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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November-2020 Volume 22 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mutations of the cystic fibrosis transmembrane conductance regulator gene in males with congenital bilateral absence of the vas deferens: Reproductive implications and genetic counseling (Review)

Xiangrong Cui, Xueqing Wu, Qiang Li, Xuan Jing
Pages: 3587-3596
Published online on: 24 August 2020

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Article Open Access

In vivo and in vitro anti‑allergic and anti‑inflammatory effects of Dryopteris crassirhizoma through the modulation of the NF‑ĸB signaling pathway in an ovalbumin‑induced allergic asthma mouse model

Chun Hua Piao, Thi Tho Bui, Yan Jing Fan, Thi Van Nguyen, Dong‑Uk Shin, Chang Ho Song, So‑Young Lee, Hee Soon Shin, Hyoung Tae Kim, Ok Hee Chai
Pages: 3597-3606
Published online on: 25 August 2020

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Article Open Access

iTRAQ‑based proteomic analysis reveals potential regulatory networks in dust mite‑related asthma treated with subcutaneous allergen immunotherapy

Jun Bai, Jia‑Yong Zhong, Wang Liao, Ruo Hu, Liang Chen, Xian‑Jin Wu, Shuang‑Ping Liu
Pages: 3607-3620
Published online on: 01 September 2020

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Article Open Access

MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Pages: 3621-3628
Published online on: 02 September 2020

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Article Open Access

Deletion of P110δ promotes the development of myocarditis in ApoE‑deficient mice by increasing mononuclear cell peritoneal infiltration

Qi‑Zhi Zhang, Ai‑Ying Xue, Wei Wei, Ai‑Min Pang, Li‑Na Cao, Fang Liu
Pages: 3629-3634
Published online on: 21 August 2020

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Article Open Access

lncRNA FEZF1‑AS1 promotes migration, invasion and epithelial‑mesenchymal transition of retinoblastoma cells by targeting miR‑1236‑3p

Guanghong Zhang, Wei Yang, Dujun Li, Xiaoyu Li, Juan Huang, Rong Huang, Jihong Luo
Pages: 3635-3644
Published online on: 02 September 2020

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Article Open Access

Differentially expressed genes on the growth of mouse Leydig cells treated with standardised Eurycoma longifolia extract

Nor Amira Khurshid Ahmed, Shern Kwok Lim, Ganesh N. Pandian, Hiroshi Sugiyama, Chong Yew Lee, Boon Yin Khoo, Kit Lam Chan
Pages: 3645-3658
Published online on: 02 September 2020

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Article Open Access

Matrine exerts anti‑breast cancer activity by mediating apoptosis and protective autophagy via the AKT/mTOR pathway in MCF‑7 cells

Jikun Du, Jinwen Li, Daibo Song, Qin Li, Lin Li, Baohong Li, Li Li
Pages: 3659-3666
Published online on: 20 August 2020

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Article Open Access

LncRNA HOTTIP promotes the proliferation and invasion of ovarian cancer cells by activating the MEK/ERK pathway

Jian Liu, Hong‑Bo Hu, Yan‑Ming Liu, Fan‑Xiang Li, Liu‑Ping Zhang, Zong‑Min Liao
Pages: 3667-3676
Published online on: 21 August 2020

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Article Open Access

lncRNA small nucleolar RNA host gene 12 promotes renal cell carcinoma progression by modulating the miR‑200c‑5p/collagen type XI α1 chain pathway

Congjie Xu, Hui Liang, Jiaquan Zhou, Yang Wang, Shuan Liu, Xiaolin Wang, Liangju Su, Xinli Kang
Pages: 3677-3686
Published online on: 02 September 2020

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Article Open Access

Effects of tacrolimus on the TGF‑β1/SMAD signaling pathway in paraquat‑exposed rat alveolar type II epithelial cells

Yingli Ren, Xiangdong Jian, Zhongchen Zhang, Qiong Ning, Baotian Kan, Li Kong
Pages: 3687-3694
Published online on: 21 August 2020

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Article Open Access

miR‑155‑5p downregulation inhibits epithelial‑to‑mesenchymal transition by targeting SIRT1 in human nasal epithelial cells

Niannian Yang, Hao Cheng, Qiao Mo, Xiaobiao Zhou, Minqiang Xie
Pages: 3695-3704
Published online on: 27 August 2020

