View Article : Google Scholar
|
|
6
|
Goldstein AM, Fraser MC, Struewing JP,
Hussussian CJ, Ranade K, Zametkin DP, Fontaine LS, Organic SM,
Dracopoli NC and Clark WH Jr: Increased risk of pancreatic cancer
in melanoma-prone kindreds with p16INK4 mutations. N Engl J Med.
333:970–974. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Pellegata NS, Sessa F, Renault B, Bonato
M, Leone BE, Solcia E and Ranzani GN: K-ras and p53 gene mutations
in pancreatic cancer: Ductal and nonductal tumors progress through
different genetic lesions. Cancer Res. 54:1556–1560.
1994.PubMed/NCBI
|
|
8
|
Grau AM, Zhang L, Wang W, Ruan S, Evans
DB, Abbruzzese JL, Zhang W and Chiao PJ: Induction of p21waf1
expression and growth inhibition by transforming growth factor beta
involve the tumor suppressor gene DPC4 in human pancreatic
adenocarcinoma cells. Cancer Res. 57:3929–3934. 1997.PubMed/NCBI
|
|
9
|
Sorio C, Baron A, Orlandini S, Zamboni G,
Pederzoli P, Huebner K and Scarpa A: The FHIT gene is expressed in
pancreatic ductular cells and is altered in pancreatic cancers.
Cancer Res. 59:1308–1314. 1999.PubMed/NCBI
|
|
10
|
Sarkar FH, Banerjee S and Li Y: Pancreatic
cancer: Pathogenesis, prevention and treatment. Toxicol Appl
Pharmacol. 224:326–336. 2007. View Article : Google Scholar
|
|
11
|
Luo J, Manning BD and Cantley LC:
Targeting the PI3K-Akt pathway in human cancer: Rationale and
promise. Cancer Cell. 4:257–262. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Manning BD and Cantley LC: AKT/PKB
signaling: Navigating downstream. Cell. 129:1261–1274. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Pei H, Li L, Fridley BL, Jenkins GD,
Kalari KR, Lingle W, Petersen G, Lou Z and Wang L: FKBP51 affects
cancer cell response to chemotherapy by negatively regulating Akt.
Cancer Cell. 16:259–266. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Yang D, Zhu Z, Wang W, Shen P, Wei Z, Wang
C and Cai Q: Expression profiles analysis of pancreatic cancer. Eur
Rev Med Pharmacol Sci. 17:311–317. 2013.PubMed/NCBI
|
|
15
|
Zhao LL, Zhang T, Zhuang LW, Yan BZ, Wang
RF and Liu BR: Uncovering the pathogenesis and identifying novel
targets of pancreatic cancer using bioinformatics approach. Mol
Biol Rep. 41:4697–4704. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Söderquist F, Hellström PM and Cunningham
JL: Human gastroenteropancreatic expression of melatonin and its
receptors MT1 and MT2. PLoS One. 10:e01201952015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Irizarry RA, Hobbs B, Collin F,
Beazer-Barclay YD, Antonellis KJ, Scherf U and Speed TP:
Exploration, normalization and summaries of high density
oligonucleotide array probe level data. Biostatistics. 4:249–264.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Benjamini Y and Hochberg Y: Controlling
the false discovery rate: a practical and powerful approach to
multiple testing. J R Stat Soc B. 57:289–300. 1995.
|
|
19
|
Deza MM and Deza E: Encyclopedia of
distances. Springer; Heidelberg: 2009, View Article : Google Scholar
|
|
20
|
Li M, Wu X, Wang J and Pan Y: Towards the
identification of protein complexes and functional modules by
integrating PPI network and gene expression data. BMC
Bioinformatics. 13:1092012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Szklarczyk D, Franceschini A, Kuhn M,
Simonovic M, Roth A, Minguez P, Doerks T, Stark M, Muller J, Bork
P, et al: The STRING database in 2011: Functional interaction
networks of proteins, globally integrated and scored. Nucleic Acids
Res. 39(Database issue): D561–D568. 2011. View Article : Google Scholar :
|
|
22
|
Shannon P, Markiel A, Ozier O, Baliga NS,
Wang JT, Ramage D, Amin N, Schwikowski B and Ideker T: Cytoscape: A
software environment for integrated models of biomolecular
interaction networks. Genome Res. 13:2498–2504. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Hulsegge I, Kommadath A and Smits MA:
Globaltest and GOEAST: Two different approaches for Gene Ontology
analysis. BMC Proc. 3(Suppl 4): S102009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Huang da W, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nat Protoc. 4:44–57. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kanehisa M and Goto S: KEGG: Kyoto
encyclopedia of genes and genomes. Nucleic Acids Res. 28:27–30.
2000. View Article : Google Scholar
|
|
26
|
MacDonald JR, Ziman R, Yuen RK, Feuk L and
Scherer SW: The Database of Genomic Variants: A curated collection
of structural variation in the human genome. Nucleic Acids Res.
