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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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June-2018 Volume 17 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Influence of the interaction between Ac‑SDKP and Ang II on the pathogenesis and development of silicotic fibrosis

Yi Zhang, Fang Yang, Yan Liu, Hai‑Bing Peng, Yu‑Cong Geng, Shi‑Feng Li, Hong Xu, Li‑Yan Zhu, Xiu‑Hong Yang, Darrell Brann
Pages: 7467-7476
Published online on: 29 March 2018

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Article Open Access

Identification of Streptococcus mitis321A vaccine antigens based on reverse vaccinology

Qiao Zhang, Kexiong Lin, Changzheng Wang, Zhi Xu, Li Yang, Qianli Ma
Pages: 7477-7486
Published online on: 28 March 2018

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Article Open Access

Ubiquitin‑like protein FAT10 regulates DNA damage repair via modification of proliferating cell nuclear antigen

Zhenchuan Chen, Wei Zhang, Zhimin Yun, Xue Zhang, Feng Gong, Yunfang Wang, Shouping Ji, Ling Leng
Pages: 7487-7496
Published online on: 05 April 2018

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Article Open Access

Pegylated liposomal‑paclitaxel induces ovarian cancer cell apoptosis via TNF‑induced ERK/AKT signaling pathway

Zhiying Qi, Lirong Yin, Yanying Xu, Fang Wang
Pages: 7497-7504
Published online on: 28 March 2018

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Article Open Access

Effect and mechanism of the aβ2‑GP I/rhβ2‑GP I complex on JEG‑3 cell proliferation, migration and invasion

Xiumin Lu, Lei Ren, Wenjing Zhang, Yanhong Liu
Pages: 7505-7512
Published online on: 29 March 2018

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Article Open Access

Curcumol attenuates epithelial-mesenchymal transition of nasopharyngeal carcinoma cells via TGF-β1

Dazhong Yan, Shishan Deng, Weigang Gan, Sijun Li, Yuanquan Li
Pages: 7513-7520
Published online on: 28 March 2018

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Article Open Access

LARP7 in papillary thyroid carcinoma induces NIS expression through suppression of the SHH signaling pathway

Xiaomei Sui, Yana Sui, Yonghui Wang
Pages: 7521-7528
Published online on: 05 April 2018

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Article Open Access

MicroRNA‑142‑5p modulates breast cancer cell proliferation and apoptosis by targeting phosphatase and tensin homolog

Wenda Xu, Weixing Wang
Pages: 7529-7536
Published online on: 28 March 2018

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Article Open Access

TRPM2 promotes the proliferation and invasion of pancreatic ductal adenocarcinoma

Rui Lin, Yufeng Wang, Quanning Chen, Zhongyan Liu, Shuai Xiao, Bingyi Wang, Baomin Shi
Pages: 7537-7544
Published online on: 28 March 2018

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Article Open Access

Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Lina Yang, Xinrui Yang, Yiwei Tang, Defu Zhang, Lijie Zhu, Shengnan Wang, Bo Wang, Tao Ma
Pages: 7545-7552
Published online on: 29 March 2018

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Article Open Access

Genetic analysis of a congenital split‑hand/split‑foot malformation 4 pedigree

Xiao Yang, Xinfu Lin, Yaobin Zhu, Jiewei Luo, Genhui Lin
Pages: 7553-7558
Published online on: 29 March 2018

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Article Open Access

Induction of Huh‑7 cell apoptosis by HCV core proteins via CK1α‑p53‑Bid signaling pathway

Shanshan Shen, Chunyang Li, Mingjia Dai, Xuebing Yan
Pages: 7559-7566
Published online on: 05 April 2018

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Article Open Access

Roseburia intestinalis inhibits interleukin‑17 excretion and promotes regulatory T cells differentiation in colitis

Changxin Zhu, Kerui Song, Zhaohua Shen, Yongsheng Quan, Bei Tan, Weiwei Luo, Shuai Wu, Kai Tang, Zhenyu Yang, Xiaoyan Wang
Pages: 7567-7574
Published online on: 29 March 2018

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Article Open Access

EGFR mutations subset in Chinese lung squamous cell carcinoma patients

Ying Sun, Xin Yin, Miao‑Miao Wen, Jiao Zhang, Xue‑Jiao Wang, Jing‑Hua Xia, Yan‑Ning Zhang, Zhi‑Pei Zhang, Xiao‑Fei Li
Pages: 7575-7584
Published online on: 05 April 2018

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Article Open Access

Identification of key genes and pathways in regulating immune‑induced diseases of dendritic cells by bioinformatic analysis

Yang Zheng, Xianghui Zheng, Shuang Li, Hanlu Zhang, Mingyang Liu, Qingyuan Yang, Maomao Zhang, Yong Sun, Jian Wu, Bo Yu
Pages: 7585-7594
Published online on: 29 March 2018

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Article Open Access

Crocin prevents platelet‑derived growth factor BB‑induced vascular smooth muscle cells proliferation and phenotypic switch

Lijian Tong, Guoxian Qi
Pages: 7595-7602
Published online on: 05 April 2018

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Article Open Access

Tenascin‑C promotes the migration of bone marrow stem cells via toll‑like receptor 4‑mediated signaling pathways: MAPK, AKT and Wnt

Huaiyu Ding, Mingyu Jin, Dai Liu, Shujing Wang, Jianing Zhang, Xiantao Song, Rongchong Huang
Pages: 7603-7610
Published online on: 05 April 2018

