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![Effect of mmu_circ_0010297
overexpression and knockdown on the proliferation and migration of
mouse cardiac fibroblasts. (A) Overexpression and knockdown
efficiency of mmu_circ_0010297 in cardiac fibroblasts [unpaired
t-test (left) and one-way ANOVA followed by the Sidak method
(right)]. (B) Growth curves of cardiac fibroblasts after
transfection with mmu_circ_0010297 or EV (two-way ANOVA). (C)
Migration of cardiac fibroblasts after transfection with
mmu_circ_0010297 or EV (unpaired t-test). (D) Growth curves of
cardiac fibroblasts after transfection with mmu_circ_0010297 siRNAs
or siNC (two-way ANOVA). (E) Migration of cardiac fibroblasts after
transfection with mmu_circ_0010297 siRNAs or siNC (magnification,
×100×; one-way ANOVA followed by the Sidak method). *P<0.05,
***P<0.001, ****P<0.0001 vs. EV or siNC). circ, circular RNA;
EV, empty vector; NC, negative control; OD, optical density; OE,
overexpression; siRNA/si, small interfering RNA.](/article_images/mmr/32/6/mmr-32-06-13704-g01.jpg)
