|
1
|
Movsas TZ, Weiner RL, Greenberg MB,
Holtzman DM and Galindo R: Pretreatment with human chorionic
gonadotropin protects the neonatal brain against the effects of
hypoxic-ischemic injury. Front Pediatr. 5:2322017. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ferriero DM: Neonatal brain injury. N Engl
J Med. 351:1985–1995. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Adluri RS, Thirunavukkarasu M, Zhan L,
Akita Y, Samuel SM, Otani H, Ho YS, Maulik G and Maulik N:
Thioredoxin 1 enhances neovascularization and reduces ventricular
remodeling during chronic myocardial infarction: A study using
thioredoxin 1 transgenic mice. J Mol Cell Cardiol. 50:239–247.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Greenberg DA and Jin K: From angiogenesis
to neuropathology. Nature. 438:954–959. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yellon DM and Hausenloy DJ: Myocardial
reperfusion injury. N Engl J Med. 357:1121–1135. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Eltzschig HK and Eckle T: Ischemia and
reperfusion-from mechanism to translation. Nat Med. 17:1391–1401.
2011. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Li L, Qu Y, Mao M, Xiong Y and Mu D: The
involvement of phosphoinositid 3-kinase/Akt pathway in the
activation of hypoxia-inducible factor-1alpha in the developing rat
brain after hypoxia-ischemia. Brain Res. 1197:152–158. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Fruman DA, Meyers RE and Cantley LC:
Phosphoinositide kinases. Annu Rev Biochem. 67:481–507. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Fresno Vara JA, Casado E, de Castro J,
Cejas P, Belda-Iniesta C and González-Barón M: PI3K/Akt signalling
pathway and cancer. Cancer Treat Rev. 30:193–204. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Pawson T and Nash P: Protein-protein
interactions define specificity in signal transduction. Genes Dev.
14:1027–1047. 2000.PubMed/NCBI
|
|
11
|
Zhang F, Ding T, Yu L, Zhong Y, Dai H and
Yan M: Dexmedetomidine protects against oxygen-glucose
deprivation-induced injury through the I2 imidazoline
receptor-PI3K/AKT pathway in rat C6 glioma cells. J Pharm
Pharmacol. 64:120–127. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ciuffreda L, Falcone I, Incani UC, Del
Curatolo A, Conciatori F, Matteoni S, Vari S, Vaccaro V, Cognetti F
and Milella M: PTEN expression and function in adult cancer stem
cells and prospects for therapeutic targeting. Adv Biol Regul.
56:66–80. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Cantley LC: The phosphoinositide 3-kinase
pathway. Science. 296:1655–1657. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Han JQ, Yu KY and He M: Effects of
puerarin on the neurocyte apoptosis and p-Akt (Ser473) expressions
in rats with cerebral ischemia/reperfusion injury. Zhongguo Zhong
Xi Yi Jie He Za Zhi. 32:1069–1072. 2012.(In Chinese). PubMed/NCBI
|
|
15
|
Liu BN, Han BX and Liu F: Neuroprotective
effect of pAkt and HIF-1α on ischemia rats. Asian Pac J Trop Med.
7:221–225. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Li D, Qu Y, Mao M, Zhang X, Li J, Ferriero
D and Mu D: Involvement of the PTEN-AKT-FOXO3a pathway in neuronal
apoptosis in developing rat brain after hypoxia-ischemia. J Cereb
Blood Flow Metab. 29:1903–1913. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Wang Z, Wang Y, Ye J, Lu X, Cheng Y, Xiang
L, Chen L, Feng W, Shi H, Yu X, et al: bFGF attenuates endoplasmic
reticulum stress and mitochondrial injury on myocardial
ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway. J
Cell Mol Med. 19:595–607. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Liu MH, Li GH, Peng LJ, Qu SL, Zhang Y,
Peng J, Luo XY, Hu HJ, Ren Z, Liu Y, et al: PI3K/Akt/FoxO3a
signaling mediates cardioprotection of FGF-2 against hydrogen
peroxide-induced apoptosis in H9c2 cells. Mol Cell Biochem.
