Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
May-2019 Volume 19 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2019 Volume 19 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

The role of ethanol in the pathogenesis of non‑bacterial prostatitis

  • Authors:
    • Feng Liu
    • Lintao Liu
    • Zhong Wang
    • Lin Chen
    • Jianjun Yu
    • Xiaolin Xu
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Shanghai Fengxian District Central Hospital, Shanghai 201499, P.R. China
  • Pages: 3848-3854
    |
    Published online on: February 27, 2019
       https://doi.org/10.3892/mmr.2019.9991
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Chronic prostatitis (CP) is a common disease within the field of urology, and it is difficult to treat. Prostatitis mainly occurs in young men and presents with various clinical symptoms, manifested as urinary frequency, urinary urgency, urinary pain, prolonged urination, dysuria and other urinary abnormalities. There are various forms of the syndrome that can cause discomfort or pain in the perineum, the lower abdomen, the penis, the scrotum and the lumbosacral area. To investigate CP in more detail, animal models are necessary to determine the etiology of prostatitis and develop new, specific drug therapies. In the present study, Sprague Dawley rats that were induced to develop a model of chronic and non‑bacterial prostatitis drank ethanol or water to determine the effects of ethanol on prostatitis. Total antioxidant capacity, the concentration of inflammatory factors, such as tumor necrosis factor‑α and interleukin‑1β, and the expression changes of α1‑adrenoreceptor were measured. The susceptibility of ethanol‑drinking rats to CP was confirmed and some simple mechanism of this susceptibility was investigated to further guide the diagnosis and treatment of patients with prostatitis.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

View References

1 

Rehm J, Samokhvalov AV and Shield KD: Global burden of alcoholic liver diseases. J Hepatol. 59:160–168. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Lee JH, Friso S and Choi SW: Epigenetic mechanisms underlying the link between non-alcoholic fatty liver diseases and nutrition. Nutrients. 6:3303–3325. 2014. View Article : Google Scholar : PubMed/NCBI

3 

Liu YJ, Song GH and Liu GT: Investigation of the effect of traditional Chinese medicine on pain and inflammation in chronic nonbacterial prostatitis in rats. Andrologia. 48:714–722. 2016. View Article : Google Scholar : PubMed/NCBI

4 

Zhao HF, Li X and Jiang XZ: Heat shock protein 9-mediated inflammation reaction in patients with chronic prostatitis with erectile dysfunction. Eur Rev Med Pharmacol Sci. 20:4185–4189. 2016.PubMed/NCBI

5 

Testino G: Alcoholic diseases in hepato-gastroenterology: A point of view. Hepatogastroenterology. 55:371–377. 2008.PubMed/NCBI

6 

Zhang DF, Zhang F, Zhang J, Zhang RM and Li R: Protection effect of trigonelline on liver of rats with non-alcoholic fatty liver diseases. Asian Pac J Trop Med. 8:651–654. 2015. View Article : Google Scholar : PubMed/NCBI

7 

Anderson RU, Wise D, Sawyer T, Glowe P and Orenberg EK: 6-day intensive treatment protocol for refractory chronic prostatitis/chronic pelvic pain syndrome using myofascial release and paradoxical relaxation training. J Urol. 185:1294–1299. 2011. View Article : Google Scholar : PubMed/NCBI

8 

Sahin S, Bicer M, Eren GA, Tas S, Tugcu V, Tasci AI and Cek M: Acupuncture relieves symptoms in chronic prostatitis/chronic pelvic pain syndrome: A randomized, sham-controlled trial. Prostate Cancer Prostatic Dis. 18:249–254. 2015. View Article : Google Scholar : PubMed/NCBI

9 

Zibara K, Awada Z, Dib L, El-Saghir J, Al-Ghadban S, Ibrik A, El-Zein N and El-Sabban M: Anti-angiogenesis therapy and gap junction inhibition reduce MDA-MB-231 breast cancer cell invasion and metastasis in vitro and in vivo. Sci Rep. 5:125982015. View Article : Google Scholar : PubMed/NCBI

10 

Iwamura H, Koie T, Soma O, Matsumoto T, Imai A, Hatakeyama S, Yoneyama T, Hashimoto Y and Ohyama C: Eviprostat has an identical effect compared to pollen extract (Cernilton) in patients with chronic prostatitis/chronic pelvic pain syndrome: A randomized, prospective study. BMC Urol. 15:1202015. View Article : Google Scholar : PubMed/NCBI

11 

Jin JX, Wang HZ, Zhai ZX, Ma BL, Li QF, Xiao N, Wang ZP and Rodriguez R: Transrectal microwave thermotherapy causing a short-time influence on sperm quality in Chinese chronic nonbacterial prostatitis patients. Asian J Androl. 19:548–553. 2016.

