Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
presentation
Molecular Medicine Reports

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

  • Selected Issue
  • Current Issue
  • Forthcoming Issue
  • Special Issues
    • Open Special Issues
    • About Special Issues
  • Trending Articles
    • Most Read
    • Most Cited (Dimensions)
      • Past Two Years
      • Total
    • Most Cited (Crossref)
      • Past Year
      • Total
    • Social Media
      • Past Month
      • Past Year
      • Total
  • Information
    • Information for Authors
    • Contact
    • Editorial Policies
    • Editorial Board
    • Aims and Scope
    • Abstracting and Indexing
    • Bibliographic Information
  • Archive
Journal Cover
November-2020 Volume 22 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mutations of the cystic fibrosis transmembrane conductance regulator gene in males with congenital bilateral absence of the vas deferens: Reproductive implications and genetic counseling (Review)

Xiangrong Cui, Xueqing Wu, Qiang Li, Xuan Jing
Pages: 3587-3596
Published online on: 24 August 2020

  • View Full Article Download
Article Open Access

In vivo and in vitro anti‑allergic and anti‑inflammatory effects of Dryopteris crassirhizoma through the modulation of the NF‑ĸB signaling pathway in an ovalbumin‑induced allergic asthma mouse model

Chun Hua Piao, Thi Tho Bui, Yan Jing Fan, Thi Van Nguyen, Dong‑Uk Shin, Chang Ho Song, So‑Young Lee, Hee Soon Shin, Hyoung Tae Kim, Ok Hee Chai
Pages: 3597-3606
Published online on: 25 August 2020

  • View Full Article Download
Article Open Access

iTRAQ‑based proteomic analysis reveals potential regulatory networks in dust mite‑related asthma treated with subcutaneous allergen immunotherapy

Jun Bai, Jia‑Yong Zhong, Wang Liao, Ruo Hu, Liang Chen, Xian‑Jin Wu, Shuang‑Ping Liu
Pages: 3607-3620
Published online on: 01 September 2020

  • View Full Article Download
Article Open Access

MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Pages: 3621-3628
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Deletion of P110δ promotes the development of myocarditis in ApoE‑deficient mice by increasing mononuclear cell peritoneal infiltration

Qi‑Zhi Zhang, Ai‑Ying Xue, Wei Wei, Ai‑Min Pang, Li‑Na Cao, Fang Liu
Pages: 3629-3634
Published online on: 21 August 2020

  • View Full Article Download
Article Open Access

lncRNA FEZF1‑AS1 promotes migration, invasion and epithelial‑mesenchymal transition of retinoblastoma cells by targeting miR‑1236‑3p

Guanghong Zhang, Wei Yang, Dujun Li, Xiaoyu Li, Juan Huang, Rong Huang, Jihong Luo
Pages: 3635-3644
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Differentially expressed genes on the growth of mouse Leydig cells treated with standardised Eurycoma longifolia extract

Nor Amira Khurshid Ahmed, Shern Kwok Lim, Ganesh N. Pandian, Hiroshi Sugiyama, Chong Yew Lee, Boon Yin Khoo, Kit Lam Chan
Pages: 3645-3658
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Matrine exerts anti‑breast cancer activity by mediating apoptosis and protective autophagy via the AKT/mTOR pathway in MCF‑7 cells

Jikun Du, Jinwen Li, Daibo Song, Qin Li, Lin Li, Baohong Li, Li Li
Pages: 3659-3666
Published online on: 20 August 2020

  • View Full Article Download
Article Open Access

LncRNA HOTTIP promotes the proliferation and invasion of ovarian cancer cells by activating the MEK/ERK pathway

Jian Liu, Hong‑Bo Hu, Yan‑Ming Liu, Fan‑Xiang Li, Liu‑Ping Zhang, Zong‑Min Liao
Pages: 3667-3676
Published online on: 21 August 2020

  • View Full Article Download
Article Open Access

lncRNA small nucleolar RNA host gene 12 promotes renal cell carcinoma progression by modulating the miR‑200c‑5p/collagen type XI α1 chain pathway

Congjie Xu, Hui Liang, Jiaquan Zhou, Yang Wang, Shuan Liu, Xiaolin Wang, Liangju Su, Xinli Kang
Pages: 3677-3686
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Effects of tacrolimus on the TGF‑β1/SMAD signaling pathway in paraquat‑exposed rat alveolar type II epithelial cells

