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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2016 Volume 13 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review)

Kuo Yan, Li‑Na Gao, Yuan‑Lu Cui, Yi Zhang, Xin Zhou
Pages: 3715-3723
Published online on: 18 March 2016

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Article Open Access

Temporal profiles of blood pressure, circulating nitric oxide, and adrenomedullin as predictors of clinical outcome in acute ischemic stroke patients

Marta Serrano‑Ponz, Carmen Rodrigo‑Gasqué, Eva Siles, Esther Martínez‑Lara, Laura Ochoa‑Callejero, Alfredo Martínez
Pages: 3724-3734
Published online on: 18 March 2016

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Article Open Access

Whole-genome re-sequencing for the identification of high contribution susceptibility gene variants in patients with type 2 diabetes

Xiaojuan Sun, Weiguo Sui, Xiaobing Wang, Xianliang Hou, Minglin Ou, Yong Dai, Yueying Xiang
Pages: 3735-3746
Published online on: 18 March 2016

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Article Open Access

Osteo-/odontogenic differentiation of BMP2 and VEGF gene-co-transfected human stem cells from apical papilla

Wen Zhang, Xiaolei Zhang, Junqi Ling, Xi Wei, Yutao Jian
Pages: 3747-3754
Published online on: 16 March 2016

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Article Open Access

Mesenchymal stem cells ameliorate inflammatory cytokine-induced impairment of AT-II cells through a keratinocyte growth factor-dependent PI3K/Akt/mTOR signaling pathway

Jiwei Li, Sha Huang, Junhua Zhang, Changjiang Feng, Dongyun Gao, Bin Yao, Xu Wu, Xiaobing Fu
Pages: 3755-3762
Published online on: 18 March 2016

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Article Open Access

Curcumin induces G2/M arrest and triggers apoptosis via FoxO1 signaling in U87 human glioma cells

Chao Cheng, Jian‑Tong Jiao, Yu Qian, Xiao‑Yi Guo, Jin Huang, Min‑Chao Dai, Lei Zhang, Xiao‑Peng Ding, Da Zong, Jun‑Fei Shao
Pages: 3763-3770
Published online on: 21 March 2016

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Article Open Access

Inhibition of mTOR signaling protects photoreceptor cells against serum deprivation by reducing oxidative stress and inducing G2/M cell cycle arrest

Bin Fan, Fu‑Qaing Li, Jing‑Yao Song, Xu Chen, Guang‑Yu Li
Pages: 3771-3778
Published online on: 18 March 2016

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Article Open Access

Screening for genes and subnetworks associated with pancreatic cancer based on the gene expression profile

Jin Long, Zhe Liu, Xingda Wu, Yuanhong Xu, Chunlin Ge
Pages: 3779-3786
Published online on: 18 March 2016

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Article Open Access

Farnesyl pyrophosphate synthase inhibitor, ibandronate, improves endothelial function in spontaneously hypertensive rats

Jie Han, Dong‑Mei Jiang, Yang Ye, Chang‑Qing Du, Jian Yang, Shen‑Jiang Hu
Pages: 3787-3796
Published online on: 21 March 2016

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Profiling lethal factor interacting proteins from human stomach using T7 phage display screening

Albin Cardona‑Correa, Carlos Rios‑Velazquez
Pages: 3797-3804
Published online on: 21 March 2016

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Article Open Access

Fibulin-3 may improve vascular health through inhibition of MMP-2/9 and oxidative stress in spontaneously hypertensive rats

Zhongwei Lin, Zhuo Wang, Guobiao Li, Bowei Li, Wenlin Xie, Dingcheng Xiang
Pages: 3805-3812
Published online on: 21 March 2016

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Article Open Access

GGsTOP increases migration of human periodontal ligament cells in vitro via reactive oxygen species pathway

Ying Jiang, Xiang Wang, Ying Li, Sen Mu, Shuang Zhou, Yi Liu, Bin Zhang
Pages: 3813-3820
Published online on: 21 March 2016

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Article Open Access

Hypoxia is important in F‑18 FDG accumulation in thecoma‑fibroma tumors on F‑18 FDG PET/CT scans

Hiroko Seino, Shuichi Ono, Hiroyuki Miura, Satoko Morohashi, Yunyan Wu, Fumiyasu Tsushima, Yoshihiro Takai, Hiroshi Kijima
Pages: 3821-3827
Published online on: 21 March 2016

