Journal Articles
Review
PI3K/Akt and HIF‑1 signaling pathway in hypoxia‑ischemia (Review)
Zhen Zhang, Li Yao, Jinhua Yang, Zhenkang Wang, Gang Du
Pages: 3547-3554 Published online on: 09 August 2018
Article
Isolation and characterization of minipig perivascular stem cells for bone tissue engineering
Zhen Cui, Chenshuang Li, Nan Jiang, Ci Zhang, Yiran Wang, Hongyun Gao, Yanheng Zhou
Pages: 3555-3562 Published online on: 21 August 2018
Article
Ghrelin improves pilocarpine‑induced cerebral cortex inflammation in epileptic rats by inhibiting NF‑κB and TNF‑α
Kun Han, Qing‑Yi Wang, Cai‑Xia Wang, Shao‑Yong Luan, Wen‑Peng Tian, Yue Wang, Rui‑Yun Zhang
Pages: 3563-3568 Published online on: 10 August 2018
Article
Identification of protein complexes associated with myocardial infarction using a bioinformatics approach
Nianhui Jiao, Yongjie Qi, Changli Lv, Hongjun Li, Fengyong Yang
Pages: 3569-3576 Published online on: 21 August 2018
Article
MicroRNA‑34b promotes proliferation, migration and invasion of Ewing's sarcoma cells by downregulating Notch1
Qunshan Lu, Mei Lu, Dong Li, Shuai Zhang
Pages: 3577-3588 Published online on: 09 August 2018
Article
Establishment of a SVM classifier to predict recurrence of ovarian cancer
Jinting Zhou, Lin Li, Liling Wang, Xiaofang Li, Hui Xing, Li Cheng
Pages: 3589-3598 Published online on: 08 August 2018
Article
Tetraspanin family identified as the central genes detected in gastric cancer using bioinformatics analysis
Weiwei Qi, Libin Sun, Ning Liu, Shufen Zhao, Jing Lv, Wensheng Qiu
Pages: 3599-3610 Published online on: 08 August 2018
Article
Downregulation of Glt25d1 aggravates carbon tetrachloride‑induced acute hepatic injury through activation of the TGF‑β1/Smad2 signaling pathway
Xiaohui Ye, Lingling He, Jiali Ma, Yufeng Li, Manka Zhang, Junru Yang, Jian Zhang, Fan Xiao, Hongshan Wei
Pages: 3611-3618 Published online on: 16 August 2018
Article
Galangin protects human rheumatoid arthritis fibroblast‑like synoviocytes via suppression of the NF‑κB/NLRP3 pathway
Qiang Fu, Yuzhong Gao, Hui Zhao, Zaijun Wang, Jian Wang
Pages: 3619-3624 Published online on: 22 August 2018
Article
Renoprotection of dapagliflozin in human renal proximal tubular cells via the inhibition of the high mobility group box 1‑receptor for advanced glycation end products‑nuclear factor‑κB signaling pathway
Di Yao, Suyu Wang, Min Wang, Weiping Lu
Pages: 3625-3630 Published online on: 17 August 2018
Article
MicroRNA‑675‑3p promotes esophageal squamous cell cancer cell migration and invasion
Qi Xiao, Tianming Chen, Yao Wu, Wenxiu Wu, Yandi Xu, Zhunan Gong, Shilin Chen
Pages: 3631-3640 Published online on: 09 August 2018
Article
Oleanolic acid protects against oxidative stress‑induced human umbilical vein endothelial cell injury by activating AKT/eNOS signaling
Wei Zhang, Jian Feng, Biao Cheng, Qing Lu, Xiaoping Chen
Pages: 3641-3648 Published online on: 03 August 2018
Article
Hydroxysafflor yellow A protects against angiotensin II‑induced hypertrophy
Bin Ni, Donglai Zhou, Yunyan Jing, Shanxin Liu
Pages: 3649-3656 Published online on: 17 August 2018
Article