414:57–66. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Correia SC, Cardoso S, Santos RX, Carvalho
C, Santos MS, Perry G, Smith MA and Moreira PI: New insights into
the mechanisms of mitochondrial preconditioning-triggered
neuroprotection. Curr Pharm Des. 17:3381–3389. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zhong H, Chiles K, Feldser D, Laughner E,
Hanrahan C, Georgescu MM, Simons JW and Semenza GL: Modulation of
hypoxia-inducible factor 1alpha expression by the epidermal growth
factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human
prostate cancer cells: Implications for tumor angiogenesis and
therapeutics. Cancer Res 60: 1541–1545, 2000. Cancer Res 60:
1541–1545, 2000. 60: 1541–1545, 2000:1541-1545, 2000–1545, 2000.
2000.
|
|
21
|
Wang Z, Zhang H, Xu X, Shi H, Yu X, Wang
X, Yan Y, Fu X, Hu H, Li X and Xiao J: bFGF inhibits ER stress
induced by ischemic oxidative injury via activation of the PI3K/Akt
and ERK1/2 pathways. Toxicol Lett. 212:137–146. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kunze R, Zhou W, Veltkamp R, Wielockx B,
Breier G and Marti HH: Neuron-specific prolyl-4-hydroxylase domain
2 knockout reduces brain injury after transient cerebral ischemia.
Stroke. 43:2748–2756. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Semenza GL: Hypoxia-inducible factors in
physiology and medicine. Cell. 148:399–408. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Jain T, Nikolopoulou EA, Xu Q and Qu A:
Hypoxia inducible factor as a therapeutic target for
atherosclerosis. Pharmacol Ther. 183:22–33. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Xiao Y, Peng H, Hong C, Chen Z, Deng X,
Wang A, Yang F, Yang L, Chen C and Qin X: PDGF promotes the warburg
effect in pulmonary arterial smooth muscle cells via activation of
the PI3K/AKT/mTOR/HIF-1α signaling pathway. Cell Physiol Biochem.
42:1603–1613. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Laughner E, Taghavi P, Chiles K, Mahon PC
and Semenza GL: HER2 (neu) signaling increases the rate of
hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel
mechanism for HIF-1-mediated vascular endothelial growth factor
expression. Mol Cell Biol. 21:3995–4004. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Yang XM, Wang YS, Zhang J, Li Y, Xu JF,
Zhu J, Zhao W, Chu DK and Wiedemann P: Role of PI3K/Akt and MEK/ERK
in mediating hypoxia-induced expression of HIF-1alpha and VEGF in
laser-induced rat choroidal neovascularization. Invest Ophthalmol
Vis Sci. 50:1873–1879. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Karar J, Cerniglia GJ, Lindsten T,
Koumenis C and Maity A: Dual PI3K/mTOR inhibitor NVP-BEZ235
suppresses hypoxia-inducible factor (HIF)-1α expression by blocking
protein translation and increases cell death under hypoxia. Cancer
Biol Ther. 13:1102–1111. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
van den Beucken T, Koritzinsky M and
Wouters BG: Translational control of gene expression during
hypoxia. Cancer Biol Ther. 5:749–755. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Hudson CC, Liu M, Chiang GG, Otterness DM,
Loomis DC, Kaper F, Giaccia AJ and Abraham RT: Regulation of
hypoxia-inducible factor 1alpha expression and function by the
mammalian target of rapamycin. Mol Cell Biol. 22:7004–7014. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Ivan M and Kaelin WG Jr: The von
Hippel-Lindau tumor suppressor protein. Curr Opin Genet Dev.
11:27–34. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Bai S, Datta J, Jacob ST and Ghoshal K:
Treatment of PC12 cells with nerve growth factor induces
proteasomal degradation of T-cadherin that requires tyrosine
phosphorylation of its cadherin domain. J Biol Chem.
282:27171–27180. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Dimova EY, Michiels C and Kietzmann T:
Kinases as upstream regulators of the HIF system: their emerging
potential as anti-cancer drug targets. Curr Pharm Des.