Yingli Ren, Xiangdong Jian, Zhongchen Zhang, Qiong Ning, Baotian Kan, Li Kong
Pages: 3687-3694
Published online on: 21 August 2020

  • View Full Article Download
Article Open Access

miR‑155‑5p downregulation inhibits epithelial‑to‑mesenchymal transition by targeting SIRT1 in human nasal epithelial cells

Niannian Yang, Hao Cheng, Qiao Mo, Xiaobiao Zhou, Minqiang Xie
Pages: 3695-3704
Published online on: 27 August 2020

  • View Full Article Download
Article Open Access

MicroRNA‑23a‑5p mediates the proliferation and differentiation of C2C12 myoblasts

Xue Zhao, Hao Gu, Linghui Wang, Peiwen Zhang, Jingjing Du, Linyuan Shen, Dongmei Jiang, Jinyong Wang, Xuewei Li, Shunhua Zhang, Mingzhou Li, Li Zhu
Pages: 3705-3714
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

lncRNA SNHG1 attenuates osteogenic differentiation via the miR‑101/DKK1 axis in bone marrow mesenchymal stem cells

Jie Xiang, Hai‑Qing Fu, Zhun Xu, Wei‑Jie Fan, Fei Liu, Bin Chen
Pages: 3715-3722
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model

Haiyan Cui, Yuanxiong Cheng, Yi He, Weiying Cheng, Wenqu Zhao, Haijin Zhao, Fiona H. Zhou, Liping Wang, Jianghui Dong, Shaoxi Cai
Pages: 3723-3734
Published online on: 21 August 2020

  • View Full Article Download
Article Open Access

Expression profile of lncRNAs and mRNAs in intestinal macrophages

Qais Ahmad Naseer, Lulu Liu, Xiaofei Xue, Siche Chen, Jixiang Chen, Jianguo Qu, Lei Cui, Xiaogang Wang, Shengchun Dang
Pages: 3735-3746
Published online on: 28 August 2020

  • View Full Article Download
Article Open Access

Cancer stem cells as a therapeutic target in 3D tumor models of human chondrosarcoma: An encouraging future for proline rich polypeptide‑1

Caroline J. Granger, Aaron K. Hoyt, Alexandra Moran, Beatrice Becker, Anil  Sedani, Shannon Saigh, Sheila A. Conway, Jeffrey Brown, Karina Galoian
Pages: 3747-3758
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Osthole inhibits proliferation of kainic acid‑activated BV‑2 cells by modulating the Notch signaling pathway

Yu‑Zhu Li, Zheng Sun, Hong‑Rui Xu, Qing‑Gao Zhang, Chang‑Qian Zeng
Pages: 3759-3766
Published online on: 24 August 2020

  • View Full Article Download
Article Open Access

Ghrelin system is involved in improvements in glucose metabolism mediated by hyperbaric oxygen treatment in a streptozotocin‑induced type 1 diabetes mouse model

Limin Song, Junhua Yuan, Yuan Liu, Di Zhang, Caishun Zhang, Qian Lin, Manwen Li, Kaizhen Su, Yanrun Li, Guangkai Gao, Ruixia Ma, Jing Dong
Pages: 3767-3776
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Functional classification of prostate cancer‑associated miRNAs through CRISPR/Cas9‑mediated gene knockout

Fu‑Neng Jiang, Yu‑Xiang Liang, Wang Wei, Cui‑Yun Zou, Guan‑Xing Chen, Yue‑Ping  Wan, Ze‑Zhen Liu, Yang  Yang, Zhao‑Dong Han, Jian‑Guo Zhu, Wei‑De Zhong
Pages: 3777-3784
Published online on: 07 September 2020

  • View Full Article Download
Article Open Access

A novel identified circular RNA, circ_0000491, aggravates the extracellular matrix of diabetic nephropathy glomerular mesangial cells through suppressing miR‑101b by targeting TGFβRI

Xin Mou, Jia Wei Chenv, Di Yi Zhou, Kaiyuan Liu, Li Jun Chen, Danyang Zhou, Yong Bin Hu
Pages: 3785-3794
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

MicroRNA‑214 promotes the EMT process in melanoma by downregulating CADM1 expression

Shu‑Jun Wang, Wei‑Wei Li, Cong‑Ji Wen, Yong‑Li Diao, Tian‑Lan Zhao
Pages: 3795-3803
Published online on: 20 August 2020