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Article Open Access

MicroRNA‑23a‑5p mediates the proliferation and differentiation of C2C12 myoblasts

Xue Zhao, Hao Gu, Linghui Wang, Peiwen Zhang, Jingjing Du, Linyuan Shen, Dongmei Jiang, Jinyong Wang, Xuewei Li, Shunhua Zhang, Mingzhou Li, Li Zhu
Pages: 3705-3714
Published online on: 02 September 2020

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Article Open Access

lncRNA SNHG1 attenuates osteogenic differentiation via the miR‑101/DKK1 axis in bone marrow mesenchymal stem cells

Jie Xiang, Hai‑Qing Fu, Zhun Xu, Wei‑Jie Fan, Fei Liu, Bin Chen
Pages: 3715-3722
Published online on: 02 September 2020

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Article Open Access

The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model

Haiyan Cui, Yuanxiong Cheng, Yi He, Weiying Cheng, Wenqu Zhao, Haijin Zhao, Fiona H. Zhou, Liping Wang, Jianghui Dong, Shaoxi Cai
Pages: 3723-3734
Published online on: 21 August 2020

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Article Open Access

Expression profile of lncRNAs and mRNAs in intestinal macrophages

Qais Ahmad Naseer, Lulu Liu, Xiaofei Xue, Siche Chen, Jixiang Chen, Jianguo Qu, Lei Cui, Xiaogang Wang, Shengchun Dang
Pages: 3735-3746
Published online on: 28 August 2020

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Article Open Access

Cancer stem cells as a therapeutic target in 3D tumor models of human chondrosarcoma: An encouraging future for proline rich polypeptide‑1

Caroline J. Granger, Aaron K. Hoyt, Alexandra Moran, Beatrice Becker, Anil  Sedani, Shannon Saigh, Sheila A. Conway, Jeffrey Brown, Karina Galoian
Pages: 3747-3758
Published online on: 02 September 2020

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Article Open Access

Osthole inhibits proliferation of kainic acid‑activated BV‑2 cells by modulating the Notch signaling pathway

Yu‑Zhu Li, Zheng Sun, Hong‑Rui Xu, Qing‑Gao Zhang, Chang‑Qian Zeng
Pages: 3759-3766
Published online on: 24 August 2020

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Article Open Access

Ghrelin system is involved in improvements in glucose metabolism mediated by hyperbaric oxygen treatment in a streptozotocin‑induced type 1 diabetes mouse model

Limin Song, Junhua Yuan, Yuan Liu, Di Zhang, Caishun Zhang, Qian Lin, Manwen Li, Kaizhen Su, Yanrun Li, Guangkai Gao, Ruixia Ma, Jing Dong
Pages: 3767-3776
Published online on: 02 September 2020

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Article Open Access

Functional classification of prostate cancer‑associated miRNAs through CRISPR/Cas9‑mediated gene knockout

Fu‑Neng Jiang, Yu‑Xiang Liang, Wang Wei, Cui‑Yun Zou, Guan‑Xing Chen, Yue‑Ping  Wan, Ze‑Zhen Liu, Yang  Yang, Zhao‑Dong Han, Jian‑Guo Zhu, Wei‑De Zhong
Pages: 3777-3784
Published online on: 07 September 2020

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Article Open Access

A novel identified circular RNA, circ_0000491, aggravates the extracellular matrix of diabetic nephropathy glomerular mesangial cells through suppressing miR‑101b by targeting TGFβRI

Xin Mou, Jia Wei Chenv, Di Yi Zhou, Kaiyuan Liu, Li Jun Chen, Danyang Zhou, Yong Bin Hu
Pages: 3785-3794
Published online on: 02 September 2020

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Article Open Access

MicroRNA‑214 promotes the EMT process in melanoma by downregulating CADM1 expression

Shu‑Jun Wang, Wei‑Wei Li, Cong‑Ji Wen, Yong‑Li Diao, Tian‑Lan Zhao
Pages: 3795-3803
Published online on: 20 August 2020

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Article Open Access

miR‑181d promotes cell proliferation via the IGF1/PI3K/AKT axis in glioma

Dong Tang, Wenhong Gao, Jian Yang, Junhui Liu, Jian Zhao, Jian Ge, Qianxue Chen, Baohui Liu
Pages: 3804-3812
Published online on: 26 August 2020

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Article Open Access

Mesenchymal stem cell‑derived extracellular vesicles prevent neural stem cell hypoxia injury via promoting miR‑210‑3p expression