15:3867–3877. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Yao HC, Zhou M, Zhou YH, Wang LH, Zhang
DY, Han QF, Liu T, Wu L, Tian KL and Zhang M: Intravenous high
mobility group box 1 upregulates the expression of HIF-1α in the
myocardium via a protein kinase B-dependent pathway in rats
following acute myocardial ischemia. Mol Med Rep. 13:1211–1219.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Zaman K, Ryu H, Hall D, O'Donovan K, Lin
KI, Miller MP, Marquis JC, Baraban JM, Semenza GL and Ratan RR:
Protection from oxidative stress-induced apoptosis in cortical
neuronal cultures by iron chelators is associated with enhanced DNA
binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased
expression of glycolytic enzymes, p21 (waf1/cip1), and
erythropoietin. J Neurosci 19: 9821–9830, 1999. J Neurosci 19:
9821–9830, 1999. 19: 9821–9830, 1999:9821-9830, 1999–9830, 1999.
1999.
|
|
36
|
Hamrick SE, McQuillen PS, Jiang X, Mu D,
Madan A and Ferriero DM: A role for hypoxia-inducible factor-1alpha
in desferoxamine neuroprotection. Neurosci Lett. 379:96–100. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Sharp FR and Bernaudin M: HIF1 and oxygen
sensing in the brain. Nat Rev Neurosci. 5:437–448. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Semenza GL: Angiogenesis in ischemic and
neoplastic disorders. Annu Rev Med. 54:17–28. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Blanco Pampin J, Garcia Rivero SA, Otero
Cepeda XL, Vázquez Boquete A, Forteza Vila J and Hinojal Fonseca R:
Immunohistochemical expression of HIF-1alpha in response to early
myocardial ischemia. J Forensic Sci. 51:120–124. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Shi H: Hypoxia inducible factor 1 as a
therapeutic target in ischemic stroke. Curr Med Chem. 16:4593–4600.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Manalo DJ, Rowan A, Lavoie T, Natarajan L,
Kelly BD, Ye SQ, Garcia JG and Semenza GL: Transcriptional
regulation of vascular endothelial cell responses to hypoxia by
HIF-1. Blood. 105:659–669. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Minet E, Michel G, Remacle J and Michiels
C: Role of HIF-1 as a transcription factor involved in embryonic
development, cancer progression and apoptosis (review). Int J Mol
Med. 5:253–259. 2000.PubMed/NCBI
|
|
43
|
Semenza GL: Regulation of cancer cell
metabolism by hypoxia-inducible factor 1. Semin Cancer Biol.
19:12–16. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Adekola K, Rosen ST and Shanmugam M:
Glucose transporters in cancer metabolism. Curr Opin Oncol.
24:650–654. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Semenza GL: Hypoxia-inducible factor 1:
Regulator of mitochondrial metabolism and mediator of ischemic
preconditioning. Biochim Biophys Acta. 1813:1263–1268. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Kim JW, Tchernyshyov I, Semenza GL and
Dang CV: HIF-1-mediated expression of pyruvate dehydrogenase
kinase: a metabolic switch required for cellular adaptation to
hypoxia. Cell Metab. 3:177–185. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Simon MC: Coming up for air: HIF-1 and
mitochondrial oxygen consumption. Cell Metab. 3:150–151. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Chen C, Pore N, Behrooz A, Ismail-Beigi F
and Maity A: Regulation of glut1 mRNA by hypoxia-inducible
factor-1. Interaction between H-ras and hypoxia. J Biol Chem.
276:9519–9525. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Lu H, Forbes RA and Verma A:
Hypoxia-inducible factor 1 activation by aerobic glycolysis
implicates the Warburg effect in carcinogenesis. J Biol Chem.
277:23111–23115. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Semenza GL: HIF-1 mediates the Warburg
effect in clear cell renal carcinoma. J Bioenerg Biomembr.
