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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2018 Volume 18 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

PI3K/Akt and HIF‑1 signaling pathway in hypoxia‑ischemia (Review)

Zhen Zhang, Li Yao, Jinhua Yang, Zhenkang Wang, Gang Du
Pages: 3547-3554
Published online on: 09 August 2018

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Article Open Access

Isolation and characterization of minipig perivascular stem cells for bone tissue engineering

Zhen Cui, Chenshuang Li, Nan Jiang, Ci Zhang, Yiran Wang, Hongyun Gao, Yanheng Zhou
Pages: 3555-3562
Published online on: 21 August 2018

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Article Open Access

Ghrelin improves pilocarpine‑induced cerebral cortex inflammation in epileptic rats by inhibiting NF‑κB and TNF‑α

Kun Han, Qing‑Yi Wang, Cai‑Xia Wang, Shao‑Yong Luan, Wen‑Peng Tian, Yue Wang, Rui‑Yun Zhang
Pages: 3563-3568
Published online on: 10 August 2018

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Article Open Access

Identification of protein complexes associated with myocardial infarction using a bioinformatics approach

Nianhui Jiao, Yongjie Qi, Changli Lv, Hongjun Li, Fengyong Yang
Pages: 3569-3576
Published online on: 21 August 2018

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Article Open Access

MicroRNA‑34b promotes proliferation, migration and invasion of Ewing's sarcoma cells by downregulating Notch1

Qunshan Lu, Mei Lu, Dong Li, Shuai Zhang
Pages: 3577-3588
Published online on: 09 August 2018

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Article Open Access

Establishment of a SVM classifier to predict recurrence of ovarian cancer

Jinting Zhou, Lin Li, Liling Wang, Xiaofang Li, Hui Xing, Li Cheng
Pages: 3589-3598
Published online on: 08 August 2018

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Article Open Access

Tetraspanin family identified as the central genes detected in gastric cancer using bioinformatics analysis

Weiwei Qi, Libin Sun, Ning Liu, Shufen Zhao, Jing Lv, Wensheng Qiu
Pages: 3599-3610
Published online on: 08 August 2018

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Article Open Access

Downregulation of Glt25d1 aggravates carbon tetrachloride‑induced acute hepatic injury through activation of the TGF‑β1/Smad2 signaling pathway

Xiaohui Ye, Lingling He, Jiali Ma, Yufeng Li, Manka Zhang, Junru Yang, Jian Zhang, Fan Xiao, Hongshan Wei
Pages: 3611-3618
Published online on: 16 August 2018

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Article

Galangin protects human rheumatoid arthritis fibroblast‑like synoviocytes via suppression of the NF‑κB/NLRP3 pathway

Qiang Fu, Yuzhong Gao, Hui Zhao, Zaijun Wang, Jian Wang
Pages: 3619-3624
Published online on: 22 August 2018

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Article

Renoprotection of dapagliflozin in human renal proximal tubular cells via the inhibition of the high mobility group box 1‑receptor for advanced glycation end products‑nuclear factor‑κB signaling pathway

Di Yao, Suyu Wang, Min Wang, Weiping Lu
Pages: 3625-3630
Published online on: 17 August 2018

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Article Open Access

MicroRNA‑675‑3p promotes esophageal squamous cell cancer cell migration and invasion

Qi Xiao, Tianming Chen, Yao Wu, Wenxiu Wu, Yandi Xu, Zhunan Gong, Shilin Chen
Pages: 3631-3640
Published online on: 09 August 2018

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Article Open Access

Oleanolic acid protects against oxidative stress‑induced human umbilical vein endothelial cell injury by activating AKT/eNOS signaling

Wei Zhang, Jian Feng, Biao Cheng, Qing Lu, Xiaoping Chen
Pages: 3641-3648
Published online on: 03 August 2018

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Article Open Access

Hydroxysafflor yellow A protects against angiotensin II‑induced hypertrophy

Bin Ni, Donglai Zhou, Yunyan Jing, Shanxin Liu
Pages: 3649-3656
Published online on: 17 August 2018