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Case Report Open Access

A novel missense mutation in the ACTG1 gene in a family with congenital autosomal dominant deafness: A case report

Cha Gon Lee, Jahyeon Jang, Hyun‑Seok Jin
Pages: 7611-7617
Published online on: 29 March 2018

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Article Open Access

Dynamic expression and roles of sequestome‑1/p62 in LPS‑induced acute kidney injury in mice

Ting Li, Jie Zhao, Shuying Miao, Yunfei Xu, Xianzhong Xiao, Ying Liu
Pages: 7618-7626
Published online on: 28 March 2018

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Article Open Access

TPX2 silencing mediated by joint action of microvesicles and ultrasonic radiation inhibits the migration and invasion of SKOV3 cells

Dong Huang, Jianmin Chen, Cuiyu Yang, Minzhen Wang
Pages: 7627-7635
Published online on: 28 March 2018

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Article Open Access

Integrated analysis of the gene expression profile and DNA methylation profile of obese patients with type 2 diabetes

Juan Shen, Bin Zhu
Pages: 7636-7644
Published online on: 28 March 2018

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Article Open Access

The transcription factor 7 like 2‑binding protein TIP5 activates β‑catenin/transcription factor signaling in hepatocellular carcinoma

Chushi Li, Wei Wu, Hongmei Ding, Qingyang Li, Kangkang Xie
Pages: 7645-7651
Published online on: 28 March 2018

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Article Open Access

Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF‑β1/Smad3 signaling pathway

Keyan Chen, Wei Chen, Shi Li Liu, Tian Shi Wu, Kai Feng Yu, Jing Qi, Yijun Wang, Hui Yao, Xiao Yang Huang, Ying Han, Ping Hou
Pages: 7652-7660
Published online on: 29 March 2018

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Article Open Access

Microarray expression profile analysis of circular RNAs in pancreatic cancer

Shixiang Guo, Xuejun Xu, Yongsheng Ouyang, Yunchao Wang, Jiali Yang, Liangyu Yin, Jiayun Ge, Huaizhi Wang
Pages: 7661-7671
Published online on: 29 March 2018

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Article Open Access

Role of cantharidin in the activation of IKKα/IκBα/NF‑κB pathway by inhibiting PP2A activity in cholangiocarcinoma cell lines

Huijiang Zhou, Jiangfeng Xu, Shuai Wang, Jinfeng Peng
Pages: 7672-7682
Published online on: 05 April 2018

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Article Open Access

Calotropin regulates the apoptosis of non‑small cell cancer by regulating the cytotoxic T‑lymphocyte associated antigen 4‑mediated TGF‑β/ERK signaling pathway

Lu Tian, Xiao‑Hong Xie, Ze‑Hao Zhu
Pages: 7683-7691
Published online on: 05 April 2018

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Article Open Access

Identification of the tumor‑suppressive function of circular RNA FOXO3 in non‑small cell lung cancer through sponging miR‑155

Yanni Zhang, Hui Zhao, Lichuan Zhang
Pages: 7692-7700
Published online on: 29 March 2018

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Article Open Access

Bone marrow‑derived mesenchymal stem cell‑conditioned medium attenuates tubulointerstitial fibrosis by inhibiting monocyte mobilization in an irreversible model of unilateral ureteral obstruction

Jiarong Zheng, Qinghua Wang, Weixue Leng, Xia Sun, Jun Peng
Pages: 7701-7707
Published online on: 05 April 2018

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Article Open Access

Identification of key genes in non‑alcoholic fatty liver disease progression based on bioinformatics analysis

Lin Li, Huabao Liu, Xiaoyu Hu, Yi Huang, Yanan Wang, Yansha He, Qingsong Lei
Pages: 7708-7720
Published online on: 05 April 2018

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Article Open Access

Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways

Ai‑Lei Wang, Yong Li, Qun Zhao, Li‑Qiao Fan
Pages: 7721-7729
Published online on: 05 April 2018

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Article Open Access

Isoflurane‑induced postoperative cognitive dysfunction is mediated by hypoxia‑inducible factor‑1α‑dependent neuroinflammation in aged rats

Yiyun Cao, Zhengqian Li, Lijun Ma, Cheng Ni, Lunxu Li, Ning Yang, Chengmei Shi, Xiangyang Guo
Pages: 7730-7736
Published online on: 05 April 2018

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Article Open Access

Involvement of dysregulated coding and long non‑coding RNAs in the pathogenesis of strabismus

Wen‑Xiu Ma, Xiao‑Gang Huang, Tian‑Ke Yang, Jing‑Yan Yao
Pages: 7737-7745
Published online on: 29 March 2018

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Article Open Access

Intensity‑dependent effect of treadmill running on differentiation of rat bone marrow stromal cells

Sheng‑Yao Liu, Zhe Li, Shao‑Yong Xu, Lei Xu, Mo Yang, Guo‑Xin Ni
Pages: 7746-7756
Published online on: 28 March 2018

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Article Open Access

Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models

Oana Cristina Seremet, Octavian Tudorel Olaru, Claudia Maria Gutu, George Mihai Nitulescu, Mihaela Ilie, Simona Negres, Cristina Elena Zbarcea, Carmen Nicoleta Purdel, Demetrios A. Spandidos, Aristides M. Tsatsakis, Michael D. Coleman, Denisa Marilena Margina
Pages: 7757-7763
Published online on: 26 March 2018

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Article

Granuloma formation in the liver is relatively delayed, although sustained, in BCG‑infected mice co‑infected with Plasmodium