Fang Li, Jie Zhang, Rui Liao, Yongchun Duan, Lili Tao, Yuwei Xu, Anbao Chen
Pages: 3813-3821
Published online on: 21 August 2020

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Article Open Access

Long non‑coding RNA TP73‑AS1 accelerates the progression and cisplatin resistance of non‑small cell lung cancer by upregulating the expression of TRIM29 via competitively targeting microRNA‑34a‑5p

Shunxiang Luo, Ming Shen, Hui Chen, Weiwei Li, Cong Chen
Pages: 3822-3832
Published online on: 01 September 2020

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Article Open Access

Icariin modulates the sirtuin/NF‑κB pathway and exerts anti‑aging effects in human lung fibroblasts

Changqing Xu, Xuqing Huang, Yueyang Tong, Xiaocheng Feng, Yan Wang, Cancan Wang, Yuyue Jiang
Pages: 3833-3839
Published online on: 24 August 2020

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Article Open Access

Differential expression and inhibitory effects of aquaporins on the development of adenomyosis

Liping Jia, Yuzhu Liu, Yixu Han, Xiaofei Zhou, Fahui Wang
Pages: 3840-3850
Published online on: 02 September 2020

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Article Open Access

Cryptotanshinone alleviates polycystic ovary syndrome in rats by regulating the HMGB1/TLR4/NF‑κB signaling pathway

Yijiao Yang, Ling Yang, Cao Qi, Guohua Hu, Longhui Wang, Zhuojun Sun, Xiaorong Ni
Pages: 3851-3861
Published online on: 28 August 2020

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Article Open Access

Analysis of biomarkers and metabolic pathways in patients with unstable angina based on ultra‑high‑performance liquid chromatography‑quadrupole time‑of‑flight mass spectrometry

Yuechen Liu, Yue Li, Tianpu Zhang, Huan Zhao, Simiao Fan, Xuemeng Cai, Yijia Liu, Zhu Li, Shan Gao, Yubo Li, Chunquan Yu
Pages: 3862-3872
Published online on: 02 September 2020

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Article Open Access

Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A

Yanping Tang, Ji Cao, Zhengmin Cai, Huihua An, Yuqun Li, Yan Peng, Ni Chen, Anqiang Luo, Hao Tao, Kezhi Li
Pages: 3873-3885
Published online on: 26 August 2020

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Article Open Access

SNHG12 inhibits oxygen‑glucose deprivation‑induced neuronal apoptosis via the miR‑181a‑5p/NEGR1 axis

Yangtian Yan, Li Chen, Jiajun Zhou, Liquan Xie
Pages: 3886-3894
Published online on: 24 August 2020

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Article Open Access

KCTD1 mutants in scalp‑ear‑nipple syndrome and AP‑2α P59A in Char syndrome reciprocally abrogate their interactions, but can regulate Wnt/β‑catenin signaling

Lingyu Hu, Li Chen, Liu Yang, Zi Ye, Wenhuan Huang, Xinxin Li, Qing Liu, Junlu Qiu, Xiaofeng Ding
Pages: 3895-3903
Published online on: 24 August 2020

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Article Open Access

MgCl2 promotes mouse mesenchymal stem cell osteogenic differentiation by activating the p38/Osx/Runx2 signaling pathway

Su Ni, Xin‑Bo Xiong, Xin‑Ye Ni
Pages: 3904-3910
Published online on: 02 September 2020

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Article Open Access

MicroRNA‑22 regulates autophagy and apoptosis in cisplatin resistance of osteosarcoma

Chen‑Yang Meng, Zhen‑Qun Zhao, Rui Bai, Wei Zhao, Yu‑Xing Wang, Liang Sun, Chao Sun, Wei Feng, Shi‑Bing Guo
Pages: 3911-3921
Published online on: 20 August 2020

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Article Open Access

Upregulation of centromere protein M promotes tumorigenesis: A potential predictive target for cancer in humans Corrigendum in /10.3892/mmr.2024.13186

Ying Liu, Wenfeng Yu, Peng Ren, Ting Zhang
Pages: 3922-3934
Published online on: 25 August 2020

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Article Open Access

Apatinib sensitizes chemoresistant NSCLC cells to doxetaxel via regulating autophagy and enhances the therapeutic efficacy in advanced and refractory/recurrent NSCLC