Dysregulation of lncRNAs GM5524 and GM15645 involved in high‑glucose‑induced podocyte apoptosis and autophagy in diabetic nephropathy
Yamin Feng, Sheng Chen, Jiarong Xu, Qun Zhu, Xiaolong Ye, Dafa Ding, Weihao Yao, Yibing Lu
Pages: 3657-3664 Published online on: 21 August 2018
Article
Absence of Sirt3 aggravates cisplatin nephrotoxicity via enhanced renal tubular apoptosis and inflammation
Dal Kim, Woong Park, Sik Lee, Won Kim, Sung Kwang Park, Kyung Pyo Kang
Pages: 3665-3672 Published online on: 03 August 2018
Article
Transcriptome sequencing identifies key pathways and genes involved in gastric adenocarcinoma
Wenhu Zhang, Shaozhuang Liu, Hanxiang Zhan, Zhibo Yan, Guangyong Zhang
Pages: 3673-3682 Published online on: 09 August 2018
Article
In vitro and in vivo study of the expression of the Syk/Ras/c‑Fos pathway in chronic glomerulonephritis
Jiarong Gao, Liangbing Wei, Junmei Song, Hui Jiang, Yachen Gao, Xi Wu, Shuangzhi Xu
Pages: 3683-3690 Published online on: 03 August 2018
Article
Sinomenine alleviates dextran sulfate sodium‑induced colitis via the Nrf2/NQO‑1 signaling pathway
Yan Zhou, Hanyang Liu, Jun Song, Liang Cao, Liming Tang, Chunjian Qi
Pages: 3691-3698 Published online on: 10 August 2018
Article
Aloperine inhibits proliferation, migration and invasion and induces apoptosis by blocking the Ras signaling pathway in human breast cancer cells
Delong Tian, Yanhai Li, Xinxin Li, Zhenzhen Tian
Pages: 3699-3710 Published online on: 22 August 2018
Article
Therapeutic effects of bee venom on experimental atopic dermatitis
Hyemin Gu, Woon‑Hae Kim, Hyun‑Jin An, Jung‑Yeon Kim, Mi‑Gyeong Gwon, Sang Mi Han, Jaechan Leem, Kwan‑Kyu Park
Pages: 3711-3718 Published online on: 17 August 2018
Article
PDGF‑BB promotes the differentiation and proliferation of MC3T3‑E1 cells through the Src/JAK2 signaling pathway
Qi Liu, Yunfeng Zhou, Zubing Li
Pages: 3719-3726 Published online on: 03 August 2018
Article
Novel prognostic biomarkers of gastric cancer based on gene expression microarray: COL12A1, GSTA3, FGA and FGG
Shijie Duan, Baocheng Gong, Pengliang Wang, Hanwei Huang, Lei Luo, Funan Liu
Pages: 3727-3736 Published online on: 09 August 2018
Article
Bioinformatics analysis to screen for critical genes between survived and non‑survived patients with sepsis
Yanfeng Wu, Lei Zhang, Ying Zhang, Yong Zhen, Shouyue Liu
Pages: 3737-3743 Published online on: 21 August 2018
Article
Tumor promoter role of miR‑647 in gastric cancer via repression of TP73
Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Pages: 3744-3750 Published online on: 06 August 2018
Article
ASCL2 expression contributes to gastric tumor migration and invasion by downregulating miR223 and inducing EMT
Qingsong Zuo, Jie Wang, Chao Chen, Yong Zhang, Dian‑Xu Feng, Ronghua Zhao, Teng Chen
Pages: 3751-3759 Published online on: 08 August 2018
Article
Salidroside mitigates hypoxia/reoxygenation injury by alleviating endoplasmic reticulum stress‑induced apoptosis in H9c2 cardiomyocytes
Meng‑Yao Sun, Da‑Shi Ma, Song Zhao, Lei Wang, Chun‑Ye Ma, Yang Bai
Pages: 3760-3768 Published online on: 20 August 2018
Article
EGFR may participate in immune evasion through regulation of B7‑H5 expression in non‑small cell lung carcinoma