Bayaer Nashun, Jianlan You, Musi Ji, Siting Zhao, Li Qin, Xiaoping Chen
Pages: 7764-7768
Published online on: 29 March 2018

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Article

Prohibitin and the extracellular matrix are upregulated in murine alveolar epithelial cells with LPS‑induced acute injury

Feng Zhang, Dejun Fan, Xiao‑Neng Mo
Pages: 7769-7773
Published online on: 28 March 2018

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Article

Gastrodin inhibits high glucose‑induced human retinal endothelial cell apoptosis by regulating the SIRT1/TLR4/NF‑κBp65 signaling pathway

Tong‑He Zhang, Chun‑Mei Huang, Xue Gao, Jia‑Wei Wang, Lin‑Lin Hao, Qiang Ji
Pages: 7774-7780
Published online on: 03 April 2018

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Article

lncRNAPCAT29 inhibits pulmonary fibrosis via the TGF‑β1‑regulated RASAL1/ERK1/2 signal pathway

Xiaoming Liu, Shanyu Gao, Huile Xu
Pages: 7781-7788
Published online on: 28 March 2018

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Article

MicroRNA‑148a inhibition protects against ovariectomy‑induced osteoporosis through PI3K/AKT signaling by estrogen receptor α

Yu Xiao, Bing Li, Jun Liu
Pages: 7789-7796
Published online on: 05 April 2018

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Article

Zearalenone regulates endometrial stromal cell apoptosis and migration via the promotion of mitochondrial fission by activation of the JNK/Drp1 pathway Retraction in /10.3892/mmr.2024.13363

Huixiang Wang, Xiaoli Zhao, Chengxiang Ni, Yuyang Dai, Yan Guo
Pages: 7797-7806
Published online on: 29 March 2018

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Article

A study on the correlation between STAT‑1 and mutant p53 expression in glioma

Wenbo Yang, Hongwei Wang, Haitao Ju, Changwu Dou
Pages: 7807-7812
Published online on: 28 March 2018

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Article

Hippocampal β2‑microglobulin mediates sepsis‑induced cognitive impairment

Rong Gao, Guomin Li, Runhua Yang, Hongmei Yuan, Shaogang Zhang
Pages: 7813-7820
Published online on: 05 April 2018

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Article

MicroRNA‑92a overexpression promotes the osteogenic differentiation of bone mesenchymal stem cells by impeding Smad6‑mediated runt‑related transcription factor 2 degradation

Xu Yan, Hao Wang, Yufei Li, Yuxin Jiang, Qingdong Shao, Weidong Xu
Pages: 7821-7826
Published online on: 29 March 2018

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Article

Knockdown of peroxiredoxin V increases glutamate‑induced apoptosis in HT22 hippocampal neuron cells

Gui‑Nan Shen, Lei Liu, Li Feng, Yu Jin, Mei‑Hua Jin, Ying‑Hao Han, Cheng‑Hao Jin, Yong‑Zhe Jin, Dong‑Soek Lee, Tae Ho Kwon, Yu‑Dong Cui, Hu‑Nan Sun
Pages: 7827-7834
Published online on: 29 March 2018

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Article

Phosphoinositide 3‑kinase/protein kinase B regulates inflammation severity via signaling of Toll‑like receptor 4 in severe acute pancreatitis

Jing Wang, Chun Zhang, Ping Xu, Zhi‑Wen Yang, Cheng‑Zhao Weng, Yue‑Xing Lai
Pages: 7835-7844
Published online on: 29 March 2018

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Article

Integrated analysis of long non‑coding RNA competing interactions revealed potential biomarkers in cervical cancer: Based on a public database

Wen‑Juan Wu, Yang Shen, Jing Sui, Cheng‑Yun Li, Sheng Yang, Si‑Yi Xu, Man Zhang, Li‑Hong Yin, Yue‑Pu Pu, Ge‑Yu Liang
Pages: 7845-7858
Published online on: 05 April 2018

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Article

Quercetin protects rat cortical neurons against traumatic brain injury Corrigendum in /10.3892/mmr.2022.12732

Guoliang Du, Zongmao Zhao, Yonghan Chen, Zonghao Li, Yaohui Tian, Zhifeng Liu, Bin Liu, Jianqiang Song
Pages: 7859-7865
Published online on: 28 March 2018

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Article

Puerarin regulates neovascular glaucoma through pigment epithelium‑derived growth factor‑induced NF‑κB signaling pathway

Hui‑Yu Wei, Ya‑Jie Zhang, Shao‑Zhen Zhao
Pages: 7866-7874
Published online on: 28 March 2018

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Article

EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer

Zhaomeng Wu, Qingyi Zhu, Yu Zhang, Yingying Yin, Dan Kang, Runyi Cao, Qian Tian, Shan Lu, Ping Liu
Pages: 7875-7885
Published online on: 28 March 2018

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Article

Effects of endoplasmic reticulum stress on autophagy and apoptosis of human leukemia cells via inhibition of the PI3K/AKT/mTOR signaling pathway

Li‑Juan Li, Ye Chai, Xiao‑Jia Guo, Song‑Lin Chu, Lian‑Sheng Zhang
Pages: 7886-7892
Published online on: 03 April 2018

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Article

Function of microRNA‑141 in human breast cancer through cytotoxic CD4+ T cells regulated by MAP4K4 expression

Qing Zhang, Huang Xin, Tang Fen
Pages: 7893-7901
Published online on: 28 March 2018