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Article Open Access

Dysregulation of lncRNAs GM5524 and GM15645 involved in high‑glucose‑induced podocyte apoptosis and autophagy in diabetic nephropathy

Yamin Feng, Sheng Chen, Jiarong Xu, Qun Zhu, Xiaolong Ye, Dafa Ding, Weihao Yao, Yibing Lu
Pages: 3657-3664
Published online on: 21 August 2018

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Article Open Access

Absence of Sirt3 aggravates cisplatin nephrotoxicity via enhanced renal tubular apoptosis and inflammation

Dal Kim, Woong Park, Sik Lee, Won Kim, Sung Kwang Park, Kyung Pyo Kang
Pages: 3665-3672
Published online on: 03 August 2018

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Article Open Access

Transcriptome sequencing identifies key pathways and genes involved in gastric adenocarcinoma

Wenhu Zhang, Shaozhuang Liu, Hanxiang Zhan, Zhibo Yan, Guangyong Zhang
Pages: 3673-3682
Published online on: 09 August 2018

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Article Open Access

In vitro and in vivo study of the expression of the Syk/Ras/c‑Fos pathway in chronic glomerulonephritis

Jiarong Gao, Liangbing Wei, Junmei Song, Hui Jiang, Yachen Gao, Xi Wu, Shuangzhi Xu
Pages: 3683-3690
Published online on: 03 August 2018

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Article Open Access

Sinomenine alleviates dextran sulfate sodium‑induced colitis via the Nrf2/NQO‑1 signaling pathway

Yan Zhou, Hanyang Liu, Jun Song, Liang Cao, Liming Tang, Chunjian Qi
Pages: 3691-3698
Published online on: 10 August 2018

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Article Open Access

Aloperine inhibits proliferation, migration and invasion and induces apoptosis by blocking the Ras signaling pathway in human breast cancer cells

Delong Tian, Yanhai Li, Xinxin Li, Zhenzhen Tian
Pages: 3699-3710
Published online on: 22 August 2018

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Article Open Access

Therapeutic effects of bee venom on experimental atopic dermatitis

Hyemin Gu, Woon‑Hae Kim, Hyun‑Jin An, Jung‑Yeon Kim, Mi‑Gyeong Gwon, Sang Mi Han, Jaechan Leem, Kwan‑Kyu Park
Pages: 3711-3718
Published online on: 17 August 2018

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Article Open Access

PDGF‑BB promotes the differentiation and proliferation of MC3T3‑E1 cells through the Src/JAK2 signaling pathway

Qi Liu, Yunfeng Zhou, Zubing Li
Pages: 3719-3726
Published online on: 03 August 2018

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Article Open Access

Novel prognostic biomarkers of gastric cancer based on gene expression microarray: COL12A1, GSTA3, FGA and FGG

Shijie Duan, Baocheng Gong, Pengliang Wang, Hanwei Huang, Lei Luo, Funan Liu
Pages: 3727-3736
Published online on: 09 August 2018

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Article Open Access

Bioinformatics analysis to screen for critical genes between survived and non‑survived patients with sepsis

Yanfeng Wu, Lei Zhang, Ying Zhang, Yong Zhen, Shouyue Liu
Pages: 3737-3743
Published online on: 21 August 2018

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Article Open Access

Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Pages: 3744-3750
Published online on: 06 August 2018

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Article Open Access

ASCL2 expression contributes to gastric tumor migration and invasion by downregulating miR223 and inducing EMT

Qingsong Zuo, Jie Wang, Chao Chen, Yong Zhang, Dian‑Xu Feng, Ronghua Zhao, Teng Chen
Pages: 3751-3759
Published online on: 08 August 2018

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Article Open Access

Salidroside mitigates hypoxia/reoxygenation injury by alleviating endoplasmic reticulum stress‑induced apoptosis in H9c2 cardiomyocytes Retraction in /10.3892/mmr.2024.13320

Meng‑Yao Sun, Da‑Shi Ma, Song Zhao, Lei Wang, Chun‑Ye Ma, Yang Bai
Pages: 3760-3768
Published online on: 20 August 2018