42(Database issue): D986–D992. 2014. View Article : Google Scholar :
|
|
27
|
Xu H, Poh WT, Sim X, Ong RT, Suo C, Tay
WT, Khor CC, Seielstad M, Liu J, Aung T, et al: SgD-CNV, a database
for common and rare copy number variants in three Asian
populations. Hum Mutat. 32:1341–1349. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Shaikh TH, Gai X, Perin JC, Glessner JT,
Xie H, Murphy K, O'Hara R, Casalunovo T, Conlin LK, D'Arcy M, et
al: High-resolution mapping and analysis of copy number variations
in the human genome: a data resource for clinical and research
applications. Genome Res. 19:1682–1690. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Wong KK, deLeeuw RJ, Dosanjh NS, Kimm LR,
Cheng Z, Horsman DE, MacAulay C, Ng RT, Brown CJ, Eichler EE and
Lam WL: A comprehensive analysis of common copy-number variations
in the human genome. Am J Hum Genet. 80:91–104. 2007. View Article : Google Scholar :
|
|
30
|
Abecasis GR, Auton A, Brooks LD, Durbin
RM, Garrison EP, Kang HM, Korbel JO, Marchini JL, McCarthy S,
McVean GA and Abecasis GR: 1000 Genomes Project Consortium: An
integrated map of genetic variation from 1,092 human genomes.
Nature. 491:56–65. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
McKernan KJ, Peckham HE, Costa GL,
McLaughlin SF, Fu Y, Tsung EF, Clouser CR, Duncan C, Ichikawa JK,
Lee CC, et al: Sequence and structural variation in a human genome
uncovered by short-read, massively parallel ligation sequencing
using two-base encoding. Genome Res. 19:1527–1541. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Conrad DF, Pinto D, Redon R, Feuk L,
Gokcumen O, Zhang Y, Aerts J, Andrews TD, Barnes C, Campbell P, et
al: Origins and functional impact of copy number variation in the
human genome. Nature. 464:704–712. 2010. View Article : Google Scholar
|
|
33
|
Mills RE, Luttig CT, Larkins CE, Beauchamp
A, Tsui C, Pittard WS and Devine SE: An initial map of insertion
and deletion (INDEL) variation in the human genome. Genome Res.
16:1182–1190. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Kim JI, Ju YS, Park H, Kim S, Lee S, Yi
JH, Mudge J, Miller NA, Hong D, Bell CJ, et al: A highly annotated
whole-genome sequence of a Korean individual. Nature.
460:1011–1015. 2009.PubMed/NCBI
|
|
35
|
Hruban RH, Adsay NV, Albores-Saavedra J,
Compton C, Garrett ES, Goodman SN, Kern SE, Klimstra DS, Klöppel G,
Longnecker DS, et al: v Am J Surg Pathol. 25:579–586. 2001.
View Article : Google Scholar
|
|
36
|
Feuk L, Carson AR and Scherer SW:
Structural variation in the human genome. Nat Rev Genet. 7:85–97.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Redon R, Ishikawa S, Fitch KR, Feuk L,
Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, et
al: Global variation in copy number in the human genome. Nature.
444:444–454. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Ardito CM, Grüner BM, Takeuchi KK,
Lubeseder-Martellato C, Teichmann N, Mazur PK, DelGiorno KE,
Carpenter ES, Halbrook CJ, Hall JC, et al: EGF receptor is required
for KRAS-induced pancreatic tumorigenesis. Cancer Cell. 22:304–317.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Barton CM, Hall PA, Hughes CM, Gullick WJ
and Lemoine NR: Transforming growth factor alpha and epidermal
growth factor in human pancreatic cancer. J Pathol. 163:111–116.
1991. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Sennino B, Ishiguro-Oonuma T, Wei Y,
Naylor RM, Williamson CW, Bhagwandin V, Tabruyn SP, You WK, Chapman
HA, Christensen JG, et al: Suppression of tumor invasion and
metastasis by concurrent inhibition of c-Met and VEGF signaling in
pancreatic neuroendocrine tumors. Cancer Discov. 2:270–287. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Pasche B, Pennison MJ, Jimenez H and Wang
M: TGFBR1 and cancer susceptibility. Trans Am Clin Climatol Assoc.
125:300–312. 2014.PubMed/NCBI
|
|
42
|
McCarroll SA, Hadnott TN, Perry GH, Sabeti
PC, Zody MC, Barrett JC, Dallaire S, Gabriel SB, Lee C, Daly MJ, et
al: Common deletion polymorphisms in the human genome. Nat Genet.
38:86–92. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
43
|
Nguyen DQ, Webber C and Ponting CP: Bias
of selection on human copy-number variants. PLoS Genet. 2:e202006.
View Article : Google Scholar : PubMed/NCBI
|