12 

Krsmanovic A, Tripp DA, Nickel JC, Shoskes DA, Pontari M, Litwin MS and McNaughton-Collins MF: Psychosocial mechanisms of the pain and quality of life relationship for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Can Urol Assoc J. 8:403–408. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Zijoo R, Dirweesh A, Ordonez FM and Kaji A: Spontaneous Rupture of Urinary Bladder in a Young Alcoholic Male. J Med Cases. 7:245–247. 2016. View Article : Google Scholar

14 

Yatkin E, Bernoulli J, Lammintausta R and Santti R: Fispemifene (Z-2-{2-(4-(4-chloro-1,2-diphenylbut-1-enyl)-phenoxy)ethoxy}-ethanol), a novel selective estrogen receptor modulator, attenuates glandular inflammation in an animal model of chronic nonbacterial prostatitis. J Pharmacol Exp Ther. 327:58–67. 2008. View Article : Google Scholar : PubMed/NCBI

15 

Keetch DW, Humphrey P and Ratliff TL: Development of a mouse model for nonbacterial prostatitis. J Urol. 152:247–250. 1994. View Article : Google Scholar : PubMed/NCBI

16 

Cui D, Han G, Shang Y, Mu L, Long Q and Du Y: The effect of chronic prostatitis on zinc concentration of prostatic fluid and seminal plasma: A systematic review and meta-analysis. Curr Med Res Opin. 31:1763–1769. 2015. View Article : Google Scholar : PubMed/NCBI

17 

Lee G: Chronic Prostatitis: A possible cause of hematospermia. World J Mens Health. 33:103–108. 2015. View Article : Google Scholar : PubMed/NCBI

18 

Magistro G, Wagenlehner FM, Grabe M, Weidner W, Stief CG and Nickel JC: Contemporary management of chronic prostatitis/chronic pelvic pain syndrome. Eur Urol. 69:286–297. 2016. View Article : Google Scholar : PubMed/NCBI

19 

Lai C, Yu X, Zhuo H, Zhou N, Xie Y, He J, Peng Y, Xie X, Luo G, Zhou S, et al: Anti-tumor immune response of folate-conjugated chitosan nanoparticles containing the IP-10 gene in mice with hepatocellular carcinoma. J Biomed Nanotechnol. 10:3576–3589. 2014. View Article : Google Scholar : PubMed/NCBI

20 

Zdrodowska-Stefanow B, Ostaszewska-Puchalska I, Badyda J and Galewska Z: The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis. Arch Immunol Ther Exp (Warsz). 56:277–282. 2008. View Article : Google Scholar : PubMed/NCBI

21 

Delongchamps NB, de la Roza G, Chandan V, Jones R, Sunheimer R, Threatte G, Jumbelic M and Haas GP: Evaluation of prostatitis in autopsied prostates-is chronic inflammation more associated with benign prostatic hyperplasia or cancer? J Urol. 179:1736–1740. 2008. View Article : Google Scholar : PubMed/NCBI

22 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

23 

Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, et al: Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. Neuroimage Clin. 8:493–502. 2015. View Article : Google Scholar : PubMed/NCBI

24 

Thakur V, Talwar M and Singh PP: Low free to total PSA ratio is not a good discriminator of chronic prostatitis and prostate cancer: An Indian experience. Indian J Cancer. 51:335–337. 2014. View Article : Google Scholar : PubMed/NCBI

25 

Giannantoni A and Proietti S: Chronic prostatitis: How to give our best without apposite vagueness. BJU Int. 116:499–500. 2015. View Article : Google Scholar : PubMed/NCBI

26 

Zhang Y, Zheng T, Tu X, Chen X, Wang Z, Chen S, Yang Q, Wan Z, Han D, Xiao H, et al: Erectile dysfunction in chronic prostatitis/chronic pelvic pain syndrome: Outcomes from a multi-center study and risk factor analysis in a single center. PLoS One. 11:e01530542016. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Liu F, Liu L, Wang Z, Chen L, Yu J and Xu X: The role of ethanol in the pathogenesis of non‑bacterial prostatitis. Mol Med Rep 19: 3848-3854, 2019.
APA
Liu, F., Liu, L., Wang, Z., Chen, L., Yu, J., & Xu, X. (2019). The role of ethanol in the pathogenesis of non‑bacterial prostatitis. Molecular Medicine Reports, 19, 3848-3854. https://doi.org/10.3892/mmr.2019.9991
MLA
Liu, F., Liu, L., Wang, Z., Chen, L., Yu, J., Xu, X."The role of ethanol in the pathogenesis of non‑bacterial prostatitis". Molecular Medicine Reports 19.5 (2019): 3848-3854.
Chicago
Liu, F., Liu, L., Wang, Z., Chen, L., Yu, J., Xu, X."The role of ethanol in the pathogenesis of non‑bacterial prostatitis". Molecular Medicine Reports 19, no. 5 (2019): 3848-3854. https://doi.org/10.3892/mmr.2019.9991
Copy and paste a formatted citation
x
Spandidos Publications style
Liu F, Liu L, Wang Z, Chen L, Yu J and Xu X: The role of ethanol in the pathogenesis of non‑bacterial prostatitis. Mol Med Rep 19: 3848-3854, 2019.
APA
Liu, F., Liu, L., Wang, Z., Chen, L., Yu, J., & Xu, X. (2019). The role of ethanol in the pathogenesis of non‑bacterial prostatitis. Molecular Medicine Reports, 19, 3848-3854. https://doi.org/10.3892/mmr.2019.9991
MLA
Liu, F., Liu, L., Wang, Z., Chen, L., Yu, J., Xu, X."The role of ethanol in the pathogenesis of non‑bacterial prostatitis". Molecular Medicine Reports 19.5 (2019): 3848-3854.
Chicago
Liu, F., Liu, L., Wang, Z., Chen, L., Yu, J., Xu, X."The role of ethanol in the pathogenesis of non‑bacterial prostatitis". Molecular Medicine Reports 19, no. 5 (2019): 3848-3854. https://doi.org/10.3892/mmr.2019.9991
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team