39:231–234. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Maxwell PH, Pugh CW and Ratcliffe PJ:
Activation of the HIF pathway in cancer. Curr Opin Genet Dev.
11:293–299. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Semenza GL: HIF-1: Upstream and downstream
of cancer metabolism. Curr Opin Genet Dev. 20:51–56. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Nagy MA: HIF-1 is the commander of
gateways to cancer. J Cancer Sei Ther. 3:35–40. 2011.
|
|
54
|
Courtnay R, Ngo DC, Malik N, Ververis K,
Tortorella SM and Karagiannis TC: Cancer metabolism and the Warburg
effect: The role of HIF-1 and PI3K. Mol Biol Rep. 42:841–851. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Dang CV: Links between metabolism and
cancer. Genes Dev. 26:877–890. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Martini M, De Santis MC, Braccini L,
Gulluni F and Hirsch E: PI3K/AKT signaling pathway and cancer: an
updated review. Ann Med. 46:372–383. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Koukourakis MI, Giatromanolaki A, Sivridis
E, Gatter KC and Harris AL; Tumour Angiogenesis Research Group, :
Lactate dehydrogenase 5 expression in operable colorectal cancer:
Strong association with survival and activated vascular endothelial
growth factor pathway-a report of the Tumour Angiogenesis Research
Group. J Clin Oncol. 24:4301–4308. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Solaini G, Baracca A, Lenaz G and Sgarbi
G: Hypoxia and mitochondrial oxidative metabolism. Biochim Biophys
Acta. 1797:1171–1177. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Samuel SM, Akita Y, Paul D,
Thirunavukkarasu M, Zhan L, Sudhakaran PR, Li C and Maulik N:
Coadministration of adenoviral vascular endothelial growth factor
and angiopoietin-1 enhances vascularization and reduces ventricular
remodeling in the infarcted myocardium of type 1 diabetic rats.
Diabetes. 59:51–60. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Bai WW, Xing YF, Wang B, Lu XT, Wang YB,
Sun YY, Liu XQ, Guo T and Zhao YX: Tongxinluo improves cardiac
function and ameliorates ventricular remodeling in mice model of
myocardial infarction through enhancing angiogenesis. Evid Based
Complement Alternat Med 2013. 8132472013.
|
|
61
|
Patten RD, Pourati I, Aronovitz MJ, Baur
J, Celestin F, Chen X, Michael A, Haq S, Nuedling S, Grohe C, et
al: 17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in
vitro via activation of phospho-inositide-3 kinase/Akt signaling.
Circ Res. 95:692–699. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
He Z, Opland DM, Way KJ, Ueki K, Bodyak N,
Kang PM, Izumo S, Kulkarni RN, Wang B, Liao R, et al: Regulation of
vascular endothelial growth factor expression and vascularization
in the myocardium by insulin receptor and PI3K/Akt pathways in
insulin resistance and ischemia. Arterioscler Thromb Vasc Biol.
26:787–793. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Graupera M, Guillermet-Guibert J, Foukas
LC, Phng LK, Cain RJ, Salpekar A, Pearce W, Meek S, Millan J,
Cutillas PR, et al: Angiogenesis selectively requires the p110alpha
isoform of PI3K to control endothelial cell migration. Nature.
453:662–666. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Sumida A, Horiba M, Ishiguro H, Takenaka
H, Ueda N, Ooboshi H, Opthof T, Kadomatsu K and Kodama I: Midkine
gene transfer after myocardial infarction in rats prevents
remodelling and ameliorates cardiac dysfunction. Cardiovasc Res.
86:113–121. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Dutta PR and Maity A: Cellular responses
to EGFR inhibitors and their relevance to cancer therapy. Cancer
Lett. 254:165–177. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Chen JX and Meyrick B: Hypoxia increases
Hsp90 binding to eNOS via PI3K-Akt in porcine coronary artery
endothelium. Lab Invest. 84:182–190. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Hirota K and Semenza GL: Regulation of
angiogenesis by hypoxia-inducible factor 1. Crit Rev Oncol Hematol.