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Article

Differentiation of genetically modified canine bone mesenchymal stem cells labeled with superparamagnetic iron oxide into neural‑like cells

Xing‑Long Liu, Qing‑Quan Zu, Bin Wang, Shan‑Shan Lu, Xiao‑Quan Xu, Sheng Liu, Hai‑Bin Shi
Pages: 7902-7910
Published online on: 05 April 2018

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Article

Response of decorin to different intensity treadmill running

Shao‑Yong Xu, Sheng‑Yao Liu, Lei Xu, Song‑Yun Deng, Yong‑Bin He, Shu‑Fen Li, Guo‑Xin Ni
Pages: 7911-7917
Published online on: 28 March 2018

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Article

A frameshift mutation in the CHM gene causes choroideremia with acute angle‑closure glaucoma

Pingbo Ouyang, Yun Li, Feng Zhang, Chengzhang Zhu, Beiji Zou, Jianlan Le, Lusi Zhang
Pages: 7918-7924
Published online on: 05 April 2018

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Article

Dehydrocostus lactone suppresses cell growth and induces apoptosis in recombinant human papilloma virus‑18 HaCaT cells via the PI3K/Akt signaling pathway

Wei Li, Yi Bing Ma, Ying Qiu Mao, Tong Lin
Pages: 7925-7930
Published online on: 28 March 2018

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Article

Pioglitazone/microRNA‑141/FOXA2: A novel axis in pancreatic β‑cells proliferation and insulin secretion

Xin Yu, Liyong Zhong
Pages: 7931-7938
Published online on: 28 March 2018

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Article

Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 cell line

Liubing Lin, Renye Que, Yanting Shen, Yirong Chen, Ni Yan, Yong Li
Pages: 7939-7946
Published online on: 05 April 2018

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Article

Crocin inhibits RANKL‑induced osteoclastogenesis by regulating JNK and NF‑κB signaling pathways

Liping Shi, Suping Zhao, Qian Chen, Youwei Wu, Jian Zhang, Na Li
Pages: 7947-7951
Published online on: 29 March 2018

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Article

Impact of epigallocatechin‑3‑gallate on expression of nuclear factor erythroid 2‑related factor 2 and γ‑glutamyl cysteine synthetase genes in oxidative stress‑induced mouse renal tubular epithelial cells

Xuanyi Du, Jinfeng Yu, Xiaohan Sun, Shaochuan Qu, Haitao Zhang, Mengying Hu, Shufen Yang, Ping Zhou
Pages: 7952-7958
Published online on: 28 March 2018

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Article

Anti‑oxidative and anti‑apoptotic neuroprotective effects of Azadirachta indica in Parkinson‑induced functional damage

Xin Xiang, Lin Wu, Lining Mao, Yiming Liu
Pages: 7959-7965
Published online on: 28 March 2018

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Article

Dysregulation of PTEN caused by the underexpression of microRNA‑130b is associated with the severity of lupus nephritis

Shupeng Wu, Jing Wang, Fang Li
Pages: 7966-7972
Published online on: 03 April 2018

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Article

miR‑152 regulates TGF‑β1‑induced epithelial‑mesenchymal transition by targeting HPIP in tubular epithelial cells

Ya‑Xian Ning, Xiao‑Yuan Wang, Jian‑Qin Wang, Rong Zeng, Gou‑Qin Wang
Pages: 7973-7979
Published online on: 03 April 2018

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Article

Gardenoside combined with ozone inhibits the expression of P2X3 and P2X7 purine receptors in rats with sciatic nerve injury

Mingdong Yu, Yong Zhao, Xiaoxia Zhang
Pages: 7980-7986
Published online on: 28 March 2018

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Article

β2‑adrenergic receptor functionality and genotype in two different models of chronic inflammatory disease: Liver cirrhosis and osteoarthritis

Reyes Roca, Pablo Esteban, Pedro Zapater, María‑Del‑Mar Inda, Anna Lucia Conte, Laura Gómez‑Escolar, Helena Martínez, José F. Horga, José M. Palazon, Ana M. Peiró
Pages: 7987-7995
Published online on: 29 March 2018

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Article

Procaine stimulates aquaporin‑5 expression in human salivary gland ductal cells via the suppression of DNA methyltransferase‑1

Fan Wu, Jintao Wang, Jianming Sun, Liman Shen, Meijuan Liu, Erjun Zhao
Pages: 7996-8002
Published online on: 29 March 2018

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Article

Correlation between autophagy levels in peripheral blood mononuclear cells and clinical parameters in patients with chronic obstructive pulmonary disease

Yanjun Wu, Bo Xu, Xin He, Bo Wu, Yunxiao Li, Ganggang Yu, Chunting Tan, Haoyan Wang
Pages: 8003-8009
Published online on: 29 March 2018

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Correction Open Access

[Corrigendum] Inhibitory activity of apogossypol in human prostate cancer in vitro and in vivo

Wenhua Zhan, Xingbin Hu, Jing Yi, Qunxing An, Xiaofeng Huang
Pages: 8010-8010
Published online on: 13 February 2018

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Correction Open Access

[Corrigendum] Altered expression of microRNA-98 in IL-1β-induced cartilage degradation and its role in chondrocyte apoptosis

Jing Wang, Lingqing Chen, Song Jin, Jun Lin, Hongmei Zheng, Hong Zhang, Hongtao Fan, Fang He, Sha Ma, Qin Li
Pages: 8011-8011
Published online on: 22 March 2018

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Review Open Access

The role of VEGF in the diagnosis and treatment of malignant pleural effusion in patients with non‑small cell lung cancer (Review)