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Article Open Access

EGFR may participate in immune evasion through regulation of B7‑H5 expression in non‑small cell lung carcinoma

Zhaohui Dong, Lanying Zhang, Wei Xu, Gensheng Zhang
Pages: 3769-3779
Published online on: 08 August 2018

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Article Open Access

C‑C chemokine receptor type 3 gene knockout alleviates inflammatory responses in allergic rhinitis model mice by regulating the expression of eosinophil granule proteins and immune factors

Xinhua Zhu, Ke Liu, Jialin Wang, Haisen Peng, Qibin Pan, Shuhong Wu, Yinli Jiang, Yuehui Liu
Pages: 3780-3790
Published online on: 10 August 2018

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Article Open Access

Theaflavins attenuate ethanol‑induced oxidative stress and cell apoptosis in gastric mucosa epithelial cells via downregulation of the mitogen‑activated protein kinase pathway

Zheng Wang, Hesheng Luo, Hong Xia
Pages: 3791-3799
Published online on: 03 August 2018

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Article Open Access

Silencing of PYGB suppresses growth and promotes the apoptosis of prostate cancer cells via the NF‑κB/Nrf2 signaling pathway

Zhen Wang, Gang Han, Qinghong Liu, Wenyuan Zhang, Jinshan Wang
Pages: 3800-3808
Published online on: 14 August 2018

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Article Open Access

proBDNF inhibits the proliferation and migration of OLN‑93 oligodendrocytes

Shen Liu, Wei Guo, Hengxing Zhou, Liang Tang, Shiqing Feng, Jin‑Hua Zhong, Xin‑Fu Zhou
Pages: 3809-3817
Published online on: 21 August 2018

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Article Open Access

Effects of Toll‑like receptor 9 and CpG oligodeoxynucleotides 1826 on sodium taurocholate‑induced acute pancreatitis rats

Liang Sun, Yuanhua Li, Huayou Luo, Kunhua Wang, Li Li, Yujian Zeng
Pages: 3818-3824
Published online on: 03 August 2018

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Article Open Access

Identification of pathways significantly associated with spondyloarthropathy/ankylosing spondylitis using the sub‑pathway method

Ming Ding, Ting‑Jin Guan, Chuan‑Yin Wei, Bo‑Hua Chen
Pages: 3825-3833
Published online on: 17 August 2018

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Article Open Access

Effects of Panax ginseng C.A. Meyer extract on the offspring of adult mice with maternal immune activation

Hak‑Jae Kim, Hansol Won, Jiyun Im, Hwayoung Lee, Jiwoo Park, Sanghyun Lee, Young‑Ock Kim, Hyung‑Ki Kim, Jun‑Tack Kwon
Pages: 3834-3842
Published online on: 22 August 2018

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Article Open Access

Overexpression of KLF5 inhibits puromycin‑induced apoptosis of podocytes

Yang Li, Xiaoni Sui, Xueqing Hu, Zhao Hu
Pages: 3843-3849
Published online on: 09 August 2018

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Article Open Access

Identification of LINC01279 as a cell cycle‑associated long non‑coding RNA in endometriosis with GBA analysis

Jie Liu, Qi Wang, Rongrong Zhang, Chu Zhang, Jihui Lin, Xiaojie Huang
Pages: 3850-3858
Published online on: 14 August 2018

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Article Open Access

Correlation between DEC1/DEC2 and epithelial‑mesenchymal transition in human prostate cancer PC‑3 cells

Qiang Liu, Yunyan Wu, Hiroko Seino, Toshihiro Haga, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Pages: 3859-3865
Published online on: 09 August 2018

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Article Open Access

Metformin reverses stem cell‑like HepG2 sphere formation and resistance to sorafenib by attenuating epithelial‑mesenchymal transformation

Yan Feng, Xing Guo, Xinping Huang, Manya Wu, Xin Li, Shushu Wu, Xiaoling Luo
Pages: 3866-3872
Published online on: 03 August 2018

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Article Open Access

Cellular and molecular changes to chondrocytes in an in vitro model of developmental dysplasia of the hip‑an experimental model of DDH with swaddling position