  • View Full Article Download
Article Open Access

miR‑181d promotes cell proliferation via the IGF1/PI3K/AKT axis in glioma

Dong Tang, Wenhong Gao, Jian Yang, Junhui Liu, Jian Zhao, Jian Ge, Qianxue Chen, Baohui Liu
Pages: 3804-3812
Published online on: 26 August 2020

  • View Full Article Download
Article Open Access

Mesenchymal stem cell‑derived extracellular vesicles prevent neural stem cell hypoxia injury via promoting miR‑210‑3p expression

Fang Li, Jie Zhang, Rui Liao, Yongchun Duan, Lili Tao, Yuwei Xu, Anbao Chen
Pages: 3813-3821
Published online on: 21 August 2020

  • View Full Article Download
Article Open Access

Long non‑coding RNA TP73‑AS1 accelerates the progression and cisplatin resistance of non‑small cell lung cancer by upregulating the expression of TRIM29 via competitively targeting microRNA‑34a‑5p

Shunxiang Luo, Ming Shen, Hui Chen, Weiwei Li, Cong Chen
Pages: 3822-3832
Published online on: 01 September 2020

  • View Full Article Download
Article Open Access

Icariin modulates the sirtuin/NF‑κB pathway and exerts anti‑aging effects in human lung fibroblasts

Changqing Xu, Xuqing Huang, Yueyang Tong, Xiaocheng Feng, Yan Wang, Cancan Wang, Yuyue Jiang
Pages: 3833-3839
Published online on: 24 August 2020

  • View Full Article Download
Article Open Access

Differential expression and inhibitory effects of aquaporins on the development of adenomyosis

Liping Jia, Yuzhu Liu, Yixu Han, Xiaofei Zhou, Fahui Wang
Pages: 3840-3850
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Cryptotanshinone alleviates polycystic ovary syndrome in rats by regulating the HMGB1/TLR4/NF‑κB signaling pathway

Yijiao Yang, Ling Yang, Cao Qi, Guohua Hu, Longhui Wang, Zhuojun Sun, Xiaorong Ni
Pages: 3851-3861
Published online on: 28 August 2020

  • View Full Article Download
Article Open Access

Analysis of biomarkers and metabolic pathways in patients with unstable angina based on ultra‑high‑performance liquid chromatography‑quadrupole time‑of‑flight mass spectrometry

Yuechen Liu, Yue Li, Tianpu Zhang, Huan Zhao, Simiao Fan, Xuemeng Cai, Yijia Liu, Zhu Li, Shan Gao, Yubo Li, Chunquan Yu
Pages: 3862-3872
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A

Yanping Tang, Ji Cao, Zhengmin Cai, Huihua An, Yuqun Li, Yan Peng, Ni Chen, Anqiang Luo, Hao Tao, Kezhi Li
Pages: 3873-3885
Published online on: 26 August 2020

  • View Full Article Download
Article Open Access

SNHG12 inhibits oxygen‑glucose deprivation‑induced neuronal apoptosis via the miR‑181a‑5p/NEGR1 axis

Yangtian Yan, Li Chen, Jiajun Zhou, Liquan Xie
Pages: 3886-3894
Published online on: 24 August 2020

  • View Full Article Download
Article Open Access

KCTD1 mutants in scalp‑ear‑nipple syndrome and AP‑2α P59A in Char syndrome reciprocally abrogate their interactions, but can regulate Wnt/β‑catenin signaling

Lingyu Hu, Li Chen, Liu Yang, Zi Ye, Wenhuan Huang, Xinxin Li, Qing Liu, Junlu Qiu, Xiaofeng Ding
Pages: 3895-3903
Published online on: 24 August 2020

  • View Full Article Download
Article Open Access

MgCl2 promotes mouse mesenchymal stem cell osteogenic differentiation by activating the p38/Osx/Runx2 signaling pathway

Su Ni, Xin‑Bo Xiong, Xin‑Ye Ni
Pages: 3904-3910
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

MicroRNA‑22 regulates autophagy and apoptosis in cisplatin resistance of osteosarcoma

Chen‑Yang Meng, Zhen‑Qun Zhao, Rui Bai, Wei Zhao, Yu‑Xing Wang, Liang Sun, Chao Sun, Wei Feng, Shi‑Bing Guo
Pages: 3911-3921
Published online on: 20 August 2020