Yao Chen, Nicholas W. Mathy, Hongda Lu
Pages: 8019-8030
Published online on: 23 April 2018

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Article Open Access

Regulation of the expression of tumor necrosis factor‑related genes by abnormal histone H3K27 acetylation: Implications for neural tube defects

Chunlei Wan, Xiaozhen Liu, Baoling Bai, Haiyan Cao, Huili Li, Qin Zhang
Pages: 8031-8038
Published online on: 19 April 2018

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Article Open Access

Diazoxide inhibits of ER stress‑mediated apoptosis during oxygen‑glucose deprivation in vitro and cerebral ischemia‑reperfusion in vivo

Xiaofeng Lei, Lijian Lei, Zhiqing Zhang, Yan Cheng
Pages: 8039-8046
Published online on: 24 April 2018

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Article Open Access

Hair growth is promoted by BeauTop via expression of EGF and FGF‑7

Chien‑Ying Lee, Chi‑Yu Yang, Ching‑Che Lin, Min‑Chien Yu, Shuenn‑Jyi Sheu, Yu‑Hsiang Kuan
Pages: 8047-8052
Published online on: 23 April 2018

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Article Open Access

Silencing activating transcription factor 2 promotes the anticancer activity of sorafenib in hepatocellular carcinoma cells

Lifang Luo, Lijing Cai, Laibang Luo, Zhimou Tang, Xiaohui Meng
Pages: 8053-8060
Published online on: 23 April 2018

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Article Open Access

Intraductal papillary mucinous neoplasms of the pancreas: Clinical association with KRAS

Xiao Yan Chang, Yan Wu, Yuan Li, Jing Wang, Jie Chen
Pages: 8061-8068
Published online on: 12 April 2018

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Article Open Access

Combined bioinformatics analysis reveals gene expression and DNA methylation patterns in osteoarthritis

Delei Song, Wei Qi, Ming Lv, Chun Yuan, Kangsong Tian, Feng Zhang
Pages: 8069-8078
Published online on: 12 April 2018

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Article Open Access

Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression

Man‑He Zhang, Xiu‑Min Zhou, Jian‑Zhong Cui, Kai‑Jie Wang, Yan Feng, Hong‑Ao Zhang
Pages: 8079-8086
Published online on: 19 April 2018

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Article

Pathogenetic mechanism of lipoid proteinosis caused by mutation of the extracellular matrix protein 1 gene Retraction in /10.3892/mmr.2019.9925

Dong Gao, Xianying Ma, Peiwen Lian, Surong Zhou, Jian Chen
Pages: 8087-8090
Published online on: 24 April 2018

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Article Open Access

Integrated bioinformatics analysis reveals key candidate genes and pathways in breast cancer

Yuzhi Wang, Yi Zhang, Qian Huang, Chengwen Li
Pages: 8091-8100
Published online on: 19 April 2018

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Article Open Access

Synergistic anticancer effects of bufalin and sorafenib by regulating apoptosis associated proteins

Haiyong Wang, Chenyue Zhang, Huiying Chi, Zhiqiang Meng
Pages: 8101-8110
Published online on: 24 April 2018

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Article Open Access

Combined inhibition of JAK1,2/Stat3‑PD‑L1 signaling pathway suppresses the immune escape of castration‑resistant prostate cancer to NK cells in hypoxia

Li‑Jun Xu, Qi Ma, Jin Zhu, Jian Li, Bo‑Xin Xue, Jie Gao, Chuan‑Yang Sun, Ya‑Chen Zang, Yi‑Bin Zhou, Dong‑Rong Yang, Yu‑Xi Shan
Pages: 8111-8120
Published online on: 20 April 2018

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Article Open Access

Effect of treadmill exercise on spatial navigation impairment associated with cerebellar Purkinje cell loss following chronic cerebral hypoperfusion

Jae‑Min Lee, Chang‑Ju Kim, Jong‑Min Park, Min Kyung Song, Youn‑Jung Kim
Pages: 8121-8128
Published online on: 19 April 2018

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Article Open Access

Analysis of NFKB2‑mediated regulation of mechanisms underlying the development of Hodgkin's lymphoma

Yunping Zhang, Laigen Tong, Sisi Chen, Wenzhong Wu, Li Wang
Pages: 8129-8136
Published online on: 20 April 2018

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Article Open Access

JWA suppresses the invasion of human breast carcinoma cells by downregulating the expression of CXCR4

Lingyun Xu, Lin Cheng, Fangliang Yang, Bei Pei, Xiaoan Liu, Jianwei Zhou, Yulan Zhu, Shui Wang
Pages: 8137-8144
Published online on: 11 April 2018

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Article Open Access

miR‑29a‑3p represses proliferation and metastasis of gastric cancer cells via attenuating HAS3 levels

Feihu Bai, Mengna Jiu, Yanjie You, Yaning Feng, Ruijuan Xin, Xiaogang Liu, Lirong Mo, Yongzhan Nie
Pages: 8145-8152
Published online on: 19 April 2018

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Article Open Access

Key signaling pathways, genes and transcription factors associated with hepatocellular carcinoma

Jingcheng Wang, Yang Tian, Hui Chen, Hui Li, Shusen Zheng
Pages: 8153-8160
Published online on: 12 April 2018

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Article Open Access

Age‑dependent decreases in insulin‑like growth factor‑I and its receptor expressions in the gerbil olfactory bulb

