|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2018. CA Cancer J Clin. 60:277–300. 2018.
|
|
2
|
Yang LH, Ho YJ, Lin JF, Yeh CW, Kao SH and
Hsu LS: Butein inhibits the proliferation of breast cancer cells
through generation of reactive oxygen species and modulation of ERK
and p38 activities. Mol Med Rep. 6:1126–1132. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Du J, Li L and Zhou S: Microbial
production of cyanophycin: From enzymes to biopolymers. Biotechnol
Adv. 37:1074002019. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Du J, Yang D, Luo ZW and Lee SY: Metabolic
engineering of Escherichia coli for the production of indirubin
from glucose. J Biotechnol. 267:19–28. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Brower V: Back to nature: Extinction of
medicianl plants threathens drug discovery. J Natl Cancer Inst.
100:838–839. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Zhou BG, Wei CS, Zhang S, Zhang Z and Gao
HM: Matrine reversed multidrug resistance of breast cancer
MCF-7/ADR cells through PI3K/AKT signaling pathway. J Cell Biochem.
119:3885–3891. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Zhang YB, Zhan LQ, Li GQ, Wang F, Wang Y,
Li YL, Ye WC and Wang GC: Dimeric matrine-type alkaloids from the
roots of Sophora flavescens and their anti-hepatitis B virus
activities. J Org Chem. 81:6273–6280. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Zhang Y, Zhang H, Yu P, Liu Q, Liu K, Duan
H, Luan G, Yagasaki K and Zhang G: Effects of matrine against the
growth of human lung cancer and hepatoma cells as well as lung
cancer cell migration. Cytotechnology. 59:191–200. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhang Y, Cui L, Guan G, Wang J, Qiu C,
Yang T, Guo Y and Liu Z: Matrine suppresses cardiac fibrosis by
inhibiting the TGF-β/Smad pathway in experimental diabetic
cardiomyopathy. Mol Med Rep. 17:1775–1781. 2018.PubMed/NCBI
|
|
10
|
Zhang P, Wang Z, Chong T and Ji Z: Matrine
inhibits proliferation and induces apoptosis of the
androgen-independent prostate cancer cell line PC-3. Mol Med Rep.
5:783–787. 2012.PubMed/NCBI
|
|
11
|
Zhou N, Li J, Li T, Chen G, Zhang Z and Si
Z: Matrine-induced apoptosis in Hep3B cells via the inhibition of
MDM2. Mol Med Rep. 15:442–450. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Huang J and Xu H: Matrine: Bioactivities
and structural modifications. Curr Top Med Chem. 16:3365–3378.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yong J, Wu X and Lu C: Anticancer advances
of matrine and its derivatives. Curr Pharm Des. 21:3673–3680. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Xue S, Zhou Y, Zhang J, Xiang Z, Liu Y,
Miao T, Liu G, Liu B, Liu X, Shen L, et al: Anemoside B4 exerts
anti-cancer effect by inducing apoptosis and autophagy through
inhibiton of PI3K/Akt/mTOR pathway in hepatocellular carcinoma. Am
J Transl Res. 11:2580–2589. 2019.PubMed/NCBI
|
|
15
|
Guo Z, Guozhang H, Wang H, Li Z and Liu N:
Ampelopsin inhibits human glioma through inducing apoptosis and
autophagy dependent on ROS generation and JNK pathway. Biomed
Pharmacother. 116:1085242019. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Liu J, Fan L, Wang H and Sun G: Autophagy,
a double-edged sword in anti-angiogenesis therapy. Med Oncol.
33:102016. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kaminskyy VO, Piskunova T, Zborovskaya IB,
Tchevkina EM and Zhivotovsky B: Suppression ofbasal autophagy
reduces lung cancer cell proliferation and
enhancescaspase-dependent and -independent apoptosis by stimulating
ROS formation. Autophagy. 8:1032–1044. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Leidal AM, Levine B and Debnath J:
Autophage and the cell biology of age-related disease. Nat Cell
Biol. 20:1338–1348. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Maycotte P, Gearheart CM, Barnard R, Aryal
S, Mulcahy Levy JM, Fosmire SP, Hansen RJ, Morgan MJ, Porter CC,
Gustafson DL and Thorburn A: STAT3-mediated autophagy dependence
identifies subtypes of breast cancer where autophagy inhibition can
be efficacious. Cancer Res. 74:2579–2590. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Lefort S, Joffre C, Kieffer Y, Givel AM,
Bourachot B, Zago G, Bieche I, Dubois T, Meseure D, Vincent-Salomon
A, et al: Inhibition of autophagy as a new means of improving
chemotherapy efficiency in high-LC3B triple-negative breast
cancers. Autophagy. 10:2122–2142. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Cook KL, Wärri A, Soto-Pantoja DR, Clarke
PA, Cruz MI, Zwart A and Clarke R: Hydroxychloroquine inhibits
autophagy to potentiate antiestrogen responsiveness in ER+ breast
cancer. Clin Cancer Res. 20:3222–3232. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yan W, Ma X, Zhao X and Zhang S: Baicalein
induces apoptosis and autophagy of breast cancer cells via
inhibiting PI3K/AKT pathway in vivo and vitro. Drug Des Devel Ther.