  • View Full Article Download
Article Open Access

Upregulation of centromere protein M promotes tumorigenesis: A potential predictive target for cancer in humans Corrigendum in /10.3892/mmr.2024.13186

Ying Liu, Wenfeng Yu, Peng Ren, Ting Zhang
Pages: 3922-3934
Published online on: 25 August 2020

  • View Full Article Download
Article Open Access

Apatinib sensitizes chemoresistant NSCLC cells to doxetaxel via regulating autophagy and enhances the therapeutic efficacy in advanced and refractory/recurrent NSCLC

Rong Hu, Tao Li, Kaiyuan Hui, Zi Chen, Nan Wang, Xingping Wu, Linyang Ge, Linfu Zhou
Pages: 3935-3943
Published online on: 07 September 2020

  • View Full Article Download
Article Open Access

miR‑183‑5p attenuates cerebral ischemia injury by negatively regulating PTEN

Li Zhu, Xueying Zhou, Shanshan Li, Jianmeng Liu, Jingyan Yang, Xiangyun Fan, Shengnian Zhou
Pages: 3944-3954
Published online on: 07 September 2020

  • View Full Article Download
Article Open Access

Determination of the migration effect and molecular docking of verteporfin in different subtypes of breast cancer cells

Changran Wei, Xiangqi Li
Pages: 3955-3961
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Calycosin induces apoptosis via p38‑MAPK pathway‑mediated activation of the mitochondrial apoptotic pathway in human osteosarcoma 143B cells

Wei Tian, Zhi‑Wei Wang, Bao‑Ming Yuan, Yong‑Ge Bao
Pages: 3962-3968
Published online on: 01 September 2020

  • View Full Article Download
Article Open Access

Monoclonal antibody against H1N1 influenza virus hemagglutinin cross reacts with hnRNPA1 and hnRNPA2/B1

Chunyan Guo, Lijun Sun, Shuangping Hao, Xiaoyan Huang, Hanyu Hu, Daoyan Liang, Qing Feng, Yan Li, Yangmeng Feng, Xin Xie, Jun Hu
Pages: 3969-3975
Published online on: 07 September 2020

  • View Full Article Download
Article Open Access

De novo transcriptome sequencing of Paecilomyces tenuipes revealed genes involved in adenosine biosynthesis

Long Han, Yaying Li, Xinyu Meng, Guodong Chu, Yongxin Guo, Muhammad Noman, Yuanyuan Dong, Haiyan Li, Jing Yang, Linna Du
Pages: 3976-3984
Published online on: 02 September 2020

  • View Full Article Download
Article Open Access

Piceatannol suppresses proliferation and induces apoptosis by regulation of the microRNA‑21/phosphatase and tensin homolog/protein kinase B signaling pathway in osteosarcoma cells

Mingyue Zheng, Yaochi Wu
Pages: 3985-3993
Published online on: 02 September 2020

  • View Full Article Download
Article

Gangliosides and CD82 inhibit the motility of colon cancer by downregulating the phosphorylation of EGFR at different tyrosine sites and signaling pathways

Xiaohua Huang, Ying Li, Xin He, Yang Chen, Wei Wei, Xuesong Yang, Keli Ma
Pages: 3994-4002
Published online on: 27 August 2020

  • View Full Article Download
Article

miR‑155 modulates high glucose‑induced cardiac fibrosis via the Nrf2/HO‑1 signaling pathway

Yu Li, Jing‑Zhu Duan, Qian He, Chong‑Quan Wang
Pages: 4003-4016
Published online on: 07 September 2020

  • View Full Article Download
Article

Sox9 promotes renal tubular epithelial‑mesenchymal transition and extracellular matrix aggregation via the PI3K/AKT signaling pathway

Zhiqiang Zhang, Wei Wu, Xiang Fang, Mei Lu, Heyan Wu, Chunlin Gao, Zhengkun Xia
Pages: 4017-4030
Published online on: 02 September 2020

  • View Full Article Download
Article

Histone deacetylase 4 deletion results in abnormal chondrocyte hypertrophy and premature ossification from collagen type 2α1‑expressing cells

Guoqing Du, Chuan Xiang, Xiaowen Sang, Xiang Wang, Ying Shi, Nan Wang, Shaowei Wang, Pengcui Li, Xiaochun Wei, Min Zhang, Lilan Gao, Hongsheng Zhan, Lei Wei
Pages: 4031-4040
Published online on: 27 August 2020