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Article Open Access

Expression of MIF and c-erbB-2 in endometrial cancer

Wei Xiao, Xiujuan Dong, Honghui Zhao, Shiyu Han, Ruixue Nie, Xiahua Zhang, Ruifang An
Pages: 3828-3834
Published online on: 16 March 2016

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Article Open Access

Inhibition of the translocation and extracellular release of high-mobility group box 1 alleviates liver damage in fibrotic mice in response to D-galactosamine/lipopolysaccharide challenge

Li Bai, Ming Kong, Qingfen Zheng, Xiaohui Zhang, Xin Liu, Kejia Zu, Yu Chen, Sujun Zheng, Junfeng Li, Feng Ren, Jinli Lou, Shuang Liu, Zhongping Duan
Pages: 3835-3841
Published online on: 18 March 2016

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Article Open Access

The ‘selfish brain’ is regulated by aquaporins and autophagy under nutrient deprivation

Qiao Ye, Yonghong Wu, Yan Gao, Zhihui Li, Weiguang Li, Chenggang Zhang
Pages: 3842-3848
Published online on: 11 March 2016

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Article Open Access

Co-culture with podoplanin+ cells protects leukemic blast cells with leukemia-associated antigens in the tumor microenvironment

Ji Yoon Lee, A‑Reum Han, Sung‑Eun Lee, Woo‑Sung Min, Hee‑Je Kim
Pages: 3849-3857
Published online on: 18 March 2016

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Article Open Access

Knockdown of ANXA1 suppresses the biological behavior of human NSCLC cells in vitro

Ying Fang, Xiaoying Guan, Tonghui Cai, Jie Long, Hongyan Wang, Xiaobin Xie, Yajie Zhang
Pages: 3858-3866
Published online on: 21 March 2016

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Article Open Access

S-Adenosylmethionine suppresses the expression of Smad3/4 in activated human hepatic stellate cells via Rac1 promoter methylation

Kangqi Bian, Feng Zhang, Tingting Wang, Xiaoping Zou, Xuhong Duan, Guangxia Chen, Yuzheng Zhuge
Pages: 3867-3873
Published online on: 17 March 2016

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Article Open Access

Altered function of monocytes/macrophages in patients with autoimmune hepatitis

Rui Lin, Jie Zhang, Lu Zhou, Bangmao Wang
Pages: 3874-3880
Published online on: 17 March 2016

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Article Open Access

Cathelicidin-related antimicrobial peptide modulates the severity of acute pancreatitis in mice

Yuan‑Yuan Deng, Muhammad Shamoon, Yue He, Madhav Bhatia, Jia Sun
Pages: 3881-3885
Published online on: 18 March 2016

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Article Open Access

IL‑6 and IL‑8 enhance factor H binding to the cell membranes

Sylwia Popek, Lucyna Kapka‑Skrzypczak, Krzysztof Sawicki, Ewa Wolińska, Maciej Skrzypczak, Magdalena Czajka
Pages: 3886-3894
Published online on: 18 March 2016

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Article Open Access

Antiadipogenic effects of subthermal electric stimulation at 448 kHz on differentiating human mesenchymal stem cells

María Luisa Hernández‑Bule, Javier Martínez‑Botas, María Ángeles Trillo, Carlos L Paíno, Alejandro Úbeda
Pages: 3895-3903
Published online on: 21 March 2016

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Article Open Access

Translational informatics approach for identifying the functional molecular communicators linking coronary artery disease, infection and inflammation

Ankit Sharma, Madankumar Ghatge, Lakshmi Mundkur, Rajani Kanth Vangala
Pages: 3904-3912
Published online on: 18 March 2016

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Article Open Access

Gene expression profile analysis of pancreatic cancer based on microarray data

Jin Long, Zhe Liu, Xingda Wu, Yuanhong Xu, Chunlin Ge
Pages: 3913-3919
Published online on: 21 March 2016

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Article Open Access

Transcription factor‑microRNA synergistic regulatory network revealing the mechanism of polycystic ovary syndrome

Hai‑Ying Liu, Yu‑Ling Huang, Jian‑Qiao Liu, Qing Huang
Pages: 3920-3928
Published online on: 21 March 2016

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Article

MicroRNA-200b inhibits the proliferation of hepatocellular carcinoma by targeting DNA methyltransferase 3a