59:15–26. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Kido M, Du L, Sullivan CC, Li X, Deutsch
R, Jamieson SW and Thistlethwaite PA: Hypoxia-inducible factor
1-alpha reduces infarction and attenuates progression of cardiac
dysfunction after myocardial infarction in the mouse. J Am Coll
Cardiol. 46:2116–2124. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Khan M, Varadharaj S, Ganesan LP, Shobha
JC, Naidu MU, Parinandi NL, Tridandapani S, Kutala VK and Kuppusamy
P: C-phycocyanin protects against ischemia-reperfusion injury of
heart through involvement of p38 MAPK and ERK signaling. Am J
Physiol Heart Circ Physiol. 290:H2136–H2145. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Tian T, Nan KJ, Wang SH, Liang X, Lu CX,
Guo H, Wang WJ and Ruan ZP: PTEN regulates angiogenesis and VEGF
expression through phosphatase-dependent and -independent
mechanisms in HepG2 cells. Carcinogenesis. 31:1211–1219. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Forsythe JA, Jiang BH, Iyer NV, Agani F,
Leung SW, Koos RD and Semenza GL: Activation of vascular
endothelial growth factor gene transcription by hypoxia-inducible
factor 1. Mol Cell Biol. 16:4604–4613. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Gray MJ, Zhang J, Ellis LM, Semenza GL,
Evans DB, Watowich SS and Gallick GE: HIF-1alpha, STAT3, CBP/p300
and Ref-1/APE are components of a transcriptional complex that
regulates Src-dependent hypoxia-induced expression of VEGF in
pancreatic and prostate carcinomas. Oncogene. 24:3110–3120. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Guo S, Miyake M, Liu KJ and Shi H:
Specific inhibition of hypoxia inducible factor 1 exaggerates cell
injury induced by in vitro ischemia through deteriorating cellular
redox environment. J Neurochem. 108:1309–1321. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Wang Z and Si LY: Hypoxia-inducible
factor-1α and vascular endothelial growth factor in the
cardioprotective effects of intermittent hypoxia in rats. Ups J Med
Sci. 118:65–74. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Carmeliet P, Dor Y, Herbert JM, Fukumura
D, Brusselmans K, Dewerchin M, Neeman M, Bono F, Abramovitch R,
Maxwell P, et al: Role of HIF-1alpha in hypoxia-mediated apoptosis,
cell proliferation and tumour angiogenesis. Nature. 394:485–490.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Halterman MW and Federoff HJ: HIF-1alpha
and p53 promote hypoxia-induced delayed neuronal death in models of
CNS ischemia. Exp Neurol. 159:65–72. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Halterman MW, Miller CC and Federoff HJ:
Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed
neuronal death that involves p53. J Neurosci. 19:6818–6824. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Chen C, Hu Q, Yan J, Lei J, Qin L, Shi X,
Luan L, Yang L, Wang K, Han J, et al: Multiple effects of 2ME2 and
D609 on the cortical expression of HIF-1alpha and apoptotic genes
in a middle cerebral artery occlusion-induced focal ischemia rat
model. J Neurochem. 102:1831–1841. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Zhang H, Bosch-Marce M, Shimoda LA, Tan
YS, Baek JH, Wesley JB, Gonzalez FJ and Semenza GL: Mitochondrial
autophagy is an HIF-1-dependent adaptive metabolic response to
hypoxia. J Biol Chem. 283:10892–10903. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Sun Y, Chen X, Zhang X, Shen X, Wang M,
Wang X, Liu WC, Liu CF, Liu J, Liu W and Jin X: β2-adrenergic
receptor-mediated HIF-1α upregulation mediates blood brain barrier
damage in acute cerebral ischemia. Front Mol Neurosci. 10:2572017.
View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Wong CC, Gilkes DM, Zhang H, Chen J, Wei
H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, et al:
Hypoxia-inducible factor 1 is a master regulator of breast cancer
metastatic niche formation. Proc Natl Acad Sci USA. 108:pp.