  • View Full Article Download
Article

Histone deacetylase inhibitor valproic acid attenuates high glucose‑induced endoplasmic reticulum stress and apoptosis in NRK‑52E cells

Xinyi Sun, Yuman Sun, Sitong Lin, Yan Xu, Dongming Zhao
Pages: 4041-4047
Published online on: 07 September 2020

  • View Full Article Download
Article

Mutually distinguishing microRNA signatures of breast, ovarian and endometrial cancers in vitro

Marc Hirschfeld, Isabel Ge, Gerta Rücker, Julia Waldschmidt, Sebastian Mayer, Markus Jäger, Matthias Voigt, Bernd Kammerer, Claudia Nöthling, Kai Berner, Daniela Weiss, Jasmin Asberger, Thalia Erbes
Pages: 4048-4060
Published online on: 27 August 2020

  • View Full Article Download
Article

Hydrogen sulfide is a regulator of mammary gland development in prepubescent female mice

Jing Zhang, Jiayi Ye, Cong Yuan, Qin Fu, Fenglin Zhang, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Songbo Wang, Qiang Liu, Qingyan Jiang
Pages: 4061-4069
Published online on: 25 August 2020

  • View Full Article Download
Article

Astragalin alleviates ischemia/reperfusion‑induced brain injury via suppression of endoplasmic reticulum stress

Desheng Liu, Yuntao Gu, Wenting Wang, Wendao Chen
Pages: 4070-4078
Published online on: 20 August 2020

  • View Full Article Download
Retraction Open Access

[Retracted] p53 suppresses stress‑induced cellular senescence via regulation of autophagy under the deprivation of serum

Xinbing Sui, Yong Fang, Haizhou Lou, Kaifeng Wang, Yu Zheng, Fang Lou, Wei  Jin, Yinghua Xu, Wei Chen, Hongming Pan, Xian Wang, Weidong Han
Pages: 4079-4079
Published online on: 01 September 2020

  • View Full Article Download
Review Open Access

Exosomal non‑coding RNAs: Novel biomarkers with emerging clinical applications in gastric cancer (Review)

Xu Lu, Yu Zhang, Guangfei Xie, Ye Ding, Hui Cong, Shihai Xuan
Pages: 4091-4100
Published online on: 17 September 2020

  • View Full Article Download
Review

YAP‑mediated crosstalk between the Wnt and Hippo signaling pathways (Review)

Liya Jiang, Juan Li, Chenxing Zhang, Yufeng Shang, Jun Lin
Pages: 4101-4106
Published online on: 21 September 2020

  • View Full Article Download
Review Open Access

Tumor‑associated macrophages in lung cancer: Friend or foe? (Review)

Fei Xu, Ying Wei, Zhao Tang, Baojun Liu, Jingcheng Dong
Pages: 4107-4115
Published online on: 17 September 2020

  • View Full Article Download
Review

Progress in evaluating the status of hepatitis C infection based on the functional changes of hepatic stellate cells (Review)

Wei Wang, Xuelian Huang, Xuzhou Fan, Jingmei Yan, Jianfeng Luan
Pages: 4116-4124
Published online on: 17 September 2020

  • View Full Article Download
Article Open Access

Human monoclonal anti‑TLR4 antibody negatively regulates lipopolysaccharide‑induced inflammatory responses in mouse macrophages

Yiwen Wang, Dandan Gong, Chuanxia Yao, Feng Zheng, Tingting Zhou, Qingxin Cao, Xuhui Zhu, Maorong Wang, Jin Zhu
Pages: 4125-4134
Published online on: 09 September 2020

  • View Full Article Download
Article Open Access

Vitamin D receptor knockdown attenuates the antiproliferative, pro‑apoptotic and anti‑invasive effect of vitamin D by activating the Wnt/β‑catenin signaling pathway in papillary thyroid cancer

Rui Pang, Ye Xu, Xiaonan Hu, Bo Liu, Jiawei Yu
Pages: 4135-4142
Published online on: 17 September 2020

  • View Full Article Download
Article Open Access

Weissella cibaria CMU exerts an anti‑inflammatory effect by inhibiting Aggregatibacter actinomycetemcomitans‑induced NF‑κB activation in macrophages

Min‑Jeong Kim, Yong‑Ouk You, Joo‑Yi Kang, Hyun‑Jin Kim, Mi‑Sun Kang
Pages: 4143-4150
Published online on: 15 September 2020