12:3961–3972. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Tong Y, Zhang G, Li Y, Xu J, Yuan J, Zhang
B, Hu T and Song G: Corilagin inhibits breast cancer growth via
reactive oxygen species-dependent apoptosis and autophagy. J Cell
Mol Med. 22:3795–3807. 2018. View Article : Google Scholar
|
|
24
|
Xiao X, Ao M, Xu F, Li X, Hu J, Wang Y, Li
D, Zhu X, Xin C and Shi W: Effect of matrine against breast cancer
by downregulating the vascular endothelial growth factor via the
Wnt/β-catenin pathway. Oncol Lett. 15:1691–1697. 2018.PubMed/NCBI
|
|
25
|
Xie Z, Xie Y, Xu Y, Zhou H, Xu W and Dong
Q: Bafilomycin A1 inhibits autophagy and induces apoptosis in MG63
osteosarcoma cells. Mol Med Rep. 10:1103–1107. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Yue Z: Regulation of neuronal autophagy in
axon: Implication of autophagy in axonal function and
dysfunction/degeneration. Autophagy. 3:139–141. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancerstatistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Efferth T, Konkimalla VB, Wang YF,
Sauerbrey A, Meinhardt S, Zintl F, Mattern J and Volm M: Prediction
of broad spectrum resistance of tumors towards anticancer drugs.
Clin Cancer Res. 14:2405–2412. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Niu H, Zhang Y, Wu B, Zhang Y, Jiang H and
He P: Matrine induces the apoptosis of lung cancer cells through
downregulation of inhibitor of apoptosis proteins and the Akt
signaling pathway. Oncol Rep. 32:1087–1093. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Ma K, Huang MY, Guo YX and Hu GQ:
Matrine-induced autophagy counteracts cell apoptosis via the ERK
signaling pathway in osteosarcoma cells. Oncol Lett. 12:1854–1860.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Yang W, Hosford SR, Traphagen NA, Shee K,
Demidenko E, Liu S and Miller TW: Autophagy promotes escape from
phosphatidylinositol 3-kinase inhibition in estrogen
receptor-positive breast cancer. FASEB J. 32:1222–1235. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Yu P, Liu Q, Liu K, Yagasaki K, Wu E and
Zhang G: Matrine suppresses breast cancer cell proliferation and
invasion via VEGF-Akt-NF-kappaB signaling. Cytotechnology.
59:219–229. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Li H, Tan G, Jiang X, Qiao H, Pan S, Jiang
H, Kanwar JR and Sun X: Therapeutic effects of matrine on primary
and metastatic breast cancer. Am J Chin Med. 38:1115–1130. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Li H, Li X, Bai M, Suo Y, Zhang G and Cao
X: Matrine inhibited proliferation and increased apoptosis in human
breast cancer MCF-7 cells via upregulation of Bax and
downregulation of Bcl-2. Int J Clin Exp Pathol. 8:14793–14799.
2015.PubMed/NCBI
|
|
35
|
Tsuji T, Ozasa H, Aoki W, Aburaya S,
Yamamoto Funazo T, Furugaki K, Yoshimura Y, Yamazoe M, Ajimizu H,
Yasuda Y, et al: YAP1 mediates survival of ALK-rearranged lung
cancer cells treated with alectinib via pro-apoptotic protein
regulation. Nat Commun. 11:742020. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wang S, Wang K, Wang H, Han J and Sun H:
Autophagy is essential for flavopiridol-induced cytotoxicity
against MCF-7 breast cancer cells. Mol Med Rep. 16:9715–9720. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Poillet-Perez L and White E: Role of tumor
and host autophagy in cancer metabolism. Genes Dev. 33:610–619.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Chen J, Zhang L, Zhou H, Wang W, Luo Y,
Yang H and Yi H: Inhibition of autophagy promotes cisplatin-induced
apoptotic cell death through Atg5 and Beclin 1 in A549 human lung
cancer cells. Mol Med Rep. 17:6859–6865. 2018.PubMed/NCBI
|
|
39
|
Vidoni C, Ferraresi A, Secomandi E,
Vallino L, Dhanasekaran DN and Isidoro C: Epigenetic targeting of
autophagy for cancer prevention and treatment by natural compounds.