Zhaohui Dong, Lanying Zhang, Wei Xu, Gensheng Zhang
Pages: 3769-3779 Published online on: 08 August 2018
Article
C‑C chemokine receptor type 3 gene knockout alleviates inflammatory responses in allergic rhinitis model mice by regulating the expression of eosinophil granule proteins and immune factors
Xinhua Zhu, Ke Liu, Jialin Wang, Haisen Peng, Qibin Pan, Shuhong Wu, Yinli Jiang, Yuehui Liu
Pages: 3780-3790 Published online on: 10 August 2018
Article
Theaflavins attenuate ethanol‑induced oxidative stress and cell apoptosis in gastric mucosa epithelial cells via downregulation of the mitogen‑activated protein kinase pathway
Zheng Wang, Hesheng Luo, Hong Xia
Pages: 3791-3799 Published online on: 03 August 2018
Article
Silencing of PYGB suppresses growth and promotes the apoptosis of prostate cancer cells via the NF‑κB/Nrf2 signaling pathway
Zhen Wang, Gang Han, Qinghong Liu, Wenyuan Zhang, Jinshan Wang
Pages: 3800-3808 Published online on: 14 August 2018
Article
proBDNF inhibits the proliferation and migration of OLN‑93 oligodendrocytes
Shen Liu, Wei Guo, Hengxing Zhou, Liang Tang, Shiqing Feng, Jin‑Hua Zhong, Xin‑Fu Zhou
Pages: 3809-3817 Published online on: 21 August 2018
Article
Effects of Toll‑like receptor 9 and CpG oligodeoxynucleotides 1826 on sodium taurocholate‑induced acute pancreatitis rats
Liang Sun, Yuanhua Li, Huayou Luo, Kunhua Wang, Li Li, Yujian Zeng
Pages: 3818-3824 Published online on: 03 August 2018
Article
Identification of pathways significantly associated with spondyloarthropathy/ankylosing spondylitis using the sub‑pathway method
Ming Ding, Ting‑Jin Guan, Chuan‑Yin Wei, Bo‑Hua Chen
Pages: 3825-3833 Published online on: 17 August 2018
Article
Effects of Panax ginseng C.A. Meyer extract on the offspring of adult mice with maternal immune activation
Hak‑Jae Kim, Hansol Won, Jiyun Im, Hwayoung Lee, Jiwoo Park, Sanghyun Lee, Young‑Ock Kim, Hyung‑Ki Kim, Jun‑Tack Kwon
Pages: 3834-3842 Published online on: 22 August 2018
Article
Overexpression of KLF5 inhibits puromycin‑induced apoptosis of podocytes
Yang Li, Xiaoni Sui, Xueqing Hu, Zhao Hu
Pages: 3843-3849 Published online on: 09 August 2018
Article
Identification of LINC01279 as a cell cycle‑associated long non‑coding RNA in endometriosis with GBA analysis
Jie Liu, Qi Wang, Rongrong Zhang, Chu Zhang, Jihui Lin, Xiaojie Huang
Pages: 3850-3858 Published online on: 14 August 2018
Article
Correlation between DEC1/DEC2 and epithelial‑mesenchymal transition in human prostate cancer PC‑3 cells
Qiang Liu, Yunyan Wu, Hiroko Seino, Toshihiro Haga, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Pages: 3859-3865 Published online on: 09 August 2018
Article
Metformin reverses stem cell‑like HepG2 sphere formation and resistance to sorafenib by attenuating epithelial‑mesenchymal transformation
Yan Feng, Xing Guo, Xinping Huang, Manya Wu, Xin Li, Shushu Wu, Xiaoling Luo
Pages: 3866-3872 Published online on: 03 August 2018
Article
Cellular and molecular changes to chondrocytes in an in vitro model of developmental dysplasia of the hip‑an experimental model of DDH with swaddling position
Bo Ning, Rui Jin, Lin Wan, Dahui Wang
Pages: 3873-3881 Published online on: 13 August 2018