Bo Ning, Rui Jin, Lin Wan, Dahui Wang
Pages: 3873-3881
Published online on: 13 August 2018

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Article Open Access

Shikonin sensitizes wild‑type EGFR NSCLC cells to erlotinib and gefitinib therapy

Yang‑Ling Li, Xiu Hu, Qing‑Yu Li, Fei Wang, Bo Zhang, Ke Ding, Bi‑Qin Tan, Neng‑Ming Lin, Chong Zhang
Pages: 3882-3890
Published online on: 03 August 2018

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Article Open Access

Investigation of key autophagy-and mitophagy-related proteins and gene expression in BALF cells from patients with IPF and RA-ILD

Eirini Vasarmidi, Stella Sarantoulaki, Athina Trachalaki, George Margaritopoulos, Eleni Bibaki, Demetrios A. Spandidos, Nikolaos Tzanakis, Katerina Antoniou
Pages: 3891-3897
Published online on: 06 August 2018

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Article Open Access

A natural ent‑kaurane diterpenoid induces antiproliferation in ovarian cancer cells via ERK1/2 regulation and inhibition of cellular migration and invasion

Jin Sun Lee, Myung Sun Lee, Eun Young Cha, Phuong Thien Thuong, Ji Young Sul, Jun Beom Park, Young Bok Ko
Pages: 3898-3906
Published online on: 09 August 2018

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Article Open Access

Pirfenidone suppresses TGF‑β1‑induced human intestinal fibroblasts activities by regulating proliferation and apoptosis via the inhibition of the Smad and PI3K/AKT signaling pathway

Yanwu Sun, Yiyi Zhang, Pan Chi
Pages: 3907-3913
Published online on: 22 August 2018

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Article Open Access

Elevated expression of PTCD3 correlates with tumor progression and predicts poor prognosis in patients with prostate cancer

Yiqiao Huang, Ganggang Jiang, Xue Liang, Ziquan Lan, Zhengming Su, Hualing Wu, Jinsheng Weng, Xianhan Jiang
Pages: 3914-3922
Published online on: 20 August 2018

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Article Open Access

Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a high‑fat diet

Ping Zhu, Zhi‑Hui Zhang, Xu‑Feng Huang, Yan‑Chuan Shi, Neeta Khandekar, He‑Qin Yang, Shi‑Yu Liang, Zhi‑Yuan Song, Shu Lin
Pages: 3923-3931
Published online on: 10 August 2018

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Article Open Access

Downregulation of Krüppel‑like factor 1 inhibits the metastasis and invasion of cervical cancer cells

Bisheng Zhu, Qisheng Liu, Qi Han, Bohang Zeng, Jingqi Chen, Qiuju Xiao
Pages: 3932-3940
Published online on: 20 August 2018

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Article

Evaluation of the effect of the administration of a glucosamine‑containing supplement on biomarkers for cartilage metabolism in soccer players: A randomized double‑blind placebo‑controlled study

Akifumi Tsuruta, Takumi Horiike, Masafumi Yoshimura, Isao Nagaoka
Pages: 3941-3948
Published online on: 17 August 2018

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Article

Immunohistochemical detection of E7 human papillomavirus protein in pre‑malignant and malignant lesions of the uterine cervix

Lijun Shi, Fengli Han, Chenglong Shi, Yan Huang, Yan Liu, Xiaojia Chang
Pages: 3949-3956
Published online on: 22 August 2018

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Article

Dexmedetomidine pretreatment inhibits cerebral ischemia/reperfusion‑induced neuroinflammation via activation of AMPK

Zhenhong Wang, Wei Zhou, Haiping Dong, Xiaoxiao Ma, Zhenzhou He
Pages: 3957-3964
Published online on: 03 August 2018

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Article

miR‑454‑3p suppresses cell migration and invasion by targeting CPEB1 in human glioblastoma

Xiaobo Hui, Shiming Zhang, Yanping Wang
Pages: 3965-3972
Published online on: 14 August 2018

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Article

Overexpression of Wilms' tumor 1 in skin lesions of psoriasis is associated with abnormal proliferation and apoptosis of keratinocytes