Xing‑Yu Li, Xing‑Zi Feng, Jian‑Zhong Tang, Kun Dong, Jun‑Feng Wang, Chun‑Cheng Meng, Jun Wang, Yi‑Wo Mo, Zhi‑Wei Sun
Pages: 3929-3935
Published online on: 16 March 2016

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Article

Melatonin attenuates hLRRK2-induced sleep disturbances and synaptic dysfunction in a Drosophila model of Parkinson's disease

Xicui Sun, Dongzhi Ran, Xiaofeng Zhao, Yi Huang, Simei Long, Fengyin Liang, Wenyuan Guo, Frederick C. Nucifora, Huaiyu Gu, Xilin Lu, Ling Chen, Jinsheng Zeng, Christopher A. Ross, Zhong Pei
Pages: 3936-3944
Published online on: 16 March 2016

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Article

Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells

Esam M. Radwan, Rasedee Abdullah, Mothanna Sadiq Al‑Qubaisi, Mohamed E. El Zowalaty, Seïf‑Eddine Naadja, Noorjahan B. Alitheen, Abdul‑Rahman Omar
Pages: 3945-3952
Published online on: 16 March 2016

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Article

Protective effect of berberine on doxorubicin‑induced acute hepatorenal toxicity in rats

Xueyan Chen, Yu Zhang, Zhongning Zhu, Huanlong Liu, Huicai Guo, Chen Xiong, Kerang Xie, Xiaofei Zhang, Suwen Su
Pages: 3953-3960
Published online on: 21 March 2016

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Article

Expression of trophinin and dipeptidyl peptidase IV in endometrial co-culture in the presence of an embryo: A comparative immunocytochemical study

Elif Gelenli Dolanbay, Melda Yardimoglu, Ender Yalcinkaya, Yusufhan Yazir, Ayca Aksoy, Erdal Karaoz, Eray Caliskan
Pages: 3961-3968
Published online on: 21 March 2016

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Article

PageRank analysis reveals topologically expressed genes correspond to psoriasis and their functions are associated with apoptosis resistance

Xue Zeng, Jingjing Zhao, Xiaohong Wu, Hongbo Shi, Wali Liu, Bingnan Cui, Li Yang, Xu Ding, Ping Song
Pages: 3969-3976
Published online on: 18 March 2016

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Article

CGRP may regulate bone metabolism through stimulating osteoblast differentiation and inhibiting osteoclast formation

Haitao He, Jianshen Chai, Shengfu Zhang, Linlin Ding, Peng Yan, Wenjun Du, Zhenzhou Yang
Pages: 3977-3984
Published online on: 21 March 2016

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Article

Studies on the purification of polysaccharides separated from Tremella fuciformis and their neuroprotective effect

Yaxiang Jin, Xinyu Hu, Yan Zhang, Tianji Liu
Pages: 3985-3992
Published online on: 21 March 2016

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Article

Lazaroid U83836E protects the heart against ischemia reperfusion injury via inhibition of oxidative stress and activation of PKC

Li‑Na Lai, Xiao‑Jing Zhang, Xiao‑Yi Zhang, Li‑Hua Song, Chun‑Hua Guo, Jing‑Wen Lei, Xiao‑Liang Song
Pages: 3993-4000
Published online on: 21 March 2016

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Article

p38 mitogen-activated protein kinase inhibition modulates nucleus pulposus cell apoptosis in spontaneous resorption of herniated intervertebral discs: An experimental study in rats

Yu Zhu, Jin‑Tao Liu, Li‑Yan Yang, Wen‑Pei Du, Xiao‑Chun Li, Xiang Qian, Peng‑Fei Yu, Jian‑Wen Liu, Hong Jiang
Pages: 4001-4006
Published online on: 22 March 2016

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Article

Anthocyanins inhibit trastuzumab-resistant breast cancer in vitro and in vivo

Xin Li, Jinmei Xu, Xi Tang, Yilun Liu, Xiaoping Yu, Zhi Wang, Weihua Liu
Pages: 4007-4013
Published online on: 16 March 2016

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Article

Inhibition of RANKL-induced osteoclast differentiation through the downregulation of c-Fos and NFATc1 by Eremochloa ophiuroides (centipedegrass) extract

Bo‑Yun Choi, Chul‑Hong Park, Yun Hee Na, Hyoung‑Woo Bai, Jae‑Young Cho, Byung Yeoup Chung
Pages: 4014-4022
Published online on: 18 March 2016

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Article

Sulforaphane promotes immune responses in a WEHI‑3‑induced leukemia mouse model through enhanced phagocytosis of macrophages and natural killer cell activities in vivo

