|
1
|
McCloskey SC, Patel BD, Hinchliffe SJ,
Reid ED, Wareham NJ and Lomas DA: Siblings of patients with severe
chronic obstructive pulmonary disease have significant risk of
airflow obstruction. Am J Respir Crit Care Med. 164:1419–1424.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lemjabbar-Alaoui H, Dasari V, Sidhu SS,
Mengistab A, Finkbeiner W, Gallup M and Basbaum C: Wnt and hedgehog
are critical mediators of cigarette smoke-induced lung cancer. PLoS
One. 1:e932006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Hanna A and Shevde LA: Hedgehog signaling:
Modulation of cancer properies and tumor mircroenvironment. Mol
Cancer. 15:242016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Cooper MK, Porter JA, Young KE and Beachy
PA: Teratogen-mediated inhibition of target tissue response to Shh
signaling. Science. 280:1603–1607. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kugler MC, Loomis CA, Zhao Z, Cushman JC,
Liu L and Munger JS: Sonic hedgehog signaling regulates
myofibroblast function during alveolar septum formation in murine
postnatal lung. Am J Respir Cell Mol Biol. 57:280–293. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Xu JH, Yang HP, Zhou XD, Wang HJ, Gong L
and Tang CL: Autophagy accompanied with
bisdemethoxycurcumin-induced apoptosis in non-small cell lung
cancer cells. Biomed Environ Sci. 28:105–115. 2015.PubMed/NCBI
|
|
7
|
Bermudez O, Hennen E, Koch I, Lindner M
and Eickelberg O: Gli1 mediates lung cancer cell proliferation and
sonic hedgehog-dependent mesenchymal cell activation. PLoS One.
8:e632262013. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Bao J, Ma C, Ran J, Xiong Y, Yan S and Wu
L: Wnt/β-catenin and hedgehog pathways are involved in the
inflammatory effect of interleukin 18 on rat chondrocytes.
Oncotarget. 8:109962–109972. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Beachy PA, Karhadkar SS and Berman DM:
Tissue repair and stem cell renewal in carcinogenesis. Nature.
432:324–331. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Deng M, Li J, Gan Y, Chen Y and Chen P:
Changes in the number of CD31-CD45-Sca-1+ cells and Shh signaling
pathway involvement in the lungs of mice with emphysema and
relevant effects of acute adenovirus infection. Int J Chron
Obstruct Pulmon Dis. 12:861–872. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Fu L, Wu H, Cheng SY, Gao D, Zhang L and
Zhao Y: Set7 mediated Gli3 methylation plays a positive role in the
activation of sonic hedgehog pathway in mammals. ELife.
5:e156902016. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Liu L, Kugler MC, Loomis CA, Samdani R,
Zhao Z, Chen GJ, Brandt JP, Brownell I, Joyner AL, Rom WN and
Munger JS: Hedgehog signaling in neonatal and adult lung. Am J
Respir Cell Mol Biol. 48:703–710. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Peng T, Frank DB, Kadzik RS, Morley MP,
Rathi KS, Wang T, Zhou S, Cheng L, Lu MM and Morrisey EE: Hedgehog
actively maintains adult lung quiescence and regulates repair and
regeneration. Nature. 526:578–582. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Abe Y and Tanaka N: The hedgehog signaling
networks in lung cancer: The mechanisms and roles in tumor
progression and implications for cancer therapy. Biomed Res Int.
2016:79692862016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Li R, Cai L, Ding J, Hu CM, Wu TN and Hu
XY: Inhibition of hedgehog signal pathway by cyclopamine attenuates
inflammation and articular cartilage damage in rats with
adjuvant-induced arthritis. J Pharm Pharmacol. 67:963–971. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Lao T, Jiang Z, Yun J, Qiu W, Guo F, Huang
C, Mancini JD, Gupta K, Laucho-Contreras ME, Naing ZZ, et al: Hhip
haploinsufficiency sensitizes mice to age-related emphysema. Proc
Natl Acad Sci USA. 113:E4681–E4687. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lao T, Glass K, Qiu W, Polverino F, Gupta
K, Morrow J, Mancini JD, Vuong L, Perrella MA, Hersh CP, et al:
Haploinsufficiency of hedgehog interacting protein causes increased
emphysema induced by cigarette smoke through network rewiring.
Genome Med. 7:122015. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Guo Y, Gong Y, Pan C, Qian Y, Shi G, Cheng
Q, Li Q, Ren L, Weng Q, Chen Y, et al: Association of genetic
polymorphisms with chronic obstructive pulmonary disease in the
chinese han population: A case-control study. BMC Med Genomics.
5:64–83. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Crompton T, Outram SV and
Hager-Theodorides AL: Sonic hedgehog signalling in T-cell
development and activation. Nat Rev Immunol. 7:726–735. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Merchant JL and Ding L: Hedgehog signaling
links chronic inflammation to gastric cancer precursor lesions.
Cell Mol Gastroenterol Hepatol. 3:201–210. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kakiuchi S, Minami Y, Miyata Y, Mizutani
Y, Goto H, Kawamoto S, Yakushijin K, Kurata K, Matsuoka H and
Minami H: NANOG Expression as a responsive biomarker during
treatment with hedgehog signal inhibitor in acute myeloid leukemia.
Int J Mol Sci. 18:4862017. View Article : Google Scholar :
|