Ruifang Wu, Yuan Liao, Weiyun Shen, Yu Liu, Jianzhong Zhang, Min Zheng, Genghui Chen, Yuwen Su, Ming Zhao, Qianjin Lu
Pages: 3973-3982
Published online on: 16 August 2018

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Article

Antifibrotic potential of bone marrow‑derived mesenchymal stem cells in biliary atresia mice

Jun Lei, Yong Chai, Juhua Xiao, Huakun Hu, Zhiqiang Liu, Yu Xiao, Lijun Yi, Jinshi Huang, Tianxin Xiang, Shouhua Zhang
Pages: 3983-3988
Published online on: 03 August 2018

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Article

Cell‑to‑cell communication via extracellular vesicles among human pancreatic cancer cells derived from the same patient

Mitsuru Chiba, Shiori Kubota, Ayaka Sakai, Satoru Monzen
Pages: 3989-3996
Published online on: 09 August 2018

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Article

Hypoxia‑inducible factor 1α and ROCK1 regulate proliferation and collagen synthesis in hepatic stellate cells under hypoxia

Yibing Hu, Danping Hu, Huanhuan Yu, Wangwang Xu, Rongquan Fu
Pages: 3997-4003
Published online on: 17 August 2018

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Case Report

Two novel mutations in the ANTXR2 gene in a Chinese patient suffering from hyaline fibromatosis syndrome: A case report

Ying Gao, Jinli Bai, Jiancai Wang, Xiaoyan Liu
Pages: 4004-4008
Published online on: 22 August 2018

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Article

Long non‑coding RNA lnc‑GNAT1‑1 inhibits gastric cancer cell proliferation and invasion through the Wnt/β‑catenin pathway in Helicobacter pylori infection

Liping Liu, Tiankui Shuai, Bin Li, Lei Zhu, Xun Li
Pages: 4009-4015
Published online on: 20 August 2018

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Article

Immune thrombocytopenia induces autophagy and suppresses apoptosis in megakaryocytes

Zhanshu Liu, Tonghua Mei
Pages: 4016-4022
Published online on: 09 August 2018

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Article

Geranylgeranyl transferase 1 inhibitor GGTI‑298 enhances the anticancer effect of gefitinib

Bi‑Sheng Liu, Xin‑Yu Dai, Hong‑Wei Xia, Huan‑Ji Xu, Qiu‑Lin Tang, Qi‑Yong Gong, Yong‑Zhan Nie, Feng Bi
Pages: 4023-4029
Published online on: 09 August 2018

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Article

Alpinetin inhibits proliferation and migration of ovarian cancer cells via suppression of STAT3 signaling

Xuezhi Zhao, Xiaohan Guo, Junhua Shen, Dingchao Hua
Pages: 4030-4036
Published online on: 22 August 2018

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Article

Estrogen receptor antagonist fulvestrant inhibits proliferation and promotes apoptosis of prolactinoma cells by regulating the IRE1/XBP1 signaling pathway

Chao Wang, Minghan Bai, Xin Wang, Chunlei Tan, Dongzhi Zhang, Liang Chang, Guofu Li, Lingyu Xie, Jun Su, Yuan Wen
Pages: 4037-4041
Published online on: 10 August 2018

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Article

MicroRNA‑16 inhibits interleukin‑13‑induced inflammatory cytokine secretion and mucus production in nasal epithelial cells by suppressing the IκB kinase β/nuclear factor‑κB pathway

Yueqiu Gao, Zhengzheng Yu
Pages: 4042-4050
Published online on: 17 August 2018

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Article

Differential miRNAomics of the synovial membrane in knee osteoarthritis induced by bilateral anterior cruciate ligament transection in rats Corrigendum in /10.3892/mmr.2019.10758

Jiangtao Zhou, Yina Zhao, Guangwen Wu, Bingbing Lin, Zuanfang Li, Xianxiang Liu
Pages: 4051-4057
Published online on: 13 August 2018

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Article

Salmon cartilage proteoglycan attenuates allergic responses in mouse model of papain‑induced respiratory inflammation