Yung‑Luen Shih, Lung‑Yuan Wu, Ching‑Hsiao Lee, Yung‑Liang Chen, Shu‑Ching Hsueh, Hsu‑Feng Lu, Nien‑Chieh Liao, Jing‑Gung Chung
Pages: 4023-4029
Published online on: 21 March 2016

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Article

miR‑19a‑3p targets PMEPA1 and induces prostate cancer cell proliferation, migration and invasion

Sujuan Feng, Xuhui Zhu, Bohan Fan, Dawei Xie, Tao Li, Xiaodong Zhang
Pages: 4030-4038
Published online on: 21 March 2016

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Article

X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism: Identification and in vitro study of a novel small indel in the NR0B1 gene

Tingting Yu, Jian Wang, Yongguo Yu, Xiaodong Huang, Qihua Fu, Yiping Shen, Fuxiang Chen
Pages: 4039-4045
Published online on: 18 March 2016

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Article

Role of estrogen receptor in breast cancer cell gene expression

Yabing Zheng, Xiying Shao, Yuan Huang, Lei Shi, Bo Chen, Xiaojia Wang, Hongjian Yang, Zhanhong Chen, Xiping Zhang
Pages: 4046-4050
Published online on: 21 March 2016

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Article

Resveratrol attenuates inflammatory hyperalgesia by inhibiting glial activation in mice spinal cords

Lin‑Lin Wang, Dong‑Ling Shi, Hui‑Yao Gu, Ming‑Zhi Zheng, Jue Hu, Xing‑Hui Song, Yue‑Liang Shen, Ying‑Ying Chen
Pages: 4051-4057
Published online on: 21 March 2016

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Article

NAMPT protects against 6-hydroxydopamine-induced neurotoxicity in PC12 cells through modulating SIRT1 activity

Xiao‑Dong Zou, Shao‑Qing Guo, Zhi‑Wei Hu, Wei‑Lang Li
Pages: 4058-4064
Published online on: 21 March 2016

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Article

Rubus coreanus Miquel extract causes apoptosis of doxorubicin-resistant NCI/ADR-RES ovarian cancer cells via JNK phosphorylation

Min Kyoung Kim, Hyeong Sim Choi, Sung‑Gook Cho, Yong Cheol Shin, Seong‑Gyu Ko
Pages: 4065-4072
Published online on: 17 March 2016

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Article

Astaxanthin reduces isoflurane-induced neuroapoptosis via the PI3K/Akt pathway

Chun‑Mei  Wang, Xiao‑Lan  Cai, Qing‑Ping  Wen
Pages: 4073-4078
Published online on: 21 March 2016

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Article

Anticancer effect of docetaxel induces apoptosis of prostate cancer via the cofilin-1 and paxillin signaling pathway

Pan Xiao, Tianjia Ma, Chunwen Zhou, Yang Xu, Yuqiang Liu, Huaiqiang Zhang
Pages: 4079-4084
Published online on: 18 March 2016

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Article

miR‑30a‑5p in the tumorigenesis of renal cell carcinoma: A tumor suppressive microRNA

Yifan Li, Yuchi Li, Duqun Chen, Lu Jin, Zhengming Su, Jiaju Liu, Hongfang Duan, Xiaoqing Li, Zhengyu Qi, Min Shi, Liangchao Ni, Shangqi Yang, Yaoting Gui, Xiangming Mao, Yun Chen, Yongqing Lai
Pages: 4085-4094
Published online on: 21 March 2016

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Article

rs621554 single nucleotide polymorphism of DLC1 is associated with breast cancer susceptibility and prognosis

Xia Ding, Sumei Gao, Qifeng Yang
Pages: 4095-4100
Published online on: 08 March 2016

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Article

MicroRNA-21 modulates radiation resistance through upregulation of hypoxia-inducible factor-1α-promoted glycolysis in non-small cell lung cancer cells

Shumei Jiang, Renben Wang, Hongjiang Yan, Linzhi Jin, Xue Dou, Dong Chen
Pages: 4101-4107
Published online on: 18 March 2016

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Article

MicroRNA-335-5p inhibits osteoblast apoptosis induced by high glucose

Jiling Li, Zhengping Feng, Lixue Chen, Xiaoju Wang, Huacong Deng
Pages: 4108-4112
Published online on: 16 March 2016

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Article

Characteristics of B cell‑associated gene expression in patients with coronary artery disease

