Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
January-2020 Volume 21 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2020 Volume 21 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia

  • Authors:
    • Joon Ha Park
    • Ji Hyeon Ahn
    • Dae Won Kim
    • Tae‑Kyeong Lee
    • Cheol Woo Park
    • Young Eun Park
    • Jae‑Chul Lee
    • Hyang‑Ah Lee
    • Go Eun Yang
    • Moo‑Ho Won
    • Choong‑Hyun Lee
  • View Affiliations / Copyright

    Affiliations: Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk 38066, Republic of Korea, Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea, Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangneung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea, Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea, Department of Obstetrics and Gynecology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea, Department of Radiology, Kangwon National University Hospital, Chuncheon, Gangwon 24289, Republic of Korea, Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan, Chungcheongnam‑do 31116, Republic of Korea
    Copyright: © Park et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 107-114
    |
    Published online on: November 20, 2019
       https://doi.org/10.3892/mmr.2019.10828
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Nuclear receptor related 1 protein (Nurr1), a member of the nuclear receptor 4 family of orphan nuclear receptors, has been reported to display anti‑inflammatory properties. The present study investigated the alteration of Nurr1 immunoreactivity in the gerbil hippocampus proper following 5 min of transient global cerebral ischemia. In sham operated gerbils, Nurr1 immunoreactivity was observed in pyramidal neurons in all cornu ammonis 1‑3 (CA1‑3) subfields of the hippocampus proper. In ischemia‑operated gerbils, Nurr1 immunoreactivity was altered in the CA1 subfield. Nurr1 immunoreactivity in CA1 pyramidal neurons gradually decreased until 2 days post‑ischemia, and, at 4 days post‑ischemia, Nurr1 immunoreactivity was concentrated in CA1 pyramidal neurons. Additionally, Nurr1 immunoreactivity was newly expressed in microglia in the CA1 subfield at 4 days post‑ischemia. Conversely, in the CA2/3 subfield, time‑dependent alteration of Nurr1 immunoreactivity was not identified at any time following ischemia. These results indicated that the alteration of Nurr1 expression in the CA1 subfield in the hippocampus may be associated with the death of CA1 pyramidal neurons.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

View References

1 

Globus MY, Busto R, Martinez E, Valdes I, Dietrich WD and Ginsberg MD: Comparative effect of transient global ischemia on extracellular levels of glutamate, glycine, and gamma-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat. J Neurochem. 57:470–478. 1991. View Article : Google Scholar : PubMed/NCBI

2 

Kirino T: Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239:57–69. 1982. View Article : Google Scholar : PubMed/NCBI

3 

Kirino T and Sano K: Selective vulnerability in the gerbil hippocampus following transient ischemia. Acta Neuropathol. 62:201–208. 1984. View Article : Google Scholar : PubMed/NCBI

4 

Kim H, Ahn JH, Song M, Kim DW, Lee TK, Lee JC, Kim YM, Kim JD, Cho JH, Hwang IK, et al: Pretreated fucoidan confers neuroprotection against transient global cerebral ischemic injury in the gerbil hippocampal CA1 area via reducing of glial cell activation and oxidative stress. Biomed Pharmacother. 109:1718–1727. 2019. View Article : Google Scholar : PubMed/NCBI

5 

Lee JC, Park JH, Kim IH, Cho GS, Ahn JH, Tae HJ, Choi SY, Cho JH, Kim DW, Kwon YG, et al: Neuroprotection of ischemic preconditioning is mediated by thioredoxin 2 in the hippocampal CA1 region following a subsequent transient cerebral ischemia. Brain Pathol. 27:276–291. 2017. View Article : Google Scholar : PubMed/NCBI

6 

Park JH, Kim YH, Ahn JH, Choi SY, Hong S, Kim SK, Kang IJ, Kim YM, Lee TK, Won MH and Lee CH: Atomoxetine protects against NMDA Receptor-mediated hippocampal neuronal death following transient global cerebral ischemia. Curr Neurovasc Res. 14:158–168. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Arimatsu Y, Ishida M, Kaneko T, Ichinose S and Omori A: Organization and development of corticocortical associative neurons expressing the orphan nuclear receptor Nurr1. J Comp Neurol. 466:180–196. 2003. View Article : Google Scholar : PubMed/NCBI

8 

Kim CH, Han BS, Moon J, Kim DJ, Shin J, Rajan S, Nguyen QT, Sohn M, Kim WG, Han M, et al: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease. Proc Natl Acad Sci USA. 112:8756–8761. 2015. View Article : Google Scholar : PubMed/NCBI

9 

Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH and Glass CK: A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell. 137:47–59. 2009. View Article : Google Scholar : PubMed/NCBI

10 

Xiao Q, Castillo SO and Nikodem VM: Distribution of messenger RNAs for the orphan nuclear receptors Nurr1 and Nur77 (NGFI-B) in adult rat brain using in situ hybridization. Neuroscience. 75:221–230. 1996. View Article : Google Scholar : PubMed/NCBI