  • View Full Article Download
Article Open Access

Protective effects of valsartan administration on doxorubicin‑induced myocardial injury in rats and the role of oxidative stress and NOX2/NOX4 signaling

Dong Cheng, Libo Chen, Wencheng Tu, Haoren Wang, Qinfu Wang, Lili Meng, Zhu Li, Qin Yu
Pages: 4151-4162
Published online on: 17 September 2020

  • View Full Article Download
Article Open Access

SDF1/CXCR4 axis facilitates the angiogenesis via activating the PI3K/AKT pathway in degenerated discs Retraction in /10.3892/mmr.2024.13331

Hanxiang Zhang, Peng Wang, Xiang Zhang, Wenrui Zhao, Honglei Ren, Zhenming Hu
Pages: 4163-4172
Published online on: 09 September 2020

  • View Full Article Download
Article Open Access

Hypoxia in utero increases the risk of pulmonary hypertension in rat offspring and is associated with vasopressin type‑2 receptor upregulation

Hao Ding, Yuchuan Luo, Ke Hu, Huaying Huang, Pei Liu, Mengqing Xiong, Li Zhu, Jing Yi, Ying Xu
Pages: 4173-4182
Published online on: 23 September 2020

  • View Full Article Download
Article Open Access

Effects of PEG anchors in PEGylated siRNA lipoplexes on in vitro gene‑silencing effects and siRNA biodistribution in mice

Yoshiyuki Hattori, Kyoko Tamaki, Sho Sakasai, Kei‑Ichi Ozaki, Hiraku Onishi
Pages: 4183-4196
Published online on: 18 September 2020

  • View Full Article Download
Article Open Access

Expression and clinical significance of circular RNA hsa_circ_0079787 in the peripheral blood of patients with axial spondyloarthritis

Qing Luo, Biqi Fu, Lu Zhang, Yang Guo, Zikun Huang, Junming Li
Pages: 4197-4206
Published online on: 17 September 2020

  • View Full Article Download
Article Open Access

Microecological investigation and comparison of two clinical methods to evaluate axillary osmidrosis

Hongjiao Du, Shu Ding, Lihua Gao, Jinrong Zeng, Jianyun Lu
Pages: 4207-4212
Published online on: 21 September 2020

  • View Full Article Download
Article Open Access

IKKε deficiency inhibits acute lung injury following renal ischemia reperfusion injury

Chao Meng, Yi Qian, Cui Zhang, Han Liu, Xinwei Mu, Aiping Zhang
Pages: 4213-4220
Published online on: 22 September 2020

  • View Full Article Download
Article Open Access

Neuropilin‑1 as a new potential SARS‑CoV‑2 infection mediator implicated in the neurologic features and central nervous system involvement of COVID‑19

Julie Davies, Harpal S. Randeva, Kamaljit Chatha, Marcia Hall, Demetrios A. Spandidos, Emmanouil Karteris, Ioannis Kyrou
Pages: 4221-4226
Published online on: 15 September 2020

  • View Full Article Download
Article Open Access

Berberine protects against diabetic retinopathy by inhibiting cell apoptosis via deactivation of the NF‑κB signaling pathway

Jiajia Zhai, Zeping Li, Huifeng Zhang, Louyan Ma, Zhengquan Ma, Yi Zhang, Jian Zou, Mo Li, Li Ma, Xin Wang, Xiaomiao Li
Pages: 4227-4235
Published online on: 14 September 2020

  • View Full Article Download
Article Open Access

DDX46 silencing inhibits cell proliferation by activating apoptosis and autophagy in cutaneous squamous cell carcinoma

Quan Lin, Hong-Juan Jin, Duo Zhang, Ling Gao
Pages: 4236-4242
Published online on: 14 September 2020

  • View Full Article Download
Article Open Access

lncRNA TINCR facilities bladder cancer progression via regulating miR‑7 and mTOR

Guoying Xu, Honglan Yang, Meichun Liu, Jintao Niu, Weidong Chen, Xiaojing Tan, Li Sun
Pages: 4243-4253
Published online on: 22 September 2020

  • View Full Article Download
Article Open Access

Hyperbaric oxygen protects against myocardial ischemia‑reperfusion injury through inhibiting mitochondria dysfunction and autophagy

Wan Chen, Liwen Lv, Zhihuan Nong, Xiaoyu Chen, Xiaorong Pan, Chunxia Chen
Pages: 4254-4264
Published online on: 09 September 2020