Tae‑Kyeong Lee, Bai Hui Chen, Jae‑Chul Lee, Myoung Cheol Shin, Jun Hwi Cho, Hyang‑Ah Lee, Jung Hoon Choi, In Koo Hwang, Il Jun Kang, Ji Hyeon Ahn, Joon Ha Park, Soo Young Choi, Moo‑Ho Won
Pages: 8161-8166
Published online on: 13 April 2018

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Article Open Access

Association between gastrointestinal motility and macrophage/mast cell distribution in mice during the healing stage after DSS‑induced colitis

Mio Kodani, Hirokazu Fukui, Toshihiko Tomita, Tadayuki Oshima, Jiro Watari, Hiroto Miwa
Pages: 8167-8172
Published online on: 24 April 2018

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Article Open Access

Loss of RUNX3 is significantly associated with advanced tumor grade and stage in endometrial cancers

Dongjun Jeong, Hyungjoo Kim, Aeli Ryu, Jaegun Sunwoo, Seung Do Choi, Gye Hyun Nam, Seob Jeon
Pages: 8173-8179
Published online on: 23 April 2018

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Article Open Access

c‑Jun suppresses the expression of WNT inhibitory factor 1 through transcriptional regulation and interaction with DNA methyltransferase 1 in gallbladder cancer

Bin Lin, Haijie Hong, Xiaojie Jiang, Chengzong Li, Siyuan Zhu, Nanhong Tang, Xiaoqian Wang, Feifei She, Yanling Chen
Pages: 8180-8188
Published online on: 16 April 2018

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Article Open Access

Identification of differential expression lncRNAs in gastric cancer using transcriptome sequencing and bioinformatics analyses

Yiyi Wang, Jue Zhang
Pages: 8189-8195
Published online on: 16 April 2018

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Article Open Access

Expression and functions of glutamate and γ‑aminobutyric acid transporters in ischemic models

Zhongrun Qian, Yingying Lin, Jin Xing, Yongming Qiu, Li Ren
Pages: 8196-8202
Published online on: 16 April 2018

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Article Open Access

Androgen receptor‑mediated upregulation of quaking affects androgen receptor‑related prostate cancer development and anti‑androgen receptor therapy

Keke Zhang, Fei Yan, Xiaoying Lei, Di Wei, Huanyu Lu, Zheng Zhu, An Xiang, Zichen Ye, Li Wang, Wanxiang Zheng, Xi'an Li, Jiarui Yuan, Zifan Lu, Jianlin Yuan
Pages: 8203-8211
Published online on: 13 April 2018

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Article Open Access

IPSC‑MSC inhibition assessment in Raw 264.7 cells following oxygen and glucose deprivation reveals a distinct function for cardiopulmonary resuscitation

Yi Yu, Dongping Wang, Hui Li, Yujie Liu, Zhao Xiang, Junlin Wu, Xiaoli Jing
Pages: 8212-8220
Published online on: 11 April 2018

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Article Open Access

PEEK‑biphasic bioceramic composites promote mandibular defect repair and upregulate BMP‑2 expression in rabbits

Hedong Yu, Yongji Chen, Min Mao, Dongyan Liu, Jun Ai, Weidong Leng
Pages: 8221-8227
Published online on: 11 April 2018

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Article Open Access

Study on the association between drug‑resistance and gene mutations of the active efflux pump acrAB‑tolC gene and its regulatory genes

Quan‑Ping Ma, Liang Su, Jing‑Wen Liu, Ming‑Xiao Yao, Guang‑Ying Yuan
Pages: 8228-8236
Published online on: 23 April 2018

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Article Open Access

Icariin promotes stable chondrogenic differentiation of bone marrow mesenchymal stem cells in self‑assembling peptide nanofiber hydrogel scaffolds

Zhicong Wang, Kaihua Li, Huijun Sun, Ji Wang, Zhuodong Fu, Mozhen Liu
Pages: 8237-8243
Published online on: 23 April 2018

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Article Open Access

MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Pages: 8244-8252
Published online on: 19 April 2018

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Article Open Access

Preliminary analysis of the protein profile in saliva during physiological term and preterm delivery

Maciej Łopucki, Jacek Wawrzykowski, Tomasz Gęca, Andrzej Miturski, Monika Franczyk, Marta Kankofer
Pages: 8253-8259
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Article Open Access

Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling Corrigendum in /10.3892/mmr.2025.13768

Long‑Ci Sun, Hai‑Xin Qian
Pages: 8260-8268
Published online on: 11 April 2018

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Article Open Access

Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts

Dan Liang, Ke‑Jing Wang, Zhi‑Qun Tang, Run‑He Liu, Fulei Zeng, Miao‑Ying Cheng, Qi‑Si Lian, Hong‑Kun Wu
Pages: 8269-8281
Published online on: 13 April 2018

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Article Open Access

LncSOX4 serves an oncogenic role in the tumorigenesis of epithelial ovarian cancer by promoting cell proliferation and inhibiting apoptosis

Yulan Liu, Yan Wang, Dongmei Yao, Diansheng Cui
Pages: 8282-8288
Published online on: 18 April 2018

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Article Open Access

Paclitaxel suppresses proliferation and induces apoptosis through regulation of ROS and the AKT/MAPK signaling pathway in canine mammary gland tumor cells

Xiaoli Ren, Bingbing Zhao, Hongjian Chang, Min Xiao, Yuhong Wu, Yun Liu
Pages: 8289-8299
Published online on: 11 April 2018