Article
Shikonin sensitizes wild‑type EGFR NSCLC cells to erlotinib and gefitinib therapy
Yang‑Ling Li, Xiu Hu, Qing‑Yu Li, Fei Wang, Bo Zhang, Ke Ding, Bi‑Qin Tan, Neng‑Ming Lin, Chong Zhang
Pages: 3882-3890 Published online on: 03 August 2018
Article
Investigation of key autophagy-and mitophagy-related proteins and gene expression in BALF cells from patients with IPF and RA-ILD
Eirini Vasarmidi, Stella Sarantoulaki, Athina Trachalaki, George Margaritopoulos, Eleni Bibaki, Demetrios A. Spandidos, Nikolaos Tzanakis, Katerina Antoniou
Pages: 3891-3897 Published online on: 06 August 2018
Article
A natural ent‑kaurane diterpenoid induces antiproliferation in ovarian cancer cells via ERK1/2 regulation and inhibition of cellular migration and invasion
Jin Sun Lee, Myung Sun Lee, Eun Young Cha, Phuong Thien Thuong, Ji Young Sul, Jun Beom Park, Young Bok Ko
Pages: 3898-3906 Published online on: 09 August 2018
Article
Pirfenidone suppresses TGF‑β1‑induced human intestinal fibroblasts activities by regulating proliferation and apoptosis via the inhibition of the Smad and PI3K/AKT signaling pathway
Yanwu Sun, Yiyi Zhang, Pan Chi
Pages: 3907-3913 Published online on: 22 August 2018
Article
Elevated expression of PTCD3 correlates with tumor progression and predicts poor prognosis in patients with prostate cancer
Yiqiao Huang, Ganggang Jiang, Xue Liang, Ziquan Lan, Zhengming Su, Hualing Wu, Jinsheng Weng, Xianhan Jiang
Pages: 3914-3922 Published online on: 20 August 2018
Article
Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a high‑fat diet
Ping Zhu, Zhi‑Hui Zhang, Xu‑Feng Huang, Yan‑Chuan Shi, Neeta Khandekar, He‑Qin Yang, Shi‑Yu Liang, Zhi‑Yuan Song, Shu Lin
Pages: 3923-3931 Published online on: 10 August 2018
Article
Downregulation of Krüppel‑like factor 1 inhibits the metastasis and invasion of cervical cancer cells
Bisheng Zhu, Qisheng Liu, Qi Han, Bohang Zeng, Jingqi Chen, Qiuju Xiao
Pages: 3932-3940 Published online on: 20 August 2018
Article
Evaluation of the effect of the administration of a glucosamine‑containing supplement on biomarkers for cartilage metabolism in soccer players: A randomized double‑blind placebo‑controlled study
Akifumi Tsuruta, Takumi Horiike, Masafumi Yoshimura, Isao Nagaoka
Pages: 3941-3948 Published online on: 17 August 2018
Article
Immunohistochemical detection of E7 human papillomavirus protein in pre‑malignant and malignant lesions of the uterine cervix
Lijun Shi, Fengli Han, Chenglong Shi, Yan Huang, Yan Liu, Xiaojia Chang
Pages: 3949-3956 Published online on: 22 August 2018
Article
Dexmedetomidine pretreatment inhibits cerebral ischemia/reperfusion‑induced neuroinflammation via activation of AMPK
Zhenhong Wang, Wei Zhou, Haiping Dong, Xiaoxiao Ma, Zhenzhou He
Pages: 3957-3964 Published online on: 03 August 2018
Article
miR‑454‑3p suppresses cell migration and invasion by targeting CPEB1 in human glioblastoma
Xiaobo Hui, Shiming Zhang, Yanping Wang
Pages: 3965-3972 Published online on: 14 August 2018
Article
Overexpression of Wilms' tumor 1 in skin lesions of psoriasis is associated with abnormal proliferation and apoptosis of keratinocytes