  • View Full Article Download
Article Open Access

Potential mechanism and key genes involved in mechanical ventilation and lipopolysaccharide‑induced acute lung injury

Wen‑Wen Dong, Zhou Feng, Yun‑Qian Zhang, Zheng‑Shang Ruan, Lai Jiang
Pages: 4265-4277
Published online on: 14 September 2020

  • View Full Article Download
Article Open Access

Effects of ex vivo ischemia time and delayed processing on quality of specimens in tissue biobank

Dan Guo, Anqi Wang, Ting Xie, Sumei Zhang, Dingyan Cao, Jian Sun
Pages: 4278-4288
Published online on: 10 September 2020

  • View Full Article Download
Article Open Access

Pinealectomy increases thermogenesis and decreases lipogenesis

Mikyung Kim, So Min Lee, Jeeyoun Jung, Yun Jin Kim, Kyo Chul Moon, Ji Hae Seo, Tae Kyung Ha, Eunyoung Ha
Pages: 4289-4297
Published online on: 23 September 2020

  • View Full Article Download
Article Open Access

Sufentanil attenuates inflammation and oxidative stress in sepsis-induced acute lung injury by downregulating KNG1 expression

Quan Hu, Qin Wang, Chuangang Han, Yan Yang
Pages: 4298-4306
Published online on: 18 September 2020

  • View Full Article Download
Article Open Access

ITCH regulates oxidative stress induced by high glucose through thioredoxin interacting protein in cultured human lens epithelial cells

Lingfeng Jiang, Wenkai Zhou, Bo Lu, Qichang Yan
Pages: 4307-4319
Published online on: 09 September 2020

  • View Full Article Download
Article Open Access

Caveolin‑1 modulates hypertensive vascular remodeling via regulation of the Notch pathway

Qian Wang, Minxi Lao, Zhen Xu, Meilin Ding, Shaolei Guo, Ling Li
Pages: 4320-4328
Published online on: 14 September 2020

  • View Full Article Download
Article Open Access

AMP‑activated protein kinase family member 5 is an independent prognostic indicator of pancreatic adenocarcinoma: A study based on The Cancer Genome Atlas

Haokai Xu, Jiayan Mao, Xiaodan Yang, Fei Chen, Zhengwei Song, Jianguo Fei, Wei Chen, Zhengxiang Zhong, Xiaoguang Wang
Pages: 4329-4339
Published online on: 10 September 2020

  • View Full Article Download
Article Open Access

Investigating aberrantly expressed microRNAs in peripheral blood mononuclear cells from patients with treatment‑resistant schizophrenia using miRNA sequencing and integrated bioinformatics

Xu You, Yunqiao Zhang, Qing Long, Zijun Liu, Xiao Ma, Zixiang Lu, Wei  Yang, Ziqiao Feng, Wengyu Zhang, Zhaowei Teng, Yong Zeng
Pages: 4340-4350
Published online on: 15 September 2020

  • View Full Article Download
Article Open Access

Effects of botulinum toxin A on endometriosis‑associated pain and its related mechanism Retraction in /10.3892/mmr.2020.11674

Fubo Tian, Wuzhong Cheng, Jianying Hu, Shaoqiang Huang, Shen Sun
Pages: 4351-4359
Published online on: 10 September 2020

  • View Full Article Download
Article Open Access

Effects of local dexmedetomidine administration on the neurotoxicity of ropivacaine for sciatic nerve block in rats

Xing Xue, Jun Fan, Xiaoli Ma, Yongqiang Liu, Xuena Han, Yufang Leng, Jinjia Yu
Pages: 4360-4366
Published online on: 17 September 2020

  • View Full Article Download
Article Open Access

Resveratrol decreases high glucose‑induced apoptosis in renal tubular cells via suppressing endoplasmic reticulum stress

Jing Zhang, Xiong‑Jun Dong, Meng‑Ru Ding, Chun‑Yu You, Xin Lin, Ying Wang, Miao‑Jie‑Yang Wu, Guo‑Fei Xu, Guo‑Dong Wang
Pages: 4367-4375
Published online on: 15 September 2020

  • View Full Article Download
Article Open Access

Neuropeptide Y upregulates Runx2 and osterix and enhances osteogenesis in mouse MC3T3‑E1 cells via an autocrine mechanism

Bo Zhang, Xiaolei Zhang, Juan Xiao, Xuguang Zhou, Yuan Chen, Chunzheng Gao
Pages: 4376-4382
Published online on: 14 September 2020