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Article Open Access

(‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway

Jia‑Wen Li, Xiao‑Yun Wang, Xin Zhang, Lei Gao, Li‑Feng Wang, Xin‑Hua Yin
Pages: 8300-8308
Published online on: 12 April 2018

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Article Open Access

Knockdown of long non‑coding RNA PVT1 reverses multidrug resistance in colorectal cancer cells

Heng Fan, Jian‑Hua Zhu, Xue‑Qing Yao
Pages: 8309-8315
Published online on: 20 April 2018

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Article Open Access

Liraglutide reduces hepatic glucolipotoxicity‑induced liver cell apoptosis through NRF2 signaling in Zucker diabetic fatty rats

Jun Guo, Cai Li, Chunxiao Yang, Bing Li, Jie Wei, Yajun Lin, Peng Ye, Gang Hu, Jian Li
Pages: 8316-8324
Published online on: 23 April 2018

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Article Open Access

Cell‑specific and roasting‑dependent regulation of the Keap1/Nrf2 pathway by coffee extracts

Alexandros Priftis, Antonia‑Eugenia Angeli‑Terzidou, Aristidis S. Veskoukis, Demetrios A. Spandidos, Dimitrios Kouretas
Pages: 8325-8331
Published online on: 24 April 2018

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Article

miR‑145‑5p reduces proliferation and migration of hepatocellular carcinoma by targeting KLF5

Hao Liang, Huiping Sun, Jinfeng Yang, Chun Yi
Pages: 8332-8338
Published online on: 13 April 2018

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Article

Aerobic exercise regulates blood lipid and insulin resistance via the toll‑like receptor 4‑mediated extracellular signal‑regulated kinases/AMP‑activated protein kinases signaling pathway

Mei Wang, Sen Li, Fubaihui Wang, Jinhui Zou, Yanfeng Zhang
Pages: 8339-8348
Published online on: 11 April 2018

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Article

PU.1 attenuates TNF‑α‑induced proliferation and cytokine release of rheumatoid arthritis fibroblast‑like synoviocytes by regulating miR‑155 activity

Zikang Xie, Yuxing Qu, Pengfei Shen, Bin Wang, Kang Wei, Bin Du
Pages: 8349-8356
Published online on: 23 April 2018

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Article

Effects of triptolide on the expression of MHC II in microglia in kainic acid‑induced epilepsy

Zheng Sun, Meng Du, Yao Lu, Chang‑Qian Zeng
Pages: 8357-8362
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Article

Interleukin 29 activates expression of tissue inhibitor of metalloproteinase 1 in macrophages via toll‑like receptor 2

Haoqiang Zhang, Bing Song, Shaoheng He
Pages: 8363-8368
Published online on: 11 April 2018

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Article

Parthenolide inhibits hydrogen peroxide‑induced osteoblast apoptosis

Weihuan Mao, Ziguan Zhu
Pages: 8369-8376
Published online on: 20 April 2018

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Article

MicroRNA‑146a/Toll‑like receptor 4 signaling protects against severe burn‑induced remote acute lung injury in rats via anti‑inflammation

Jinhua Luo, Jianhua Zhan, Haoyuan You, Xing Cheng
Pages: 8377-8384
Published online on: 12 April 2018

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Article

The therapeutic effect of artesunate on rosacea through the inhibition of the JAK/STAT signaling pathway Retraction in /10.3892/mmr.2023.13127

Ting Li, Qingwen Zeng, Xingming Chen, Guojiang Wang, Haiqing Zhang, Aihua Yu, Hairui Wang, Yang Hu
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Article

Whole‑genome sequencing of a monozygotic twin discordant for systemic lupus erythematosus

Fei Chen, Zhen Li, Rong Li, Yunlong Li
Pages: 8391-8396
Published online on: 20 April 2018

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Article

Silencing of casein kinase 2 inhibits PKC‑induced cell invasion by targeting MMP‑9 in MCF‑7 cells

Jeong‑Mi Kim, Eun‑Mi Noh, Hyun‑Kyung Song, Yong‑Ouk You, Sung Hoo Jung, Jong‑Suk Kim, Kang‑Beom Kwon, Young‑Rae Lee, Hyun Jo Youn
Pages: 8397-8402
Published online on: 13 April 2018

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Article

Preparation and characterization of calcium carbonate microspheres and their potential application as drug carriers

Juan Song, Ran Wang, Zao Liu, Huashan Zhang
Pages: 8403-8408
Published online on: 12 April 2018

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Article

Identification of TYR mutations in patients with oculocutaneous albinism

Wan Sun, Yanjie Shen, Shan Shan, Liyun Han, Yang Li, Zheng Zhou, Zilin Zhong, Jianjun Chen
Pages: 8409-8413
Published online on: 13 April 2018

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Article

Sirt1/Nrf2 signalling pathway prevents cognitive impairment in diabetic rats through anti‑oxidative stress induced by miRNA‑23b‑3p expression

Jinhua Han, Xiaoning Liu, Yingzhi Li, Jun Zhang, Haichi Yu
Pages: 8414-8422
Published online on: 12 April 2018

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Article

Expression and significance of autonomic nerves and α9 nicotinic acetylcholine receptor in colorectal cancer

Hui Zhou, Baojun Shi, Yitao Jia, Gang Qiu, Weiguang Yang, Jiali Li, Zhaolong Zhao, Jian Lv, Yanni Zhang, Zhongxin Li
Pages: 8423-8431
Published online on: 13 April 2018

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Article

HBx promotes the proliferative ability of HL‑7702 cells via the COX‑2/Wnt/β‑catenin pathway