Hisaya K. Ono, Sayuri Yoshimura, Shouhei Hirose, Kouji Narita, Makoto Tsuboi, Krisana Asano, Akio Nakane
Pages: 4058-4064
Published online on: 08 August 2018

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Article

MicroRNA‑424 suppresses the proliferation of hemangioma‑derived endothelial cells by targeting VEGFR‑2

Zhewei Fei, Mingke Qiu, Xianqin Qi, Yuxin Dai, Shuqing Wang, Zhiwei Quan, Yingbin Liu, Jingmin Ou
Pages: 4065-4071
Published online on: 21 August 2018

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Selective activation of inflammation factors by human parvovirus B19 and human bocavirus VP1 unique region on H9c2 cardiomyocyte

Hiong‑Ping Hii, Chun‑Ching Chiu, Di‑Wei Lin, Ya‑Fang Shi, Tsai‑Ching Hsu, Bor‑Show Tzang
Pages: 4072-4078
Published online on: 09 August 2018

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A microRNA‑125a variant, which affects its mature processing, increases the risk of radiation‑induced pneumonitis in patients with non‑small‑cell lung cancer

Hong‑Yan Quan, Tian Yuan, Jian‑Feng Hao
Pages: 4079-4086
Published online on: 20 August 2018

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Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing SIRT1 and SIRT3 expression

Wei Yu, Jinjin Qin, Chunjuan Chen, Yucai Fu, Wei Wang
Pages: 4087-4094
Published online on: 16 August 2018

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Effects of leptin on neurocognitive and motor functions in juvenile rats in a preterm brain damage model

Er‑Cui Feng, Li Jiang
Pages: 4095-4102
Published online on: 14 August 2018

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Corticosteroid therapy in IgA nephropathy with minimal proteinuria and high renal pathological score: A single‑center cohort study

Yuyan Tang, Haidong He, Weiqian Sun, Pin Hu, Xia Chen, Xudong Xu
Pages: 4103-4112
Published online on: 21 August 2018

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MicroRNA‑152 regulates insulin secretion and pancreatic β cell proliferation by targeting PI3Kα

Li Chen, Haiyun Qian, Junli Xue, Juan Zhang, Hao Chen
Pages: 4113-4121
Published online on: 08 August 2018

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Overexpression of miR‑21 is involved in acute monocytic leukemia‑associated angiogenesis by targeting IL‑12

Xue‑Peng He, Peng Chen, Kai Yang, Bing Liu, Yuan Zhang, Fang Wang, Zhi Guo, Xiao‑Dong Liu, Jin‑Xing Lou, Hui‑Ren Chen
Pages: 4122-4128
Published online on: 06 August 2018

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miR‑338‑3p mediates gluconeogenesis via targeting of PP4R1 in hepatocytes

Shuyue Wang, Linfang Li, Xiehui Chen, Xiuqing Huang, Jin Liu, Xuelin Sun, Yang Zhang, Tao Shen, Jun Guo, Yong Man, Weiqing Tang, Lin Dou, Jian Li
Pages: 4129-4137
Published online on: 17 August 2018

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Article

Identification of genes and genetic networks associated with BAG3‑dependent cell proliferation and cell survival in human cervical cancer HeLa cells

Yukihiro Furusawa, Tatsuya Yunoki, Tetsushi Hirano, Satsuki Minagawa, Hironori Izumi, Hisashi Mori, Atsushi Hayashi, Yoshiaki Tabuchi
Pages: 4138-4146
Published online on: 10 August 2018

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Microarray and pattern miner analysis of AXL and VIM gene networks in MDA‑MB‑231 cells

Sudhakar Natarajan, Venil N. Sumantran, Mohan Ranganathan, Suresh Madheswaran
Pages: 4147-4155
Published online on: 20 August 2018

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Retraction Open Access

[Retracted] Combined treatment with extracorporeal shock‑wave therapy and bone marrow mesenchymal stem cell transplantation improves bone repair in a rabbit model of bone nonunion