Ruifang Wu, Yuan Liao, Weiyun Shen, Yu Liu, Jianzhong Zhang, Min Zheng, Genghui Chen, Yuwen Su, Ming Zhao, Qianjin Lu
Pages: 3973-3982 Published online on: 16 August 2018
Article
Antifibrotic potential of bone marrow‑derived mesenchymal stem cells in biliary atresia mice
Jun Lei, Yong Chai, Juhua Xiao, Huakun Hu, Zhiqiang Liu, Yu Xiao, Lijun Yi, Jinshi Huang, Tianxin Xiang, Shouhua Zhang
Pages: 3983-3988 Published online on: 03 August 2018
Article
Cell‑to‑cell communication via extracellular vesicles among human pancreatic cancer cells derived from the same patient
Mitsuru Chiba, Shiori Kubota, Ayaka Sakai, Satoru Monzen
Pages: 3989-3996 Published online on: 09 August 2018
Article
Hypoxia‑inducible factor 1α and ROCK1 regulate proliferation and collagen synthesis in hepatic stellate cells under hypoxia
Yibing Hu, Danping Hu, Huanhuan Yu, Wangwang Xu, Rongquan Fu
Pages: 3997-4003 Published online on: 17 August 2018
Case Report
Two novel mutations in the ANTXR2 gene in a Chinese patient suffering from hyaline fibromatosis syndrome: A case report
Ying Gao, Jinli Bai, Jiancai Wang, Xiaoyan Liu
Pages: 4004-4008 Published online on: 22 August 2018
Article
Long non‑coding RNA lnc‑GNAT1‑1 inhibits gastric cancer cell proliferation and invasion through the Wnt/β‑catenin pathway in Helicobacter pylori infection
Liping Liu, Tiankui Shuai, Bin Li, Lei Zhu, Xun Li
Pages: 4009-4015 Published online on: 20 August 2018
Article
Immune thrombocytopenia induces autophagy and suppresses apoptosis in megakaryocytes
Zhanshu Liu, Tonghua Mei
Pages: 4016-4022 Published online on: 09 August 2018
Article
Geranylgeranyl transferase 1 inhibitor GGTI‑298 enhances the anticancer effect of gefitinib
Bi‑Sheng Liu, Xin‑Yu Dai, Hong‑Wei Xia, Huan‑Ji Xu, Qiu‑Lin Tang, Qi‑Yong Gong, Yong‑Zhan Nie, Feng Bi
Pages: 4023-4029 Published online on: 09 August 2018
Article
Alpinetin inhibits proliferation and migration of ovarian cancer cells via suppression of STAT3 signaling
Xuezhi Zhao, Xiaohan Guo, Junhua Shen, Dingchao Hua
Pages: 4030-4036 Published online on: 22 August 2018
Article
Estrogen receptor antagonist fulvestrant inhibits proliferation and promotes apoptosis of prolactinoma cells by regulating the IRE1/XBP1 signaling pathway
Chao Wang, Minghan Bai, Xin Wang, Chunlei Tan, Dongzhi Zhang, Liang Chang, Guofu Li, Lingyu Xie, Jun Su, Yuan Wen
Pages: 4037-4041 Published online on: 10 August 2018
Article
MicroRNA‑16 inhibits interleukin‑13‑induced inflammatory cytokine secretion and mucus production in nasal epithelial cells by suppressing the IκB kinase β/nuclear factor‑κB pathway
Yueqiu Gao, Zhengzheng Yu
Pages: 4042-4050 Published online on: 17 August 2018
Article
Differential miRNAomics of the synovial membrane in knee osteoarthritis induced by bilateral anterior cruciate ligament transection in rats Corrigendum in /10.3892/mmr.2019.10758
Jiangtao Zhou, Yina Zhao, Guangwen Wu, Bingbing Lin, Zuanfang Li, Xianxiang Liu
Pages: 4051-4057 Published online on: 13 August 2018
Article
Salmon cartilage proteoglycan attenuates allergic responses in mouse model of papain‑induced respiratory inflammation
Hisaya K. Ono, Sayuri Yoshimura, Shouhei Hirose, Kouji Narita, Makoto Tsuboi, Krisana Asano, Akio Nakane
