|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bosch FX, Ribes J, Díaz M and Cléries R:
Primary liver cancer: Worldwide incidence and trends.
Gastroenterology. 127(5 Suppl 1): S5–S16. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Finn RS: Development of molecularly
targeted therapies in hepatocellular carcinoma: Where do we go now?
Clin Cancer Res. 16:390–397. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Collier FM, Gregorio-King CC, Gough TJ,
Talbot CD, Walder K and Kirkland MA: Identification and
characterization of a lymphocytic Rho-GTPase effector: Rhotekin-2.
Biochem Biophys Res Commun. 324:1360–1369. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Reid T, Furuyashiki T, Ishizaki T,
Watanabe G, Watanabe N, Fujisawa K, Morii N, Madaule P and Narumiya
S: Rhotekin, a new putative target for Rho bearing homology to a
serine/threonine kinase, PKN and rhophilin in the rho-binding
domain. J Biol Chem. 271:13556–13560. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Karlsson R, Pedersen ED, Wang Z and
Brakebusch C: Rho GTPase function in tumorigenesis. Biochim Biophys
Acta. 1796:91–98. 2009.PubMed/NCBI
|
|
7
|
Liu CA, Wang MJ, Chi CW, Wu CW and Chen
JY: Rho/Rhotekin-mediated NF-kappaB activation confers resistance
to apoptosis. Oncogene. 23:8731–8742. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Liu CA, Wang MJ, Chi CW, Wu CW and Chen
JY: Overexpression of rho effector rhotekin confers increased
survival in gastric adenocarcinoma. J Biomed Sci. 11:661–670. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Collier FM, Baker AJ, Walder K, Stupka N,
Martin SD and Kirkland MA: A Rho-GTPase effector, rhotekin-2
(RTKN2) is associated with BMP8b and IL-16 cytokine expression anti
increased sensitivity to apoptosis in lymphocytes. Blood amer soc
hematology 1900 M street. NW suite 200, Washington, DC 20036 USA:
pp. 679A–680A. 2007
|
|
10
|
Collier FM, Loving A, Baker AJ, McLeod J,
Walder K and Kirkland MA: RTKN2 induces NF-KappaB dependent
resistance to intrinsic apoptosis in HEK cells and regulates BCL-2
genes in human CD4(+) lymphocytes. J Cell Death. 2:9–23.
2009.PubMed/NCBI
|
|
11
|
Li W, Wu YF, Xu RH, Lu H, Hu C and Qian H:
miR-1246 releases RTKN2-dependent resistance to UVB-induced
apoptosis in HaCaT cells. Mol Cell Biochem. 394:299–306. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gregorio-King CC, Gough T, Van Der Meer
GJ, Hosking JB, Waugh CM, McLeod JL, Collier FM and Kirkland MA:
Mechanisms of resistance to the cytotoxic effects of oxysterols in
human leukemic cells. J Steroid Biochem Mol Biol. 88:311–320. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Saha SK, Roy S and Khuda-Bukhsh AR:
Ultra-highly diluted plant extracts of Hydrastis canadensis and
Marsdenia condurango induce epigenetic modifications and alter gene
expression profiles in HeLa cells in vitro. J Integr Med.
13:400–411. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Papavasiliou FN and Schatz DG:
Cell-cycle-regulated DNA double-strand breaks in somatic
hypermutation of immunoglobulin genes. Nature. 408:216–221. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Ye G, Qin Y, Lu X, Xu X, Xu S, Wu C, Wang
X, Wang S and Pan D: The association of renin-angiotensin system
genes with the progression of hepatocellular carcinoma. Biochem
Biophys Res Commun. 459:18–23. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kubben FJ, Peeters-Haesevoets A, Engels
LG, Baeten CG, Schutte B, Arends JW, Stockbrügger RW and Blijham
GH: Proliferating cell nuclear antigen (PCNA): A new marker to
study human colonic cell proliferation. Gut. 35:530–535. 1994.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ferrell JE Jr, Wu M, Gerhart JC and Martin
GS: Cell cycle tyrosine phosphorylation of p34cdc2 and a
microtubule-associated protein kinase homolog in Xenopus oocytes
and eggs. Mol Cell Biol. 11:1965–1971. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wong CC, Wong CM, Au SL and Ng IO:
RhoGTPases and Rho-effectors in hepatocellular carcinoma
metastasis: ROCK N'Rho move it. Liver Int. 30:642–656. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Grise F, Bidaud A and Moreau V: Rho
GTPases in hepatocellular carcinoma. Biochim Biophys Acta.
1795:137–151. 2009.PubMed/NCBI
|
|
20
|
Leber MF and Efferth T: Molecular
principles of cancer invasion and metastasis (review). Int J Oncol.
34:881–895. 2009.PubMed/NCBI
|