Tao Fan, Guozhi Huang, Wen Wu, Rong Guo, Qing Zeng
Pages: 4156-4156
Published online on: 09 August 2018

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[Corrigendum] Downregulation of δ opioid receptor by RNA interference enhances the sensitivity of BEL/FU drug‑resistant human hepatocellular carcinoma cells to 5‑FU

Bo Tang, Zhigao Hu, Yang Li, Shengguang Yuan, Zhenran Wang, Shuiping Yu, Songqing He
Pages: 4157-4157
Published online on: 21 August 2018

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Journal Cover
May-2026 Volume 33 Issue 5

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Identification of STMN1 as a lactylation‑related driver of lung cancer progression using Mendelian randomization

Yifan Cai, Yucheng Zhong, Honglin Wang, Shuang Zhu, Fang Huang, Qiuyue Zhang, Shaobo Hu
Article Number: 156
Published online on: 30 March 2026

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Advances in the mechanisms of extracellular vesicles and circulating tumor cells in hepatocellular carcinoma metastasis (Review)

Sitong Yi, Wenxin Liu, Zhaohui Wang
Article Number: 155
Published online on: 30 March 2026

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Diagnostic importance of serum markers in lung cancer

Qichen Liang, Jianmei Song, Haixiang Wei, Lu Ning, Baoyu He, Ziteng Zhang
Article Number: 154
Published online on: 30 March 2026

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VSNL1 attenuates hypoxia‑induced myocardial apoptosis by regulating the CNP/NPRB pathway

Xing Yang, Wenjuan Fang, Rui Chang, Linlin Ma, Xiaoyan Chen, Yanfei Li
Article Number: 153
Published online on: 30 March 2026

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Stabilin‑1: An immunoregulatory scavenger receptor in inflammation and tissue homeostasis (Review)

Xiao-Lei Xiang, Xin-Tong Ye, Yu-Tong Wu, Chen Chen, Chu-Ying Yu, Su-Ting Qian, Dan-Li Cai
Article Number: 152
Published online on: 26 March 2026

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Mechanism and therapeutic prospects of adipose tissue B lymphocytes in obesity and obesity‑associated metabolic diseases (Review)

Hong Wang, Hongyuan Lv, Xiaolin Zhang, Meifang Liu, Liyuan Wang
Article Number: 151
Published online on: 26 March 2026

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Tonsil‑derived mesenchymal stem cell‑derived extracellular vesicles suppress MAPK‑NF‑κB signaling and restore osteogenic differentiation in LPS‑stimulated periodontal ligament fibroblasts

Won-Jung Bae, Su Kang Kim, Han-Soo Kim, Sang Wook Kang, Ju Yeon Ban
Article Number: 150
Published online on: 26 March 2026

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Succinylation modification in diabetes and diabetic complications: Mechanisms and functions (Review)

Yeteng Xiong, Fei Luo, Bingnan Li, Qinfeng Yang
Article Number: 149
Published online on: 26 March 2026

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Polyphyllin II regulates ROS levels and promotes ferroptosis in bladder cancer cells

Quanlai Qiao, Ruifang Guo, Zhonghua Sun, Yaxin Shi, Yuning Xie, Zhiyong Liu
Article Number: 148
Published online on: 26 March 2026

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Veronicastrum sibiricum (L.) Pennell extract alleviates inflammation‑induced muscle atrophy through NLRP3 inflammasome regulation and mitochondrial function restoration

Eunhye Lee, Minjeong Kwon, Ju-Ock Nam
Article Number: 147
Published online on: 26 March 2026

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Role and clinical importance of lactylation in tumors (Review)

Chaowei Zhang, Xinyu Tang, Yuxuan Han, Weiyi Yao, Qing Hong, Yanan Zhu, Na Chen
Article Number: 146
Published online on: 26 March 2026

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Photodynamic therapy: A paradigm shift in overcoming drug‑resistant tuberculosis (Review)

Shuhao Cheng, Yuqing Wang, Jie Yao, Guodong Cheng, Gengzhi Ye, Fapeng Shi, Xiaolei Ma
Article Number: 145
Published online on: 26 March 2026

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Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review)