11 

Zou J, Chen Z, Wei X, Chen Z, Fu Y, Yang X, Chen D, Wang R, Jenner P, Lu JH, et al: Cystatin C as a potential therapeutic mediator against Parkinson's disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units. Cell Death Dis. 8:e28542017. View Article : Google Scholar : PubMed/NCBI

12 

Chu Y, Kompoliti K, Cochran EJ, Mufson EJ and Kordower JH: Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra. J Comp Neurol. 450:203–214. 2002. View Article : Google Scholar : PubMed/NCBI

13 

Decressac M, Volakakis N, Bjorklund A and Perlmann T: NURR1 in Parkinson disease-from pathogenesis to therapeutic potential. Nat Rev Neurol. 9:629–636. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Sakurada K, Ohshima-Sakurada M, Palmer TD and Gage FH: Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development. 126:4017–4026. 1999.PubMed/NCBI

15 

Yan W, Chen ZY, Chen JQ and Chen HM: BMP2 promotes the differentiation of neural stem cells into dopaminergic neurons in vitro via miR-145-mediated upregulation of Nurr1 expression. Am J Transl Res. 8:3689–3699. 2016.PubMed/NCBI

16 

Ahn JH, Lee JS, Cho JH, Park JH, Lee TK, Song M, Kim H, Kang SH, Won MH and Lee CH: Age-dependent decrease of Nurr1 protein expression in the gerbil hippocampus. Biomed Rep. 8:517–522. 2018.PubMed/NCBI

17 

Kim JI, Jeon SG, Kim KA, Kim YJ, Song EJ, Choi J, Ahn KJ, Kim CJ, Chung HY, Moon M and Chung H: The pharmacological stimulation of Nurr1 improves cognitive functions via enhancement of adult hippocampal neurogenesis. Stem Cell Res. 17:534–543. 2016. View Article : Google Scholar : PubMed/NCBI

18 

Montes P, Ruiz-Sanchez E, Calvillo M and Rojas P: Active coping of prenatally stressed rats in the forced swimming test: Involvement of the Nurr1 gene. Stress. 19:506–515. 2016. View Article : Google Scholar : PubMed/NCBI

19 

Barneda-Zahonero B, Servitja JM, Badiola N, Miñano-Molina AJ, Fadó R, Saura CA and Rodríguez-Alvarez J: Nurr1 protein is required for N-methyl-D-aspartic acid (NMDA) receptor-mediated neuronal survival. J Biol Chem. 287:11351–11362. 2012. View Article : Google Scholar : PubMed/NCBI

20 

De Miranda BR, Popichak KA, Hammond SL, Jorgensen BA, Phillips AT, Safe S and Tjalkens RB: The Nurr1 Activator 1,1-Bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane blocks inflammatory gene expression in BV-2 microglial cells by inhibiting nuclear factor κB. Mol Pharmacol. 87:1021–1034. 2015. View Article : Google Scholar : PubMed/NCBI

21 

Hammond SL, Safe S and Tjalkens RB: A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro. Neurosci Lett. 607:83–89. 2015. View Article : Google Scholar : PubMed/NCBI

22 

Loppi S, Kolosowska N, Kärkkäinen O, Korhonen P, Huuskonen M, Grubman A, Dhungana H, Wojciechowski S, Pomeshchik Y, Giordano M, et al: HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage. Brain Behav Immun. 73:670–681. 2018. View Article : Google Scholar : PubMed/NCBI

23 

Erdo F, Trapp T, Mies G and Hossmann KA: Immunohistochemical analysis of protein expression after middle cerebral artery occlusion in mice. Acta Neuropathol. 107:127–136. 2004. View Article : Google Scholar : PubMed/NCBI

24 

Honkaniemi J and Sharp FR: Global ischemia induces immediate-early genes encoding zinc finger transcription factors. J Cereb Blood Flow Metab. 16:557–565. 1996. View Article : Google Scholar : PubMed/NCBI

25 

Honkaniemi J, States BA, Weinstein PR, Espinoza J and Sharp FR: Expression of zinc finger immediate early genes in rat brain after permanent middle cerebral artery occlusion. J Cereb Blood Flow Metab. 17:636–646. 1997. View Article : Google Scholar : PubMed/NCBI

26 

Xie X, Peng L, Zhu J, Zhou Y, Li L, Chen Y, Yu S and Zhao Y: miR-145-5p/Nurr1/TNF-a Signaling-induced microglia activation regulates neuron injury of acute cerebral Ischemic/reperfusion in rats. Front Mol Neurosci. 10:3832017. View Article : Google Scholar : PubMed/NCBI

27 

Zhang Z and Yu J: Nurr1 exacerbates cerebral ischemia-reperfusion injury via modulating YAP-INF2-mitochondrial fission pathways. Int J Biochem Cell Biol. 104:149–160. 2018. View Article : Google Scholar : PubMed/NCBI