Wenwen Yan, Haoming Song, Jinfa Jiang, Wenjun Xu, Zhu Gong, Qianglin Duan, Chuangrong Li, Yuan Xie, Lemin Wang
Pages: 4113-4121
Published online on: 21 March 2016

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Article

Vagus nerve electrical stimulation inhibits serum levels of S100A8 protein in septic shock rats

Ming Lei, Xin‑Xin Liu
Pages: 4122-4128
Published online on: 18 March 2016

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Article Open Access

Effects of NOX1 on fibroblastic changes of endothelial cells in radiation‑induced pulmonary fibrosis

Seo‑Hyun Choi, Miseon Kim, Hae‑June Lee, Eun‑Ho Kim, Chun‑Ho Kim, Yoon‑Jin Lee
Pages: 4135-4142
Published online on: 05 April 2016

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Article Open Access

Correlation between insulin‑like growth factor binding protein 3 and metastasis‑associated gene 1 protein in esophageal squamous cell carcinoma

Haiping Yang, Lijuan Xu, Haili Qian, Xinqiang Niu, Dan Zhao, Zhilong Zhao, Jun Wu, Junfeng Liu, Yanyu Wang
Pages: 4143-4150
Published online on: 28 March 2016

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Article Open Access

Differential expression of EBV proteins LMP1 and BHFR1 in EBV‑associated gastric and nasopharyngeal cancer tissues

Ailiang Wang, Wei Zhang, Meng Jin, Jianbo Zhang, Sheng Li, Feng Tong, Yanbing Zhou
Pages: 4151-4158
Published online on: 05 April 2016

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Article Open Access

Inhibition of histone deacetylases by trans-cinnamic acid and its antitumor effect against colon cancer xenografts in athymic mice

Bingyan Zhu, Boyang Shang, Yi Li, Yongsu Zhen
Pages: 4159-4166
Published online on: 23 March 2016

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Article Open Access

Extracts of Bauhinia championii (Benth.) Benth. attenuate the inflammatory response in a rat model of collagen-induced arthritis

Wei Xu, Mingqing Huang, Yuqin Zhang, Huang Li, Haiyin Zheng, Lishuang Yu, Kedan Chu, Yu Lin, Lidian Chen
Pages: 4167-4174
Published online on: 30 March 2016

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Article Open Access

Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling

Rong Yang, Liang Zhong, Xiao‑Qun Yang, Kai‑Ling Jiang, Liu Li, Hao Song, Bei‑Zhong Liu
Pages: 4175-4182
Published online on: 28 March 2016

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Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model

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Ameliorating effect of luteolin on memory impairment in an Alzheimer's disease model

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MicroRNA-29b inhibits TGF-β1-induced fibrosis via regulation of the TGF-β1/Smad pathway in primary human endometrial stromal cells

Jingxiong Li, Bohong Cen, Siping Chen, Yuanli He
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Attenuation of liver fibrosis by herbal compound 861 via upregulation of BMP-7/Smad signaling in the bile duct ligation model rat

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Effect of growth differentiation factor‑9 C447T and G546A polymorphisms on the outcomes of in vitro fertilization

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Time-dependent activity of Na+/H+ exchanger isoform 1 and homeostasis of intracellular pH in astrocytes exposed to CoCl2 treatment

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Artemisinin inhibits gallbladder cancer cell lines through triggering cell cycle arrest and apoptosis

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Knockdown of LI-cadherin alters expression of matrix metalloproteinase-2 and -9 and galectin-3

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Piperlongumine inhibits gastric cancer cells via suppression of the JAK1,2/STAT3 signaling pathway

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Upregulation of long non coding RNA PCAT-1 contributes to cell proliferation, migration and apoptosis in hepatocellular carcinoma

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Maternal undernutrition leads to elevated hepatic triglycerides in male rat offspring due to increased expression of lipoprotein lipase

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Tumor-promoting function of single nucleotide polymorphism rs1836724 (C3388T) alters multiple potential legitimate microRNA binding sites at the 3'-untranslated region of ErbB4 in breast cancer

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miR‑140‑5p regulates angiogenesis following ischemic stroke by targeting VEGFA

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3-Deoxyglucosone induces insulin resistance by impairing insulin signaling in HepG2 cells

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A comparative study of the timecourse of the expression of the thermo‑inducible HSP70 gene in clinical and environmental isolates of Aspergillus fumigatus

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
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Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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