Yiyu Qin, Yang Zhou
Article Number: 144
Published online on: 26 March 2026

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Retraction Open Access

[Retracted] Na+/K+‑ATPase DR region‑specific antibody protects U251 cells against hypoxia reperfusion‑induced injury via the PI3K/AKT and ERK pathways

Huilin Gong, Pengbiao Lü, Jiangwei Zhang, Dandong Li, Jin Zheng, Jinning Song
Article Number: 143
Published online on: 23 March 2026

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Multi‑omics and their integration in psoriasis research (Review)

Hengyan Zhang, Danping Li, Lijuan Zhu, Heguo Yan, Licong Yang, Xuesong Yang, Ye Zhou
Article Number: 142
Published online on: 23 March 2026

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LDHA protects vascular endothelial cells from oxidative stress‑induced mitochondrial damage via HIF‑1α activation and glycolytic reprogramming

Beibei Dai, Lili Yang, Yu Zhang, Aiyong Yu
Article Number: 141
Published online on: 23 March 2026

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Article

Mechanism of BRCC36 affecting cardiac rupture after acute infarction through the Wnt‑JNK signaling pathway

Yongzhe Guo, Linyan Chen, Shumei Li, Xintao Zhang, Huizhong Lin
Article Number: 140
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway

Ping Niu, Yuxuan Sun, Shiyi Wang, Guang Li, Xiaomin Tang, Jiaqiang Sun, Chunchen Pan, Jingwu Sun
Article Number: 139
Published online on: 19 March 2026

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Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review)

Honghui You, Xiangjun Tang, Xiaoyan Fu, Jiaqi Zhou, Liyuan Wang, Hongxia Zhang, Xianhong Du, Shujuan Liang, Meifang Liu
Article Number: 138
Published online on: 19 March 2026

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Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review)

Yanling Qin, Chenqi Tang, Sen Tan, Guangnan Liu
Article Number: 137
Published online on: 18 March 2026

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Advances in the biological functions of miR‑205 in various diseases (Review)

Dandan Chai, Hua Du, Yingxu Shi
Article Number: 136
Published online on: 18 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Article Number: 135
Published online on: 16 March 2026

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Article Open Access

Precision medicine approach to coronary artery disease: Haptoglobin phenotype‑guided risk assessment

Zhengxin He, Hong Liu, Keran Jia, Daxin Lei, Liyun An, Jia Wang, Fukun Wang
Article Number: 134
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling

Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao
Article Number: 133
Published online on: 11 March 2026

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Glucose‑driven TRIB3 enhances the tumorigenic potential of colon cancer via the PI3K/AKT pathway

Yunting Bai, Xuying Huang, Guangyu An, Yang Ge, Rui Yan, Dan Yu
Article Number: 132
Published online on: 10 March 2026

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[Retracted] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8

Yan-Yan Bai, Jun-Zhi Niu
Article Number: 131
Published online on: 09 March 2026

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Dexmedetomidine protects against myocardial ischemia reperfusion injury by inhibiting the TLR2‑NF‑κB pathway in diabetic mice

Zhengjie Chen, Liangyu Zheng, Gang Chen
Article Number: 130
Published online on: 06 March 2026

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Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis

Yu Han, Siqi Yang, Jing Zhang, Yaoguang Wang, Xi Zhao, Huan Liu
Article Number: 129
Published online on: 05 March 2026

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Retraction Open Access

[Retracted] Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Article Number: 128
Published online on: 05 March 2026

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Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 33 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

Xin-Yu Zhang, Peiqi Hao, Ming-Yue Qi, Hui Guo
Article Number: 171
Published online on: 16 April 2026

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Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

Xue-Jing Lin, Min Yao, Wan-Yun Lin, Qin Yuan, Jie Zhou, Wen-Xuan Xia, Yu-Lei Dong, Miao-Miao Zhang, Ming-Wang Cui, Lin-Han Wu, Diwas Sunchuri, Muhammad Zia Ullah Shahid, Zhu-Ling Guo
Article Number: 170
Published online on: 16 April 2026

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[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
Published online on: 15 April 2026

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Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Article Open Access

Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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