28 

Ginsberg MD and Busto R: Rodent models of cerebral ischemia. Stroke. 20:1627–1642. 1989. View Article : Google Scholar : PubMed/NCBI

29 

Ahn JH, Shin MC, Kim DW, Kim H, Song M, Lee TK, Lee JC, Kim H, Cho JH, Kim YM, et al: Antioxidant properties of fucoidan alleviate acceleration and exacerbation of hippocampal neuronal death following transient global cerebral ischemia in high-fat diet-induced obese gerbils. Int J Mol Sci. 20(pii): E5542019. View Article : Google Scholar : PubMed/NCBI

30 

Park JH, Noh Y, Kim SS, Ahn JH, Ohk TG, Cho JH, Lee TK, Kim H, Song M, Lee JC, et al: Time-course changes and new expressions of MIP-3a and its receptor, CCR6, in the gerbil hippocampal CA1 area following transient global cerebral ischemia. Neurochem Res. 43:2102–2110. 2018. View Article : Google Scholar : PubMed/NCBI

31 

Park JH, Shin BN, Ahn JH, Cho JH, Kim IH, Kim DW, Won MH, Hong S, Cho JH and Lee CH: Ischemia-induced changes of PRAS40 and p-PRAS40 immunoreactivities in the gerbil hippocampal CA1 region after transient cerebral ischemia. Cell Mol Neurobiol. 36:821–828. 2016. View Article : Google Scholar : PubMed/NCBI

32 

Park JH, Park CW, Ahn JH, Choi SY, Shin MC, Cho JH, Lee TK, Kim IH, Cho JH, Lee JC, et al: Neuroprotection and reduced gliosis by pre- and post-treatments of hydroquinone in a gerbil model of transient cerebral ischemia. Chem Biol Interact. 278:230–238. 2017. View Article : Google Scholar : PubMed/NCBI

33 

Lallier SW, Graf AE, Waidyarante GR and Rogers LK: Nurr1 expression is modified by inflammation in microglia. Neuroreport. 27:1120–1127. 2016. View Article : Google Scholar : PubMed/NCBI

34 

Lu YZ, Lin CH, Cheng FC and Hsueh CM: Molecular mechanisms responsible for microglia-derived protection of Sprague-Dawley rat brain cells during in vitro ischemia. Neurosci Lett. 373:159–164. 2005. View Article : Google Scholar : PubMed/NCBI

35 

Stoll G and Jander S: The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol. 58:233–247. 1999. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Park JH, Ahn JH, Kim DW, Lee TK, Park CW, Park YE, Lee JC, Lee HA, Yang GE, Won MH, Won MH, et al: Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia. Mol Med Rep 21: 107-114, 2020.
APA
Park, J.H., Ahn, J.H., Kim, D.W., Lee, T., Park, C.W., Park, Y.E. ... Lee, C. (2020). Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia. Molecular Medicine Reports, 21, 107-114. https://doi.org/10.3892/mmr.2019.10828
MLA
Park, J. H., Ahn, J. H., Kim, D. W., Lee, T., Park, C. W., Park, Y. E., Lee, J., Lee, H., Yang, G. E., Won, M., Lee, C."Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia". Molecular Medicine Reports 21.1 (2020): 107-114.
Chicago
Park, J. H., Ahn, J. H., Kim, D. W., Lee, T., Park, C. W., Park, Y. E., Lee, J., Lee, H., Yang, G. E., Won, M., Lee, C."Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia". Molecular Medicine Reports 21, no. 1 (2020): 107-114. https://doi.org/10.3892/mmr.2019.10828
Copy and paste a formatted citation
x
Spandidos Publications style
Park JH, Ahn JH, Kim DW, Lee TK, Park CW, Park YE, Lee JC, Lee HA, Yang GE, Won MH, Won MH, et al: Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia. Mol Med Rep 21: 107-114, 2020.
APA
Park, J.H., Ahn, J.H., Kim, D.W., Lee, T., Park, C.W., Park, Y.E. ... Lee, C. (2020). Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia. Molecular Medicine Reports, 21, 107-114. https://doi.org/10.3892/mmr.2019.10828
MLA
Park, J. H., Ahn, J. H., Kim, D. W., Lee, T., Park, C. W., Park, Y. E., Lee, J., Lee, H., Yang, G. E., Won, M., Lee, C."Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia". Molecular Medicine Reports 21.1 (2020): 107-114.
Chicago
Park, J. H., Ahn, J. H., Kim, D. W., Lee, T., Park, C. W., Park, Y. E., Lee, J., Lee, H., Yang, G. E., Won, M., Lee, C."Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia". Molecular Medicine Reports 21, no. 1 (2020): 107-114. https://doi.org/10.3892/mmr.2019.10828
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team