Semin Cancer Biol. 2019.(Epub ahead of print). PubMed/NCBI
|
|
40
|
Udristioiu A and Nica-Badea D: Autophagy
dysfunctions associated with cancer cells and their therapeutic
implications. Biomed Pharmacother. 115:1088922019. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Wang J, Li J, Cao N, Li Z, Han J and Li L:
Resveratrol, an activator of SIRT1, induces protective autophagy in
non-small-cell lung cancer via inhibiting Akt/mTOR and activating
p38-MAPK. Onco Targets Ther. 11:7777–7786. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Wang P, Gao C, Wang W, Yao LP, Zhang J,
Zhang SD, Li J, Fang SH and Fu YJ: Juglone induces apoptosis and
autophagy via modulation of mitogen-activated protein kinase
pathways in human hepatocellular carcinoma cells. Food Chem
Toxicol. 116:40–50. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chi G, Xu D, Zhang B and Yang F: Matrine
induces apoptosis and autophagy of glioma cell line U251 by
regulation of circRNA-104075/BCL-9. Chem Biol Interact.
308:198–205. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Saha S, Panigrahi DP, Patil S and Bhutia
SK: Autophagy in health and disease: A comprehensive review. Biomed
Pharmacother. 104:485–495. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Tazawa H, Kuroda S, Hasei J, Kagawa S and
Fujiwara T: Impact of autophagy in oncolytic adenoviral therapy for
cancer. Int J Mol Sci. 18:14792017. View Article : Google Scholar
|
|
46
|
Cohen-Kaplan V, Livneh I, Avni N, Fabre B,
Ziv T, Kwon YT and Ciechanover A: p62- and ubiquitin-dependent
stress-induced autophagy of the mammalian 26S proteasome. Proc Natl
Acad Sci USA. 113:E74902016. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Chen Y, Zhao X, Li J, Zhang L, Li R, Zhang
H, Liao R, Liu S, Shi W and Liang X: Amino acid starvation promotes
podocyte autophagy through mammalian target of rapamycin inhibition
and transcription factor EB activation. Mol Med Rep. 18:4342–4348.
2018.PubMed/NCBI
|
|
48
|
Heras-Sandoval D, Pérez-Rojas JM,
Hernández-Damián J and Pedraza-Chaverri J: The role of
PI3K/AKT/mTOR pathway in the modulation of autophagy and the
clearance of protein aggregates in neurodegeneration. Cell Signal.
26:2694–2701. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Zhang XR, Wang SY, Sun W and Wei C:
Isoliquiritigenin inhibits proliferation and metastasis of MKN28
gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling
pathway. Mol Med Rep. 18:3429–3436. 2018.PubMed/NCBI
|
|
50
|
Yu H, Qiu Y, Pang X, Li J, Wu S, Yin S,
Han L, Zhang Y, Jin C, Gao X, et al: Lycorine promotes autophagy
and apoptosis via TCRP1/Akt/mTOR axis inactivation in human
hepatocellular carcinoma. Mol Cancer Ther. 16:2711–2723. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Hu JL, Hu XL, Guo AY, Wang CJ, Wen YY and
Cang SD: Endoplasmic reticulum stress promotes autophagy and
apoptosis and reverses chemoresistance in human ovarian cancer
cells. Oncotarget. 8:49380–49394. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Liu X, Zhao P, Wang X, Wang L, Zhu Y and
Gao W: Triptolide induces glioma cell autophagy and apoptosis via
upregulating the ROS/JNK and downregulating the Akt/mTOR signaling
pathways. Front Oncol. 9:3872019. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Liu F, Gao S, Yang Y, Zhao X, Fan Y, Ma W,
Yang D, Yang A and Yu Y: Antitumor activity of curcumin by
modulation of apoptosis and autophagy in human lung cancer A549
cells through inhibiting PI3K/Akt/mTOR pathway. Oncol Rep.
39:1523–1531. 2018.PubMed/NCBI
|