Rong Hu, Tao Li, Kaiyuan Hui, Zi Chen, Nan Wang, Xingping Wu, Linyang Ge, Linfu Zhou
Pages: 3935-3943
Published online on: 07 September 2020

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Article Open Access

miR‑183‑5p attenuates cerebral ischemia injury by negatively regulating PTEN

Li Zhu, Xueying Zhou, Shanshan Li, Jianmeng Liu, Jingyan Yang, Xiangyun Fan, Shengnian Zhou
Pages: 3944-3954
Published online on: 07 September 2020

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Article Open Access

Determination of the migration effect and molecular docking of verteporfin in different subtypes of breast cancer cells

Changran Wei, Xiangqi Li
Pages: 3955-3961
Published online on: 02 September 2020

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Article Open Access

Calycosin induces apoptosis via p38‑MAPK pathway‑mediated activation of the mitochondrial apoptotic pathway in human osteosarcoma 143B cells

Wei Tian, Zhi‑Wei Wang, Bao‑Ming Yuan, Yong‑Ge Bao
Pages: 3962-3968
Published online on: 01 September 2020

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Article Open Access

Monoclonal antibody against H1N1 influenza virus hemagglutinin cross reacts with hnRNPA1 and hnRNPA2/B1

Chunyan Guo, Lijun Sun, Shuangping Hao, Xiaoyan Huang, Hanyu Hu, Daoyan Liang, Qing Feng, Yan Li, Yangmeng Feng, Xin Xie, Jun Hu
Pages: 3969-3975
Published online on: 07 September 2020

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Article Open Access

De novo transcriptome sequencing of Paecilomyces tenuipes revealed genes involved in adenosine biosynthesis

Long Han, Yaying Li, Xinyu Meng, Guodong Chu, Yongxin Guo, Muhammad Noman, Yuanyuan Dong, Haiyan Li, Jing Yang, Linna Du
Pages: 3976-3984
Published online on: 02 September 2020

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Article Open Access

Piceatannol suppresses proliferation and induces apoptosis by regulation of the microRNA‑21/phosphatase and tensin homolog/protein kinase B signaling pathway in osteosarcoma cells

Mingyue Zheng, Yaochi Wu
Pages: 3985-3993
Published online on: 02 September 2020

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Article

Gangliosides and CD82 inhibit the motility of colon cancer by downregulating the phosphorylation of EGFR at different tyrosine sites and signaling pathways

Xiaohua Huang, Ying Li, Xin He, Yang Chen, Wei Wei, Xuesong Yang, Keli Ma
Pages: 3994-4002
Published online on: 27 August 2020

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Article

miR‑155 modulates high glucose‑induced cardiac fibrosis via the Nrf2/HO‑1 signaling pathway

Yu Li, Jing‑Zhu Duan, Qian He, Chong‑Quan Wang
Pages: 4003-4016
Published online on: 07 September 2020

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Article

Sox9 promotes renal tubular epithelial‑mesenchymal transition and extracellular matrix aggregation via the PI3K/AKT signaling pathway

Zhiqiang Zhang, Wei Wu, Xiang Fang, Mei Lu, Heyan Wu, Chunlin Gao, Zhengkun Xia
Pages: 4017-4030
Published online on: 02 September 2020

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Article

Histone deacetylase 4 deletion results in abnormal chondrocyte hypertrophy and premature ossification from collagen type 2α1‑expressing cells

Guoqing Du, Chuan Xiang, Xiaowen Sang, Xiang Wang, Ying Shi, Nan Wang, Shaowei Wang, Pengcui Li, Xiaochun Wei, Min Zhang, Lilan Gao, Hongsheng Zhan, Lei Wei
Pages: 4031-4040
Published online on: 27 August 2020

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Article

Histone deacetylase inhibitor valproic acid attenuates high glucose‑induced endoplasmic reticulum stress and apoptosis in NRK‑52E cells

Xinyi Sun, Yuman Sun, Sitong Lin, Yan Xu, Dongming Zhao
Pages: 4041-4047
Published online on: 07 September 2020

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Article

Mutually distinguishing microRNA signatures of breast, ovarian and endometrial cancers in vitro

Marc Hirschfeld, Isabel Ge, Gerta Rücker, Julia Waldschmidt, Sebastian Mayer, Markus Jäger, Matthias Voigt, Bernd Kammerer, Claudia Nöthling, Kai Berner, Daniela Weiss, Jasmin Asberger, Thalia Erbes
Pages: 4048-4060
Published online on: 27 August 2020

