Taraxacum coreanum protects against glutamate-induced neurotoxicity through heme oxygenase-1 expression in mouse hippocampal HT22 cells

Uttara B, Singh AV, Zamboni P and Mahajan RT: Oxidative stress and neurodegenerative diseases: A review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol. 7:65–74. 2009. View Article : Google Scholar : PubMed/NCBI

Schubert D and Piasecki D: Oxidative glutamate toxicity can be a component of the excitotoxicity cascade. J Neurosci. 21:7455–7462. 2001.PubMed/NCBI

Davis JB and Maher P: Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell lines. Brain Res. 652:169–173. 1994. View Article : Google Scholar : PubMed/NCBI

Murphy TH, Miyamoto M, Sastre A, Schnaar RL and Coyle JT: Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron. 2:1547–1558. 1989. View Article : Google Scholar : PubMed/NCBI

Rössler OG, Bauer I, Chung HY and Thiel G: Glutamate-induced cell death of immortalized murine hippocampal neurons: Neuroprotective activity of heme oxygenase-1, heat shock protein 70 and sodium selenite. Neurosci Lett. 362:253–257. 2004. View Article : Google Scholar : PubMed/NCBI

Cabell L, Ferguson C, Luginbill D, Kern M, Weingart A and Audesirk G: Differential induction of heme oxygenase and other stress proteins in cultured hippocampal astrocytes and neurons by inorganic lead. Toxicol Appl Pharmacol. 198:49–60. 2004. View Article : Google Scholar : PubMed/NCBI

Satoh T, Baba M, Nakatsuka D, Ishikawa Y, Aburatani H, Furuta K, Ishikawa T, Hatanaka H, Suzuki M and Watanabe Y: Role of heme oxygenase-1 protein in the neuroprotective effects of cyclopentenone prostaglandin derivatives under oxidative stress. Eur J Neurosci. 17:2249–2255. 2003. View Article : Google Scholar : PubMed/NCBI

Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, et al: An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun. 236:313–322. 1997. View Article : Google Scholar : PubMed/NCBI

Ishii T, Itoh K, Takahashi S, Sato H, Yanagawa T, Katoh Y, Bannai S and Yamamoto M: Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem. 275:16023–16029. 2000. View Article : Google Scholar : PubMed/NCBI

Choi JH, Shin KM, Kim NY, Hong JP, Lee YS, Kim HJ, Park HJ and Lee KT: Taraxinic acid, a hydrolysate of sesquiterpene lactone glycoside from the Taraxacum coreanum NAKAI, induces the differentiation of human acute promyelocytic leukemia HL-60 cells. Biol Pharm Bull. 25:1446–1450. 2002. View Article : Google Scholar : PubMed/NCBI

Lee MH, Kang H, Lee K, Yang G, Ham I, Bu Y, Kim H and Choi HY: The aerial part of Taraxacum coreanum extract has an anti-inflammatory effect on peritoneal macrophages in vitro and increases survival in a mouse model of septic shock. J Ethnopharmacol. 146:1–8. 2013. View Article : Google Scholar : PubMed/NCBI

Lee DS, Ko W, Kim DC, Kim YC and Jeong GS: Cudarflavone B provides neuroprotection against glutamate-induced mouse hippocampal HT22 cell damage through the Nrf2 and PI3K/Akt signaling pathways. Molecules. 19:10818–10831. 2014. View Article : Google Scholar : PubMed/NCBI

Motterlini R, Foresti R, Intaglietta M and Winslow RM: NO-mediated activation of heme oxygenase: Endogenous cytoprotection against oxidative stress to endothelium. Am J Physiol. 270:H107–H114. 1996.PubMed/NCBI

Li XP, Yu J, Luo JY, Li HS, Han FJ, Chen XG and Hu ZD: Simultaneous determination of chlorogenic acid, caffeic acid, ferulic acid, protocatechuic acid and protocatechuic aldehyde in Chinese herbal preparation by RP-HPLC. Chem Pharm Bull. 52:1251–1254. 2004. View Article : Google Scholar : PubMed/NCBI

Ling Y, Zhang Y, Cai S, Xiao Y, Cai S and Zheng J: Chemical constituents of Taraxacum sinicum Kitag. Zhongguo Zhing Yao Za Zhi. 23:232–234. 1998.(In Chinese).

Richards AJ: Eutriploid facultative agamospermy in Taraxacum. New Phytologist. 69:761–774. 1970. View Article : Google Scholar

Farombi EO and Surh YJ: Heme oxygenase-1 as a potential therapeutic target for hepatoprotection. J Biochem Mol Biol. 39:479–491. 2006.PubMed/NCBI

Moi P, Chan K, Asunis I, Cao A and Kan YW: Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci USA. 91:9926–9930. 1994. View Article : Google Scholar : PubMed/NCBI

Qiang W, Cahill JM, Liu J, Kuang X, Liu N, Scofield VL, Voorhees JR, Reid AJ, Yan M, Lynn WS and Wong PK: Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes. J Virol. 78:11926–11938. 2004. View Article : Google Scholar : PubMed/NCBI