16369–16374. 2011; View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Wong CC, Zhang H, Gilkes DM, Chen J, Wei
H, Chaturvedi P, Hubbi ME and Semenza GL: Inhibitors of
hypoxia-inducible factor 1 block breast cancer metastatic niche
formation and lung metastasis. J Mol Med (Berl). 90:803–815. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Liu ZJ, Semenza GL and Zhang HF:
Hypoxia-inducible factor 1 and breast cancer metastasis. J Zhejiang
Univ Sci B. 16:32–43. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Baranova O, Miranda LF, Pichiule P,
Dragatsis I, Johnson RS and Chavez JC: Neuron-specific inactivation
of the hypoxia inducible factor 1 alpha increases brain injury in a
mouse model of transient focal cerebral ischemia. J Neurosci.
27:6320–6332. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Helton R, Cui J, Scheel JR, Ellison JA,
Ames C, Gibson C, Blouw B, Ouyang L, Dragatsis I, Zeitlin S, et al:
Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces
rather than increases hypoxic-ischemic damage. J Neurosci.
25:4099–4107. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
86
|
Filippi I, Morena E, Aldinucci C, Carraro
F, Sozzani S and Naldini A: Short-term hypoxia enhances the
migratory capability of dendritic cell through HIF-1α and PI3K/Akt
pathway. J Cell Physiol. 229:2067–2076. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Hu X, Wei L, Taylor TM, Wei J, Zhou X,
Wang JA and Yu SP: Hypoxic preconditioning enhances bone marrow
mesenchymal stem cell migration via Kv2.1 channel and FAK
activation. Am J Physiol Cell Physiol. 301:C362–C372. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Hu X, Yu SP, Fraser JL, Lu Z, Ogle ME,
Wang JA and Wei L: Transplantation of hypoxia-preconditioned
mesenchymal stem cells improves infarcted heart function via
enhanced survival of implanted cells and angiogenesis. J Thorac
Cardiovasc Surg. 135:799–808. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Jian KT, Shi Y, Zhang Y, Mao YM, Liu JS
and Xue FL: Time course effect of hypoxia on bone marrow-derived
endothelial progenitor cells and their effects on left ventricular
function after transplanted into acute myocardial ischemia rat. Eur
Rev Med Pharmacol Sci. 19:1043–1054. 2015.PubMed/NCBI
|
|
90
|
Ginouvès A, Ilc K, Macias N, Pouysségur J
and Berra E: PHDs overactivation during chronic hypoxia
‘desensitizes’ HIFalpha and protects cells from necrosis. Proc Natl
Acad Sci USA. 105:pp. 4745–4750. 2008; View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Poitz DM, Augstein A, Hesse K, Christoph
M, Ibrahim K, Braun-Dullaeus RC, Strasser RH and Schmeißer A:
Regulation of the HIF-system in human macrophages-differential
regulation of HIF-α subunits under sustained hypoxia. Mol Immunol.
57:226–235. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Higgins RD, Raju T, Edwards AD, Azzopardi
DV, Bose CL, Clark RH, Ferriero DM, Guillet R, Gunn AJ, Hagberg H,
et al: Hypothermia and other treatment options for neonatal
encephalopathy: An executive summary of the Eunice Kennedy Shriver
NICHD workshop. J Pediatr. 159:851–858.e1. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
93
|
Shankaran S, Pappas A, McDonald SA, Vohr
BR, Hintz SR, Yolton K, Gustafson KE, Leach TM, Green C, Bara R, et
al: Childhood outcomes after hypothermia for neonatal
encephalopathy. N Engl J Med. 366:2085–2092. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
94
|
Huang J, Zhang L, Qu Y, Zhou Y, Zhu J, Li
Y, Zhu T, Zhao F, Tang J and Mu D: Histone acetylation of
oligodendrocytes protects against white matter injury induced by
inflammation and hypoxia-ischemia through activation of BDNF-TrkB
signaling pathway in neonatal rats. Brain Res. 1688:33–46. 2018.
View Article : Google Scholar : PubMed/NCBI
|