Bi‑Yun Zheng, Wen‑Yu Gao, Xiao‑Yun Huang, Li‑Ying Lin, Xue‑Fen Fang, Zhi‑Xin Chen, Xiao‑Zhong Wang
Pages: 8432-8438
Published online on: 20 April 2018

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Article

Genetic analysis in a compound heterozygote family with familial hypercholesterolemia

Fang Wang, Qin Fan, Rong Tao, Gang Gu, Ruiyan Zhang, Rui Xi
Pages: 8439-8449
Published online on: 20 April 2018

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Article

microRNA‑145 modulates migration and invasion of bladder cancer cells by targeting N‑cadherin

Xue‑Feng Zhang, Xue‑Qi Zhang, Zhe‑Xing Chang, Cui‑Cui Wu, Hang Guo
Pages: 8450-8456
Published online on: 20 April 2018

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Article

MicroRNA‑34a mediates atrial fibrillation through regulation of Ankyrin‑B expression

Yun Zhu, Zezhou Feng, Wei Cheng, Yingbin Xiao
Pages: 8457-8465
Published online on: 12 April 2018

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Article

Infusion of adipose‑derived mesenchymal stem cells inhibits skeletal muscle mitsugumin 53 elevation and thereby alleviates insulin resistance in type 2 diabetic rats

Zihui Deng, Huiyan Xu, Jinying Zhang, Chen Yang, Liyuan Jin, Jiejie Liu, Haijing Song, Guanghui Chen, Weidong Han, Yiling Si
Pages: 8466-8474
Published online on: 19 April 2018

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Article

TNF‑α increases inflammatory factor expression in synovial fibroblasts through the toll‑like receptor‑3‑mediated ERK/AKT signaling pathway in a mouse model of rheumatoid arthritis

Fang‑Yuan Yu, Cong‑Qin Xie, Chang‑Liang Jiang, Ji‑Tong Sun, Xun‑Wu Huang
Pages: 8475-8483
Published online on: 19 April 2018

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Article

Bioinformatics analysis of the molecular mechanisms underlying traumatic spinal cord injury

Shu‑Jie Zhao, Wei Zhou, Jian Chen, Yong‑Jun Luo, Guo‑Yong Yin
Pages: 8484-8492
Published online on: 23 April 2018

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Article

MicroRNA‑29a is involved lipid metabolism dysfunction and insulin resistance in C2C12 myotubes by targeting PPARδ

Peng Wu, Qianyi Wang, Cuilian Jiang, Chen Chen, Yun Liu, Yajun Chen, Yu Zeng
Pages: 8493-8501
Published online on: 19 April 2018

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Article

miR‑149 promotes the myocardial differentiation of mouse bone marrow stem cells by targeting Dab2

Mingjun Lu, Lingling Xu, Min Wang, Tao Guo, Fuquan Luo, Nan Su, Shanghui Yi, Tao Chen
Pages: 8502-8509
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microRNA‑181a‑5p functions as an oncogene in renal cell carcinoma Corrigendum in /10.3892/mmr.2018.9117 Corrigendum in /10.3892/mmr.2024.13182

Yulin Lai, Liwen Zhao, Jia Hu, Jing Quan, Peijie Chen, Jinling Xu, Xin Guan, Yongqing Lai, Liangchao Ni
Pages: 8510-8517
Published online on: 19 April 2018

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Article

Oxidative and cytotoxic stress induced by inorganic granular and fibrous particles

Simone Helmig, Dirk Walter, Julia Putzier, Hagen Maxeiner, Sibylle Wenzel, Joachim Schneider
Pages: 8518-8529
Published online on: 23 April 2018

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Norepinephrine inhibits the cytotoxicity of NK92‑MI cells via the β2‑adrenoceptor/cAMP/PKA/p‑CREB signaling pathway

Zan Sun, Diandong Hou, Shuli Liu, Weixin Fu, Jiahui Wang, Zaifu Liang
Pages: 8530-8535
Published online on: 12 April 2018

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Article

High glucose promotes tumor cell proliferation and migration in lung adenocarcinoma via the RAGE‑NOXs pathway Corrigendum in /10.3892/mmr.2018.9555

Yuan‑Fan Liao, Sui Yin, Zi‑Qi Chen, Fan Li, Bo Zhao
Pages: 8536-8541
Published online on: 23 April 2018

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Inhibitors of heat shock protein 90 augment endothelin‑1‑induced heat shock protein 27 through the SAPK/JNK signaling pathway in osteoblasts

Kazuhiko Fujita, Takanobu Otsuka, Tetsu Kawabata, Go Sakai, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Haruhiko Tokuda
Pages: 8542-8547
Published online on: 12 April 2018

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PKR inhibition mediates endotoxin tolerance in macrophages through inactivation of PI3K/AKT signaling

Hailin Xu, Juan Chen, Xiang Si, Minying Chen, Fei Pei, Chunfang Qiu, Jianfeng Wu, Xiangdong Guan
Pages: 8548-8556
Published online on: 11 April 2018

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Article

Hedgehog signaling regulates the expression levels of inflammatory mediators in cigarette‑induced airway inflammation

Yi Guo, Guochao Shi, Huanying Wan, Min Zhou
Pages: 8557-8563
Published online on: 11 April 2018

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Impact Factor: 3.5

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CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

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Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
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Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
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Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

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Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Role of ubiquitin‑proteasome system in preeclampsia (Review)

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Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
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Published online on: 31 October 2025

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Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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