Pages: 4058-4064 Published online on: 08 August 2018
Article
MicroRNA‑424 suppresses the proliferation of hemangioma‑derived endothelial cells by targeting VEGFR‑2
Zhewei Fei, Mingke Qiu, Xianqin Qi, Yuxin Dai, Shuqing Wang, Zhiwei Quan, Yingbin Liu, Jingmin Ou
Pages: 4065-4071 Published online on: 21 August 2018
Article
Selective activation of inflammation factors by human parvovirus B19 and human bocavirus VP1 unique region on H9c2 cardiomyocyte
Hiong‑Ping Hii, Chun‑Ching Chiu, Di‑Wei Lin, Ya‑Fang Shi, Tsai‑Ching Hsu, Bor‑Show Tzang
Pages: 4072-4078 Published online on: 09 August 2018
Article
A microRNA‑125a variant, which affects its mature processing, increases the risk of radiation‑induced pneumonitis in patients with non‑small‑cell lung cancer
Hong‑Yan Quan, Tian Yuan, Jian‑Feng Hao
Pages: 4079-4086 Published online on: 20 August 2018
Article
Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing SIRT1 and SIRT3 expression
Wei Yu, Jinjin Qin, Chunjuan Chen, Yucai Fu, Wei Wang
Pages: 4087-4094 Published online on: 16 August 2018
Article
Effects of leptin on neurocognitive and motor functions in juvenile rats in a preterm brain damage model
Er‑Cui Feng, Li Jiang
Pages: 4095-4102 Published online on: 14 August 2018
Article
Corticosteroid therapy in IgA nephropathy with minimal proteinuria and high renal pathological score: A single‑center cohort study
Yuyan Tang, Haidong He, Weiqian Sun, Pin Hu, Xia Chen, Xudong Xu
Pages: 4103-4112 Published online on: 21 August 2018
Article
MicroRNA‑152 regulates insulin secretion and pancreatic β cell proliferation by targeting PI3Kα
Li Chen, Haiyun Qian, Junli Xue, Juan Zhang, Hao Chen
Pages: 4113-4121 Published online on: 08 August 2018
Article
Overexpression of miR‑21 is involved in acute monocytic leukemia‑associated angiogenesis by targeting IL‑12
Xue‑Peng He, Peng Chen, Kai Yang, Bing Liu, Yuan Zhang, Fang Wang, Zhi Guo, Xiao‑Dong Liu, Jin‑Xing Lou, Hui‑Ren Chen
Pages: 4122-4128 Published online on: 06 August 2018
Article
miR‑338‑3p mediates gluconeogenesis via targeting of PP4R1 in hepatocytes
Shuyue Wang, Linfang Li, Xiehui Chen, Xiuqing Huang, Jin Liu, Xuelin Sun, Yang Zhang, Tao Shen, Jun Guo, Yong Man, Weiqing Tang, Lin Dou, Jian Li
Pages: 4129-4137 Published online on: 17 August 2018
Article
Identification of genes and genetic networks associated with BAG3‑dependent cell proliferation and cell survival in human cervical cancer HeLa cells
Yukihiro Furusawa, Tatsuya Yunoki, Tetsushi Hirano, Satsuki Minagawa, Hironori Izumi, Hisashi Mori, Atsushi Hayashi, Yoshiaki Tabuchi
Pages: 4138-4146 Published online on: 10 August 2018
Article
Microarray and pattern miner analysis of AXL and VIM gene networks in MDA‑MB‑231 cells
Sudhakar Natarajan, Venil N. Sumantran, Mohan Ranganathan, Suresh Madheswaran
Pages: 4147-4155 Published online on: 20 August 2018
Retraction
[Retracted] Combined treatment with extracorporeal shock‑wave therapy and bone marrow mesenchymal stem cell transplantation improves bone repair in a rabbit model of bone nonunion
Tao Fan, Guozhi Huang, Wen Wu, Rong Guo, Qing Zeng
Pages: 4156-4156 Published online on: 09 August 2018
Correction