  • View Full Article Download
Article Open Access

Uncovering potential differentially expressed miRNAs and targeted mRNAs in myocardial infarction based on integrating analysis

Shiai Wang, Na Cao
Pages: 4383-4395
Published online on: 17 September 2020

  • View Full Article Download
Article Open Access

Clinical characteristics and gene mutation analysis of an adult patient with ETFDH‑related multiple acyl‑CoA dehydrogenase deficiency

Chenyi Wang, Haihong Lv, Xia Xu, Yuping Ma, Qian Li
Pages: 4396-4402
Published online on: 18 September 2020

  • View Full Article Download
Article Open Access

Overexpression of G3BP1 facilitates the progression of colon cancer by activating β‑catenin signaling

Yuanzhi Li, Jundong Wang, Sen Zhong, Jun Li, Weiliang Du
Pages: 4403-4411
Published online on: 18 September 2020

  • View Full Article Download
Article Open Access

Methylation status of CpG sites in the NOTCH4 promoter region regulates NOTCH4 expression in patients with tetralogy of Fallot

Yanjie Zhu, Ming Ye, Hongfei Xu, Ruoyi Gu, Xiaojing Ma, Mingwu Chen, Xiaodi Li, Wei Sheng, Guoying Huang
Pages: 4412-4422
Published online on: 24 September 2020

  • View Full Article Download
Article

Preparation of T‑2 toxin‑containing pH‑sensitive liposome and its antitumor activity

Yuan Dong, Guixian Meng, Jian Guo, Moli Yin, Huijing Xu, Yujie Li, Jie Zhu, Wenhe Zhu, Mingguang Li, Yan Li, Huiyan Wang
Pages: 4423-4431
Published online on: 22 September 2020

  • View Full Article Download
Article

GSK‑3β inhibition promotes doxorubicin‑induced apoptosis in human cholangiocarcinoma cells via FAK/AKT inhibition

Lei Li, Yuancai Xiang, Yi Zeng, Bin Xiao, Wenjing Yu, Chunyan Duan, Xianming Xia, Ting Zhang, Yongqiu Zeng, Youping Liu, Rongyang Dai
Pages: 4432-4441
Published online on: 10 September 2020

  • View Full Article Download
Article

miR‑181b‑5p inhibits trophoblast cell migration and invasion through targeting S1PR1 in multiple abnormal trophoblast invasion‑related events

Juan Miao, Yiqing Zhu, Lei Xu, Xiaohao Huang, Xue Zhou
Pages: 4442-4451
Published online on: 17 September 2020

  • View Full Article Download
Retraction Open Access

[Retracted] Glycogen synthase kinase‑3β is required for epithelial‑mesenchymal transition and barrier dysfunction in mouse podocytes under high glucose conditions

Jia Guo, Lili Yang, Yingjin Qiao, Zhangsuo Liu
Pages: 4452-4452
Published online on: 17 September 2020

  • View Full Article Download
Journal Cover
January-2026 Volume 33 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

  • View Full Article Download
Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

  • View Full Article Download
Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

  • View Full Article Download
Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

  • View Full Article Download
Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

  • View Full Article Download
Article Open Access

Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

  • View Full Article Download
Review Open Access

Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

  • View Full Article Download
Article Open Access

Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

  • View Full Article Download
Review Open Access

Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

  • View Full Article Download
Review Open Access

From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

  • View Full Article Download
Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

  • View Full Article Download
Review Open Access

Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

  • View Full Article Download
Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

  • Purchase Full Text Article Purchase Download
Review Open Access

Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

  • View Full Article Download
Article Open Access

Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

  • View Full Article Download
Article Open Access

Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

  • View Full Article Download
Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

  • Purchase Full Text Article Purchase Download
Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

  • View Full Article Download
Article Open Access

Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

  • View Full Article Download
Review Open Access

R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

  • View Full Article Download
Review Open Access

Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

  • View Full Article Download
Article Open Access

PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

  • View Full Article Download
Review Open Access

Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

  • View Full Article Download
Article Open Access

MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

  • View Full Article Download
Journal Cover
February-2026 Volume 33 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

  • Download
Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

  • Download
Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

  • Purchase Download
Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

  • Download
Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

  • Download
Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

  • Download
Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

  • Download
Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

  • Download
Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

  • Download
Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

  • View Full Article Download
Select a topic from the Information tab...
Special issues coming soon...
No data
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team