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Article

Hydrogen sulfide is a regulator of mammary gland development in prepubescent female mice

Jing Zhang, Jiayi Ye, Cong Yuan, Qin Fu, Fenglin Zhang, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Songbo Wang, Qiang Liu, Qingyan Jiang
Pages: 4061-4069
Published online on: 25 August 2020

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Article

Astragalin alleviates ischemia/reperfusion‑induced brain injury via suppression of endoplasmic reticulum stress

Desheng Liu, Yuntao Gu, Wenting Wang, Wendao Chen
Pages: 4070-4078
Published online on: 20 August 2020

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Retraction Open Access

[Retracted] p53 suppresses stress‑induced cellular senescence via regulation of autophagy under the deprivation of serum

Xinbing Sui, Yong Fang, Haizhou Lou, Kaifeng Wang, Yu Zheng, Fang Lou, Wei  Jin, Yinghua Xu, Wei Chen, Hongming Pan, Xian Wang, Weidong Han
Pages: 4079-4079
Published online on: 01 September 2020

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Review Open Access

Exosomal non‑coding RNAs: Novel biomarkers with emerging clinical applications in gastric cancer (Review)

Xu Lu, Yu Zhang, Guangfei Xie, Ye Ding, Hui Cong, Shihai Xuan
Pages: 4091-4100
Published online on: 17 September 2020

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Review

YAP‑mediated crosstalk between the Wnt and Hippo signaling pathways (Review)

Liya Jiang, Juan Li, Chenxing Zhang, Yufeng Shang, Jun Lin
Pages: 4101-4106
Published online on: 21 September 2020

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Review Open Access

Tumor‑associated macrophages in lung cancer: Friend or foe? (Review)

Fei Xu, Ying Wei, Zhao Tang, Baojun Liu, Jingcheng Dong
Pages: 4107-4115
Published online on: 17 September 2020

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Review

Progress in evaluating the status of hepatitis C infection based on the functional changes of hepatic stellate cells (Review)

Wei Wang, Xuelian Huang, Xuzhou Fan, Jingmei Yan, Jianfeng Luan
Pages: 4116-4124
Published online on: 17 September 2020

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Article Open Access

Human monoclonal anti‑TLR4 antibody negatively regulates lipopolysaccharide‑induced inflammatory responses in mouse macrophages

Yiwen Wang, Dandan Gong, Chuanxia Yao, Feng Zheng, Tingting Zhou, Qingxin Cao, Xuhui Zhu, Maorong Wang, Jin Zhu
Pages: 4125-4134
Published online on: 09 September 2020

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Article Open Access

Vitamin D receptor knockdown attenuates the antiproliferative, pro‑apoptotic and anti‑invasive effect of vitamin D by activating the Wnt/β‑catenin signaling pathway in papillary thyroid cancer

Rui Pang, Ye Xu, Xiaonan Hu, Bo Liu, Jiawei Yu
Pages: 4135-4142
Published online on: 17 September 2020

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Article Open Access

Weissella cibaria CMU exerts an anti‑inflammatory effect by inhibiting Aggregatibacter actinomycetemcomitans‑induced NF‑κB activation in macrophages

Min‑Jeong Kim, Yong‑Ouk You, Joo‑Yi Kang, Hyun‑Jin Kim, Mi‑Sun Kang
Pages: 4143-4150
Published online on: 15 September 2020

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Overexpression of G3BP1 facilitates the progression of colon cancer by activating β‑catenin signaling

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Methylation status of CpG sites in the NOTCH4 promoter region regulates NOTCH4 expression in patients with tetralogy of Fallot

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GSK‑3β inhibition promotes doxorubicin‑induced apoptosis in human cholangiocarcinoma cells via FAK/AKT inhibition

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[Retracted] Glycogen synthase kinase‑3β is required for epithelial‑mesenchymal transition and barrier dysfunction in mouse podocytes under high glucose conditions

Jia Guo, Lili Yang, Yingjin Qiao, Zhangsuo Liu
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February-2026 Volume 33 Issue 2

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CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

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SCImago Journal Rank (SJR): 0.841

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[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

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[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

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Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
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[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

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Article Number: 87
Published online on: 12 January 2026

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[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
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Published online on: 12 January 2026

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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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